74 research outputs found

    ์ž„์› ์—ฐ๋ด‰ ๊ณต๊ฐœ ๋ฒ•์ด ๊ธฐ์—…์˜ ์„ฑ๊ณผ์™€ ์—ฐ๋ด‰ ์ˆ˜์ค€ ๋ณ€ํ™”์— ๋ฏธ์น˜๋Š” ์˜ํ–ฅ

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    ํ•™์œ„๋…ผ๋ฌธ (์„์‚ฌ) -- ์„œ์šธ๋Œ€ํ•™๊ต ๋Œ€ํ•™์› : ๊ฒฝ์˜๋Œ€ํ•™ ๊ฒฝ์˜ํ•™๊ณผ, 2020. 8. ์ด๊ด€ํœ˜.The 2013 FISCMA (Financial Investment Services and Capital Markets Act) in Korea required firms to disclose individual pay information of executives receiving more than 500 million KRW. Using a large panel data of 1,341 unique firms in Korea over the 2011-2016 period, this paper investigates whether the amended disclosure law has affected firms executive compensation level, firm performance and pay-performance sensitivity. Using a difference-in-differences regression analysis, I find that executive compensation increases in the bottom ranked group (bottom 30%) firms and decreases in the top ranked group (top 30%) firms, where group rankings are based on the level of average executive compensation in the pre-law period. In addition, while firm performance of the bottom ranked group firms increased, firm performance of the top ranked group firms decreased following the passage of the FISCMA. The results are similar for payโ€“performance sensitivity. The academic literature on the determinants of executive pay has been divided between two contrasting viewpoints: managerial entrenchment and tournament theory. Overall, the results of this paper supports the latter view. This paper examines a positive correlation between the change in executive compensation and firm performance in both ranked firm groups, which identifies that the level of compensation packages in Korea reflects the tournament theory.2013๋…„์— ์ƒˆ๋กญ๊ฒŒ ๊ฐœ์ •๋œ ์ž๋ณธ์‹œ์žฅ๋ฒ•์€ ์ƒ์žฅ ๊ธฐ์—… ๋“ฑ๊ธฐ ์ž„์›์ค‘ 5์–ต ์ด์ƒ์˜ ๋ณด์ˆ˜๋ฅผ ์ง€๊ธ‰๋ฐ›๋Š” ๊ฒฝ์˜์ง„์— ๋Œ€ํ•ด ๊ฐœ์ธ ๋ณด์ˆ˜ ์ •๋ณด๋ฅผ ๊ณต๊ฐœํ•˜๋„๋ก ์š”๊ตฌํ–ˆ๋‹ค. ํ•œ๊ตญ์˜ ์ƒ์žฅ ๊ธฐ์—… 1,341๊ฐœ๋ฅผ 2011๋…„๋ถ€ํ„ฐ 2016๋…„๊นŒ์ง€ ๋ถ„์„ํ•œ ๊ฒฐ๊ณผ, ๋ฒ• ๊ฐœ์ • ์ด์ „์˜ ์—ฐ๋ด‰์ˆ˜์ค€์ด ์ƒ์œ„ 30%์ธ ๊ธฐ์—…์€ ํ‰๊ท  ์ž„์› ์—ฐ๋ด‰์ด ์ค„์–ด๋“ค๊ณ  ๊ธฐ์—… ๊ฐ€์น˜ ๋˜ํ•œ ์ค„์–ด๋“œ๋Š” ๊ฒฐ๊ณผ๋ฅผ ๋ณด์˜€๋‹ค. ๋ฐ˜๋Œ€๋กœ ํ•˜์œ„ 30%์ธ ๊ธฐ์—…์€ ํ‰๊ท  ์ž„์› ์—ฐ๋ด‰์ด ์ฆ๊ฐ€ํ•˜๊ณ  ๊ธฐ์—… ๊ฐ€์น˜ ๋˜ํ•œ ์ฆ๊ฐ€ํ•˜๋Š” ๊ฒฐ๊ณผ๋ฅผ ๋ณด์˜€๋‹ค. ๊ฒฝ์˜์ง„ ๋ณด์ˆ˜์— ๊ด€๋ จํ•ด์„œ ์„ ํ–‰์—ฐ๊ตฌ๋Š” ๋‘ ๊ฐ€์ง€์˜ ๋ฐ˜๋Œ€๋˜๋Š” ์‹œ์‚ฌ์ ์„ ์ œ๊ณตํ•œ๋‹ค. ์ง€๋Œ€ ์ถ”๊ตฌ ๊ฐ€์„ค์€ ๊ฒฝ์˜์ž๊ฐ€ ์„ฑ๊ณผ์— ๋น„ํ•ด ๊ณผํ•œ ์—ฐ๋ด‰์„ ๋ฐ›๋Š” ๋‹ค๋Š” ๊ฐ€์„ค์ด๊ณ  ํ† ๋„ˆ๋จผํŠธ ์ด๋ก ์€ ๊ฒฝ์˜์ž์˜ ๋ณด์ˆ˜๊ฐ€ ๊ทธ ์„ฑ๊ณผ๋ฅผ ์ •ํ™•ํ•˜๊ฒŒ ๋ฐ˜์˜ํ•˜๊ณ  ์žˆ๋‹ค๋Š” ๊ฐ€์„ค์ด๋‹ค. ์„ ํ–‰์—ฐ๊ตฌ์—์„œ๋Š” ์—ฐ๋ด‰ ์ˆ˜์ค€์˜ ๋ณ€ํ™”์™€ ๊ธฐ์—…๊ฐ€์น˜์˜ ๋ณ€ํ™”๊ฐ€ ์–‘(+)์˜ ์ƒ๊ด€๊ด€๊ณ„๋ฅผ ๊ฐ€์ง€๋ฉด ํ† ๋„ˆ๋จผํŠธ ์ด๋ก , ์Œ(-)์˜ ์ƒ๊ด€๊ด€๊ณ„๋ฅผ ๊ฐ€์ง€๋ฉด ์ง€๋Œ€์ถ”๊ตฌ ๊ฐ€์„ค์„ ์ง€์ง€ํ•œ๋‹ค๊ณ  ์ฃผ์žฅํ•œ๋‹ค. ๊ฒฐ๊ณผ์ ์œผ๋กœ ์ด ๋…ผ๋ฌธ์€ ํ•œ๊ตญ์˜ ์ž„์› ์—ฐ๋ด‰ ์ˆ˜์ค€์ด ํ† ๋„ˆ๋จผํŠธ ์ด๋ก ์„ ์ง€์ง€ ํ•˜๊ณ  ์žˆ๋‹ค๋Š” ๊ฒฐ๊ณผ๋ฅผ ๋‚˜ํƒ€๋ƒˆ๋‹ค. ์ด๋Ÿฌํ•œ ๊ฒฐ๊ณผ๋Š” ๊ธฐ์—…๋“ค์ด ๋ฐ›๋Š” ์ •์น˜์  ๋ถ€๋‹ด์—์„œ ๋‚˜์˜จ๋‹ค๋Š” ์ ์„ ์‹œ์‚ฌํ•œ๋‹ค.1. Introduction 7 2. Literature Review 15 3.1 Sample Construction 19 3.2 Research Specification 21 3.3 Empirical Model 23 4. Empirical Results 27 5. Political Pressure 37 6. Conclusion and Discussion 40 7. References 42 Abstract in Korean 46 Table 1 48 Table 2 49 Table 3 50 Table 4 52 Table 5 54 Table 6 56 Table 7 57 Table 8 59Maste

    A case of Long QT syndrome type 3 aggravated by beta-blockers and alleviated by mexiletine: the role of epinephrine provocation test.

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    Long QT syndrome (LQTs) is an uncommon genetic disease causing sudden cardiac death with Torsade de Pointes (TdP). The first line drug treatment has been known to be ฮฒ-blocker. We encountered a 15-year-old female student with LQTs who had prolonged QTc and multiple episodes of syncope or agonal respiration during sleep. Although her T wave morphology in surface electrocardiography resembled LQTs type 1, her clinical presentation was unusual. During the epinephrine test, TdP was aggravated during ฮฒ-blocker medication, but alleviated by sodium channel blocker (mexiletine). Therefore, she underwent implantable cardioverter defibrillator implantation.ope

    Island Biogeography of the South Korean Coleoptera

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    ํ•™์œ„๋…ผ๋ฌธ (์„์‚ฌ)-- ์„œ์šธ๋Œ€ํ•™๊ต ๋Œ€ํ•™์› : ์‚ฌํšŒ๊ณผํ•™๋Œ€ํ•™ ์ง€๋ฆฌํ•™๊ณผ, 2018. 2. ๋ฐ•์ •์žฌ.Since Island Biogeography that physical environment of islands such as island size or island distance affects biodiversity of them come to the fore, many biogeographers have tried to apply the Island Biogeographic rules to several isolated environments. Besides physical environment, however, human disturbance can also affect insular biota if island is not far from mainland and has undergone human disturbance, such as many South Korean islands. In this research, therefore, I comprehended distribution pattern of the South Korean insular Coleoptera and calculated the effect of the relationship between physical environment of islands and species diversity of Coleoptera. I also speculated the specific mechanism of distribution pattern of Coleoptera through collecting samples and testing the hypothesis. Nestedness analysis result showed high nestedness value of South Korean islands for Coleoptera species and the possibility of geographical region of Coleopetran type species. The west coast generally tends to show higher nestedness than the southeast coast so that the west coast seems that undergoes less outside disturbance (human disturbance) such as invasive species from Korean peninsula. Island size was directly proportional to species diversity. However, it was also inversely proportional in big inhabited islands. It is because the islands can support larger human population and undergo severe and continuous human disturbance. Island distance was not correlated with species diversity. However, island distance was directly proportional to the number of macropterous species in the high-nestedness regions. It suggests that macropterous species have advantage over brachypterous species in terms of reaching far islands and colonizing on their own in case of less outside disturbance. To test the difference of distribution of Coleoptera with different wing length, four islands around Boryeong city in Chungcheongnamdo province were surveyed. 755 samples were collected using pitfall-trap and sweeping and identified. Identification result showed the tendency that dominance index was inversely proportional to island distance and the rate of macropterous species. It may be originated from the characteristic of macropterous species such as slow colonization and fewer individuals in restricted area. Therefore, the difference of dispersal ability with wing length may affect species composition of islands. In this research, I calculated and speculated the effect size of classical Island Biogeographic theory and human disturbance in South Korean islands, and also found distribution pattern and the mechanism of the South Korean Coleoptera. This research can be used as base data when predicting species composition and species diversity of uninvestigated islands.Chapter 1. Introduction 1 1.1. Study Background 1 1.2. Regional and Temporal Settings: Sapsido, Hodo, Nokdo and Oeyondo on the West Coast of South Korea 5 1.3. Research Purpose and Structure 9 Chapter 2. Literature Review 10 2.1. Introduction to Coleoptera 10 2.2. Studies on Island-Biogeographic Approach in South Korea and Abroad 13 Chapter 3. Methodology 15 3.1. Coleoptera sampling 15 3.2. Identification 17 3.3. Data analysis 18 Chapter 4. Research Results and Analysis 26 4.1. Identification Results 26 4.2. Ecological indices results 31 4.3. Nestedness temperature results 33 Chapter 5. Discussion 34 5.1. The Characters of Insular Coleopteran Communities of Study Area 34 5.2. Distributional Characteristics of South Korean Insular Coleopteran species 34 Chapter 6. Conclusion 49 Bibliography 52 APPENDIX 57 Appendix 1. The set-up time and location of pit-fall trap 57 Appendix 2. Calculated nestedness temperature for each site 59 Appendix 3. Calculated nestedness temperature for each species 62 Appendix 4. Multicolinearity between island size and island distance 66 Appendix 5. Difference between rate of increase of the number of Coleoptera species in relation to island size 67 ๊ตญ ๋ฌธ ์ดˆ ๋ก 70Maste

    Electroanatomical characteristics of idiopathic left ventricular tachycardia and optimal ablation target during sinus rhythm: significance of preferential conduction through Purkinje fibers

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    PURPOSE: We hypothesized that Purkinje potential and their preferential conduction to the left ventricle (LV) posteroseptum during sinus rhythm (SR) are part of reentrant circuits of idiopathic left ventricular tachycardia (ILVT) and reentry anchors to papillary muscle. MATERIALS AND METHODS: In 14 patients with ILVT (11 men, mean age 31.5ยฑ11.1 years), we compared Purkinje potential and preferential conduction during SR with VT by non-contact mapping (NCM). If clear Purkinje potential(SR) was observed in the LV posteroseptum and the earliest activation site (EA) of preferential conduction at SR (EA(SR)) was well matched with that of VT (EA(VT)), EA(SR) was targeted for radiofrequency catheter ablation (RFCA). Also, the anatomical locations of successful ablation sites were evaluated by echocardiography in five additional patients. RESULTS: 1) All induced VTs exhibited clear Purkinje potential(VT) and preferential conduction in the LV posteroseptum. The Purkinje potential(VT) and EA(VT) was within 5.8ยฑ8.2 mm of EA(SR). However, the breakout sites of VT were separated by 30.2ยฑ12.6 mm from EA(VT) to the apical side. 2) Purkinje potential(SR) demonstrated a reversed polarity to Purkinje potential(VT), and the interval of Purkinje potential(SR)-QRS was longer than the interval of Purkinje potential(VT)-QRS (p<0.02) 3) RFCA targeting EA(SR) eliminated VT in all patients without recurrence within 23.3ยฑ7.5 months, and the successful ablation site was discovered at the base of papillary muscle in the five additional (100%) patients. CONCLUSION: NCM-guided localization of EA(SR) with Purkinje potential(SR) matches well with EA(VT) with Purkinje potential(VT) and provides an effective target for RFCA, potentially at the base of papillary muscle in patients with ILVT.ope

    Comparison of optical coherence tomographic assessment between first- and second-generation drug-eluting stents

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    PURPOSE: There is a lack of sufficient data in comparison of optical coherence tomographic (OCT) findings between first- and second-generation drug-eluting stents (DES). Compared to first-generation (i.e., sirolimus- or paclitaxel-eluting stents), second-generation DESs (i.e., everolimus- or biolinx-based zotarolimus-eluting stents) might have more favorable neointimal coverage. MATERIALS AND METHODS: Follow-up OCT findings of 103 patients (119 lesions) treated with second- generation DESs were compared with those of 139 patients (149 lesions) treated with first-generation DESs. The percentage of uncovered or malapposed struts, calculated as the ratio of uncovered or malapposed struts to total struts in all OCT cross-sections, respectively, was compared between the two groups. RESULTS: Both DES groups showed similar suppression of neointimal hyperplasia (NIH) on OCT (mean NIH cross-sectional area; second- vs. first-generation=1.1ยฑ0.5 versus 1.2ยฑ1.0 mmยฒ, respectively, p=0.547). However, the percentage of uncovered struts of second-generation DESs was significantly smaller than that of first-generation DESs (3.8ยฑ4.8% vs.7.5ยฑ11.1%, respectively, p<0.001). The percentage of malapposed struts was also significantly smaller in second-generation DESs than in first-generation DESs (0.4ยฑ1.6% vs.1.4ยฑ3.7%, respectively, p=0.005). In addition, intra- stent thrombi were less frequently detected in second-generations DESs than in first-generation DESs (8% vs. 20%, respectively, p=0.004). CONCLUSION: This follow-up OCT study showed that second-generation DESs characteristically had greater neointimal coverage than first-generation DESs.ope

    A Thin Left Atrial Antral Wall Around the Pulmonary Vein Reflects Structural Remodeling by Atrial Fibrillation and is Associated with Stroke

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    PURPOSE: Circumferential pulmonary (PV) vein isolation (CPVI) is the most important treatment strategy for atrial fibrillation (AF). While understanding left atrial wall thickness around PVs (PVWT) prior to catheter ablation is important, its clinical implications are not known. This study aimed to evaluate PVWT characteristics according to underlying disease and to identify associations between PVWT and reconnections of PV potentials (PVPs) in redo ablation. MATERIALS AND METHODS: In 28 patients who underwent redo-AF ablation, PVWT and reconnected PVPs were evaluated at 12 sites (1-12 o'clock) around each PV. Clinical characteristics including stroke and CHAโ‚‚DSโ‚‚-VASc scores were analyzed according to the PVWT. RESULTS: The PVWT was thicker in males than females (p0.6 mm predicted PV reconnections with a sensitivity of 76.7% and specificity of 52.2% with an area under the curve of 0.695. CONCLUSION: Thick PVWs were associated with diabetes and heart failure, and also showed significant inverse correlations with stroke and the CHAโ‚‚DSโ‚‚-VASc score. Thick PVWs were associated with reconnected PVPs after the CPVI, which were related to AF recurrence.ope

    Prolonged PR Interval Predicts Clinical Recurrence of Atrial Fibrillation After Catheter Ablation

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    BACKGROUND: A prolonged PR interval is known to be a poor prognostic factor in cardiovascular disease. The aim of this study was to investigate the association between PR interval and clinical outcome in patients undergoing radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF). METHODS AND RESULTS: We prospectively included 576 patients with AF (75.5% male, 57.8ยฑ11.6 years old, 68.8% paroxysmal AF) who underwent RFCA. We analyzed preprocedural sinus rhythm ECGs obtained in the absence of antiarrhythmic drug, and all enrolled patients were categorized into 4 groups based on the quartile values of the PR interval (166, 182, and 202 ms), and were analyzed according to the left atrium (LA) volume (CT; Computed tomography), LA voltage (NavX), and clinical outcome of AF ablation. Based on quartile value of PR interval, the highest quartile of PR interval (Q4; PR โ‰ฅ202 ms) was oldest (P<0.001), and most likely to have persistent AF (P<0.001) and hypertension (P=0.013) compared with the other groups. However, there was no significant difference in LA conduction velocity and atrial effective refractory period. Q4 had the greatest LA dimension (P<0.001) and volume index (P<0.001), and lowest LA appendage-emptying velocity (P<0.032) and LA voltage (P<0.001) compared with the others. For 13.1ยฑ7.5 months, the classification based on the PR interval was a significant predictor of AF recurrence after RFCA of AF (HR=1.969, 95% CI 1.343 to 2.886, P=0.001). CONCLUSIONS: The PR interval was closely associated with advanced LA remodeling due to AF, and had a noninvasive significant predictive value of clinical recurrence of AF after RFCA.ope

    Clinical Significance of Additional Ablation of Atrial Premature Beats after Catheter Ablation for Atrial Fibrillation

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    PURPOSE: The clinical significance of post-procedural atrial premature beats immediately after catheter ablation for atrial fibrillation (AF) has not been clearly determined. We hypothesized that the provocation of immediate recurrence of atrial premature beats (IRAPB) and additional ablation improves the clinical outcome of AF ablation. MATERIALS AND METHODS: We enrolled 200 patients with AF (76.5% males; 57.4ยฑ11.1 years old; 64.3% paroxysmal AF) who underwent catheter ablation. Post-procedure IRAPB was defined as frequent atrial premature beats (โ‰ฅ6/min) under isoproterenol infusion (5 ฮผg/min), monitored for 10 min after internal cardioversion, and we ablated mappable IRAPBs. Post-procedural IRAPB provocations were conducted in 100 patients. We compared the patients who showed IRAPB with those who did not. We also compared the IRAPB provocation group with 100 age-, sex-, and AF-type-matched patients who completed ablation without provocation (No-Test group). RESULTS: 1) Among the post-procedural IRAPB provocation group, 33% showed IRAPB and required additional ablation with a longer procedure time (p=0.001) than those without IRAPB, without increasing the complication rate. 2) During 18.0ยฑ6.6 months of follow-up, the patients who showed IRAPB had a worse clinical recurrence rate than those who did not (27.3% vs. 9.0%; p=0.016), in spite of additional IRAPB ablation. 3) However, the clinical recurrence rate was significantly lower in the IRAPB provocation group (15.0%) than in the No-Test group (28.0%; p=0.025) without lengthening of the procedure time or raising complication rate. CONCLUSION: The presence of post-procedural IRAPB was associated with a higher recurrence rate after AF ablation. However, IRAPB provocation and additional ablation might facilitate a better clinical outcome. A further prospective randomized study is warranted.ope

    Endoscopic Treatment of a Pediatric Patient with Acute Pancreatitis Caused by Anomalous Union of Pancreaticobiliary Duct Combined with Incomplete Pancreatic Divisum

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    The most common causes of acute pancreatitis are microlithiasis and alcohol. In pediatrics, anomalies in pancreaticobiliary system should be considered as possible causes. Among many anomalies, pancreas divisum associated with anomalous pancreaticobiliary ductal union (APBDU) is very rare. APBDU is associated with acute pancreatitis, choledochal cyst, and gallbladder cancer. Pancreas divisum is also a well known cause of acute recurrent pancreatitis. In adult cases with such conditions, the role of endoscopic management including sphincterotomy or stenting through the Santorini duct is well documented. However, it is still controversial to perform endoscopic retrograde cholangiopancreatography in pediatrics. Herein, we experienced a case of 4 year 7 month old female patient suffered from recurrent attacks of acute pancreatitis, which were caused by APBDU and incomplete pancreas divisum. She was treated by endoscopic sphincteretomy of both openings to the Santorini`s and Wirsung`s ducts. Thus, we report this interesting case with literature review.ope

    Low Left Atrial Compliance Contributes to the Clinical Recurrence of Atrial Fibrillation after Catheter Ablation in Patients with Structurally and Functionally Normal Heart

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    Stiff left atrial (LA) syndrome was initially reported in post-cardiac surgery patients and known to be associated with low LA compliance. We investigated the physiological and clinical implications of LA compliance by estimating LA pulse pressure (LApp) among patients with atrial fibrillation (AF) and structurally and functionally normal heart. Among 1038 consecutive patients with LA pressure measurements before AF ablation, we included 334 patients with structurally and functionally normal heart (81.7% male, 54.1ยฑ10.6 years, 77.0% paroxysmal AF) after excluding those with hypertension, diabetes, and previous ablation or cardiac surgery. We measured LApp (peak-nadir LA pressure) at the beginning of the ablation procedure and compared the values with clinical parameters and the AF recurrence rate. AF patients with normal heart were younger and more frequently male and had paroxysmal AF, a lower body mass index, and a lower LApp compared to others (all p<0.05). Based on the median value, the low LA compliance group (LAppโ‰ฅ13 mmHg) had a smaller LA volume index and lower LA voltage (all p<0.05) compared to the high LA compliance group. During a mean follow-up of 16.7ยฑ11.8 months, low LA compliance was independently associated with two fold-higher risk of clinical AF recurrence (HR:2.202; 95%CI:1.077-4.503; p = 0.031). Low LA compliance, as determined by an elevated LApp, was associated with a smaller LA volume index and lower LA voltage and independently associated with higher clinical recurrence after catheter ablation in AF patients with structurally and functionally normal heart.ope
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