2,936 research outputs found
The Optimization and Application of Indicator System of Liquidity Risk Management in Security Company
随着证券行业创新业务快速发展,资本消耗型业务增长迅速,行业平均杠杆率快速提升,加之表外业务如担保、流动性支持承诺的履行导致证券公司流动性需求快速增加。证券公司融资主要通过向股东融资、发债、银行授信借款等渠道,稳定的、可用于解决流动性风险的融资手段有限。证券公司的风险管理水平有待提升,经营实践中短期负债匹配长期资产,资产负债结构失衡等问题时有发生。上述原因的综合作用导致证券公司流动性风险隐患增加,流动性风险逐步显现。 将流动性风险管理定位于满足监管要求已经难以适应发展的需求,证券公司必须进行主动性管理,全面优化监测、计量工具,提升流动性风险的管理水平。本文从流动性风险的概念入手,分析了证券公司...Because of fast development of innovative security business, capital consumption business experiences a rapid growth, resulting in the increase of average leverage ratio. Expansion of off-balance-sheet activities involved with note insurance facilities and bank loan commitment further accelerates the circulation demands. Currently, financing instruments employed by a security company mainly covere...学位:会计硕士院系专业:管理学院_会计硕士学号:X200615709
Characterization and function analysis of DNA replication enzymes from Hyperthermophilic archaea Palaeococcus pacificus DY20341
DNA是至今发现的绝大多数生物遗传信息的携带者。DNA复制机制保证了细胞分裂期间遗传信息的复制和传递,是维持生物遗传稳定性的前提。DNA复制过程涉及几十种蛋白和酶的参与以确保遗传信息被准确而及时的复制。 研究DNA复制对人类疾病,特别是肿瘤及传染病的机理探索有至关重要的意义。然而参与真核生物(包括人类)DNA复制的酶系非常复杂,对真核生物DNA复制机制的研究面临着诸多挑战。细菌的DNA复制系统相对简单,但其复制酶系与真核生物差别较大。古菌的复制酶系与真核生物的复制酶系相似,而且相对简单。因此古菌可以作为研究真核生物DNA复制的一个简易模型。本文参照本课题组总结的T.kodakarensis菌...DNA is the carrier of genetic information of most organisms that have been found so far. The mechanism of DNA replication ensures the duplication and transfer of genetic information during cell division, so it is the precondition of maintaining genetic stability. The process of DNA replication involves dozens of proteins. Studying the mechanism of DNA replication has vital significance for explo...学位:理学硕士院系专业:生命科学学院_微生物学学号:2162013115251
Cyclin Dependent Kinase 5 promotes invasion and metastasis of Hepatocellular Carcinoma
肝细胞癌(HepatocellularCarcinoma,HCC)在所有恶性肿瘤导致的死亡原因中占第三位,其发病率居恶性肿瘤的第六位。肝癌具有的高复发以及高转移,使肝癌愈后很差,而导致肝癌高复发和高转移的机制还不是很清楚。最近研究表明细胞周期蛋白激酶家族蛋白在上述调控过程中具有重要作用。 细胞周期素依赖蛋白激酶家族中的一个特殊蛋白:细胞周期素依赖蛋白激酶5(CyclinDependentKinase5,CDK5)引起了我们的注意,CDK5被认为主要在神经系统发挥作用。但是,最近有实验证据表明CDK5在非神经组织内同样发挥着重要的作用,尤其在一些恶性肿瘤的进展过程中(包括肿瘤细胞的增殖和转移)...Hepatocellular Carcinomais(HCC) is the third cause of cancer related death and ranks sixth in the world among all malignancies, Metastasis and recurrence are the major risk factors for poor prognosis of liver cancer.While, the mechanism underlie the high recurrence and metastasis of Hepatocellular Carcinoma is still unclear. Recent findings indicate that Cyclin Dependent Kinase(CDKs) family protei...学位:医学硕士院系专业:医学院_外科学学号:2452013115352
Design and Implementation of Police Criminal Investigation Management Information System
随着科技的进步和社会的发展,社会阶层和利益分配发展改变,对我国社会和谐带来很大冲击。各种刑事类案件频发,给传统的侦查手段和工作方式带来了很大的考验。为贯彻科技强警战略,促进刑事侦查工作更好的顺利进行,有效打击犯罪分子、维护社会安定秩序,就必须加快现代化建设步伐、加快公安刑事工作信息化,提高刑事侦查队伍的整体素质和战斗力。 警用刑事侦查管理信息系统基于B/S模式架构,选择Java语言、J2EE企业级应用、SSH框架,及Oracle数据库开发平台进行系统需求分析,依据软件工程设计思想,详细设计和实现了该系统。本警用刑事侦查管理信息系统包括现场勘查管理、案件受理管理、设备管理、公文管理、物证管理、...With the progress of science and technology and the development of the society, the social class and interest distribution development are changing which cause the great impacts to the social harmony of our country. More various criminal happening, that brings more workload and difficulties to the traditional way of investigation means and working way. To implement the strong police strategy in sc...学位:工程硕士院系专业:软件学院_工程硕士(软件工程)学号:X201323182
等离子体反应器流场、温度场和浓度场的参数研究
文献[3,4]表述了描述等离子CVD化学反应器流场的数学物理模型,并利用Patankar方法对冷热流场作了求解。本文在此基础上就影响反应器流场、温度场和浓度场的有关参数作了理论研究。所研究的问题有:冷热流场的差别,喷射环缝密度和主流旋转速度对流动的影响。所得结果清楚地表明:这些参数的选择对反应器的性能有着不同程度的影响,而有些影响则是本质的
Vibration Damping of Carbon Nanotube Assembly Materials
Vibration reduction is of great importance in various engineering
applications, and a material that exhibits good vibration damping along with
high strength and modulus has become more and more vital. Owing to the superior
mechanical property of carbon nanotube (CNT), new types of vibration damping
material can be developed. This paper presents recent advancements, including
our progresses, in the development of high-damping macroscopic CNT assembly
materials, such as forests, gels, films, and fibers. In these assemblies,
structural deformation of CNTs, zipping and unzipping at CNT connection nodes,
strengthening and welding of the nodes, and sliding between CNTs or CNT bundles
are playing important roles in determining the viscoelasticity, and elasticity
as well. Towards the damping enhancement, strategies for micro-structure and
interface design are also discussed
Wide-Range Tunable Dynamic Property of Carbon Nanotube-Based Fibers
Carbon nanotube (CNT) fiber is formed by assembling millions of individual
tubes. The assembly feature provides the fiber with rich interface structures
and thus various ways of energy dissipation, as reflected by the non-zero loss
tangent (>0.028--0.045) at low vibration frequencies. A fiber containing
entangled CNTs possesses higher loss tangents than a fiber spun from aligned
CNTs. Liquid densification and polymer infiltration, the two common ways to
increase the interfacial friction and thus the fiber's tensile strength and
modulus, are found to efficiently reduce the damping coefficient. This is
because the sliding tendency between CNT bundles can also be well suppressed by
the high packing density and the formation of covalent polymer cross-links
within the fiber. The CNT/bismaleimide composite fiber exhibited the smallest
loss tangent, nearly as the same as that of carbon fibers. At a higher level of
the assembly structure, namely a multi-ply CNT yarn, the inter-fiber friction
and sliding tendency obviously influence the yarn's damping performance, and
the loss tangent can be tuned within a wide range, as similar to carbon fibers,
nylon yarns, or cotton yarns. The wide-range tunable dynamic properties allow
new applications ranging from high quality factor materials to dissipative
systems
Investigation of the role of innate immunity in pathogenesis of autoimmunity-associated pulmonary fibrosis
目的:肺纤维化(Pulmonaryfibrosis,PF)是一种慢性、致死性、弥散性的间质性肺病。在一些自身免疫病,比如系统性硬皮病(Systemicsclerosis,SSc)和原发性干燥综合征(primarySjögren’ssyndrome,pSS)里,PF也是一种常见的并发症并且是导致病人死亡的主要因素之一。值得注意的是,虽然这些自身免疫病患者都有自身免疫反应,但只有部分病人患有PF。这一现象表明除了自身免疫外,还有一些其他因素参与了PF的发生。但目前为止,自身免疫病相关的PF的发病机制仍然不清楚,所以难以进行有效地治疗。在这项研究里,我们采用了遗传学和实验动物学的方法来研究...Objective: Pulmonary fibrosis (PF) is a chronic, lethal, diffuse interstitial lung disease. In autoimmune diseases, such as systemic sclerosis (SSc) and primary Sjögren’s syndrome (pSS), some patients also suffer from PF which is one of major causes of death in patients. Notably, although all SSc and pSS patients are characterized with autoimmunity, only some patients develop PF. This suggest...学位:理学硕士院系专业:医学院_微生物学学号:2452014115348
Bio-Inspired Aggregation Control of Carbon Nanotubes for Ultra-Strong Composites
High performance nanocomposites require well dispersion and high alignment of
the nanometer-sized components, at a high mass or volume fraction as well.
However, the road towards such composite structure is severely hindered due to
the easy aggregation of these nanometer-sized components. Here we demonstrate a
big step to approach the ideal composite structure for carbon nanotube (CNT)
where all the CNTs were highly packed, aligned, and unaggregated, with the
impregnated polymers acting as interfacial adhesions and mortars to build up
the composite structure. The strategy was based on a bio-inspired aggregation
control to limit the CNT aggregation to be sub 20--50 nm, a dimension
determined by the CNT growth. After being stretched with full structural
relaxation in a multi-step way, the CNT/polymer (bismaleimide) composite
yielded super-high tensile strengths up to 6.27--6.94 GPa, more than 100%
higher than those of carbon fiber/epoxy composites, and toughnesses up to
117--192 MPa. We anticipate that the present study can be generalized for
developing multifunctional and smart nanocomposites where all the surfaces of
nanometer-sized components can take part in shear transfer of mechanical,
thermal, and electrical signals
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