10 research outputs found

    A Study on the Strengthening Competitiveness of Korean Global Container Shipping Lines

    Get PDF
    ์ง€๋‚œ ์ˆ˜์‹ญ๋…„๊ฐ„ ํ•ด์šด ์‹œํ™ฉ ์ˆœํ™˜์˜ ๋ณ€ํ™”๋ฅผ ์‚ดํŽด๋ณด๋ฉด, ์ •๊ธฐ์„  ํ•ด์šด ์‹œํ™ฉ์€ 1980๋…„๋Œ€์— ๋“ค์–ด ํšŒ๋ณต๊ธฐ์™€ ์ •์ ๊ธฐ๋ฅผ ๊ฑฐ์ณ 1990๋…„๋Œ€์— ํ•˜๊ฐ•๊ธฐ์™€ ์ €์ ๊ธฐ๋กœ ์ ‘์–ด๋“ค๊ฒŒ ๋œ๋‹ค. ๊ทธ๋‹ค์Œ์œผ๋กœ ์™ธํ™˜์œ„๊ธฐ ์‚ฌํƒœ๊ฐ€ ํšŒ๋ณต๋˜๊ณ  ์ค‘๊ตญ์˜ ์ดˆ๊ณ ์† ์„ฑ์žฅ์œผ๋กœ ์ธํ•ด ๋‹ค์‹œ ์ •์ ๊ธฐ๋ฅผ ์ง€๋‚œ ์งํ›„ 2009๋…„์— ๋งž์ดํ•œ ์„ธ๊ณ„ ๊ฒฝ์ œ ์œ„๊ธฐ๋Š” ๋‹ค์‹œ ํ•œ๋ฒˆ ์ •๊ธฐ์„  ํ•ด์šด์‹œ์žฅ์„ ์ €์ ๊ธฐ๋กœ ๋˜๋Œ๋ ค ๋†“์•˜๋‹ค. ์ด๋Ÿฌํ•œ ๋‹จ๊ธฐ์  ์ˆœํ™˜์˜ ๊ด€์ ์—์„œ ๋ณด๋ฉด ํ˜„์žฌ๋Š” ์ €์ ๊ธฐ๋ฅผ ์ง€๋‚˜๊ณ  ์žˆ์œผ๋ฏ€๋กœ, ๊ฐ€๊นŒ์šด ๋ฏธ๋ž˜์— ๋‹ค์‹œ ํšŒ๋ณต๊ธฐ์— ์ ‘์–ด๋“ค ๊ฒƒ์ด๋ผ๋Š” ๊ฒƒ์ด ์ผ๋ฐ˜์ ์ธ ๋ถ„์„์ด๋‹ค. 1990๋…„๋ถ€ํ„ฐ 2009๋…„ ๊ฒฝ์ œ ์œ„๊ธฐ ์ „๊นŒ์ง€ ์•ฝ 20๋…„ ๋™์•ˆ ์ •๊ธฐ์„  ํ•ด์šด์˜ ์ˆ˜์š”๋Š” ์—ฐํ‰๊ท  7โˆผ10%์˜ ๊ธ‰์†ํ•œ ์„ฑ์žฅ์„ ์ง€์†ํ•ด์™”๋‹ค. 2009๋…„ ๊ฒฝ์ œ ์œ„๊ธฐ ์ด์ „์˜ ์„ฑ์žฅ๊ธฐ์— ์ •๊ธฐ์„  ํ•ด์šด๊ธฐ์—…๋“ค์ด ์ถ”์ง„ํ•œ ๊ฒฝ์˜์ „๋žต๋“ค์€ ๊ทœ๋ชจ์˜ ํ™•์ถฉ, ์–ผ๋ผ์ด์–ธ์Šค, ์„œ๋น„์Šค ์ฐจ๋ณ„ํ™”, IT ๋ฐ ํ”„๋กœ์„ธ์Šค ๊ฐœ์„ ์˜ 4๊ฐ€์ง€๋กœ ์š”์•ฝ๋  ์ˆ˜ ์žˆ๋‹ค. ์ฒซ์งธ, ์‹ ์กฐ์„  ๋ฐœ์ฃผ๋‚˜ M&A์™€ ๊ฐ™์€ ๊ทœ๋ชจ์˜ ํ™•์ถฉ์€ ๊ทœ๋ชจ์˜ ๊ฒฝ์ œ(Economy of Scale)๋ฅผ ํ†ตํ•œ ๊ฐ€๊ฒฉ ๊ฒฝ์Ÿ๋ ฅ ๊ฐ•ํ™”์— ์ฃผ์•ˆ์ ์„ ๋‘๊ณ  ์žˆ๋‹ค. ๋‘˜์งธ, ์–ผ๋ผ์ด์–ธ์Šค๋ฅผ ํ†ตํ•œ ๋„คํŠธ์›Œํฌ์™€ ์„œ๋น„์Šค์˜ ํ™•๋Œ€์ธ๋ฐ, ์ด๋Š” ํ•ญ๊ณต ์–ผ๋ผ์ด์–ธ์Šค๋ณด๋‹ค ์•ž์„œ ๋„์ž…๋œ ์ „๋žต์ด๋‹ค. ์…‹์งธ, ํ•ญ๋งŒ ํ„ฐ๋ฏธ๋„ ํˆฌ์ž๋ฅผ ํ†ตํ•œ ์„œ๋น„์Šค ์ฐจ๋ณ„ํ™”์ด๋‹ค. ์ž์‚ฌ ํ„ฐ๋ฏธ๋„ ํ™•๋ณด๋ฅผ ํ†ตํ•œ ์šด์†ก ์„œ๋น„์Šค ๊ฐœ์„  ๋ฐ ์›๊ฐ€์˜ ์ ˆ๊ฐ๊ณผ ์‚ฌ์—… ํฌํŠธํด๋ฆฌ์˜ค ํ™•๋Œ€ ๋“ฑ์˜ ๋ชฉ์ ์œผ๋กœ ์—ฌ๋Ÿฌ ํ•ด์šด ๊ธฐ์—…๋“ค์ด ์ฃผ์š” ํ•ญ๋งŒ์— ์ž์‚ฌ ํ„ฐ๋ฏธ๋„์„ ํ™•๋ณดํ•˜๊ธฐ ์‹œ์ž‘ํ•˜์˜€๋‹ค. ๋งˆ์ง€๋ง‰์œผ๋กœ ์„œ๋น„์Šค ๊ฐœ์„ ์„ ์œ„ํ•œ ํ”„๋กœ์„ธ์Šค ํ˜์‹ ๊ณผ IT ์ธํ”„๋ผ ๊ตฌ์ถ•์ด๋‹ค. ๊ธ€๋กœ๋ฒŒ ์ •๊ธฐ์„  ์„ ์‚ฌ๋“ค์€ Maersk๋ฅผ ์‹œ์ž‘์œผ๋กœ ํ•˜์—ฌ ๋Œ€๋Œ€์ ์ธ ํ”„๋กœ์„ธ์Šค ํ˜์‹ (Process Innovation) ํ”„๋กœ์ ํŠธ๋ฅผ ์ง„ํ–‰ํ•˜์˜€๋‹ค. ์ด๋ฅผ ํ†ตํ•œ ๊ณ ๊ฐ ์„œ๋น„์Šค ๊ฐœ์„ , ์ˆ˜์ต๊ด€๋ฆฌ ์‹œ์Šคํ…œ๋„์ž…, ๋น„์šฉ ์ ˆ๊ฐ์„ ํ†ตํ•œ ๊ฒฝ์Ÿ๋ ฅ ๊ฐ•ํ™” ๋ฐ ๊ฒฝ์˜ ๊ด€๋ฆฌ ์‹œ์Šคํ…œ ๋„์ž… ๋“ฑ๊ณผ ๊ฐ™์€ ๋ณ€ํ™”๋ฅผ ์‹œ๋„ํ•˜์˜€์œผ๋ฉฐ, ์ด๋ฅผ ์šด์˜ํ•˜๊ธฐ ์œ„ํ•œ IT ์ธํ”„๋ผ๋ฅผ ํ™•์ถฉํ•˜์˜€๋‹ค. ์ค‘์š”ํ•œ ๊ฒƒ์€ ์„ ๋ฐ• ์ดˆ๋Œ€ํ˜•ํ™”, ์™ธํ˜• ํ™•๋Œ€, ๊ตญ๋‚ด ํ™”์ฃผ๊ธฐ์—…๋“ค์˜ ์• ๊ตญ์‹ฌ์— ํ˜ธ์†Œํ•œ ํ™”๋ฌผ ํ™•๋ณด๋ผ๋Š” ํ˜„์žฌ๊นŒ์ง€ ์ œ์‹œ๋œ ๋‹จํŽธ์ ์ธ ์ „๋žต๋งŒ์œผ๋กœ๋Š” ์šฐ๋ฆฌ๋‚˜๋ผ ํ•ด์šด๊ธฐ์—…๋“ค์˜ ์žฌ๊ฑด๊ณผ ์ƒ์กด์— ํฐ ๋„์›€์ด ๋  ์ˆ˜ ์—†๋‹ค๋Š” ๊ฒƒ์ด๋‹ค. ๊ธ€๋กœ๋ฒŒ ํ•ด์šด๊ธฐ์—…๋“ค์˜ ์ง€๋‚œ 20๋…„์„ ํ†ตํ•˜์—ฌ ์‹œํ–‰์ฐฉ์˜ค๋ฅผ ๊ฑฐ์น˜๋ฉด์„œ ์•Œ๋ ค์ค€ ์ง€๋ฆ„๊ธธ์„ ์ž˜ ๋ถ„์„ํ•˜์—ฌ ๋ณด๊ณ  ์ƒํ™ฉ ๋ณ€ํ™”์— ๋งž์ถฐ ํ•œ๊ตญ ํ•ด์šด์ด ๋‚˜์•„๊ฐˆ ๋ฐฉํ–ฅ๊ณผ ์ „๋žต์„ ์ˆ˜๋ฆฝํ•˜๊ณ  ๋‚˜์•„๊ฐ€๋Š” ๊ฒƒ์— ์ด๋ฒˆ ๊ธ€์˜ ์˜๋ฏธ๊ฐ€ ์žˆ์„ ๊ฒƒ์œผ๋กœ ํŒ๋‹จ๋œ๋‹ค. ๋”ฐ๋ผ์„œ ๋ณธ ๋…ผ๋ฌธ์—์„œ๋Š” ๊ธ€๋กœ๋ฒŒ ์ฃผ์š” ํ•ด์šดํšŒ์‚ฌ์™€ ์šฐ๋ฆฌ๋‚˜๋ผ ์ •๊ธฐ์„ ์‚ฌ์˜ ํ˜„ํ™ฉ์„ ๋น„๊ต๋ถ„์„ํ•˜๊ณ , ์šฐ๋ฆฌ๋‚˜๋ผ ์ปจํ…Œ์ด๋„ˆ ํ•ด์šด๊ธฐ์—…์˜ ๊ฒฝ์Ÿ์ „๋žต ๋ฐฉ์•ˆ์— ๋Œ€ํ•˜์—ฌ ๋ถ„์„ํ•˜์˜€๋‹ค. ์ œ1์žฅ ์„œ ๋ก  1 ์ œ1์ ˆ ์—ฐ๊ตฌ๋ฐฐ๊ฒฝ ๋ฐ ๋ชฉ์  1 ์ œ2์ ˆ ์—ฐ๊ตฌ์˜ ๋ฐฉ๋ฒ• ๋ฐ ๊ตฌ์„ฑ 4 ์ œ2์žฅ ๊ฒฝ์Ÿ์ „๋žต์— ๊ด€ํ•œ ์ด๋ก ์  ๊ณ ์ฐฐ 5 ์ œ1์ ˆ ๊ฒฝ์Ÿ์šฐ์œ„์˜ ๊ฐœ๋… 5 1. ์ž์›๊ด€๋ฆฌ์ด๋ก  5 2. ๊ฒฝ์Ÿ์šฐ์œ„์ด๋ก  6 3. ํ•ต์‹ฌ์—ญ๋Ÿ‰์ด๋ก  7 ์ œ2์ ˆ ๊ฒฝ์Ÿ์ „๋žต์— ๊ด€ํ•œ ์—ฐ๊ตฌ๋ฐฉ๋ฒ• 7 1. PEST๋ถ„์„๋ฒ• 7 2. SWOT๋ถ„์„ 8 3. "5 Forces" ๋ถ„์„๋ชจ๋ธ 9 ์ œ3์žฅ ์„ธ๊ณ„ ์ปจํ…Œ์ด๋„ˆ ํ•ด์šด์‚ฐ์—…์˜ ํ˜„ํ™ฉ๋ถ„์„ 10 ์ œ1์ ˆ ์„ธ๊ณ„ ์ปจํ…Œ์ด๋„ˆ ํ•ด์šด์‹œ์žฅ์˜ ํ˜„ํ™ฉ 10 1. ํ•ญ๋กœ๋ณ„ ํ•ด์šด์‹œํ™ฉ 10 2. ๊ทœ๋ชจ์˜ ๊ฒฝ์ œ์™€ ๊ธ‰๊ฒฉํ•œ ์„ ๋ฐ•์˜ ๋Œ€ํ˜•ํ™” 15 3. ๊ธ€๋กœ๋ฒŒ ํ•ด์šด์‚ฌ์˜ ๋ธ”๋ก์ฒด์ธ ๊ธฐ๋ฐ˜์˜ ํ•ด์šด๋ฌผ๋ฅ˜ํ”Œ๋žซํผ ๊ฐœ๋ฐœ๊ฒฝ์Ÿ 18 4. IMO 2020 21 ์ œ2์ ˆ ํ•ด์šด ์„ ์‚ฌ๊ฐ„ ์ธ์ˆ˜ํ•ฉ๋ณ‘๊ณผ ๊ธ€๋กœ๋ฒŒ ์–ผ๋ผ์ด์–ธ์Šค์˜ ํ˜„ํ™ฉ๋ถ„์„ 22 1. ํ•ด์šด์„ ์‚ฌ๊ฐ„ ์ธ์ˆ˜ํ•ฉ๋ณ‘ 23 2. ๊ธ€๋กœ๋ฒŒ ์–ผ๋ผ์ด์–ธ์Šค ํ˜„ํ™ฉ๊ณผ ์žฌํŽธ 26 ์ œ3์ ˆ ๊ธ€๋กœ๋ฒŒ ์ปจํ…Œ์ด๋„ˆ ํ•ด์šด์‹œ์žฅ์˜ ์ „์ฒด์  ์ƒํ™ฉ 35 1. ์ฃผ์š” ์ปจํ…Œ์ด๋„ˆ ํ•ด์šด๊ธฐ์—…์˜ ๊ฒฝ์˜์ƒํ™ฉ 35 2. 2019๋…„ ๊ธ€๋กœ๋ฒŒ ์ปจํ…Œ์ด๋„ˆ ์šด์†ก์‹œ์žฅ์˜ ๋ฌผ๋™๋Ÿ‰ 36 3. 2019๋…„ ๊ธ€๋กœ๋ฒŒ ์ปจํ…Œ์ด๋„ˆ ์šด์†ก์‹œ์žฅ์˜ ์ ์žฌ๋Ÿ‰ 40 4. 2019๋…„ ๊ธ€๋กœ๋ฒŒ ์ปจํ…Œ์ด๋„ˆ ์šด์†ก์‹œ์žฅ์˜ ์šด์ž„ 42 ์ œ4์ ˆ ์ฃผ์š” ๊ธ€๋กœ๋ฒŒ ์ปจํ…Œ์ด๋„ˆ ์„ ์‚ฌ์˜ ํ˜„ํ™ฉ๊ณผ ์ „๋žต 44 1. Maersk 44 2. COSCO 47 3. ONE 51 4. ํ˜„๋Œ€์ƒ์„  54 ์ œ4์žฅ ์šฐ๋ฆฌ๋‚˜๋ผ ๊ธ€๋กœ๋ฒŒ ์ •๊ธฐ์„ ์‚ฌ์˜ ๊ฒฝ์Ÿ์ „๋žต ์ˆ˜๋ฆฝ๊ณผ ์‹คํ–‰ 58 ์ œ1์ ˆ ์ •๊ธฐ์„  ์‹œ์žฅ์˜ ๊ฒฝ์Ÿ์ „๋žต 58 ์ œ2์ ˆ ๊ตญ์ œ๋น„๊ต๋ถ„์„์„ ํ†ตํ•œ ์šฐ๋ฆฌ๋‚˜๋ผ ๊ธ€๋กœ๋ฒŒ ์ •๊ธฐ์„ ์‚ฌ์˜ ๊ฒฝ์Ÿ๋ ฅ๋ถ„์„ 60 ์ œ3์ ˆ ์šฐ๋ฆฌ๋‚˜๋ผ ๊ธ€๋กœ๋ฒŒ ์ •๊ธฐ์„ ์‚ฌ์˜ SWOT๋ถ„์„ 62 1. ๊ฐ•์ (Strengths) 62 2. ์•ฝ์ (Weaknesses) 64 3. ๊ธฐํšŒ(Opportunities) 65 4. ์œ„ํ˜‘(Threats) 69 ์ œ4์ ˆ ์šฐ๋ฆฌ๋‚˜๋ผ ๊ธ€๋กœ๋ฒŒ ์ •๊ธฐ์„ ์‚ฌ์˜ ๊ฒฝ์Ÿ์ „๋žต๊ณผ ์‹คํ–‰ ๋ฐฉ์•ˆ 71 1. ๋น„์šฉ๋ฆฌ๋”์‰ฝ ์ „๋žต(Cost Leadership Strategy): ์ €์›๊ฐ€ ์ „๋žต์˜ ์‹คํ–‰๋ฐฉ์•ˆ 73 2. ์ฐจ๋ณ„ํ™” ์ „๋žต(Differentiation Strategy): ์„œ๋น„์Šค ์ฐจ๋ณ„ํ™” ์ „๋žต์˜ ์‹คํ–‰๋ฐฉ์•ˆ 75 3. ์ง‘์ค‘ํ™” ์ „๋žต(Focus Strategy) 77 ์ œ5์žฅ ๊ฒฐ ๋ก  78 ์ œ1์ ˆ ์—ฐ๊ตฌ๊ฒฐ๊ณผ์˜ ์š”์•ฝ ๋ฐ ์‹œ์‚ฌ์  78 ์ œ2์ ˆ ์—ฐ๊ตฌ์˜ ํ•œ๊ณ„์ ๊ณผ ํ–ฅํ›„ ์—ฐ๊ตฌ๊ณผ์ œ 80Maste

    Engineering geological charcaterization of jointed rock masses and bimrock in the Yangnam basin, Korea

    No full text
    ํ•™์œ„๋…ผ๋ฌธ(๋ฐ•์‚ฌ)--์„œ์šธ๋Œ€ํ•™๊ต ๋Œ€ํ•™์› :์ง€๊ตฌํ™˜๊ฒฝ๊ณผํ•™๋ถ€,2005.Docto

    Management of Facial Nerve Schwannoma in Patients With Favorable Facial Function

    No full text
    Objective: We report six cases of facial nerve schwannomas in which surgical management allowed the preservation of facial nerve function. Specifically, this paper reports that a stripping surgery may provide favorable functional outcomes. Study Design: A retrospective review of preoperative and postoperative data for six patients with facial nerve schwannoma that had normal facial nerve function or a House-Brackmann grade II facial palsy before the surgery. Methods: Stripping surgery, which removed the schwannoma from the remaining nerve fascicle, was attempted on the six patients. Postoperative facial nerve function and imaging (magnetic resonance imaging) were evaluated. Results: Stripping surgery with gross total tumor removal of the mass was performed in four cases. In the two remaining cases, the stripping surgery was not possible, and decompression alone was performed. Favorable preservation of facial function was achieved in all six cases. Conclusion: It was possible to preserve facial function after surgery to remove facial nerve schwannoma. We suggest that stripping surgery, focused on the preservation of continuity of the facial nerve, may be attempted for facial nerve schwannoma in which favorable facial function has been preserved.ope

    Useful surgical techniques for facial nerve preservation in tumorous intra-temporal lesions

    No full text
    The management of the facial nerve in tumorous temporal lesions is particularly challenging due to its complex anatomic location and potential postoperative complications, including permanent facial paralysis. The most important concern regarding surgical treatment of a tumorous temporal lesion is the inevitable facial paralysis caused by nerve injury during the tumor removal, especially in patients with minimal to no preoperative facial nerve dysfunction. We describe successful four cases in which various surgical techniques were developed for the preservation of the facial nerve in treatment of intratemporal tumorous lesionsope

    Jugular foramen schwannoma: analysis on its origin and location.

    No full text
    OBJECTIVE: To examine the microsurgical anatomy of the jugular foramen and correlate anatomical findings to clinical manifestations of jugular foramen schwannomas concerning tumor origin and location. STUDY DESIGN: Anatomical analysis of jugular foramen was performed by dissection of 25 cadavers (50 sides). By retrospective review of 9 cases of jugular foramen schwannomas surgically treated, the origin and location of tumor were studied. SETTING: Tertiary referral center. MAIN OUTCOME MEASURES: The anatomical characteristics of jugular foramen, lower cranial nerves, and inferior petrosal sinus were correlated with the origin and growth pattern of jugular foramen schwannomas. RESULTS: The superior and inferior ganglions of the glossopharyngeal nerve and the superior ganglion of the vagus nerve were located within the jugular foramen. The superior ganglions of the glossopharyngeal and vagus nerves were located superiorly, whereas the inferior ganglion of the glossopharyngeal nerve was found inferiorly in relation to the inferior petrosal sinus orifice. In our series of 9 cases of jugular foramen schwannoma, the most common nerve of origin was the vagus nerve, followed by the glossopharyngeal nerve. CONCLUSION: The reason for the predilection of the jugular foramen schwannoma for the glossopharyngeal and vagus nerves may be associated with the presence of their ganglions within the jugular foramen. Also, the inferior petrosal sinus may act as a barrier to tumor growth, and the location of the ganglion of tumor origination within the jugular foramen in relation to the inferior petrosal sinus may be correlated to the predominant direction of tumor extension.ope

    ์ถฉ๋‚จ์ง€์—ญ ์‚ฌํšŒ์ ๊ฒฝ์ œ ํ™œ์„ฑํ™”๋ฅผ ์œ„ํ•œ ์ˆœํšŒ ํ† ๋ก ํšŒ -๊ณต์ฃผ (๊น€์ข…์ˆ˜,์ •๊ฒฝ๋ก,์กฐ์„ฑํฌ,์ด์ข…๋Œ€,์ตœ์ค€,๊น€๋ฏผ์ˆ™,๋ฐฐ์—ฐ๊ทผ)

    No full text
    N/A๏ฟญ[์ œ1์ฃผ์ œ]์ถฉ๋‚จ ์‚ฌํšŒ์ ๊ฒฝ์ œ ์ •์ฑ… ์ดํ•ด (๊น€์ข…์ˆ˜ ์ถฉ๋‚จ์‚ฌํšŒ์ ๊ฒฝ์ œ์ง€์›์„ผํ„ฐ ์ฑ…์ž„์—ฐ๊ตฌ์›) ๏ฟญ[์ œ2์ฃผ์ œ]์‚ฌํšŒ์ ๊ฒฝ์ œ์˜ ํ™œ์„ฑํ™”๋ฅผ ์œ„ํ•œ ์‚ฌํšŒ์ ๊ธฐ์—…ํ˜‘์˜ํšŒ์˜ ์—ญํ•  (์ •๊ฒฝ๋ก ์ถฉ๋‚จ์‚ฌํšŒ์ ๊ธฐ์—…ํ˜‘์˜ํšŒ ๋ถ€ํšŒ์žฅ) ๏ฟญ[์ œ3์ฃผ์ œ]์‚ฌํšŒ์ ๊ธฐ์—… ์šด์˜์‚ฌ๋ก€๋ฅผ ํ†ตํ•ด ๋ณธ ์‚ฌํšŒ์ ๊ธฐ์—… ํ™œ์„ฑํ™” ๋ฐฉ์•ˆ (์กฐ์„ฑํฌ (์‚ฌ)์ถฉ๋‚จ๊ต์œก์—ฐ๊ตฌ์†Œ ์‚ฌ๋ฌด๊ตญ์žฅ) ๏ฟญ[์‚ฌ๋ก€๋ฐœํ‘œ]์‚ฌํšŒ์  ๊ธฐ์—… '(์‚ฌ)๊ตญ์„ ๋ช…์ƒํ˜‘ํšŒ' (์ด์ข…๋Œ€ (์‚ฌ)๊ตญ์„ ๋ช…์ƒํ˜‘ํšŒ ์‚ฌ๋ฌด๊ตญ์žฅ

    Effect of ฮฒ-glucan on Growth, Feed Efficiency and Hematologic Index in Sparague-Dawley Rats

    No full text
    To investigate the toxicological effects of ฮฒ-glucan, we performed basic studying on ฮฒ-glucan in Sprague-Dawley (SD) rats. Standard endpoints in this study included mortality, clinical observations, changes of body weights, analysis on food consumption, ophthalmoscopic examination, hematologic examination, serum biochemistry,analysis of organ weights, gross anatomic pathology and histopathology. No clinical signs and mortality were observed in animals treated with beta-glucan throughout the experimental period. The average body weight of each treatment groups showed similar levels at end of experiment. There were no treatment-related changes in mortality,body weights changes, food consumption, ophthalmoscopic examination. Although there were statistically significant differences between the control and treated groups in some relative and absolute organ weights, and hematological and biochemical analysis, the data were in biologically normal ranges and did not show a dose-dependent manner. In the morphological change, hepatic tissue were not showed ballooning degeneration and irregular arrangement of hepatic cell in ฮฒ-glucan treatment groups with control group. Also, organs weights (liver, heart, kidney and stomach) and hematological indices (WBC, RBC, Hb, Hct and Platelet) did not show statistically significant differences among the experimental groups. In summary of these results, there were no changes in mortality, mean body weight, clinical signs, food consumption. There were no changes in ophthalmological examination, hematology, blood chemistry,necropsy and histopathology. In conclusion, although further investigation of glucan should be performed in the functions registered in many ancient literatures, ฮฒ-glucan is physiologically safe and may have potential as candidate food for human health.N
    corecore