A Demand Based Load Balanced Service Replication Model

Cloud computing allows service users and providers to access the applications, logical resources and files on any computer with ease. A cloud service has three distinct characteristics that differentiate it from traditional hosting. It is sold on demand, typically by the minute or the hour; it is elastic. It is a way to increase capacity or add capabilities on the fly without investing in new infrastructure, training new personnel, or licensing new software. It not only promises reliable services delivered through next-generation data centers that are built on compute and storage virtualization technologies but also addresses the key issues such as scalability, reliability, fault tolerance and file load balancing. The one way to achieve this is through service replication across different machines coupled with load balancing. Though replication potentially improves fault tolerance, it leads to the problem of ensuring consistency of replicas when certain service is updated or modified. However, fewer replicas also decrease concurrency and the level of service availability. A balanced synchronization between replication mechanism and consistency not only ensures highly reliable and fault tolerant system but also improves system performance significantly. This paper presents a load balancing based service replication model that creates a replica on other servers on the basis of number of service accesses. The simulation results indicate that the proposed model reduces the number of messages exchanged for service replication by 25-55% thus improving the overall system performance significantly. Also in case of CPU load based file replication, it is observed that file access time reduces by 5.56%-7.65%

Pregnancy outcome of external cephalic version in singleton pregnancy with breech presentation at term

Background: Breech delivery is associated with poor perinatal outcomes irrespective of the route of delivery. External cephalic version can be a useful tool in management of breech presentation at term by converting it to a cephalic presentation. A study was conducted to evaluate maternal and neonatal outcome of external cephalic version in singleton pregnancies with breech presentation in third trimester.Methods: A prospective observational study was carried out at a tertiary care hospital over a period of 2 years. This study included a total of 65 uncomplicated cases of breech presentation who fulfilled the inclusion criteria. External cephalic version was carried out after 36 weeks of period of gestation in primigravida and after 37 weeks in multigravida women. These patients were followed up till delivery and data was collected and analysed regarding the mode of delivery, maternal and fetal outcome.Results: External cephalic version was successful in 41 patients with a success rate of 63%. Out of them, vaginal delivery could be achieved in 31 cases (75.6%) and LSCS was done for rest of the 10 cases. The success rate was higher in multigravida ladies compared to primigravida ladies. No major procedure related adverse event was noticed in our study.Conclusions: External cephalic version is a very safe and easy procedure which can reduce the rate of cesarean delivery in singleton pregnancies with breech presentation. The results of this study are in favor of wider practice of this procedure in selected cases

EFFECT OF LABETALOL AND ESMOLOL ON ONSET OF ACTION OF ROCURONIUM: A PROSPECTIVE DOUBLE-BLINDED RANDOMIZED CONTROLLED TRIAL

Objective: Labetalol is a non-selective beta blocker which is used for the treatment of hypertension. Its role in controlling the hemodynamic response to tracheal intubation is established. This comparative controlled study was carried out to verify its effects on time to onset of action of rocuronium in comparison to esmolol.Methods: We randomized patients into two groups. Group A receiving injection labetalol 0.25 mg/kg diluted to 10 ml with 0.9% saline and Group B receiving 0.5 mg/kg of esmolol in 10 ml 0.9% saline before surgery. The time to onset of action of rocuronium, systolic blood pressure, and heart rate were recorded. The adverse reactions were observed in the post-operative period.Results: A total of 60 patients were randomized into two groups. At the time of intubation, the systolic blood pressure and heart rate were similar between the two groups. The onset of action of rocuronium was decreased significantly in the labetalol group.Conclusion: Labetalol attenuates the hemodynamic response to tracheal intubation both during intubation. It also slightly decreases the time to onset of action of rocuronium

Load Balancing in Wireless Sensor Network using Divisible Load Theory

In this thesis, optimal load allocation strategies are proposed for a wireless sensor network which is connected in a star topology. The load considered here is of arbitrarily divisible kind, such that each fraction of the job can be distributed and assigned to any processor for computation purpose. Divisible Load Theory emphasizes on how to partition the load among a number of processors and links, such that the load is distributed optimally. Its objective is to partition the load in such a way so that the load can be distributed and processed in the shortest possible time. The existing strategies for both star and bus topologies are investigated. The performance of the suggested strategy is compared with the existing ones and it is found that it reduces the overall communication and processing time if allocation time is considered in the previous strategies

Influence of cocoon stifling and storage on silk reeling performance and quality of muga raw silk

The hot air electrical stifling study has been conducted to evaluate the influence of electrical stifling temperature, stifling hours and duration of cocoon preservation on reeling performance and quality of muga silk . Muga cocoons are reeled on motorised muga silk reeling machine. Electrical hot air stifling has shown superior reeling performance in comparison to smoke stifled and sun dried cocoons. The study has shown that raw silk recovery from electrically hot air stifled cocoons is significantly high in comparison to flame-smoke-sun stifling with a gain of about 6.37%. Similarly there is gradual decline in raw silk recovery (RSR) percentage with increase in storage period of muga cocoon. Thus, RSR has declined by 14.32% in course of 6 months of cocoon storage. Tenacity is found higher in October crop (average 3.36 g/den), while it is average 2.83 g/den in crop of May month. Muga raw silk yarn has lost elongation with extended storage of yarn. In fresh muga raw silk yarn, elongation is found 37.55%, while in one year old stored muga raw silk yarn elongation has come down to 33.02%. Thus, the study recommends stifling muga cocoon by hot air stifling for four hours. Cocoon preservation time needs to be minimized and muga silk yarn of October (Kotia) crop with high tenacity should be used as warp yarn in weavin

Influence of cocoon stifling and storage on silk reeling performance and quality of muga raw silk

359-361The hot air electrical stifling study has been conducted to evaluate the influence of electrical stifling temperature, stifling hours and duration of cocoon preservation on reeling performance and quality of muga silk . Muga cocoons are reeled on motorised muga silk reeling machine. Electrical hot air stifling has shown superior reeling performance in comparison to smoke stifled and sun dried cocoons. The study has shown that raw silk recovery from electrically hot air stifled cocoons is significantly high in comparison to flame-smoke-sun stifling with a gain of about 6.37%. Similarly there is gradual decline in raw silk recovery (RSR) percentage with increase in storage period of muga cocoon. Thus, RSR has declined by 14.32% in course of 6 months of cocoon storage. Tenacity is found higher in October crop (average 3.36 g/den), while it is average 2.83 g/den in crop of May month. Muga raw silk yarn has lost elongation with extended storage of yarn. In fresh muga raw silk yarn, elongation is found 37.55%, while in one year old stored muga raw silk yarn elongation has come down to 33.02%. Thus, the study recommends stifling muga cocoon by hot air stifling for four hours. Cocoon preservation time needs to be minimized and muga silk yarn of October (Kotia) crop with high tenacity should be used as warp yarn in weaving

An overview of vaccine development for COVID-19

The COVID-19 pandemic continues to endanger world health and the economy. The causative SARS-CoV-2 coronavirus has a unique replication system. The end point of the COVID-19 pandemic is either herd immunity or widespread availability of an effective vaccine. Multiple candidate vaccines - peptide, virus-like particle, viral vectors (replicating and nonreplicating), nucleic acids (DNA or RNA), live attenuated virus, recombinant designed proteins and inactivated virus - are presently under various stages of expansion, and a small number of vaccine candidates have progressed into clinical phases. At the time of writing, three major pharmaceutical companies, namely Pfizer and Moderna, have their vaccines under mass production and administered to the public. This review aims to investigate the most critical vaccines developed for COVID-19 to date