Selective synthesis of trisubstituted (trifluoromethyl)alkenes via ligand-free Cu-catalyzed syn hydroarylation, hydroalkenylation and hydroallylation of (trifluoromethyl)alkynes

In the presence of catalytic amounts of Cu(OAc)2, the hydroarylation of (trifluoromethyl)alkynes with arylboronic acids proceeded in MeOH at 28 °C to afford diverse β-(trifluoromethyl)styrenes. Moreover, the hydroalkenylation and hydroallylation of a (trifluoromethyl)alkyne using styryl- and allylboronates afforded trifluoromethylated 1,3- and 1,4-dienes.journal articl

Nanoparticle-Assisted Laser Desorption / Ionization Mass Spectrometry (Nano-PALDI MS) with Py-Tag for the Analysis of Small Molecules

We compared two ionization methods, matrix assisted laser desorption/ionization (MALDI) and nanoparticle assisted laser desorption/ionization (Nano-PALDI) mass spectrometry (MS), for the analysis of amino acids derivatized with Py-TagTM that consists pyrylium-based compound. Py-Tag is a useful stable derivatization reagent due to wide mass di erence by Nano-PALDI MS compared to MALDI MS.othe

Performance Test of CW 300 GHz Gyrotron FU CW I

A 300 GHz CWgyrotron FU CWI has been developed and installed in the Research Center for Development of Far-Infrared Region, University of Fukui as a power source of a high frequency material processing system. Its performance was tested and the maximum power of 1.75 kW/ CWhas been attained at the beam voltage of 15 kVand the beam current of 1A. The maximumwindow power efficiency of 15.5%has been obtained at the cathode voltage slightly lower than 15 kV. This gyrotron is designed to deliver a Gaussian beam after mode conversion from the oscillation mode TE_22,8 in the cavity with a complex of an internal radiator and beam shaping mirrors. The detailed measurement with an infrared camera has confirmed that a Gaussian beam is radiated when the magnetic field strength B_c at the cavity is adjusted at a proper value. However, within a range of B_c, the output power is emerged into multiple directions, which suggests simultaneous oscillation of competing cavity modes.othe

Performance Test of CW 300 GHz Gyrotron FU CW I

A 300 GHz CWgyrotron FU CWI has been developed and installed in the Research Center for Development of Far-Infrared Region, University of Fukui as a power source of a high frequency material processing system. Its performance was tested and the maximum power of 1.75 kW/ CWhas been attained at the beam voltage of 15 kVand the beam current of 1A. The maximumwindow power efficiency of 15.5%has been obtained at the cathode voltage slightly lower than 15 kV. This gyrotron is designed to deliver a Gaussian beam after mode conversion from the oscillation mode TE_22,8 in the cavity with a complex of an internal radiator and beam shaping mirrors. The detailed measurement with an infrared camera has confirmed that a Gaussian beam is radiated when the magnetic field strength B_c at the cavity is adjusted at a proper value. However, within a range of B_c, the output power is emerged into multiple directions, which suggests simultaneous oscillation of competing cavity modes.othe

脳虚血性病変に対するより有効で安全な血管内治療の開発

脳梗塞などの虚血性病変に対する血管内治療は近年発展してきている. 特に急性期の頭蓋内主幹動脈塞栓症に対する経動脈的局所血栓溶解術と, 慢性期の頸動脈分岐部狭窄に対する頸動脈ステント留置術は技術の進歩とともに一般に普及しつつある. 我々はより有効でより安全にこれらの治療を行うための研究を行い報告してきた. 我々が開発した血栓溶解術での血栓破砕術と, 頸動脈ステント留置術での塞栓物質吸引法について臨床成績も含めて報告する.departmental bulletin pape