50味中药及其复方与抗生素对河流弧菌的体外抑菌作用

用牛津杯法选择大黄、黄柏、黄连等50种单味中药进行河流弧菌、金黄色葡萄球菌体外抑菌试验,并以抗菌活性较好的药物组成二联、三联复方,药物质量浓度分别为60和240 mg·mL-1,进行中药复方抗菌活性研究,同时用抗生素进行河流弧菌药敏试验。目的是筛选出对河流弧菌敏感的中草药、抗生素及其复方。结果表明,黄连、诃子等单方对河流弧菌抑菌作用明显,为极敏感;在60 mg·mL-1低药物浓度时,黄柏、黄连组成的复方对河流弧菌抑菌作用为极敏感;在240 mg·mL-1药物浓度时,黄柏、黄连等组成的9个复方中药对河流弧菌抑菌作用属极敏感,黄连、板蓝根、黄柏等4个复方中药对河流弧菌的抑菌作用明显,为极敏感。河流弧菌对恩诺沙星、盐酸多西环素、氟苯尼考、土霉素及甲氧苄啶/磺胺甲噁唑5种药物高度敏感。部分中药对河流弧菌抑制作用不明显,黄连、板蓝根、黄柏等4个三联复方中药药效最强。可组成多种三联复方中药或中西药联用复方,均有良好的抑制作用。2018年开放课题基金项目(LYC2018RS04,闽海鸥[2018]31号)福建省自然基金项目(2016J01167,2018J01455)国家自然科学基金(31702384,31502194)福建省科技重大专项(2016NZ0001-3)2017年集美大学研究生教育教学改革研究项目(集大研No.[2017]18号)教育部鳗鱼工程研究中心开放基金项目(RE201704

Chitosan/Nonahydrate Gel Derived Fe-N-Doped Porous Carbon Sheet as High-Efficient ORR Electrocatalyst

以壳聚糖/硝酸铁凝胶为前躯体，实现了含氮高分子与金属盐的均匀混合，将凝胶冷冻干燥处理后，经过热处理和酸刻蚀得到了成分及微结构更加均匀的铁氮掺杂多孔碳片. 铁氮掺杂多孔碳片与商业铂碳相比，具有更高的起始电位，半波电位和优秀的循环性能，在碱性燃料电池的测试中实现了更高的功率密度. 铁氮掺杂多孔碳片出色的氧还原电催化性能归因于铁在壳聚糖中的原子级分散所导致的均匀分布的铁氮碳催化活性位，大的比表面积和均匀的孔道分布.The chitosan/nonahydrate gel was used as a precursor to realize the uniform mixture of N-polymer and metal salt. After lyophilization treatment, the gel went through heat treatment and acid etch. Accordingly, the Fe-N-doped porous carbon sheet with homogenous composition and microstructure was prepared. Compared with the commercial Pt/C catalyst, the Fe-N-doped porous carbon sheet exhibited more positive onset potential and half-wave potential, higher current density, and especially, excellent durability. The power density of 318 mW·cm-2 was obtained in alkaline fuel cell with the Fe-N-doped porous carbon sheet as a cathode catalyst, which is higher than 267 mW·cm-2 with the Pt/C as a cathode catalyst. The improved cell perforence with the Fe-N-doped porous carbon sheet might be contributed to the atomicaly dispersed iron in chitosan, which results in the homogenous dispersion of Fe-N-C active site, high specific surface area and pore size distribution.中科院“百人计划”和基金委 优青 (21422108)资助作者联系地址：1. 吉林大学材料科学与工程学院，汽车材料教育部重点实验室，吉林 长春 130022；2. 中国科学院长春应用化学研究所，稀土资源利用国家重点实验室，吉林 长春 130022Author's Address: 1. Key Laboratory of Automobile Materials, Ministry of Education and College of Materials Science and Engineering, Jilin University, Changchun 130012, China; 2. State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130012, China通讯作者E-mail：[email protected]

Determination of the number of ψ(3686) events taken at BESIII

The number of ψ(3686) events collected by the BESIII detector during the 2021 run period is determined to be (2259.3±11.1)×106 by counting inclusive ψ(3686) hadronic events. The uncertainty is systematic and the statistical uncertainty is negligible. Meanwhile, the numbers of ψ(3686) events collected during the 2009 and 2012 run periods are updated to be (107.7±0.6)×106 and (345.4±2.6)×106, respectively. Both numbers are consistent with the previous measurements within one standard deviation. The total number of ψ(3686) events in the three data samples is (2712.4±14.3)×10^