中药沐足结合护理干预治疗护理人员下肢静脉曲张的效果观察

目的探讨中药沐足结合护理干预在下肢静脉曲张护士中的应用效果。方法选取某三甲综合性医院患有下肢静脉曲张的临床护士60例为研究对象,应用随机数字表法分为两组,各30例。两组研究对象均行基础护理,对照组采用医用的循序减压弹力袜进行治疗,观察组实施中药沐足结合护理干预措施。2个月后比较两组患者疗效。结果观察组研究对象静脉曲张恢复总有效率高于对照组,观察组研究对象经过3个疗程的治疗,痊愈12例,显效l3例,有效4例;对照组分别为痊愈5例,显效8例,有效9例;观察组、对照组临床治愈率和总有效率分别为40.00%、96.67%和16.67%、73.33%。差异有统计学意义(P<0.05)。结论中药沐足结合护理干预可以改善下肢静脉曲张的临床症状。福建中医药大学2016年临床专项校管课题(XB2016085

嘌呤受体P2X_7激活谷氨酸受体NMDA引起视网膜神经节细胞凋亡

【目的】研究嘌呤受体P2X7和谷氨酸受体NMDA激活诱导大鼠视网膜神经节细胞(RGC)凋亡的相互作用机制。【方法】①对新生Long-Evan大鼠进行上丘注射荧光标记物Aminostilbamidine标记RGC,NMDA受体通道拮抗剂MK-801、APV和Memantine分别与P2X7受体激动剂BzATP共培养,检测它们对体外培养RGC存活率的影响;②未经Aminostilbamidine标记的新生大鼠RGC,以10μmol/L钙离子(Ca2+)荧光染料Fura-2标记后,利用Ca2+影像测定仪分别测定BzATP及三种NMDA拮抗剂对RGC胞内Ca2+浓度的影响。【结果】(1)三种NMDA拮抗剂均分别不同程度阻断BzATP引起的RGC凋亡。BzATP在50μmol/L浓度下,约杀死(36%±2%)的RGC,而MK-801(10μmol/L)、APV(100μmol/L)和Memantine(100μmol/L)则均可明显减轻BzATP对RGC的毒性作用,使RGC存活率分别提高至(96%±4%,P<0.001)、(80%±5%,P=0.010)和(76%±9%,P=0.144)。(2)BzATP可引起RGC胞内Ca2+持续升高,在50μmol/L浓度下可使胞内Ca2+升高至(1183±109)nmol/L。而MK-801(10μmol/L)、APV(300μmol/L)和Memantine(30μmol/L)则均可显著降低BzATP介导的Ca2+升高幅度,分别为(76%±7%,P=0.003)、(51%±17%,P=0.033)和(55%±16%,P=0.025)。【结论】NMDA受体拮抗剂可阻断嘌呤受体P2X7激活诱导的RGC凋亡。P2X7受体和NMDA受体通道激活可能共同介导着兴奋性神经毒作用且P2X7在NMDA受体的上一环节先起作用

以精簡 之篩網法評估咀嚼效率

The assessment of masticatory efficiency may be quantified by the particle size distribution of comminuted food. The aim of the present study was to simplify the sieving method and develop a simple and reiable model for future studies. Eighteen volunteers, 9 males and 9 females, with complete and natural dentition and free of temporomandibular disorders participated. The age of the volunteers ranged from 22 year-old to 26 year -old. Three partial or complete denture wearers were also examined for reference. The testfood used was a whole alomnd piece. The unilateral chewing test, performed by each subject, consisted of chewing on their right and left dentition separately for five times. At each trial, one almond piece was chewed 10 times. The comminuted food particles was expectorated and washed out in a beaker. The contents were then sieved in a stack of sieves with 2.0 mm, 1.4 mm, 1.0 mm and 0.5 mm apertures. After drying, the percentage of the food particles by weight that remained on each sieve was calculated. The expression of masticatory efficiency influenced by the parameters such as gender, apertures of the sieve and chewing side in addition to the interaction among them were observed by means of the generalized estimation equation (GEE), and the difference between subjects with natural and artificial dentition were also compared. It was found that no significant differences between gender, the four different sieves and chewing side and their interaction existed. The ability of the denture wearers to diminish an almond into particles less than 2.0 mm in diameter was about 60% that of subjects with natural dentition. Based on the results of the limited sample size, the difference in gender and chewing side can be neglected. Due to the less amount of comminuted food particles that remained on the 1.4 mm sieve, the stack of sieves with 2.0 mm, 1.0 mm and 0.5 mm apertures seemed to be sufficient for and effective experimental design for the evaluation of masticatory efficiency, and the 2.0 mm sieve possessed the strongest power of explanation for chewing efficiency among them

全球氢能产业发展战略与技术布局分析

：随着全球气候压力增大以及能源转型加速，氢能以其清洁、灵活高效和应用场景丰富的优 势受到全球瞩目。２０００年以来，日本、美国、欧洲等发达国家和地区纷纷将氢能上升到能源战略高 度，通过战略布局、项目开发以及示范应用，在氢能产业发展上取得了实质性进展。本文梳理和分 析了各主要国家氢能产业战略重点、目标和发展水平，从文献计量角度对比分析了中国与氢能先行 国家的基础研究和技术储备。研究表明，全球新一轮氢经济浪潮已经拉开序幕，各主要国家正在加 速布局氢经济；与国际氢能先行国家相比，中国氢能在顶层设计、产业技术掌控以及产业发展水平 上有一定差距。建议中国进一步加强战略引导；产学研结合提高关键材料和设备的国产化水平；发 挥资源优势，积极布局绿色氢经济；同时重视氢能下游多元化利用。</p

The occurrence of polycyclic musks in a typically wastewater treatment plant

多环麝香在日常生活中被广泛使用,在生产和使用过程中会经过污水处理系统而进入环境中.研究了日用化妆品生产工厂排放的多环麝香在污水处理系统中污水和污泥的污染特征.在大型日用化妆品生产工厂污水处理厂的污水和污泥中均检测出较高浓度的多环麝香,HHCB和AHTN是两种主要污染物.其中多环麝香在污水处理系统进水中质量浓度范围为4.7(AHMI)～550 μg·L~(-1)(HHCB),出水中质量浓度范围为:低于检测限(AHMI)～32.1μg·L~(-1)(HHCB),污泥(干物质量)中多环麝香的含量范围为1.78(AHMI)～566 mg·kg~(-1)(HHCB).污水处理系统污水中多环麝香的去除效率非常高,达到了90%以上,然而,污泥中却富集了大量的多环麝香,表明污水中的多环麝香很大一部分转移到了污泥中,从而可能成为环境中一种潜在的多环麝香污染源

具有力学性能的非晶态吸氢合金及其制备方法

本发明涉及一种具有力学性能的非晶态吸氢合金及其制备方法，其化学通式为（ZrTi）0.5（Ni0.6Cr0.1Mx）2.3~3，式中：M是Co、Cr、Mn、V、Fe、Dy、Er中的一种或两种以上，0.1≤x≤0.3。该方法采用如下步骤：配料：按照化学式（ZrTi）0.5（Ni0.6Cr0.1Mx）2.3~3中的成分的重量百分比。熔炼：采用真空电弧或真空感应熔炼在氩气保护下熔炼均匀并快速冷却制成晶态合金铸锭。甩带：将铸锭破碎成小块体，将小块体放入外径14mm，内径11mm的底部带小孔的石英管中，在真空甩带炉