7 research outputs found

    Development and Evaluation of a Creative Problem Solving Program for Cyberbullying Prevention

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    λ³Έ μ—°κ΅¬λŠ” 창의적 λ¬Έμ œν•΄κ²°λ°©λ²•μ„ ν™œμš©ν•œ μ‚¬μ΄λ²„λΆˆλ§ 예방ꡐ윑 ν”„λ‘œκ·Έλž¨μ„ κ°œλ°œν•˜κ³  개발된 ν”„λ‘œκ·Έλž¨μ˜ 효과λ₯Ό ν™•μΈν•˜κΈ° μœ„ν•˜μ—¬ μ΄ˆλ“±ν•™κ΅ ν˜„μž₯에 μ μš©ν•˜μ—¬ 초기 μ²­μ†Œλ…„μ˜ μ‚¬μ΄λ²„λΆˆλ§ κ²½ν—˜, μ‚¬μ΄λ²„λΆˆλ§ νƒœλ„, 창의적 λ¬Έμ œν•΄κ²°μ— λ―ΈμΉ˜λŠ” νš¨κ³Όμ— λŒ€ν•΄μ„œ μ‚΄νŽ΄λ³΄κ³ μž ν•˜μ˜€λ‹€. λ³Έ μ—°κ΅¬μ—μ„œλŠ” Treffinger, Isaksen와 Dorval(2000)의 창의적 λ¬Έμ œν•΄κ²°κ³Όμ •μ— κ·Όκ±°ν•˜μ—¬ 창의적 λ¬Έμ œν•΄κ²°λ°©λ²•μ„ ν™œμš©ν•œ μ‚¬μ΄λ²„λΆˆλ§ 예방ꡐ윑 ν”„λ‘œκ·Έλž¨μ„ κ°œλ°œν•˜μ˜€λ‹€. 연ꡬ μ°Έμ—¬μžλŠ” 경기도에 μ†Œμž¬ν•œ μ΄ˆλ“±ν•™κ΅ 5ν•™λ…„ 학생 52λͺ…이닀(μ‹€ν—˜μ§‘λ‹¨: 25λͺ…, 비ꡐ집단: 27λͺ…). λ³Έ μ—°κ΅¬μ—μ„œλŠ” μ‹€ν—˜μ§‘λ‹¨μ— μ†ν•˜λŠ” μ²­μ†Œλ…„λ“€μ—κ²Œ 4μ£Όκ°„ 8μ°¨μ‹œλ‘œ κ΅¬μ„±λœ ν”„λ‘œκ·Έλž¨μ„ μ‹œν–‰ν•˜μ˜€μœΌλ©°, 같은 μ‹œκΈ° 비ꡐ집단에 μ†ν•˜λŠ” μ²­μ†Œλ…„μ—κ²ŒλŠ” 1νšŒμ„± 정보전달식 μ˜ˆλ°©κ΅μœ‘μ„ μ‹€μ‹œν•˜μ˜€λ‹€. ν”„λ‘œκ·Έλž¨ μ‹€ν–‰ μ „Β·ν›„μ˜ 차이λ₯Ό λΉ„κ΅ν•˜κΈ° μœ„ν•˜μ—¬ λ³Έ μ—°κ΅¬μ—μ„œλŠ” μ‚¬μ΄λ²„λΆˆλ§ κ²½ν—˜, μ‚¬μ΄λ²„λΆˆλ§ νƒœλ„, λŒ€μΈκ΄€κ³„ λ¬Έμ œν•΄κ²°κ³Ό 창의적 λ¬Έμ œν•΄κ²° 척도λ₯Ό ν™œμš©ν•˜μ˜€λ‹€. 연ꡬ κ²°κ³Ό, μ‚¬μ΄λ²„λΆˆλ§λ°©κ΄€ 및 λ°©μ–΄ 행동, μ‚¬μ΄λ²„λΆˆλ§ νƒœλ„, 창의적 λ¬Έμ œν•΄κ²°, λŒ€μΈ λ¬Έμ œν•΄κ²°μ΄ ν–₯μƒλœ 것을 μ•Œ 수 μžˆμ—ˆλ‹€. μ‹€ν—˜μ§‘λ‹¨κ³Ό 비ꡐ집단을 λΉ„κ΅ν•˜μ˜€μ„ λ•Œμ—λ„ μ‚¬μ΄λ²„λΆˆλ§ λ°©κ΄€ 및 λ°©μ–΄ 행동, μ‚¬μ΄λ²„λΆˆλ§ νƒœλ„, λŒ€μΈ λ¬Έμ œν•΄κ²°μ—μ„œ μœ μ˜ν•œ 차이λ₯Ό λ³΄μ΄λŠ” 것을 확인할 수 μžˆμ—ˆλ‹€. 이λ₯Ό ν†΅ν•˜μ—¬ 창의적 λ¬Έμ œν•΄κ²°λ°©λ²•μ„ ν™œμš©ν•œ μ‚¬μ΄λ²„λΆˆλ§ 예방ꡐ윑 ν”„λ‘œκ·Έλž¨μ΄ μ²­μ†Œλ…„μ˜ μ‚¬μ΄λ²„λΆˆλ§ μ˜ˆλ°©μ— 효과적일 뿐만 μ•„λ‹ˆλΌ λ¬Έμ œν•΄κ²°μ„μ¦μ§„μ‹œν‚€λŠ”λ°λ„ 도움이 됨을 μ•Œ 수 μžˆμ—ˆλ‹€.N

    ν…”λ‘œλ¨ΈλΌμ œ 유래 νŽ©νƒ€μ΄λ“œμ˜ μ’…μ–‘ μ–΅μ œ νš¨κ³Όμ— κ΄€ν•œ 연ꡬ

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    ν•™μœ„λ…Όλ¬Έ (박사)-- μ„œμšΈλŒ€ν•™κ΅ λŒ€ν•™μ› : ν˜‘λ™κ³Όμ • 쒅양생물학전곡, 2015. 8. κΉ€λ²”μ€€.Heat shock proteins (HSPs) are molecular chaperones that have critical roles in maintaining protein homeostasisthey are critical for cell survival especially under stresses such as hypoxia. HSPs, particularly HSP90 and HSP70, are highly expressed in a wide range of tumors. The expression of several HSPs has been shown to be correlated with tumor cell proliferation, differentiation and apoptosis in several cancers. A reverse-transcriptase subunit of telomerase (hTERT) derived peptide, GV1001 (Kael-GemVex Co. Ltd., Seoul, Korea) is a 16mer amino acid peptide, which was selected based on computer algorithms that predicted strong HLA class II binding properties encoded by multiple alleles from the HLA-DR, -DP, and ?DQ loci, thereby eliciting the T helper cell response in up to 80% of vaccinated patients and multiple nested HLA class I binding motifs. Subject to peptide processing by endogenous APCs, vaccination with GV1001 may thus recruit both CD4+ T cells and CD8+ cytotoxic T cells. Although GV1001 has been developed as a vaccine against various cancers, we have shown that GV1001 interacts with HSPs and lowers the level of intracellular and surface HSPs from various cancer cells. In hypoxic conditions, GV1001 treatment of cancer cells resulted in decreases of HSP90, HSP70, and HIF-1Ξ±. Subsequently, proliferation of cancer cells and synthesis of VEGF were significantly reduced by treatment with GV1001 in hypoxic conditions. In an experiment with a nude mouse xenograft model, GV1001 exerted a similar tumor suppressive effect, further confirming its anti-tumor efficacy. Higher apoptotic cell death, reduced proliferation of cells, and fewer blood vessels were observed in GV1001-treated tumors compared to the control. In addition, a significant decrease in Tie2+ CD11b+ monocytes, which were recruited by VEGF from tumor cells and have a critical role in angiogenesis, was observed in the GV1001-treated tumors. Collectively, the results suggest that GV1001 possesses potential therapeutic efficacy in addition to its ability to induce anti-cancer immune responses by suppressing both HSP70 and HSP90.Abstract Contents List of Figures Introduction Purpose Materials and Methods Results Discussion Conclusion References Korean AbstractDocto

    Content Analysis of Creative Problem Solving Program for Cyberbullying Prevention

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    λ³Έ μ—°κ΅¬λŠ” 창의적 λ¬Έμ œν•΄κ²°λ°©λ²•μ„ ν™œμš©ν•œ μ‚¬μ΄λ²„λΆˆλ§ 예방 ꡐ윑 ν”„λ‘œκ·Έλž¨ μ°Έμ—¬ κ²½ν—˜μ΄ μ²­μ†Œλ…„λ“€μ—μ˜ 변화에 λ―ΈμΉ˜λŠ” 영ν–₯을 ν™•μΈν•˜κ³ μž ν•˜μ˜€λ‹€. 이λ₯Ό μœ„ν•˜μ—¬ ν”„λ‘œκ·Έλž¨μ— μ°Έκ°€ν•œ μ΄ˆλ“±ν•™κ΅ 5ν•™λ…„ μ²­μ†Œλ…„ 27λͺ…μ˜ ν™œλ™μ§€μ™€ μ—°κ΅¬μžμ˜ κ΄€μ°° 자료λ₯Ό λ°”νƒ•μœΌλ‘œ λ‚΄μš©λΆ„μ„μ„ μ‹€μ‹œν•˜μ˜€λ‹€. 보닀 κ΅¬μ²΄μ μœΌλ‘œλŠ” μ°Έμ—¬ 학생 κ°„, μ°Έμ—¬ 학생-ꡐ사 κ°„μ˜ 언어와 행동 λ“±μ˜ μƒν˜Έμž‘μš©μ„ μ‚¬μ΄λ²„λΆˆλ§κ³Ό κ΄€λ ¨λœ λ‚΄μš©κ³Ό 창의적 λ¬Έμ œν•΄κ²°μ— κ΄€λ ¨λœ λ‚΄μš©μœΌλ‘œ λ‚˜λˆ„μ–΄ λΆ„μ„ν•˜μ˜€λ‹€. κ·Έ κ²°κ³Ό, μ°Έμ—¬ μ²­μ†Œλ…„μ€ 애맀λͺ¨ν˜Έν•œ μ‚¬μ΄λ²„λΆˆλ§ 문제λ₯Ό 보닀 ꡬ체적으둜 μΈμ‹ν•˜κ³  λ‹€μ–‘ν•˜κ³  적극적인 ν˜•νƒœμ˜ λ¬Έμ œν•΄κ²°λ°©μ•ˆμ„ μ œμ‹œν•  수 있게 λ˜μ—ˆλ‹€. 뿐만 μ•„λ‹ˆλΌ ν•΄κ²°λ°©μ•ˆμ„ μ‹€μ‹œν•˜λŠ” 데 μžˆμ–΄ 전체적인 상황을 κ³ λ €ν•˜μ—¬ ꡬ체적인 μ‹€μ²œ λ°©μ•ˆμ„ κ³ μ•ˆν•˜λŠ” λͺ¨μŠ΅μ„ λ³΄μ˜€λ‹€. 창의적 λ¬Έμ œν•΄κ²°μ— μžˆμ–΄μ„œλ„ ν™•μ‚°μ Β·μˆ˜λ ΄μ  μ‚¬κ³ μ˜ ν–₯상을 λ³΄μ˜€μœΌλ©°, μ•„μ΄λ””μ–΄μ˜ μ–‘μ Β·μ§ˆμ  츑면의 ν–₯상을 λ³΄μ˜€λ‹€. 이λ₯Ό ν†΅ν•΄μ„œ μ°Έμ—¬ μ²­μ†Œλ…„λ“€μ΄ 창의적 λ¬Έμ œν•΄κ²°μ„ ν™œμš©ν•˜μ—¬ μ‚¬μ΄λ²„λΆˆλ§μ— μ§€ν˜œλ‘­κ³  창의적으둜 λŒ€μ‘ν•  수 있으리라 κΈ°λŒ€λœλ‹€. μ΄λŸ¬ν•œ 연ꡬ 결과에 κΈ°μ΄ˆν•˜μ—¬ 창의적 λ¬Έμ œν•΄κ²°μ„ ν™œμš©ν•œ μ‚¬μ΄λ²„λΆˆλ§ 예방 ꡐ윑 ν”„λ‘œκ·Έλž¨ κ°œμ„ μ‚¬ν•­μ— λŒ€ν•΄ μ œμ•ˆν•˜μ˜€λ‹€.N

    Experiences During the Leave of Absence and Their Impact on Growth and Development of College Students

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    λ³Έ μ—°κ΅¬λŠ” νœ΄ν•™μ΄λΌλŠ” μƒˆλ‘œμš΄ ν™˜κ²½μ—μ„œ λŒ€ν•™μƒλ“€μ΄ κ²½ν—˜ν•œ λ‹€μ–‘ν•œ ν™œλ™μ„ μ‚΄νŽ΄λ³΄κ³ , ν•™μƒλ°œλ‹¬ κ΄€μ μ—μ„œ κ·ΈλŸ¬ν•œ κ²½ν—˜μ΄ ν•™μƒλ“€μ˜ μ„±μž₯κ³Ό λ°œλ‹¬μ— μ–΄λ– ν•œ 영ν–₯을 λ―ΈμΉ˜λŠ”μ§€λ₯Ό νƒμƒ‰ν•˜κ³ μž ν•˜μ˜€λ‹€. μ„œμšΈ μ†Œμž¬ 4λ…„μ œ AλŒ€ν•™μ— μž¬ν•™ 쀑인 νœ΄ν•™ κ²½ν—˜μ΄ μžˆλŠ” 학생 11λͺ…을 λŒ€μƒμœΌλ‘œ 면담을 μˆ˜ν–‰ν•˜μ˜€λ‹€. λ©΄λ‹΄ λ‚΄μš©μ„ λͺ¨λ‘ μ „μ‚¬ν•œ ν›„, 주제 뢄석 방법을 μ μš©ν•˜μ—¬ λΆ„μ„ν•˜μ˜€λ‹€. 연ꡬ κ²°κ³Ό, λŒ€ν•™μƒλ“€μ€ νœ΄ν•™ 쀑 지적, μ‚¬νšŒμ , 자기 성찰적 κ²½ν—˜μ„ ν•œλ‹€. ꡬ체적으둜 지적 κ²½ν—˜μ€ μžκΈ°μ£Όλ„ ν•™μŠ΅κ³Ό λͺ°μž…, ν˜„μž₯ μ²΄ν—˜κ³Ό μ§„λ‘œ μ„±μˆ™, κ°œλ³„ν™” ν•™μŠ΅ κ²½ν—˜κ³Ό 긍정적 ν•™μ—…μ •μ„œ λ“±μ΄μ—ˆλ‹€. 지적 κ²½ν—˜μ€ ν•™μƒλ“€μ˜ μ§„λ‘œ κ°€μΉ˜κ΄€μ„ ν™•λ¦½ν•˜κ³  μ§„λ‘œμ„±μˆ™λ„μ— 영ν–₯을 λ―ΈμΉ˜λŠ” κ²ƒμœΌλ‘œ λ‚˜νƒ€λ‚¬λ‹€. μ‚¬νšŒμ  κ²½ν—˜μ€ λ‹€μ–‘μ„± 이해와 개방적 νƒœλ„λ₯Ό κΈΈλ €λ˜ 인적 ꡐλ₯˜, 삢에 λŒ€ν•œ κ°€μΉ˜κ΄€κ³Ό μ§„λ‘œλ₯Ό λ°”κΏ”μ€€ λ¬Έν™”μ ‘λ³€ κ²½ν—˜, ν˜„μž₯ μ „λ¬Έκ°€ ꡐλ₯˜μ™€ μ§„λ‘œ 탐색, 큰 쑰직 리더 κ²½ν—˜κ³Ό 자기효λŠ₯감이닀. μ΄λŸ¬ν•œ κ²½ν—˜μ„ 톡해 학생듀은 사고λ₯Ό ν™•μž₯ν•˜κ³  타인에 λŒ€ν•œ 이해가 λ†’μ•„μ§€λŠ” λ“± κ°€μΉ˜κ΄€μ΄ μž¬μ •λ¦½ 된 것을 확인할 수 μžˆμ—ˆλ‹€. 자기 성찰적 κ²½ν—˜μ€ 무기λ ₯을 λ–¨μΉ˜κ³  도전해 λ³Έ κ²½ν—˜κ³Ό μž‘μ€ μ„±μ·¨, 도전적 ν•΄μ™Έ κ²½ν—˜κ³Ό μ„±μˆ™ν•œ μžμ•„κ°œλ…, λ‚˜λ₯Ό λ˜λŒμ•„λ³Έ μ‹œκ°„κ³Ό 내면적 μ„±μˆ™ 등이 μžˆλ‹€. 자기 성찰적 κ²½ν—˜μ€ 학생듀 μžμ‹ μ— λŒ€ν•œ μ„±μ°°κ³Ό μ΄ν•΄ν•˜λŠ” 과정을 톡해 내적 μ„±μˆ™μ„ μ΄‰μ§„ν•˜κ³  μžˆμ—ˆλ‹€. λ³Έλ‘ μ—μ„œλŠ” λ³Έ μ—°κ΅¬μ˜ κ²°κ³Όκ°€ μ£ΌλŠ” 이둠적 ν•¨μ˜μ™€ 정책적 μ‹œμ‚¬μ μ„ μ œμ‹œν•˜μ˜€λ‹€

    Latent Profiles of Internet Use and its Relationship with Cyber Delinquency among South Korean Adolescents

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    λ³Έ μ—°κ΅¬μ—μ„œλŠ” μ²­μ†Œλ…„λ“€μ˜ 인터넷 μ‚¬μš© μœ ν˜•μ„ ν™•μΈν•˜κ³  μ΄λŸ¬ν•œ μœ ν˜•μ΄ 사이버비행 κ°€ν•΄ 및 피해에 λ―ΈμΉ˜λŠ” 영ν–₯을 ν™•μΈν•˜κ³ μž ν•˜μ˜€λ‹€. 연ꡬλ₯Ό μœ„ν•˜μ—¬ International Self-Report Delinquency Study의 4차년도 자료(N=2,239)λ₯Ό ν™œμš©ν•˜μ—¬ μž μž¬ν”„λ‘œνŒŒμΌ 뢄석과 λ‘œμ§€μŠ€ν‹± νšŒκ·€λΆ„μ„μ„ μ‹€μ‹œν•˜μ˜€λ‹€. κ·Έ κ²°κ³Ό, 첫째, μ²­μ†Œλ…„λ“€μ˜ 인터넷 μ‚¬μš© λͺ©μ μ— 따라 관계λͺ©μ , 볡합λͺ©μ (μ €), 볡합λͺ©μ (κ³ ) 3개의 집단이 λΆ„λ₯˜λ˜μ—ˆλ‹€. λ‘˜μ§Έ, 잠재 집단이 사이버비행 κ°€ν•΄ 및 피해에 λ―ΈμΉ˜λŠ” 영ν–₯을 ν™•μΈν•˜κΈ° μœ„ν•˜μ—¬ λ‘œμ§€μŠ€ν‹± νšŒκ·€λΆ„μ„μ„ μ‹€μ‹œν•œ κ²°κ³Ό, 사이버 μ„±λΉ„ν–‰ ν”Όν•΄ 및 κ°€ν•΄λŠ” 볡합λͺ©μ (μ €) 집단과 관계λͺ©μ  집단보닀 볡합λͺ©μ (κ³ ) 집단에 μ†ν• μˆ˜λ‘ 많이 κ²½ν—˜ν•˜λŠ” κ²ƒμœΌλ‘œ λ‚˜νƒ€λ‚¬λ‹€. λ°˜λ©΄μ— 사이버 μΌλ°˜λΉ„ν–‰ ν”Όν•΄ 및 가해에 μžˆμ–΄μ„œλŠ” 볡합λͺ©μ (μ €) 집단과 관계λͺ©μ  μ§‘λ‹¨λ§Œ 차이λ₯Ό λ³΄μ˜€μœΌλ©° 관계λͺ©μ  집단에 μ†ν• μˆ˜λ‘ 사이버 μΌλ°˜λΉ„ν–‰ κ°€ν•΄ 및 ν”Όν•΄λ₯Ό 더 κ²½ν—˜ν•˜λŠ” κ²ƒμœΌλ‘œ λ‚˜νƒ€λ‚¬λ‹€. λ³Έ 연ꡬ κ²°κ³Όλ₯Ό ν†΅ν•˜μ—¬ μ²­μ†Œλ…„μ˜ λ‹€μ–‘ν•œ 인터넷 μ‚¬μš©μ— λŒ€ν•˜μ—¬ μ΄ν•΄ν•˜κ³  λΉ„ν–‰ μœ ν˜•λ³„ 맞좀 κ°œμž…μ΄ ν•„μš”ν•˜λ‹€λŠ” λ…Όμ˜λ₯Ό λ„μΆœν•˜μ˜€λ‹€.N
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