Design and Implementation of the Scientific Research Management System for Hospital

信息化，即国民经济和社会服务信息化，就是利用现代信息技术，在各个领域、各个层次促进社会生产力发展。在医学领域，我国的医院信息化经过近30多年的发展，医院信息管理发展已较为成熟，医学影像存储传输系统、医学检索系统、临床信息系统也有较普遍的应用。信息化已经渗透到医院管理、医疗活动的方方面面。但是医院的科研管理方面却问题重重，由于科研管理人员质量参差不齐，管理观念陈旧，管理方法单一，而且科研项目的申报手续繁多，过程复杂，人工操作容易出错等缺点，为了解决上述问题某医院的科研管理者应该采取行动建立科学的科研管理系统。 基于上述背景分析，论文结合医院科研管理工作的实际需要,为了提高科研管理工作的办公效率...Informatization is informatization of the national economy and social services.It uses modern information technology to promote the development of social productive forces in all areas and at all levels. Our hospital informatizationhas developed 30 years, the development of hospital information management has been more mature, medical imaging storage transport systems, medical retrieval systems, c...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X201323048

Ecosystem structure and function in northern Beibu Gulf: zooplankton spatial niche and its differentiation

根据2006—2007年北部湾北部海域4个航次调查资料,采用k-优势度曲线法对浮游动物种(类)群进行排序分析,运用lEVInS公式和PIAnkA指数分析了主要优势种(类)群的生态位宽度值和生态位重叠程度,并通过除趋势典范对应分析(dCCA)研究生态位分化状况。结果表明,该海区浮游动物优势种(类)群按生态位宽度值可划分为广生态位、中生态位和窄生态位三大类型。其中,广生态位的种(类)群如肥胖软箭虫、亚强次真哲水蚤、长尾类幼体等具有较强的生态适应性,生活范围较广;窄生态位的种(类)群,对环境的适应性较差,对海流和水团等环境因素的变化具有指示意义。生态位宽度能够反映种(类)群丰度季节变化,但不能反映具体丰度大小。北部湾北部全年主要优势种(类)群的生态位宽度值介于0.08—0.77之间,并且各优势种(类)群的生态位宽度差异较大,种对间生态位重叠值介于0.02—0.89之间,平均生态位重叠指数为0.45,种(类)群之间利用资源环境的互补性较强,这与海域内生境多样化并且各优势种对环境适应能力的差异存在一定联系。dCCA分析表明,影响浮游动物分布的主要因子是水深、温度和盐度,其次是叶绿素A和溶解氧。The concept of ecological niche had remained as one of the core ideas in ecological research for almost a century,which was closely linked with interspecific competition,resource utilization had played an important role in the study of community composition and function,of the relationships among species,biodiversity,community succession and population evolution.Based on four seasonal investigations( Spring 2007,Summer 2006,Autumn 2007 and Winter 2006) in northern Beibu Gulf from 2006 to 2007,the niche breadth,niche overlap,spatial differentiation and environment effects on the abundance and spatial distribution of zooplankton were studied with qualitative and quantitative methods.The cumulative top 80% of zooplankton dominant populations were selected by the K-dominant curve method,then the niche breadths and their overlaps of zooplankton were measured using the formulas proposed by Levins Niche Breadth index and the Pianka Niche Overlap index,and the spatial niche differentiation was studied by using Detrended Canonical Correspondence Analysis( DCCA) method.The results showed that the zooplankton dominant species in northern Beibu Gulf were classified in to three groups,i e.,wide niche breadth groups( Bi= 0.60—0.77),middle niche breadth groups( Bi= 0.30—0.60),narrow niche breadth groups( Bi= 0.08—0.30) based on the niche breadth value.The niche breadths of zooplankton such as Sagitta enflata,Subeucalanus subcrassus and Macrura larvae were wider,which was related with their own characteristics and the capability of adapting environment,while the species whose niche breadths were narrower such as Doliolum denticulatum and Dolioletta gegenbauri will be considered as an indicative significance for ocean currents and water masses.Niche breadth could reflect the zooplankton abundance with the seasonal dynamic changes,and also could objectively reflect the species in the habitat in which the distributions of degree but it could not reflect the Accurate zooplankton abundance.The niche breadth values of dominance zooplankton species ranged between 0.08 and 0.77 in the whole year and The niche breadth difference among the dominant populations was great; The niche overlap values of dominance zooplankton species ranged between 0.02 and 0.89 in the whole year and the average niche overlap index was 0.45,there was strong complementarity in terms of the utility of resource among zooplankton populations,which had certain relationship with northern Beibu Gulf habitat diversification and the strong complementarity in terms of the utility of resource among zooplankton populations.The Detrended Canonical Correspondence Analysis result showed that depth,temperature and salinity had more important influence on the species spatial distribution than Chlorophyll a and dissolved oxygen.海湾公益项目(201005012); 我国近海海洋综合调查与评价专项(908-01-ST09

2016年夏季南海海盆水体颗粒物粒径分布特征

颗粒物粒径分布（Particle Size Distribution,PSD）代表了颗粒物浓度与颗粒物粒径之间的关系,影响着海洋生态环境和水体光学特性等。文章基于2016年夏季航次调查的生物光学剖面数据,研究了南海海盆海域PSD的分布特征。研究发现,幂律函数可以较好地拟合南海海盆区域的PSD,对数空间中的实测的PSD与模拟的PSD平均决定系数高达0.95。PSD斜率（ξ）的分布范围为[1.27,7.65],均值为3.93±0.56。南海海盆区域表层水体的ξ均值与全球大洋表层水体的ξ均值相近,但高于海湾等表层水体的ξ均值。ξ能较好地表征颗粒物平均粒径DA的大小,两者存在明显负相关关系,即ξ值越高,DA越小;反之,DA越大。通过分析T1断面的生物光学剖面数据及总体平均的PSD剖面数据,发现PSD剖面分布特征如下:1)表层水体的ξ值相对较高,且DA值相对较低,推测可能是由于微微型藻类为主导颗粒物所致;2)ξ值极小值层出现在次表层叶绿素浓度极大值层（Subsurface Chlorophyll Maximum Layer,SCML）中,并伴随DA极大值层的出现,其原因可能是SCML中的大粒径浮游植物占比显著增加;3)弱光层中的ξ值较SCML中的高,但略低于表层的ξ值,而DA则位于表层与SCML的DA之间,这可能与浮游植物及其碎屑的絮凝、分解、沉降等过程相关。PSD特征影响着海水的固有光学特性,分析发现:由于SCML中的叶绿素浓度增加,颗粒物散射系数（bp（532））和颗粒物后向散射系数(bbp（532）)也相应呈现显著增加的趋势。弱光层中的平均bp（532）与平均bbp（532）最小。ξ与颗粒物衰减光谱斜率之间呈高分散性,Boss等（2001b）的模型适合用于粗略估算区域性的ξ分布范围及均值。国家自然科学基金(41576030,41431176,4176045,4176044,41376042);;热带海洋环境国家重点实验室自主研究项目(LTOZZ1602);;广州市科技计划重点项目(201504010034,201707020023,201607020041);;广东省科技计划重点项目(2016A020222008);;中科院A类先导专项(XDA11040302)~

长江口邻近海域夏季大中型浮游动物物种多样性、年际变化及其影响因素

利用2014—2016年毎年7月在长江口邻近海域进行的大面调查所采集的浮游动物样品,对该海域夏季大中型浮游动物的种类组成及种数平面分布进行了分析,同时结合环境参数,研究了种类组成、种数平面及年际变化的影响因素.研究结果表明:长江口邻近海域3年共鉴定大中型浮游动物165种,隶属7个门的17个类群;桡足类和水螅水母类是每年夏季优势类群;调查区大中型浮游动物种类分布大致呈现近岸低、远岸高、南部高于北部的特征;大中型浮游动物种类数没有明显的年际变化,但是种类组成有明显的年际更替.Pearson相关性分析结果显示:盐度、温度和溶解氧是影响大中型浮游动物种类数平面分布的主要环境因素;复杂的水文环境及台风过境的剧烈影响可能是造成该区域大中型浮游动物种类组成年际变化的主要原因.国家自然科学基金(41676133,J1310037);;福建省自然科学基金(2016J01196);;国家海洋局近岸海域生态环境重点实验室项目;;厦门大学校长基金(20720170077);厦门大学大学生创新创业训练计划项目(201610384120,103842017046

An ecological study on zooplankton in the northern Beibu Gulf V: the effects of microzooplankton grazing on phytoplankton in summer

2011年8月份于北部湾北部海域5个观测站位获得的分层水样,分析了表层叶绿素A含量和表层微型浮游动物丰度以及类群组成;同时于现场采用稀释培养法研究了该海域浮游植物生长率(μ)和微型浮游动物的摄食率(g)。分析和测定结果表明:调查海区的微型浮游动物丰度400—1167个/l,类群组成以无壳纤毛虫为主;浮游植物的生长率为-1.50—1.13 d-1,微型浮游动物摄食率为0.33—1.08 d-1;推算微型浮游动物对浮游植物现存量以及初级生产力的摄食压力分别为28.1%—66.0%和-7.4%—438.4%。相对于中国其他海区,8月份北部湾北部海域微型浮游动物摄食速率处于中等水平。调查期间,广西沿海高生产力海区,浮游植物生长率大于微型浮游动物动物的摄食率,浮游植物生物量处于积累期;涠洲岛以南海域,浮游植物生产力较低,微型浮游动物摄食作用是控制浮游植物生长的重要因素。In August 2011,we quantified the impact of microzooplankton grazing on phytoplankton production in the surface waters of the northern Beibu Gulf,Vietnam.Shipboard dilution incubation experiments were carried out at five stations to calculate phytoplankton specific growth rates and the specific rates of grazing losses to microzooplankton.Dilution experiments using chlorophyll a( Chl a) as a tracer were used to estimate daily rates in two size fractions; image-analyzed microscopy provided quantitative estimates of microzooplankton standing stock( including ciliate and vertebrate larvae).PFW( particle-free water) was used to dilute seawater to five target dilutions of 0%,20%,40%,60%,and 80%.Microzooplankton grazing and phytoplankton growth rates were estimated by the linear regression of AGR( apparent growth rate) versus dilution factor.We estimated the grazing impact of microzooplankton on phytoplankton by calculating the percentage of phytoplankton standing stock and potential primary production ingested.Average total chlorophyll a concentration was( 0.67 ± 0.58) μg / L.Small-celled phytoplankton dominated this particular community.A notable characteristic of the phytoplankton community structure was that nano- and picoplankton made up a significant portion.Aloricate ciliates dominated the microzooplankton samples,in particular Strombidium,which accounted for 27.2% of total aloricate ciliate abundance.In addition,loricate ciliates and copepod nauplii were recorded.Microzooplankton densityvaried from 400 to 1167 ind / L.The horizontal distribution of microzooplankton was greater in nearshore than in offshore waters.Abundance did not differ significantly with chlorophyll a concentration in this study; however,there was a positive correlation between microzooplankton abundance and temperature.The phytoplankton growth rate( < 200 μm) ranged between-1.50 and 1.13 d-1,with the highest values being associated with nearshore waters.Meanwhile phytoplankton mortality due to microzooplankton grazing( 0.33—1.08 d-1) was highest at the same nearshore sites; however,growth rates were low at these sites.Consequently,microzooplankton consumed 28.1%—66.0% of chlorophyll a standing stocks and-8.1%—438.4% of the primary production per day.However,the grazing rate of microzooplankton on nanoplankton( 2— 20 μm) varied from 1.87 to 0.52 d-1,with an average of( 0.94±0.57) d-1.Given that the rates of grazing on phytoplankton of <200 μm were lower than those on nanoplankton,we conclude that microzooplankton prefer to graze on nanoplankton.There was a positive correlation between phytoplankton growth rate and grazing rate; in addition,significant differences between grazing rate and chlorophyll a were found.This suggests that microzooplankton grazing activity is the main factor regulating the community structure and restraining the growth of phytoplankton.During the investigation period, microzooplankton grazing effectively controlled the growth of phytoplankton,consuming 176.2% of primary production on average.When grazing rates are far greater than phytoplankton growth rates,energy is transferred from lower to higher trophic levels more effectively.In the surface waters of the northern Beibu Gulf,microzooplankton largely control the growth of phytoplankton by grazing offshore rather than in nearshore waters where primary production is high.The growth and grazing rates combined promote planktonic ecosystem stability in this area.These results indicate that grazing by microzooplankton is a key process controlling the growth of phytoplankton in this area.海湾公益项目(201005012

福建绞股蓝皂苷的优化提取及其抗肝癌活性

绞股蓝素有"南方人参"美誉,含有与人参皂苷相同骨架达玛烷型结构的三萜皂苷。通过不同体积分数乙醇溶液优化提取绞股蓝皂苷,测定其抗癌活性,为后续活性化合物的分离奠定基础。利用HPLC分析绞股蓝的皂苷成分并确定提取绞股蓝皂苷的乙醇体积分数,正交实验优化提取方法,进而MTT法测定提取的绞股蓝皂苷抗肝癌活性。HPLC分析确定用体积分数75%乙醇溶液提取绞股蓝总皂苷(GYP),体积分数45%乙醇提取极性绞股蓝皂苷(GYP1),体积分数90%乙醇提取弱极性绞股蓝皂苷(GYP2);正交实验结果表明在70℃水浴中以30质量的体积分数45%乙醇加热提取12 h为最佳条件提取GYP1,在60℃水浴中以30质量的体积分数90%乙醇加热提取6 h为最佳条件提取GYP2;利用MTT法测定GYP、GYP1和GYP2对肝癌细胞的抑制作用,GYP和GYP2对肝癌细胞SMCC7721具有抗癌活性,半抑制率IC50值分别为(165.83±14.12)μg/mL和(113.97±9.26)μg/mL,GYP1没有抗癌活性,表明绞股蓝抗癌药效成分主要是由弱极性绞股蓝皂苷发挥功效

The relationship between nutrients and phytoplankton community structure in northern Beibu Gulf

根据2011年4月和8月北部湾北部(北部湾20°n以北的海域)的调查数据,北部湾北部春夏两季共鉴定出浮游植物312种,隶属于4门78属,硅藻是主要优势类群。春季优势种为细弱海链藻(THAlASSIOSIrA SubTIlIS)、丹麦细柱藻(lEPTOCylIndruS dAnICuS)、奇异棍形藻(bACIllArIA PArAdOXA)和尖刺拟菱形藻(PSEudOnITzSCHIA PungEnS);夏季优势种仅为海链藻(THAlASSIOSIrA SP.)。浮游植物群落在春季可划分为2个子群落(SPr1和SPr2),在夏季可划分为3个子群落(SuM1、SuM2和SuM3)。该海域n/P比值一直处于高的水平,绝大部分的水域表现为磷限制,这可能是硅藻大量生长所造成的。春季SPr2群落优势种的柔弱角毛藻(CHAETOCErOS dEbIlIS)与除铵盐之外的营养盐具显著相关关系,奇异棍形藻与环境因子无相关关系。夏季SuM3群落优势种的奇异棍形藻与磷酸盐具显著相关关系。分析表明,琼州海峡过道水为北部湾北部输送了磷酸盐,而硅酸盐则主要由陆地径流输入。Phytoplankton community and nutrient concentration in the northern Beibu Gulf in April and August 2011 were investigated.In this research, 312 phytoplankton taxa were identified, which belonged to four phyla and 78 genera, with Bacillariophyta being the main group.The dominant species were Thalassiosira subtilis, Leptocylindrus danicus, Bacillaria paradoxa, and Pseudonitzschia pungens in spring, and Thalassiosira sp.in summer.Phytoplankton community in northern Beibu Gulf could be divided into two natural groups in spring(spr1 & spr2) and three in summer(sum1, sum2 & sum3).N/P ratio was in a relatively high level in the study area, and most of the waters were phosphorus limitated which resulted from diatom blossom.Chaetoceros debilis was the dominant species of group spr1 and had significant correlation with nutrient in spring, except for ammonium.Bacillaria paradoxa was the dominant species of group sum3 and had significant correlation with phosphate in summer, but, it was uncorrelated with any environmental factors as the dominant species of group spr2 in spring.Phosphate was transported to northern Beibu Gulf through the Qiongzhou Strait corridor water, and silicate was input by land runoff.海洋公益性行业科研专项项目(201005012

新型稠环电子受体的界面修饰对钙钛矿太阳能电池性能的影响

钙钛矿太阳能电池(perovskite solar cells, PSCs)因具有能量转换效率(power conversion efficiency, PCE)高、成本低、易于大面积制造等优点而被科学家们广泛关注.氧化物电子传输层的合理界面设计及修饰对提高器件的PCE和工作长期稳定性有着十分重要的意义.因此,本文采用一种含有烷基噻吩基侧链的稠环电子受体材料3,9-二(2-亚甲基-(3-(1,1-二氰甲烯基)-茚酮))-5,5,11,11-四(5-己基噻吩)-二噻吩并[2,3-d:2′,3′-d′]-s-引达省[1,2-b:5,6-b′]二噻吩(3,9-bis(2-methylene-(3-(1,1-dicyanomethylene)-indanone))-5,5,11,11-tetrakis(5-hexylthienyl)-dithieno[2,3-d:2′,3′-d′]-s-indaceno[1,2-b:5,6-b′]dithiophene, ITIC-Th)修饰TiO2电子传输层,制备高效稳定的平面结PSCs.研究结果显示,ITIC-Th的界面修饰改善了TiO2薄膜的形貌、接触角等性质,促进了钙钛矿晶粒的高质量生长,大幅度减少了器件表界面的电荷复合,明显提升了光生载流子的抽取率和输运效率,使经ITIC-Th界面修饰的PSC的PCE从未经界面修饰的15.43%显著提高到18.91%.与此同时,器件稳定性的研究结果显示,在室温和湿度为30%的条件下,经ITICTh界面修饰的PSC的PCE在放置约1000 h后依然保持原来的90%,明显高于未经界面修饰的PSC.研究结果对PSC光伏性能的提升具有重要的实际应用价值和学术意义.国家自然科学基金(61605164);;\n陕西省重点科技创新团队计划(2016KCT-28);;\n陕西省重点研发计划(2017ZDXM-GY-046);;\n福建省科技厅高校产学合作项目(2016H6023)资

Study on Production Planning System of AB Company

为了改变AB公司现有的不符合市场需求和竞争环境要求的生产计划系统,实现最好的客户服务、最小的库存投资和高效率的运作等3个目标,对企业的生产计划系统进行了重新设计,并综合应用平准化方法和订货点法等生产计划方法,建立了新的生产计划系统.通过对新生产计划系统研究及其模拟运行结果的分析,得出以下主要结论:(1)根据需求拉动生产,产品库存可以得到明显的降低,而且订单满足率可以得到提高;(2)生产供应可以更快速地满足市场需求;(3)各生产工序的生产可以均衡地进行;(4)新生产计划系统是一个较好的可视化管理系统.In order to improve the existing production planning system of AB Company, which is not fit to market demand and competition environment, and accomplish three purposes: the highest customers′ service level, the minimum inventory investment and the highest production efficiency, we redesign the production planning system of AB Company. We set up a new production planning system by synthetically using methods of Heijunka and reorderpoint. According to the study on the new production planning system and the analysis of the simulation results of its operation, we conclude that: (1)The adoption of the new production planning system could not only decrease the inventory of finished goods and workinprocess products but also improve the orders fulfillment level.(2)Production supply could more quickly response to marketing demand. (3)The production loading of all processes could be balanced.(4)The new production planning system is a good visual management system

Historical simulation of tropical cyclone tracks in Northwest Pacific

Northwest Pacific is the most active area for tropical cyclones(TCs).Intensified TCs usually cause natural disasters, leading to tremendous losses in life and property.Statistical analyses of the historical records of tropical cyclones are crucial to the risk assessment of TCs.However,current historical records of TCs are out of the requirement of a refined risk assessment in coastal area.In this study, the climatic properties (including annual frequency, location,path movement and intensity change,etc.) of TCs derived from the International Best-Track Archive for Climate Stewardship(IBTrACS) database have been analyzed,and a synthetic model of the TC tracks over Northwest Pacific has been developed.The model includes four parts: genesis model,movement model, lysis model and intensity model.The model is evaluated by comparing an ensemble of simulations to the historical records from the perspective of spatial track density,annual landfall rate and frequency distribution of maximum landfall wind speed.Results show that the model performs well according to a few of diagnostics,and the simulations and observations are statistically indistinguishable. Therefore, the model can be used to generate synthetic tropical cyclones for a refined risk assessment of TCs over Northwest Pacific,and can improve the reliability of cyclone risk disaster assessment