48 research outputs found

    Exceptional Points of Degeneracy in Periodic Coupled Waveguides and the Interplay of Gain and Radiation Loss: Theoretical and Experimental Demonstration

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    We present a novel paradigm for dispersion engineering in coupled transmission lines (CTLs) based on exceptional points of degeneracy (EPDs). We develop a theory for fourth-order EPDs consisting of four Floquet-Bloch eigenmodes coalescing into one degenerate eigenmode. We present unique wave propagation properties associated to the EPD and develop a figure of merit to assess the practical occurrence of fourth-order EPDs in CTLs with tolerances and losses. We experimentally verify for the first time the existence of a fourth EPD (the degenerate band edge), through dispersion and transmission measurements in microstrip-based CTLs at microwave frequencies. In addition, we report that based on experimental observation and the developed figure of merit, the EPD features are still observable in structures that radiate (leak energy away), even in the presence of fabrication tolerances and dissipative losses. We investigate the gain and loss balance regime in CTLs as a mean of recovering an EPD in the presence of radiation and/or dissipative losses, without necessarily resorting to Parity-Time (PT)-symmetry regimes. The versatile EPD concept is promising in applications such as high intensity and power-efficiency oscillators, spatial power combiners, or low-threshold oscillators and opens new frontiers for boosting the performance of large coherent sources

    Distributed Degenerate Band Edge Oscillator

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    We propose a new class of oscillators by engineering the dispersion of two-coupled periodic waveguides to exhibit a degenerate band edge (DBE). The DBE is an exceptional point of degeneracy (EPD) of order four, i.e., representing the coalescence of four eigenmodes of a waveguide system without loss and gain. We present a distributed DBE oscillator realized in periodic coupled transmission lines with a unique mode selection scheme that leads to a stable single-frequency oscillation, even in the presence of load variation. The DBE oscillator potentially leads to a boost of the efficiency and performance of RF sources, thanks to the unique features associated to the EPD concept. This class of oscillators is promising for improving discrete-distributed coherent sources and can be extended to radiating structures to achieve a new class of active integrated antenna arrays

    Transabdominal pre-peritoneal (TAPP) versus totally extraperitoneal (TEP) laparoscopic techniques for inguinal hernia repair

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    Background: Hernia repair is one of the most frequently performed surgeries worldwide. Surgical treatment is usually successful in the majority of cases. However, a recurrence rate of 10% is reported irrespective of the surgical approach. Postoperative pain and disability are frequent. Laparoscopic repair has largely replaced open surgery in the treatment of inguinal hernia. Objectives: To evaluate TAPP and TEP laparoscopic techniques for treatment of inguinal hernia repair regarding safety and outcome. Patients and methods: This prospective randomized clinical trial study was carried out on 40 patients with inguinal hernia who underwent laparoscopic repair. Patients were distributed into 2 groups, group A patients had transabdominal preperitoneal (TAPP) repair while group B patients underwent totally extraperitoneal (TEP) repair. Both groups were evaluated according to occurrence of intraoperative complications, operative time, bleeding amount, hospital stay, postoperative pain (visual analogue scale) and duration for return of bowel movements. Results: There was no statistically significant difference between both groups in each studied parameter. However, there was significantly less postoperative pain in TAPP group (p-value= 0.008) and TEP group (p-value= 0.001). Conclusion: In conclusion, both TAPP and TEP achieved similar results in the parameters evaluated during this study. Both approaches can be used in the treatment of inguinal hernia repair

    Intraoperative endomanometric laparoscopic Nissen fundoplication improves postoperative outcomes in large sliding hiatus hernia with severe gastroesophageal reflux disease. A retrospective cohort study

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    Background: Laparoscopic Nissen Fundoplication (LNF) is the gold standard surgical intervention for gastroesophageal reflux disease (GERD). LNF can be followed by recurrent symptoms or complications affecting patient satisfaction. The aim of this study is to assess the value of the intraoperative endomanometric evaluation of esophagogastric competence and pressure combined with LNF in patients with large sliding hiatus hernia (> 5 cm) with severe GERD (DeMeester score >100). Materials and methods: This is a retrospective, multicenter cohort study. Baseline characteristics, postoperative dysphagia and gas bloat syndrome, recurrent symptoms, and satisfaction were collected from a prospectively maintained database. Outcomes analyzed included recurrent reflux symptoms, postoperative side effects, and satisfaction with surgery. Results: 360 patients were stratified into endomanometric LNF (180 patients, LNF+) and LNF alone (180 patients, LNF). Recurrent heartburn (3.9% vs. 8.3%) and recurrent regurgitation (2.2% vs. 5%) showed a lower incidence in the LNF+ group (P=0.012). Postoperative score III recurrent heartburn and score III regurgitations occurred in 0% vs. 3.3% and 0% vs. 2.8% cases in the LNF+ and LNF groups, respectively (P=0.005). Postoperative persistent dysphagia and gas bloat syndrome occurred in 1.75% vs. 5.6% and 0% vs. 3.9% of patients (P=0.001). Score III postoperative persistent dysphagia was 0% vs. 2.8% in the two groups (P=0.007). There was no redo surgery for dysphagia after LNF+. Patient satisfaction at the end of the study was 93.3% vs. 86.7% in both cohorts, respectively (P=0.05). Conclusions: Intraoperative high-resolution manometry (HRM) and endoscopic were feasible in all patients, and the outcomes were favorable from an effectiveness and safety standpoint

    Safety and Efficacy of Myval Implantation in Patients with Severe Bicuspid Aortic Valve Stenosis-A Multicenter Real-World Experience.

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    Bicuspid aortic valve (BAV) is the most common valvular congenital anomaly and is apparent in nearly 50% of candidates for AV replacement. While transcatheter aortic valve implantation (TAVI) is a recommended treatment for patients with symptomatic severe aortic stenosis (AS) at all surgical risk levels, experience with TAVI in severe bicuspid AS is limited. TAVI in BAV is still a challenge due to its association with multiple and complex anatomical considerations. A retrospective study has been conducted to investigate TAVI's procedural and 30-day outcomes using the Myval transcatheter heart valve (THV) (Meril Life Sciences Pvt. Ltd. Vapi, Gujarat, India) in patients with severe bicuspid AS. Data were collected on 68 patients with severe bicuspid AS who underwent TAVI with the Myval THV. Baseline characteristics, procedural, 30-day echocardiographic and clinical outcomes were collected. The mean age and STS PROM score were 72.6 ± 9.4 and 3.54 ± 2.1. Procedures were performed via the transfemoral route in 98.5%. Major vascular complications (1.5%) and life-threatening bleeding (1.5%) occurred infrequently. No patient had coronary obstruction, second valve implantation or conversion to surgery. On 30-day echocardiography, the mean transvalvular gradient and effective orifice area were 9.8 ± 4.5 mmHg and 1.8 ± 0.4 cm2, respectively. None/trace aortic regurgitation occurred in 76.5%, mild AR in 20.5% and moderate AR in 3%. The permanent pacemaker implantation rate was 8.5% and 30-day all-cause death occurred in 3.0% of cases. TAVI with the Myval THV in selected BAV anatomy is associated with favorable short-term hemodynamic and clinical outcomes

    Quantitative aortography for assessment of aortic regurgitation in the era of percutaneous aortic valve replacement

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    Paravalvular leak (PVL) is a shortcoming that can erode the clinical benefits of transcatheter valve replacement (TAVR) and therefore a readily applicable method (aortography) to quantitate PVL objectively and accurately in the interventional suite is appealing to all operators. The ratio between the areas of the time-density curves in the aorta and left ventricular outflow tract (LVOT-AR) defines the regurgitation fraction (RF). This technique has been validated in a mock circulation; a single injection in diastole was further tested in porcine and ovine models. In the clinical setting, LVOT-AR was compared with trans-thoracic and trans-oesophageal echocardiography and cardiac magnetic resonance imaging. LVOT-AR &gt; 17% discriminates mild from moderate aortic regurgitation on echocardiography and confers a poor prognosis in multiple registries, and justifies balloon post-dilatation. The LVOT-AR differentiates the individual performances of many old and novel devices and is being used in ongoing randomized trials and registries.</p

    Quantitative aortography for assessment of aortic regurgitation in the era of percutaneous aortic valve replacement

    Get PDF
    Paravalvular leak (PVL) is a shortcoming that can erode the clinical benefits of transcatheter valve replacement (TAVR) and therefore a readily applicable method (aortography) to quantitate PVL objectively and accurately in the interventional suite is appealing to all operators. The ratio between the areas of the time-density curves in the aorta and left ventricular outflow tract (LVOT-AR) defines the regurgitation fraction (RF). This technique has been validated in a mock circulation; a single injection in diastole was further tested in porcine and ovine models. In the clinical setting, LVOT-AR was compared with trans-thoracic and trans-oesophageal echocardiography and cardiac magnetic resonance imaging. LVOT-AR &gt; 17% discriminates mild from moderate aortic regurgitation on echocardiography and confers a poor prognosis in multiple registries, and justifies balloon post-dilatation. The LVOT-AR differentiates the individual performances of many old and novel devices and is being used in ongoing randomized trials and registries.</p

    Quantitative aortography for assessment of aortic regurgitation in the era of percutaneous aortic valve replacement

    Get PDF
    Paravalvular leak (PVL) is a shortcoming that can erode the clinical benefits of transcatheter valve replacement (TAVR) and therefore a readily applicable method (aortography) to quantitate PVL objectively and accurately in the interventional suite is appealing to all operators. The ratio between the areas of the time-density curves in the aorta and left ventricular outflow tract (LVOT-AR) defines the regurgitation fraction (RF). This technique has been validated in a mock circulation; a single injection in diastole was further tested in porcine and ovine models. In the clinical setting, LVOT-AR was compared with trans-thoracic and trans-oesophageal echocardiography and cardiac magnetic resonance imaging. LVOT-AR > 17% discriminates mild from moderate aortic regurgitation on echocardiography and confers a poor prognosis in multiple registries, and justifies balloon post-dilatation. The LVOT-AR differentiates the individual performances of many old and novel devices and is being used in ongoing randomized trials and registries
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