Case Studies on National R&D Performance Management in the Construction Technology Sector

학위논문(박사) --서울대학교 대학원 :건설환경공학부,2010.2.Docto

Ownership of Human Biological Material - Concerning on Dead Body -

전통적인 법이론에 의하여 인간은 권리의 주체이기 때문에 인체로부터 유래한 생물학적 물질은 권리의 객체가 될 수 없다. 하지만 의학과 생명과학의 발전으로 인하여 인체로부터 유래한 생물학적 물질은 다양한 용도로 사용되고 있으며 인체로부터 유래한 생물학적 물질의 객체성 여부와 소유권 인정 여부에 대한 논의는 지속적으로 제기되고 있다.인체로부터 유래한 생물학적 물질을 법적으로 파악하는 이론은 전통적으로 자율성에 근거한 모델이었으며 현재도 그것이 가장 보편적으로 받아들여지고 있다. 하지만 자율성 모델에 의하여 인체로부터 유래한 생물학적 물질을 파악할 경우 인체로부터 유래한 생물학적 물질을 다루는 현실을 제대로 설명할 수 없을 뿐만 아니라 오히려 배분적 정의의 측면에서 볼 때 적절하지 못한 결론에 도달할 수도 있다는 의문이 제기되고 있다.인체 유래 생물학적 물질을 소유권의 객체로 파악하려는 소유권 모델은 인간의 존엄과 가치에 반하는 이론 구성이라는 의혹을 받고 있다. 하지만 소유권은 단일한 권리가 아니며 다양한 권리들의 집합체이며 그 내용이 어떻게 구성될 것인가는 객체의 특성 등을 고려하여 판단하면 될 것으로 생각된다.본 논문은 인체 유래 생물학적 물질의 소유권 전체 보다는 일단 사체로부터 유래한 물질의 소유권 인정 여부를 중점적으로 다루었다. 이를 통하여 인체 유래 생물학적 물질 전반에 대한 법이론적 고찰이 현재의 과학적 사실에 적합한 형태로 이루어지기를 기대한다. Ownership is the bundle of rights that allow a person or institute to use and control an object. As the biomedical science is advanced, we should consider whether human biological material should be recognized as property.Whether separated parts of the human body can be objects of ownership is a different issue. Many thought that separated parts of the human body could not be objects of ownership. This idea is primarily based on this thought: even if a piece of human biological material is separated from a person, it still relates to that person, and if treated as a thing, human dignity may be harmed. However, some commentators have admitted separated parts of the human body into the realm of property.Though a person owns his/her body or body parts, this does not mean that he/she can do anything he/she desires. There are many natural and social limitations to exercise the ownership of human biological material as discussed above. Human dignity is the core consideration whether or not we recognize that ownership of human biological material biomedical research and knowledge.본 논문은 미래창조과학부의 2016년 <법과학의 윤리적, 법적, 사히적 함의>연구(과제번호:2014M3A9E1070338)의 지원을 받아서 작성되었습니다

刑法上 責任能力에 관한 硏究 : 判斷基準을 中心으로

학위논문(석사)--서울大學校 大學院 :法學科 刑事法專攻,1997.Maste

Die Einwilling des Verletzten

학위논문(박사)--서울대학교 대학원 :법학과 형사법전공,1999.Docto

자녀의 스마트폰 사용 중재 사례 연구

학위논문(석사) - 한국과학기술원 : 지식서비스공학대학원, 2018.2,[iv, 72 p. :]사람의 행동 변화를 지원하는 중재서비스는 기술의 발전과 함께 다양한 형태로 발전되고 있다. 인터넷과 모바일 기술이 행동 변화 과정에 개입하는 전문가의 역할을 보완하기 위해 활용되면서, 전통적인 면대면 행동 중재 방식보다 중재서비스의 접근성이 확대되고, 중재 비용이 절감되었다. 이러한 기술 기반 중재 방식에서 더 나아가, 본 연구에서는 모바일 환경에서 사용자의 일상에 밀착된 형태로 중재서비스를 제공하는 기법 MS-MOOI(Mobile Situated Massive Open Online Intervention)를 제안한다. MS-MOOI는 MOOC 형식으로 중재 관련 정보를 제공하고, 모바일 애플리케이션으로 사용자의 일상을 모니터링하며 필요한 활동을 제시하여 행동 변화를 유도한다. 연구에서는 MS-MOOI를 적용하여 자녀에 대한 부모의 스마트폰 사용 지도 방식을 개선하기 위한 교육프로그램을 개발했고, 가정을 모집하여 프로그램을 경험한 후 평가하게 했다. 또한, 프로그램 수행 과정에서 참가자의 활동 기록, 사용자 경험, 변화된 행동 등을 탐구했다. 이를 바탕으로, 행동 변화를 지원하는 중재서비스로서의 MS-MOOI의 가능성을 제시하며, 추후 MS-MOOI의 개선을 위해 고려되어야 할 디자인 요소를 확인한다.한국과학기술원 :지식서비스공학대학원

The effect of human freeze dried corticocancellous block onlay graft on bone formation in rat calvarium

The aim of this study was to investigate the effect of an onlay graft of human freeze dried corticocancellous bone block (FDBB) on bone formation and the added effects of collagen membrane (CM) in rat calvarium. Thirty male Sprague-Dawley rats were treated with either collagen sponge (CS), FDBB or FDBB with CM. FDBBs were placed on the calvarium surface with the CM covered or not. Rats were sacrificed at 2 and 8 weeks after surgery for histologic and histomorphometric analysis. At each period, total augmented area (TA; mm2), new bone area (NB; mm2), and bone density (BD; %) were measured. In the FDBB and the FDBB/CM group, new bone formation began at the lateral and inferior margins of the grafted block and projected into the central region of the recipient-graft interface. The cancellous portion of the graft underwent increased resorption with time. FDBB showed a significant decrease in the TA between 2 and 8 weeks (p<0.05), regardless of combined use of the CM. NB significantly increased in FDBB between 2 and 8 weeks (p<0.05), and the CM showed significant additional effect on new bone formation at 8 weeks (p<0.05). BD significantly increased in FDBB between 2 and 8 weeks (p<0.05). Within the limits of the present study, it was concluded that the maintenance of volume was achieved with onlay grafting of FDBB in early healing period to show new bone apposition onto the rat calvarial surface. In addition, using of CM improved new bone formation within in the grafted area. © 2014, The Korean Tissue Engineering and Regenerative Medicine Society and Springer Science+Business Media Dordrecht

The Effects of Platelet-Rich Plasma on the Proliferation and Release of Growth Factors from Periodontal Ligament Cells

Periodontal ligament cells (PDLCs) play an important role in the regeneration of periodontium. The healing potential of PDLCs may be due to the high concentration of growth factors in platelet-rich plasma (PRP). In this study, the effects of PRP on the proliferation and activation of PDLCs and growth factor release from PDLCs were investigated. PDLCs were isolated from third molars or premolars of healthy patients. Whole blood was obtained from healthy volunteers for the preparation of activated PRP. The platelet concentration in PRP was measured and the amount of platelet-derived growth factor (PDGF)-AB, PDGF-BB, transforming growth factor-beta 1 (TGF-beta 1), and vascular endothelial growth factor (VEGF) were determined by enzyme-linked immunosorbent assay. The effects of activated PRP on PDLC proliferation, attachment, alkaline phosphatase (ALP) activity, and growth factor release were investigated. Platelet concentration was increased 5.41-fold in PRP compared to whole blood. PDGF-AB, PDGF-BB, TGF-beta 1, and VEGF were detected in PRP at concentrations of 273.38 ng/mL, 47.0 ng/mL, 168.42 ng/mL, and 510.56 pg/mL, respectively. PDLCs cultured with >= 10% PRP showed significantly increased cell proliferation and ALP activity compared to the control (p<0.05). PDLCs cultured with 10% PRP also presented higher cell attachment and increased release of TGF-beta 1 and VEGF compared to the control (p<0.05). PRP can deliver high concentrations of growth factors to a defect site to increase the proliferation, attachment, and ALP activity of PDLCs. These results suggest that PRP might effectively contribute to periodontal regeneration

로보트를 이용한 자동조립에 있어서 진동식 조립 방법에 관한 연구

학위논문(박사) - 한국과학기술원 : 생산공학과, 1989.2, [ ix, 116 p. ]Flexible assembly system utilizing an industrial robot, which is widely studied nowadays, have to mate various parts contrary to the fixed assembly system. Since the constituents of such system may have positioning uncertainties, such FMS requires programmability and adaptability to cope with various assembly environments. However, it is very difficult to obtain a complete a priori knowledge of their characteristics. In precision assembly, even small misalignment between two mating part can cause large mating force and make the assembly be impossible as a result. Although many assembly methods were investigated to overcome those problems up to now, they have still some problems: limited applications, no programmability or using high cost sensing devices. As one of the assembly method, a vibratory assembly method is considered in this thesis. A PWM controller-based pneumatic vibratory wrist is developed, which has programmability and controllability. Although the method yields improved performances, they are critically dependent upon various system parameters. This necessitates an accurate evaluation of the vibratory assembly method. The thesis is composed of three main parts. firstly, the characteristics of the vibratory wrist are investigated through a series of simulations and experiments. The vibration characteristics such as the magnitude and the trajectory can be exactly controlled by the carrier frequencies. In addition, the center position of the vibration is regulated at the desired positions due to PI controllers. Secondly, the assembly performances are investigated through a series of insertion experiments. The assembly performance is verified through chamferless peg-in-hole task. The results show that searching a hole was performed very fast without any search algorithm at almost all carrier frequency ratio. The positioning error range in which the peg can be inserted is much dependent upon the vibration magnitude. However, there is impactforces in s...한국과학기술원 : 생산공학과