9 research outputs found
비스포스포네이트 관련 악골괴사(BRONJ)의 병기 2기에서의 외과적, 보존적 치료에 대한 비교 연구
Purpose: This study evaluated the prognosis of conservative and surgical treatment according to the staging of bi-sphosphonate-related osteonecrosis of jaw (BRONJ) by American Association of Oral and Maxillofacial Surgeons and American Society for Bone and Mineral Research.
Methods: We evaluated 53 patients of BRONJ who visited Department of Dentistry, Ajou University School of Medicine from May 2007 to February 2013. Twenty eight patients in stage 2, were divided into surgical and conservative groups with cessation of bisphosphonate therapy. Fifteen patients belonged to the conservative treatment group, in which mouth rinsing and antibiotics medication were done. Thirteen patients were treated with debridement or sequestrectomy, in the surgical treatment group. Each study list was analyzed by SPSS ver. 14.0 (SPSS Inc., USA) software and the favorable rate was verified by the Fisher exact test. P-values less than 0.05% were deemed significant.
Results: Clinical outcome was evaluated on the basis of both clinical and radiographic findings. Of all the 28 patients of stage 2, 15 patients underwent conservative treatment and 13 patients received surgical treatment. In the surgical group, 9 of 13 (69.2%) showed good prognosis, 4 of 13 (30.7%) showed recurrence. In the conservative group, 13 of 15 (86.6%) showed no change duting the follow-up period. Two of 15 patients even showed a bad prognosis, such as pain and pus discharge, which are criteria for stage 3. P-value was 0.067 (>0.05).
Conclusion: The results of the present study suggests that surgical intervention is good choice against the conservative treatment, after proper drug holidays period, while further investigation is needed for a definite solution to BRONJ
The Impact of Head Elevation on Preventing Emergence Cough during Endotracheal Extubation in Male Patients
DoctorⅠ. Introduction 1
Ⅱ. Material and Method 3
A. Ethics Statement 3
B. Patient Allocation 3
C. Anesthesia 3
D. Definition and Measurements 4
E. Statistical Analysis 5
Ⅲ. Results 6
A. Cough Profiles 6
B. Emergence and Recovery Profiles 6
C. Hemodynamics 6
IV. Discussion 7
Ⅴ. Conclusions 11
Ⅵ. List of Figures 12
A. Patient enrollment 12
B. The heart rate and mean arterial pressure during perioperative period 13
Ⅶ. List of Tables 14
A. Characteristics and intraoperative data of male patients 14
B. Incidence and severity of cough 15
C. Anesthetic emergence and recovery outcomes 16
Ⅷ. References 1
