中医定向透药疗法治疗腰椎间盘突出症85例

目的探究中医定向透药法对腰椎间盘突出症(LDH)的康复疗效。方法将我院167例LDH患者随机分为试验组85例和对照组82例,对照组予以常规保守治疗,试验组在常规保守治疗基础上给予中医定向透药疗法。疗程14 d,治疗后比较2组疼痛程度(VAS评分)、腰椎屈曲度值、日常生活活动能力(Barthel指数)的变化情况。结果试验组有效率为92.9%,显著优于对照组的82.9%(P<0.05);治疗后试验组VAS评分为(3.2±1.1)分,腰椎屈曲度值为(16.4±2.6),Barthel指数为(74.7±14.8),与治疗前比较有明显改善(P<0.05),且明显优于对照组(P<0.05)。结论中医定向透药疗法治疗LDH具有良好疗效,有助于缓解患者疼痛,改善腰椎功能,可在LDH康复治疗中推广应用

细菌铁蛋白氧化还原特性及电极活性的研究

棕色固氮菌细菌铁蛋白能直接快速地从金属铂电极上得到电子或提供电子给铂电极。经－６００ｍＶ（相对于ＮＨＥ）还原电位处理后，还原态细菌铁蛋白在可见光谱区中（３８０－５８０ｎｍ）所呈现的整体吸收光谱强度明显高于氧化态细菌铁蛋白的吸收光谱强度。经氯化钴处理后的细菌铁蛋白表现出较弱的电极活性及释放铁的速率明显下降。此外，细菌铁蛋白在体外模拟棕色固氮菌整体细胞内的微量氧环境体系中仍有氢还原现象，因而推测细菌铁蛋白在该菌体内也能进行吸氢反应。细菌铁蛋白是一种类似有吸氢氢酶功能的蛋白

Addition of alkynes and osmium carbynes towards functionalized dπ-pπ conjugated systems

碳-碳三键和碳-金属三键是两类高度不饱和的化学键。该工作发现了这两类三键之间的全新反应模式。利用该反应能把金属和有机π共轭体系有效结合，得到一类金属d轨道参与π共轭的全新大π共轭体系。化学化工学院夏海平教授课题组碳龙化学研究取得新进展，利用金属卡拜与炔烃的新反应，成功地合成了一类金属d轨道参与π共轭的全新共轭体系并在有机太阳能电池领域得到应用。该工作是在夏海平教授和南方科技大学何凤副教授共同指导下完成的。化学化工学院2016级iChEM博士生陈仕焰和南科大博士生刘龙珠为论文的共同第一作者。该工作充分体现了多学科协同创新研究优势：相关化合物合成、表征由陈仕焰、高翔、彭丽霞、张颖等完成；光电测试由刘龙珠完成；理论计算由陈仕焰、华煜晖完成。化学化工学院杨柳林副教授、谭元植教授等对研究工作给予了大力支持。【Abstract】The metal-carbon triple bonds and carbon-carbon triple bonds are both highly unsaturated bonds. As a result, their reactions tend to afford cycloaddition intermediates or products. Herein, we report a reaction of M≡C and C≡C bonds that affords acyclic addition products. These newly discovered reactions are highly efficient, regio- and stereospecific, with good functional group tolerance, and are robust under air at room temperature. The isotope labeling NMR experiments and theoretical calculations reveal the reaction mechanism. Employing these reactions, functionalized dπ-pπ conjugated systems can be easily constructed and modified. The resulting dπ-pπ conjugated systems were found to be good electron transport layer materials in organic solar cells, with power conversion efficiency up to 16.28% based on the PM6: Y6 non-fullerene system. This work provides a facile, efficient methodology for the preparation of dπ-pπ conjugated systems for use in functional materials.This research was supported by the National Natural Science Foundation of China (Nos. U1705254, 21931002, and 21975115), Guangdong Provincial Key Laboratory of Catalysis (No. 2020B121201002), Shenzhen Nobel Prize Scientists Laboratory Project (no.C17783101), and the National Key R&D Program of China (2017YFA0204902). We thank the SUSTech Core Research Facilities for the Holiba-UVISEL measurements. 研究工作得到了国家自然科学基金(U1705254、21931002、21975115)，广东省催化化学重点实验室(No. 2020B121201002)，国家重点研发计划(2017YFA0204902)，及深圳诺贝尔奖科学家实验室(C17783101)等项目资助

Optical receiver based on BCD process for plastic optical fiber

研究了光电探测器(Pd)的结构、性能以及后续放大电路,实现了塑料光纤通信的高速单片集成光接收芯片。首先,根据工艺流程和参数,采用器件模拟软件对Pd结构进行了建模,并对其光谱响应度和结电容进行了理论推导及仿真。基于CAdEnCE/SPECTrE软件和仿真得到的Pd参数对由跨阻放大器、限幅放大器和输出缓冲电路组成的后续放大电路进行了协同设计。采用0.5μM bCd(bIPOlAr,CMOS And dMOS)工艺对单个Pd以及Pd和后续放大电路单片集成电路进行了流片、封装和测试。结果表明:Pd的光谱响应曲线的峰值波长和仿真结果较一致,约为700nM,Pd结构更适合短波长探测;Pd的结电容随着反向电压的增大而减小,结电容越大,光接收芯片的带宽越小;对于650nM的入射光,在小于10-9的误码率条件下,光接收机的灵敏度为-14dbM;最后得到了150Mb/S速率的清晰眼图。实验结果显示,设计的高速单片集成光接收机可以应用于百兆速率光纤入户通信系统。The structure and characteristics of a photodetector(PD)and its post amplifiers were investigated,and a high-speed monolithic optical receiver for Plastic Optical Fiber(Pof)communication was implemented.Firstly,a model of PD structure was established and simulated in a software simulating device based on the process flows and parameters.The spectral responsibility and ajunction capacitor were also derived in theory and simulation.Then,the post amplifiers consist of a trans-impedance,a limiting amplifier and an out buffer were simulated in Cadence/spectre by using the PD parameters.Finally,by using the 0.5μm(Bipolar,CMOS and DMOS)BCD process,the single PD and the monolithic integrated circuit of PD and post amplifiers were taped out,packaged and tested.The tested results indicate that the peak of optical spectral responsible curve agrees with that of the simulated curve,and the wavelength is about 700nm.The junction capacitance of PD decreaseswith increasing of the bias voltage and the bigger the junction capacitance,the smaller the bandwidth of optical receiver.For a 650nm input light,the sensitivity of the optical receiver is-14dBm under the bit-error-rate of 10-9.Moreover,a clear eye-diagram with the speed of 150Mb/s is achieved.The designed optical receiver can be applied to 100Mb/s optical fiber communication systems.国家自然科学基金资助项目(No.61205060); 福建省自然科学基金资助项目(No.2011J01361); 福建省科技计划重点项目(No.2013H0047

Adsorptive removal of phosphate from water using Fe-Mn binary oxide coated sea sand

利用铁锰复合氧化物包覆海砂制备了一种用于污水除磷的新型颗粒状吸附剂,并对其表面特性与磷吸附行为进行了研究.扫描电镜(SEM)分析结果表明,包覆后海砂颗粒表面凹凸不平且多孔,BET比表面积由0.06增至2.52 m~2·g~(-1).磷吸附实验结果表明,包覆后海砂对磷的吸附能力显著提高,最大吸附容量为1.01~ 1.23 mg·g~(-1),优于多数文献报道的负载改性砂颗粒吸附剂;吸附动力学更符合准二级动力学方程,推测磷在包覆海砂表面发生了化学吸附;溶液pH对磷吸附有一定影响,离子强度则影响不大;共存阴离子对磷吸附影响的大小顺序为SiO_3~(2-) > CO_3~(2-) > F~- > SO_4~(2-) >Cl~-

Different Structure Integrated Photodetectors Applied in Pof Receivers

基于0.5μM标准bIPlOr、互补金属氧化物半导体和双扩散金属氧化物工艺设计了两种不同结构不同尺寸的光电探测器,包括传统的P+/n-EPI/bn+结构光电探测器和多叉指P+/n-EPI/bn+结构的光电探测器.通过仿真优化设计了光电探测器的结构参量和性能,测试结果表明:多叉指状P+/nEPI/bn+光电探测器能够改善650nM的响应度以及降低结电容.选择该结构大面积P+/n-EPI/bn+光电探测器用于和跨阻放大器以及后端放大器的单片集成,采用0.5μM标准bIPlOr、互补金属氧化物半导体和双扩散金属氧化物工艺实现了一个用于650nM塑料光纤通信的单片集成光接收芯片.该光接收芯片的测试结果表明:对650nM的入射光,在160 Mb/S速率的伪随机二进制序列以及小于10-9的误码率条件下,光接收芯片的灵敏度为-15dbM,并能得到清晰的眼图.因此,本文设计的光电探测器可以很好地应用于宽带接入网中的高速塑料光纤通信系统的光接收芯片中.Two types of photodetectors including conventional P+/N-EPI/BN+photodetector and multifinger P+/N-EPI/BN+photodetector were implemented in a standard 0.5μm Biplor,CMOS and DMOS process with different sizes.The performance and parameter of photodetectors were simulated and optimized.Results of the characteristics of photodetectors simulations and tests were presented,which showed that the multi-finger structure P+/N-EPI/BN+photodetector can improve the responsibility at 650nm and decrease the junction capacitance.The large-area multi-finger structure P+/N-EPI/BN+ photodetector was chosen for the monolithic integration with a trans-impedance amplifier and a preamplifier.A proposed monolithic optoelectronic integrated receiver was fabricated in 0.5μm Biplor, CMOS and DMOS technology for 650nm plastic optical fiber communication.The measurements of the proposed receiver were done.The receiver achieved a sensitivity of-15dBm with the bit-error-rate of 10-9 at 160Mb/s pseudo random binary sequence signal for 650nm input light.A clear eye diagram was demonstrated for 160 Mb/s pseudo random binary sequence signal.These indicate that the proposed photodetector can be employed in the receiver chip of high-speed plastic-optical-fiber-based fast ethernet system for broadband access network application.TheNationalNaturalScienceFoundationofChina(No.61205060); theNaturalScienceFoundationofFujianProvinceofChina(No.2011J01361); theKeyProjectofScienceandTechnologyofFujianProvinceofChina(No.2013H0047

Realization of a High Sensitivity Fully-integrated Receiver with Optimized Large-area Photodetector

通过仿真优化探测器的结构参数和性能,设计了基于0.25μM标准bCd(bIPlOr,CMOS And dMOS)工艺的大面积多叉指状PIn光电探测器.选择已优化的大面积光电探测器用于和跨阻放大器以及后端放大器单片集成,采用0.25μM bCd工艺实现了一个用于650nM塑料光纤通信的单片集成光接收芯片.结果表明:多叉指状PIn光电探测器对650nM入射光的响应度提高至0.260A/W,其结电容降低至4.39Pf.对于650nM的入射光,在速率250 Mb/S、误码率小于10-9的条件下,光接收芯片的灵敏度为-23.3dbM,并得到清晰的眼图.该光电探测器可用于宽带接入网中的高速塑料光纤通信系统的光接收芯片中.Multi-finger PIN photodetector was designed and optimized in a standard 0.25μm BCD(Bipolar,CMOS and DMOS)process.The optimized large-area multi-finger structure PIN photodetector was applied in the monolithic optoelectronic receiver with a trans-impedance amplifier and a pre-amplifier.Based on simulation and test results,it is shown that 650 nm responsibility of PIN photodetector is improved up to 0.260A/W and the junction capacitance is decreased down to 4.39 pF for the multi-finger structure.The receiver achieves a sensitivity of-23.3dBm with the bit-error-rate of 10-9 at 250Mb/s at650 nm.A clear eye diagram of the proposed receiver is demonstrated for 250Mb/s.Results indicate that the monolithic optical receiver can be applied to 250 Mb/s plastic optical fiber communication.TheNationalNaturalScienceFoundationofChina(No:61205060); KeyProjectofScienceandTechnologyofFujianProvince;China(No.2013H0047

Research of silicon-based monolithic integrated optical receiver for Pof communication

设计并用低成本的0.5μM bCd(bIPlOr,CMOS And dMOS)工艺实现了用于650nM塑料光纤(POf)通信的SI基单片集成光接收芯片,其中包含了与标准工艺兼容的大面积的叉指状的PIn结构的光电探测器(Pd)、跨阻放大器(TIA)以及后端放大器(PA)。采用nI公司的图形化编程软件lAbVIEW和硬件PXI并结合光学调整平台的测试方案对流片后的光接收芯片进行测试,结果表明,Pd的暗电流为PA量级,响应度为0.25A/W,电容为4.4Pf;对650nM的入射光,在180MbIT/S速率的伪随机二进制序列(PrbS)以及小于10-9的误码率(bEr)条件下,测得光接收芯片的灵敏度为-14.6dbM,并能得到清晰的眼图,包括200μMx200μM的Pd在内总的芯片面积0.9MM2,5V的电源下功耗为60MW。This paper describes a silicon-based monolithic integrated optical receiver for 650nm plastic optical fiber(Pof)communication realized in 0.5μm biplor,CMOS and DMOS(BCD)process.It consists of large area cross finger-type PIN photodetector(PD)that is compatible with standard process,transimpedance amplifier and post amplifiers.Testing scheme with the graphical programming software LabVIEW,hardware PXI and optical adjustment platform is proposed to test the optical receiver chip after tap-out.Measurement results show that the dark current of PD is at pA magnitude,the responsivity is 0.25A/W and the capacitance is 4.4pF.The sensitivity of receiver is-14.6dBm at 180Mbit/s pseudo random binary sequence(PRBS)and BERis less than 10-9 for 650nm input light.A clear eye diagram is demonstrated.The area of optical receiver is 0.9mm2 including the PD area of 200μm×200μm,and the power dissipation is 60mW with power supply of 5V.国家自然科学基金(61205060); 福建省自然科学基金(2011J01361); 中国福建省科技计划重点项目(2013H0047)资助项

基于共伴生原生混合稀土金属的永磁材料及其制备方法和应用

本发明提供一种基于共伴生原生混合稀土金属的双主相永磁材料及其制备方法和应用，其组成为：(RMaFe100-a-b-cMbBc)1-x{[(Pr1-yNdy)1-zRz]dFe100-d-e-fMeBf}x，所述永磁材料包括RMaFe100-a-b-cMbBc和[(Pr1-yNdy)1-zRz]dFe100-d-e-fMeBf两种主相，其中，RM为共伴生原生混合稀土金属，其质量组成包括：20％～32％La、48％～58％Ce、4％～6％Pr和15％～17％Nd；M为Mn、Co、Ni、Zr、Ti、Cu、Zn、Al、Ga、In、Sn、Ge和Si中的一种或多种；R为Y、La、Ce、Eu、Gd、Tb、Dy、Ho、Er、Tm、Yb和Lu中的一种或多种。由于本发明的永磁体价格低廉，而且综合永磁性能优异，因此具有非常广泛的应用价值

一种双主相烧结永磁材料及制备方法和应用

本发明提供一种双主相烧结永磁材料，其元素成分按质量比为(RcaFe100-a-b-c-dMbZrcBd)x[(Pr1-zNdz)eFe100-e-f-gMfBg]y(R1-hTh)1-x-y，所述永磁材料包括RcaFe100-a-b-c-dMbZrcBd和(Pr1-zNdz)eFe100-e-f-gMfBg两种主相，其中Rc为Ce、LaCe合金和RM中的一种或多种，其中RM为共伴生原生混合稀土金属，其质量组成包括：20～32％La、48～58％Ce、4～6％Pr和15～17％Nd。LaCe合金质量组成为：34～36％La、63～65％Ce，由于本发明的永磁体价格低廉，而且综合永磁性能优异，因此具有非常广泛的应用价值