77 research outputs found

    μ„œλΉ„μŠ€ ν’ˆμ§ˆ 관리에 κ΄€ν•œ 사둀연ꡬ -Life Stylist ν˜„λŒ€λ°±ν™”μ μ„ μ€‘μ‹¬μœΌλ‘œ-

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    ν˜„λŒ€λ°±ν™”μ μ€ μƒˆλ‘œμš΄ κ°€μΉ˜μ™€ λ―Έλž˜μ°½μ‘°λΌλŠ” κ²½μ˜μ΄λ… μ•„λž˜ 고객의 행볡과 주주와 κ΅¬μ„±μ›μ˜ 감동, μ‚¬νšŒμ  μ±…μž„μ˜ 이행을 κ²½μ˜ν™œλ™μ˜ κ·Όκ°„μœΌλ‘œ ν•˜μ—¬ μ‚Άμ˜ ν’μš”λ‘œμ›€μ„ λ§Œλ½ν•  수 μžˆλŠ” 21μ„ΈκΈ° μ‹ μƒν™œ λ¬Έν™” μ°½μ‘°λΌλŠ” 경영λͺ©ν‘œλ₯Ό 가지고 졜고의 μƒν’ˆ 및 μ„œλΉ„μŠ€λ‘œ 고객감동을 μ‹€ν˜„ν•¨μœΌλ‘œμ¨ μ‚¬νšŒμ—μ„œ μ‚¬λž‘ λ°›λŠ” κΈ°μ—…, 기쁨을 μ£ΌλŠ” 기업이 되고자 전사적인 μ„œλΉ„μŠ€ ν’ˆμ§ˆ 관리λ₯Ό μ§€μ†μ μœΌλ‘œ μ‹€μ‹œν•¨μœΌλ‘œμ¨ 졜고의 λͺ…ν’ˆ λ°±ν™”μ μ΄λΌλŠ” μœ„μΉ˜λ₯Ό κ³ μˆ˜ν•˜κ³  μžˆλŠ” 백화점이닀. λ³Έ μ—°κ΅¬λŠ” κ΅­λ‚΄ 백화점 사업 λΆ€λΆ„μ—μ„œ μš°μˆ˜ν•œ μ„œλΉ„μŠ€ ν’ˆμ§ˆ 사둀λ₯Ό λ³΄μ—¬μ€ŒμœΌλ‘œμ¨ λͺ…ν’ˆλ°±ν™”μ μ˜ ν™•κ³ ν•œ μœ„μΉ˜λ₯Ό μ°¨μ§€ν•˜κ³  μžˆλŠ” ν˜„λŒ€λ°±ν™”μ μ˜ μ„œλΉ„μŠ€ ν’ˆμ§ˆ μ‹œμŠ€ν…œμ— λŒ€ν•œ 사둀λ₯Ό λΆ„μ„ν•˜μ—¬ κΈ‰κ²©ν•œ κ²½μŸν™˜κ²½μ˜ 변화와 μ†ŒλΉ„μž 변화에 λŒ€μ‘ν•˜κ³  지속 κ°€λŠ₯ν•œ 경쟁λ ₯ μš°μœ„λ₯Ό μœ μ§€ν•˜κΈ° μœ„ν•΄ μ„œλΉ„μŠ€ ν’ˆμ§ˆμ„ μ–΄λ–»κ²Œ 관리해야 ν•  지에 λŒ€ν•œ μ‹œμ‚¬μ μ„ λ„μΆœν•΄λ³΄κ³ μž ν•œλ‹€

    차급별 재고쑰절 λͺ¨ν˜•μ„ ν†΅ν•œ 승용차 μˆ˜μš”μ— κ΄€ν•œ 연ꡬ

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    ν•™μœ„λ…Όλ¬Έ(석사)--μ„œμšΈλŒ€ν•™κ΅ ν™˜κ²½λŒ€ν•™μ› :ν™˜κ²½κ³„νšν•™κ³Ό κ΅ν†΅κ³„νšμ „κ³΅,1995.Maste

    Diameter control of carbon nanotubes by changing the concentration of catalytic Fe ion solutions

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    Thesis(master`s)--μ„œμšΈλŒ€ν•™κ΅ λŒ€ν•™μ› :ν™”ν•™λΆ€ 물리화학전곡,2004.Maste

    (An)Educational interpretation of John Dewey`s aesthetics

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    ν•™μœ„λ…Όλ¬Έ(박사)--μ„œμšΈλŒ€ν•™κ΅ λŒ€ν•™μ› :κ΅μœ‘ν•™κ³Ό κ΅μœ‘ν•™μ „κ³΅,2008.2.Docto

    μ‚°μ†Œ λ°œμƒ κΈ°λŠ₯μ„± ꡬ쑰체가 신생돼지 μ·Œλ„μ˜ μƒμ‘΄μœ¨κ³Ό 인슐린 λΆ„λΉ„κΈ°λŠ₯에 λ―ΈμΉ˜λŠ” 영ν–₯에 κ΄€ν•œ 연ꡬ

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    ν•™μœ„λ…Όλ¬Έ (박사)-- μ„œμšΈλŒ€ν•™κ΅ λŒ€ν•™μ› : μ˜ν•™κ³Ό, 2016. 8. μ•ˆκ·œλ¦¬.Effect of an oxygen-generating scaffold on the viability and insulin secretion function of porcine neonatal pancreatic cell clusters (NPCCs) Eun Mi Lee Major in Immunology, Department of Medicine The Graduate School Seoul National University Diabetes is a chronic metabolic disease that occurs when the body cannot produce enough insulin or cannot use insulin and is diagnosed by observing elevated levels of glucose in the blood. Diabetes therapies can be classified into oral medication, insulin injection, and pancreas or pancreatic islet transplantation. In case of final stage of diabetes, pancreatic islet transplantation would be consider as a best therapeutic strategy. Most successful diabetes therapies through intraportal islet transplantation are considered as the Edmonton protocolhowever, pancreatic islet transplantation into the hepatic venous vessels results in induction of instant blood-mediated inflammatory reaction (IBMIR). To overcome this limitation, many researchers have tried to apply an encapsulation technique for islet transplantation. It has been widely considered as a promising method for this purpose because it blocks host antibody-mediated or cellular immune responses to the donor islets. However, it is critical to maintain the survival and function of the islets because macroencapsulation reduces the oxygen supply to the islets. Therefore, in this study, to ameliorate hypoxic damage, an oxygen-generating scaffold was used to investigate whether it can improve the viability and insulin secretion function of the islets. Porcine neonatal pancreatic cell clusters (NPCCs) were isolated from ~5-day-old piglets and used after 7 days of culture for their maturation. A CCK-8 assay revealed that the PDMS-CaO2 scaffold group had higher viability than the other groups. In addition, the PDMS-CaO2 group showed reduced activity of apoptosis-related enzymes such as Caspase 3 and 7, which resulted in lower hypoxia-induced NPCCs death. Moreover, the reactive oxygen species (ROS) level in the PDMS-CaO2 group was lower than that in the control group. Since the goal of using oxygen-generating scaffolds is to provide supplemental oxygen for the NPCCs, the oxygen consumption rate (OCR) was determined in the NPCCs of the PDMS-CaO2 group. The PDMS-CaO2 group mostly showed higher OCR than the control group. The insulin secretion index of the NPCCs was higher in the PDMS-CaO2 group than in the PDMS or control group. To investigate the impact of the oxygen-generating scaffolds ex vivo, a microfluidic system was established using a BioFlux 200 instrument and microfluidic device-pump system for representing the physical conditions. After injection of the NPCCs into the PDMS or PDMS-CaO2 scaffolds, they were embedded on the hole of microfluidic device (A2) and cultured under normoxic and hypoxic conditions. The viability of the NPCCs was higher in the PDMS-CaO2 group than in the PDMS group. In addition, a biocompatibility test of the oxygen-generating scaffolds was conducted through subcutaneous implantation in mice. The scaffolds showed stability until 8 months and the immunogenicity was very low in the spleens of the recipient mice. Thus, this test can be used to confirm the viability or function of NPCCs delivered using oxygen-generating scaffolds in animal models. This study present that NPCCs encapsulated in PDMS-CaO2 scaffolds showed higher viability and insulin secretion compared to those encapsulated in PDMS scaffolds or the controls in vitro or ex vivo. In addition, a biocompatibility test of the oxygen-generating scaffold was performed by subcutaneous implantation in mice, where the scaffold showed stability until 8 months and very low immunogenicity in the spleens of the recipient mice. Thus, the oxygen-generating scaffold has potential for application in transplantation studies in the future.1. Introduction 1 1.1. Background 1 1.2. Purpose 7 2. Materials and Methods 8 3. Results 24 3.1. Oxygen-generating scaffold fabrication 24 3.2. The effect of the oxygen-generating scaffold (in vitro) 24 3.3. Biocompatibility of oxygen-generating scaffold (in vivo) 28 3.4. Establishment of microfluidic system (ex vivo) 30 3.5. The effect of the oxygen-generating scaffold (ex vivo) 32 4. Discussion 73 5. Conclusion 78 6. References 79 Abstract in Korean 91Docto

    돼지 μ¨μ½”λ°”μ΄λŸ¬μŠ€ 2ν˜•μ— κ°μ—Όλœ 자돈의 이유자돈 μ „μ‹ μ„± μ†Œλͺ¨μ„± 증후ꡰ λ°œλ³‘μ— λŒ€ν•œ λΌμ§€μ½œλ ˆλΌ λ°±μ‹ μ˜ 영ν–₯

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    ν•™μœ„λ…Όλ¬Έ(석사)--μ„œμšΈλŒ€ν•™κ΅ λŒ€ν•™μ› :μˆ˜μ˜ν•™κ³Ό μˆ˜μ˜λ³‘λ¦¬ν•™ 전곡,2006.Maste

    κΈˆμœ΅μœ„κΈ°μ—μ„œμ˜ μœ λ™μ„± 리슀크 관리와 μ‹ μš© κ³΅κΈ‰μ˜ 관계 연ꡬ

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    ν•™μœ„λ…Όλ¬Έ (석사)-- μ„œμšΈλŒ€ν•™κ΅ λŒ€ν•™μ› : κ²½μ˜ν•™κ³Ό, 2012. 2. κΉ€μ˜μ§„.λ³Έ μ—°κ΅¬μ—μ„œλŠ” κ΅­λ‚΄ κΈˆμœ΅κΈ°κ΄€ 쀑 은행듀이 μ™Έμƒμ μœΌλ‘œ λ°œμƒν•œ μœ λ™μ„± 쇼크에 μ§λ©΄ν•˜μ˜€μ„ λ•Œ μœ λ™μ„± 리슀크λ₯Ό κ΄€λ¦¬ν•˜κΈ° μœ„ν•΄ μ–΄λ–»κ²Œ λŒ€μ‘ν•˜λŠ”μ§€λ₯Ό λΆ„μ„ν•œλ‹€. κ°œλ³„ μ€ν–‰μ˜ μœ λ™μ„± 리슀크 λ…ΈμΆœ 정도에 따라 μžμ‚°μ˜ 보유 ꡬ성을 μ–΄λ–»κ²Œ μ‘°μ •ν•˜λŠ”μ§€, λ™μ‹œμ— μ‹ μš© κ³΅κΈ‰μ˜ 증감에 μ–΄λ–€ 영ν–₯을 λ―ΈμΉ˜λŠ”μ§€ κ΄€μ°°ν•œ κ²°κ³Ό 은행듀은 λ¦¬μŠ€ν¬μ— 많이 λ…ΈμΆœλ˜μ–΄ μžˆμ„μˆ˜λ‘ 내뢀적 μœ λ™μ„±μ„ μŒ“κΈ° μœ„ν•΄ λŒ€μΆœκ³Ό 약정을 κ°μΆ•ν•˜λŠ” 것을 ν™•μΈν•˜μ˜€λ‹€. 이에 따라 μ‹œμ€‘μ—λŠ” μ‹ μš© 곡급, 즉 μœ λ™μ„± 곡급이 μ›ν™œν•˜μ§€ μ•Šκ²Œ λ˜μ–΄ μ •λΆ€μ˜ μœ λ™μ„± ν™•λŒ€ λ…Έλ ₯이 ν¬μ„λ˜λŠ” 뢀뢄이 μžˆμŒμ„ κ΄€μ°°ν•˜μ˜€λ‹€.This study analyzes how Korean banking institutions managed their liquidity risk exposure in the face of liquidity shock in the fourth quarter of 2008. I confirm that they adjusted holding of asset portfolio regarding liquid asset to build up liquidity buffer which resulted in the contraction of loans and credit supply. This result implicates that there might be a possibility that banking institutions liquidity risk management leads to an ineffective liquidity distribution against governments monetary policy in the financial crisis.Maste

    歷史-ι€Έθ©±ηš„ 方法에 μ˜ν•œ η§‘ε­Έζ•Žθ‚²εŽŸη†μ˜ 瑏穢

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    ν•™μœ„λ…Όλ¬Έ(석사)--μ„œμšΈε€§ε­Έζ ‘ 倧學陒 :ζ•Žθ‚²ε­Έη§‘ ζ•Žθ‚²ε­Έε°ˆζ”»,1998.Maste
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