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    ๊ณต๊ธฐ์—…์˜ ๋ณด์ˆ˜ ๋ณต๋ฆฌํ›„์ƒ๊ณผ ์žฌ๋ฌด๊ฑด์ „์„ฑ๊ณผ์˜ ๊ด€๊ณ„

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    ํ•™์œ„๋…ผ๋ฌธ (์„์‚ฌ)-- ์„œ์šธ๋Œ€ํ•™๊ต ํ–‰์ •๋Œ€ํ•™์› : ๊ณต๊ธฐ์—…์ •์ฑ…ํ•™๊ณผ, 2016. 8. ๊ถŒ์ผ์›….๋ณธ ์—ฐ๊ตฌ๋Š” ๊ณต๊ณต๊ธฐ๊ด€์˜ ๋ณด์ˆ˜โ€ค๋ณต๋ฆฌํ›„์ƒ๊ณผ ์žฌ๋ฌด๊ฑด์ „์„ฑ ๋ฐ ๊ฒฝ์˜์„ฑ๊ณผ ๊ฐ„์˜ ๊ด€๊ณ„๋ฅผ 2010๋…„๋ถ€ํ„ฐ 2014๋…„๊นŒ์ง€ 5๋…„๊ฐ„ 30๊ฐœ ๊ณต๊ธฐ์—…์„ ๋Œ€์ƒ์œผ๋กœ ๋ถ„์„ํ•˜์˜€๋‹ค. ์ฃผ์ธ-๋Œ€๋ฆฌ์ธ์ด๋ก  ๋ฐ ์ธ์ ์ž๋ณธ์ด๋ก ์„ ๋ฐฐ๊ฒฝ์œผ๋กœ ๋ณด์ˆ˜โ€ค๋ณต๋ฆฌํ›„์ƒ๋น„์šฉ์ด ์žฌ๋ฌด๊ฑด์ „์„ฑ ๋ฐ ๊ฒฝ์˜์„ฑ๊ณผ์— ๋ฏธ์น˜๋Š” ์˜ํ–ฅ์„ ๊ณ ์ •ํšจ๊ณผ๋ชจํ˜• ํŒจ๋„ํšŒ๊ท€๋ถ„์„์„ ํ†ตํ•˜์—ฌ ์‹ค์ฆ ๋ถ„์„ํ•˜์˜€๋‹ค. ๋ณธ ์—ฐ๊ตฌ๋Š” ๊ณต๊ธฐ์—…์˜ ๋ณด์ˆ˜โ€ค๋ณต๋ฆฌํ›„์ƒ๋น„์šฉ์— ๊ณผ๋„ํ•œ ๋Œ€๋ฆฌ์ธ๋น„์šฉ์ด ํฌํ•จ๋˜์–ด ๋™ ๋น„์šฉ์ด ์ฐฝ์ถœํ•˜๋Š” ๊ฒฝ์ œ์  ๊ฐ€์น˜๋ฅผ ์ดˆ๊ณผํ•  ๊ฒฝ์šฐ, ๊ธฐ๊ด€์˜ ์žฌ๋ฌด๊ฑด์ „์„ฑ๊ณผ ๊ฒฝ์˜์„ฑ๊ณผ๋ฅผ ์•…ํ™”์‹œํ‚ค๋Š” ์š”์ธ์ด ๋  ๊ฒƒ์œผ๋กœ ์ถ”๋ก ํ•˜์˜€๋‹ค. ์—ฐ๊ตฌ๋Œ€์ƒ ๊ธฐ๊ด€์„ ์ „์ฒด ๋ฐ ์ •๋ถ€๊ฒฝ์˜ํ‰๊ฐ€ ๊ฒฐ๊ณผ์— ๋”ฐ๋ฅธ ๋“์  ์ƒโ€คํ•˜์œ„ ๊ธฐ๊ด€์˜ ๋‘ ๊ทธ๋ฃน์œผ๋กœ ๋‚˜๋ˆ„์–ด ๋ณด์ˆ˜โ€ค๋ณต๋ฆฌํ›„์ƒ๋น„์šฉ๊ณผ ์žฌ๋ฌด๊ฑด์ „์„ฑ ๋ฐ ๊ฒฝ์˜์„ฑ๊ณผ์˜ ๊ด€๊ณ„๋ฅผ ์‹ค์ฆ ๋ถ„์„ํ•œ ๊ฒฐ๊ณผ, ์—ฐ๊ตฌ๊ฐ€์„ค์„ ๋ถˆ์ฑ„ํƒํ•˜์˜€๋‹ค. ์ „์ฒด ์ƒ˜ํ”Œ๊ณผ ๊ฒฝ์˜ํ‰๊ฐ€ ๊ฒฐ๊ณผ๊ฐ€ ์šฐ์ˆ˜ํ•œ ๊ธฐ๊ด€์˜ ์ƒ˜ํ”Œ์—์„œ ๋ณด์ˆ˜โ€ค๋ณต๋ฆฌํ›„์ƒ์ˆ˜์ค€์ด ๋†’์€ ๊ธฐ๊ด€์ด ์žฌ๋ฌด๊ฑด์ „์„ฑ์ด ์šฐ์ˆ˜ํ•œ ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ๋‹ค. ๋”ฐ๋ผ์„œ ๋†’์€ ๋ณด์ˆ˜โ€ค๋ณต๋ฆฌํ›„์ƒ๋น„ ์ˆ˜์ค€๊ณผ ๋†’์€ ์žฌ๋ฌด๊ฑด์ „์„ฑ์€ ์„œ๋กœ ์ƒ์ถฉ๋˜๋Š” ๊ฐ€์น˜๊ฐ€ ์•„๋‹˜์„ ํ™•์ธํ•˜์˜€๋‹ค. ์ฃผ์š”์–ด : ๊ณต๊ธฐ์—…, ๋ณด์ˆ˜, ๋ณต๋ฆฌํ›„์ƒ, ์žฌ๋ฌด๊ฑด์ „์„ฑ, ๋ถ€์ฑ„ ํ•™ ๋ฒˆ : 2015-24431์ œ 1 ์žฅ ์„œ ๋ก  1 ์ œ1์ ˆ ์—ฐ๊ตฌ๋ฐฐ๊ฒฝ๊ณผ ๋ชฉ์  1 ์ œ2์ ˆ ์—ฐ๊ตฌ๋Œ€์ƒ๊ณผ ๋ฐฉ๋ฒ• ๋ฐ ๋…ผ๋ฌธ์˜ ๊ตฌ์„ฑ 3 ์ œ 2 ์žฅ ๊ณต๊ณต๊ธฐ๊ด€ ๋ถ€์ฑ„ ๋ฐ ๋ณด์ˆ˜โ€ค๋ณต๋ฆฌํ›„์ƒ ํ˜„ํ™ฉ 5 ์ œ1์ ˆ ๊ณต๊ณต๊ธฐ๊ด€ ๋ถ€์ฑ„ํ˜„ํ™ฉ 5 ์ œ2์ ˆ ๊ณต๊ณต๊ธฐ๊ด€ ๋ณด์ˆ˜โ€ค๋ณต๋ฆฌํ›„์ƒ ํ˜„ํ™ฉ 5 ์ œ3์ ˆ ๊ณต๊ณต๊ธฐ๊ด€ ์ •์ƒํ™”๋Œ€์ฑ… 8 ์ œ 3 ์žฅ ์ด๋ก ์  ๋…ผ์˜ ๋ฐ ์„ ํ–‰์—ฐ๊ตฌ ๊ฒ€ํ†  10 ์ œ1์ ˆ ๋ถ€์ฑ„๊ด€๋ จ ์ด๋ก ์  ๋…ผ์˜ ๋ฐ ์„ ํ–‰์—ฐ๊ตฌ 10 ์ œ2์ ˆ ๋ณด์ˆ˜๋ณต๋ฆฌํ›„์ƒ ๊ด€๋ จ ์ด๋ก ์  ๋…ผ์˜ ๋ฐ ์„ ํ–‰์—ฐ๊ตฌ 16 ์ œ 4 ์žฅ ์—ฐ๊ตฌ์„ค๊ณ„ ๋ฐ ๋ถ„์„๋ฐฉ๋ฒ• 20 ์ œ1์ ˆ ์—ฐ๊ตฌ๋ชจํ˜• ๋ฐ ์—ฐ๊ตฌ๊ฐ€์„ค 20 ์ œ2์ ˆ ๋ณ€์ˆ˜์˜ ์ •์˜ 24 ์ œ3์ ˆ ๋ถ„์„๋Œ€์ƒ๊ณผ ๋ถ„์„๋ฐฉ๋ฒ• 29 ์ œ 5 ์žฅ ์—ฐ๊ตฌ๊ฒฐ๊ณผ 31 ์ œ1์ ˆ ๊ธฐ์ˆ ํ†ต๊ณ„๋ถ„์„ 31 ์ œ2์ ˆ ํšŒ๊ท€๋ถ„์„ 38 ์ œ 6 ์žฅ ๊ฒฐ๋ก  55 ์ œ1์ ˆ ์—ฐ๊ตฌ์˜ ๊ฒฐ๋ก  55 ์ œ2์ ˆ ์—ฐ๊ตฌ์˜ ์‹œ์‚ฌ์  ๋ฐ ํ•œ๊ณ„ 56 ์ฐธ๊ณ ๋ฌธํ—Œ 58 Abstract 60Maste

    (The) study on normal endometrial and concomitant ovarian histology of Korean women following normal menstruation

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    ์˜ํ•™๊ณผ/์„์‚ฌ[ํ•œ๊ธ€] ์ •์ƒ์ ์ธ ์›”๊ฒฝ์ฃผ๊ธฐ๋ฅผ ๊ฐ€์ง„ ์‚ฌ๋žŒ์˜ ๊ฐ ์‹œ๊ธฐ๋ณ„ ์ž๊ถ๋‚ด๋ง‰์˜ ์กฐ์ง์ƒ๊ณผ ๋‚œ์†Œ์˜ ๋ณ€ํ˜ธ๋ฅผ ์ดํ•ดํ•˜๋ฉด ์ž๊ถ๋‚ด๋ง‰ ๋˜๋Š” ๋‚œ์†Œ์˜ ๊ธฐ๋Šฅ์ ์ธ ์งˆํ™˜์„ ๊ฐ€์ง„ ํ™˜์ž๋ฅผ ์ ‘ํ•  ๋Œ€ ์–ด๋Š” ๋‹จ๊ณ„์˜ ์ด์ƒ์ธ์ง€๋ฅผ ํŒ์ •ํ•˜๋Š” ๋ฐ ํฌ๊ฒŒ ๋„์›€์ด ๋œ๋‹ค. ์ •์ƒ ์ž๊ถ๋‚ด๋ง‰ ๋ฐ ๋‚œ์†Œ์˜ ์ด๋Ÿฌํ•œ ํ‘œ์ค€์ ์ธ ์กฐ์ง์ƒ์—๋Š” ์ธ์ข… ๋˜๋Š” ํ™˜๊ฒฝ์š”์†Œ๊ฐ€ ๊ด€์—ฌํ•  ๊ฐ€๋Šฅ์„ฑ์„ ๋ฐฐ์ œํ•  ์ˆ˜ ์—†์Œ์—๋„ ๋ถˆ๊ตฌํ•˜๊ณ  ์•„์ง ํ•œ๊ตญ์ธ์„ ๋Œ€์ƒ์œผ๋กœ ํ•œ ์—ฐ๊ตฌ๊ฐ€ ๊ฑฐ์˜ ์—†๋‹ค. ๊ทธ๋Ÿฌ๋ฏ€๋กœ ์ง€๋‚œ 3๋…„๊ฐ„ ์›์ฃผ๊ธฐ๋…๋ณ‘์› ์‚ฐ๋ถ€์ธ๊ณผ ๋ฐ ๋ณ‘๋ฆฌํ•™๊ต์‹ค๊ณผ 3๋…„ 5๊ฐœ์›”๊ฐ„ ์˜๋™์„ธ๋ธŒ๋ž€์Šค๋ณ‘์› ์‚ฐ๋ถ€์ธ๊ณผ ๋ฐ ๋ณ‘๋ฆฌ๊ณผ์—์„œ ๊ฒ€์ƒ‰ํ•˜์˜€๋˜ ์ •์ƒ ์›”๊ฒฝ์ฃผ๊ธฐ๋ฅผ ์ง€๋‹Œ ๊ฐ€์ž„์—ฐ๋ น์˜ ์—ฌ์„ฑ์—์„œ ๋‚œ์†Œ ๋ฐ ์ž๊ถ๋‚ด๋ง‰์งˆํ™˜ ์ด์™ธ์˜ ์ˆ˜์ˆ ์ ์‘์ฆ์ด ์žˆ์–ด ์ž๊ถ ๋ฐ ๊ธฐ๋Šฅ์„ฑ ๋‚œํฌ๊ฐ€ ํฌํ•จ๋œ ๋‚œ์†Œ๋ฅผ ๋™์‹œ์— ์ ˆ์ œํ•œ ์˜ˆ๋“ค์„ ๋Œ€์ƒ์œผ๋กœ ์ด๋“ค์˜ ์ž๊ถ๋‚ด๋ง‰๊ณผ ๋‚œ์†Œ๊ฐ€ ์•Œ๋ ค์ง„ ์›”๊ฒฝ์ฃผ๊ธฐ์— ๋”ฐ๋ผ ์–ด๋–ค ์กฐ์ง์ƒ์„ ๋‚˜ํƒ€๋‚ด๋Š” ๊ฐ€๋ฅผ ์กฐ์‚ฌํ•œ ๋ฐ” ๋‹ค์Œ๊ณผ ๊ฐ™์€ ๊ฒฐ๋ก ์„ ์–ป์—ˆ๋‹ค. 1) ์ด 184์˜ˆ์˜ ํ•œ๊ตญ์—ฌ์„ฑ์˜ ์ •์ƒ ์›”๊ฒฝ์ฃผ๊ธฐ์— ๋”ฐ๋ฅธ ์ž๊ถ๋‚ด๋ง‰์˜ ๋ณ€ํ™”๋Š” ๊ธฐ์กด์˜ ๊ตญ๋‚ด์™ธ์˜ ๋ณด๊ณ ์™€ ๊ฑฐ์˜ ๋™์ผํ•˜์˜€๋‹ค(Noyes, 1950; ์ง€ ๋ฐ ์ตœ, 1980). 2) ์—ฐ๊ตฌ์กฐ๊ฑด์— ํ•ฉ๋‹นํ•œ ๋‚œ์†Œ๋Š” ๋ชจ๋‘ 116์˜ˆ ์˜€์œผ๋ฉฐ, ํ™ฉ์ฒดํ˜•์„ฑ์ด ๋˜๊ธฐ ์ „ ๋‹จ๊ณ„์ธ ์ „๋ฐฐ๋ž€๊ธฐ์—์„œ๋Š” ๋‚œํฌ์˜ ํ•˜๋ฃจํ•˜๋ฃจ๋ฅผ ๊ตฌ๋ณ„ํ•  ์ˆ˜ ์žˆ๋Š” ๋šœ๋ ทํ•œ ์กฐ์งํ•™์  ํŠน์ง•์„ ์ฐพ์„ ์ˆ˜ ์—†์—ˆ๋‹ค. ๋ฐฐ๋ž€์ผ๋กœ๋ถ€ํ„ฐ ์›”๊ฒฝ์ด ์‹œ์ž‘ํ•˜๊ธฐ๊นŒ์ง€์˜ ํ™ฉ์ฒด์˜ ๋ณ€ํ™”์— ์žˆ์–ด์„œ๋„ ๋•Œ์— ๋”ฐ๋ผ์„œ๋Š” ํ•˜๋ฃจํ•˜๋ฃจ๋ฅผ ๊ตฌ๋ณ„ํ•  ์ˆ˜ ์žˆ๋Š” ์กฐ์งํ•™์  ํŠน์ง•์ด ๋šœ๋ ทํ•˜์ง€ ์•Š์•˜์œผ๋‚˜ ์ž๊ถ๋‚ด๋ง‰ ์†Œ๊ฒฌ์„ ์ฐธ๊ณ ํ•˜์—ฌ ๋น„๊ต์  ์ผ๊ด€์„ฑ ์žˆ๋Š” ์†Œ๊ฒฌ์„ ๊ด€์ฐฐํ•  ์ˆ˜ ์žˆ์—ˆ์œผ๋ฉฐ ์ด๋“ค๋„ ์—ญ์‹œ ์ด๋ฏธ ๋ณด๊ณ ๋œ ๋‹ค๋ฅธ ์ €์ž๋“ค์˜ ๊ฒƒ๊ณผ ๋Œ€๋™์†Œ์ดํ•˜์˜€๋‹ค.(Brewer, 1942; Corner, 1945, 1956). 3) ๋ณด๋‹ค ๋” ์ •ํ™•ํ•œ ํ˜•ํƒœํ•™์  ํŠน์ง•์„ ์ œ์‹œํ•˜๊ธฐ ์œ„ํ•˜์—ฌ๋Š” ๋” ๋งŽ์€ ์ˆ˜์˜ ๊ฒ€์ƒ‰ ์ž๋ฃŒ์™€ ์ •ํ™•ํ•œ ๋ฐฐ๋ž€์ผ ์ธก์ •์ด ํ•„์š”ํ•˜๋‹ค๊ณ  ์‚ฌ๋ฃŒ๋˜์—ˆ๋‹ค. [์˜๋ฌธ] Normal endometrial and concomitant ovarian histology during menstrual cycle was obtained, bases on 184 normal uteri with or without ovaries including functional follicles that were removed surgically. These uteri and ovaries were selected from all the hysterectomy specimens with or without adnexa for the period of 3years and 5months at Young dong Severance Hospital and of 3years at Won ju Christian Hospital. Only those uteri that showed no gross or microscopic abnormalities except for a minimal lesions confined within the cervix were included in the study. The ovaries had to include functional follicles without pathologic lesions, and the lesions were minimal, if any. Microscopic findings of each endometrium were described according to the criteria set beforehand, and then were matches with menstrual history. The result was much the same as the previous reports by Noyes, et al.(1950) and Chi and Choi in Korea(1980). Cases selected for the histological dating of the corpus luteum were markedly limited(116 cases). Prior to ovulation, it was impossible to observe the characteristic histologic findings of the functional follicle matched with menstrual history. But each histologic finding of the corpus luteum between the day of ovulation and the standard cycle day 28 was distinguishable by its characteristic histologic findings, and the result of the histological dating of the corpus luteum was relatively corresponded to the previous report by Corner(1956). Further studies must be performed with much more specimens and with much more detail ovulation days for making a more accurate norm and for evaluating abnormal histology of the ovaries.restrictio
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