A Study on the marketing strategy of China Moblie Ningde subsidiary company in rural market

中国移动宁德分公司从2005年开始，响应中国移动通信集团公司的号召，整合各方资源大力推进新农村策略的实施。新农村策略实施至今，网络覆盖率达到100％，农村渠道覆盖率51％，农村业务收入占比56.08％，整体情况良好，但宁德移动在发展农村市场的过程中也陆续暴露出一些问题，包括农村信息化产品不足、竞争对手与宁德移动差距逐渐缩小影响了客户规模的扩大和客户的稳定性、农村市场营销资源调配方面缺乏经验导致部分促销效果不够理想等。 本文应用市场营销理论，对宁德移动农村市场营销策略进行研究。研究结果认为，宁德移动应以农村信息化建设为切入点，以用户需求为导向，分阶段、分步骤，从用户需求层面、渠道与资源的拓展层...China Mobile Ningde Subsidiary Company starting from 2005, to respond to the call of China Mobile Communication Group Company,has been integrating resources from all aspects to advance vigorously the implementation of the new countryside strategy.Ever since then, the overall situation has been good ,the network coverage fraction achieving 100%, the countryside channel coverage fraction reaching 51...学位：工商管理硕士院系专业：管理学院工商管理教育中心（MBA中心）_工商管理硕士(MBA)学号：X200515511

Control method for aircraft wake vortex based on Rayleigh-Ludwig instability

在飞机飞行的过程中尾涡会伴随着升力产生,威胁后机的飞行安全.在简化机翼模型上添加扰流片,通过一个矩形翼以引入一个与主翼尾涡大小不同、方向相反的小涡,构建尾流自消散四涡系统,以期诱发尾涡的rAylEIgH-ludWIg相交不稳定性.通过改变扰流片的大小形状,调整模型的攻角和拖曳速度,采用粒子图像速度场仪测量系统定量研究在低雷诺数下单主翼尾涡发展特性以及双涡相互作用特性.研究表明:在未添加扰流片时,尾涡环量在45个翼展内相对于初始环量基本保持不变;在添加扰流片的情况下尾涡的环量衰减可以达到35%~55%,而未添加的基本翼型的尾涡的环量则几乎保持不变,这说明添加适当的扰流片能诱发尾涡的rAylEIgH-ludWIg相交不稳定性,加速尾涡的消散,当小涡和主涡的初始环量比为-0.489、初始距离比为0.5时,45个翼展范围内,尾涡环量衰减55.9%.本文系统性的实验结果可以为低尾流机翼的设计提供参考依据.The aircraft wake vortex is an inherent flow phenomenon due to the lift generation mechanism,which has a negative impact on the flight safety.By adding a set of specially designed spoiler,a rectangular wing was designed to generate a pair of weaker vortices,which had different sizes and opposite direction compared to main wing vortices,thereby constructing a self-destructive four-vortex wake system to induce Rayleigh-Ludwig instability.Under different experimental conditions,in terms of changing the size or shape of the spoiler,towing speed and angle of attack,the wake vortex development of the test model,that both with and without spoiler,as well as the circulation analysis,were acquired particle image velocimetry( PIV) measurements under the low Reynolds number.The study demonstrates that the decrease in circulation was 35% to55% in 45 wingspans when spoilers are introduced,whereas the counterpart of the baseline airfoil,without spoilers,is nearly kept steadily,which reveal the application possibility of Rayleigh-Ludwig instability in alleviating the wake vortex.As the initial circulation ratio equals to- 0.489 and the initial distance ratio is0.5,the circulation of the primary vortex reduce most significantly( 55.9%) in 45 wingspans.Results would provide a scheme in the design of airfoils with weaker vortices.国家自然科学基金(11072206

The protective effects of compound sarcopyramis nepalensis wall on acute hepatic injury in mice

目的观察复方风柜斗草对四氯化碳(CCl4)引起的小鼠急性肝损伤的保护作用。方法将小鼠随机分为空白组、模型组、复方风柜斗草低剂量组(2.2 g/kg)、中剂量组(4.4 g/kg)、高剂量组(8.8 g/kg)和联苯双酯阳性对照组(0.2g/kg)。空白组与模型组给予1%羧甲基纤维素钠(CMC-nA)水溶液,其他组给予相应的药物,1次/d,连续灌胃给药10 d后,除正常组外,腹腔注射CCl4致小鼠急性肝损伤。检测肝组织中的超氧化物歧化酶(SOd)及血清中丙氨酸氨基转移酶(AlT)、天冬氨酸氨基转移酶(AST)的活性,同时检测血清中总胆红素(T-bIl)、直接胆红素(d-bIl)及肝组织中丙二醛(MdA)的水平,并计算肝脏指数。结果预先给予复方风柜斗草能显著降低急性肝损伤小鼠体内T-bIl、d-bIl、AlT、AST和MdA的水平,并升高肝组织中SOd活力。结论复方风柜斗草对CCl4致小鼠急性肝损伤具有保护作用,其机制可能与其所具有的抗脂质过氧化和清除体内过多氧自由基的作用有关。Objective To observe the protective effects of compound sarcopyramis nepalensis wall against tetrachloride( CCl4)-induced acute hepatic injury in mice.Methods The mice were randomly divided into normal group,model group,low dose compound sarcopyramis nepalensis wall group( 2.2 g / kg),medium dose group( 4.4 g / kg),high dose group( 8.8 g / kg),and positive control( biphenyldicarboxylate) groups( 0.2 g / kg).The mice were ig pretreated with compound sarcopyramis nepalensis wall and biphenyldicarboxylate once daily for consecutive 10 d,respectively.The mice in the normal and model groups were given 0.1% CMCNa,the water-solution instead.Then,acute liver injury in mice was induced by ip injection of CCl4.The activities of serum ALT and AST,hepatic SOD,and the level of serum T-BIL and D-BIL,hepatic MDA were also determined,the hepatic indices were calculated.Results The activities of ALT and AST,the level of T-BIL,D-BIL and MDA were significantly decreased by compound sarcopyramis nepalensis wall pretreatment,while activity of SOD in hepatic tissues was markedly increased.Conclusion Compound sarcopyramis nepalensis wall has protective effects against CCl4-induced acute hepatic injury in mice,and the mechanisms might be associated with its anti-oxidative and scavenging free radical activity

养正消积胶囊辅助GP方案治疗晚期非小细胞肺癌临床研究

目的观察养正消积胶囊辅助GP方案治疗晚期非小细胞肺癌(NSCLC)的临床疗效。方法采用随机数字表法将89例晚期NSCLC患者分为对照组44例及观察组45例。2组均采用GP方案;观察组并予养正消积胶囊,每次4粒,每日3次,口服。2组均21d为1个周期,连续治疗2个周期,随访1年。观察2组治疗前后Ki67、Bax、Bcl-2蛋白表达及肿瘤标志物[血管内皮生长因子(VEGF)、骨桥蛋白(OPN)、癌胚抗原(CEA)、糖类抗原199(CA199)]、中医症状评分、生活质量评分,比较2组客观缓解率(ORR)、疾病控制率(DCR)、无进展生存时间(PFS),监测不良反应。结果观察组ORR、DCR明显优于对照组(P<0.05)。与本组治疗前比较,观察组治疗后、随访1年VEGF、OPN、CEA、CA199水平明显降低(P<0.05);对照组治疗后上述指标明显降低(P<0.05),随访1年CEA水平明显降低(P<0.05)。与本组治疗前比较,2组治疗后Ki67、Bcl-2蛋白表达明显降低,Bax蛋白表达明显升高(P<0.05);2组治疗后比较,观察组Ki67、Bcl-2蛋白表达低于对照组(P<0.05),Bax蛋白表达高于对照组(P<0.05)。与本组治疗前比较,2组治疗后中医症状评分(神疲乏力、胃纳少馨、腰膝无力、夜尿频多、头晕目眩)、生活质量评分(躯体功能、认知功能、社会功能、情绪功能)明显改善(P<0.05);2组治疗后比较,观察组上述评分改善明显优于对照组(P<0.05)。观察组PFS明显长于对照组(P<0.05),不良反应明显低于对照组(P<0.05)。结论养正消积胶囊辅助GP方案治疗晚期NSCLC可有效降低患者肿瘤标志物水平,改善生存质量,减少吉西他滨和顺铂的不良反应,提高疗效。福建省卫生厅中医药科研专项课题(wst201210

改良分子信标-双重实时荧光PCR快速检测SARS病毒

目的建立改良分子信标-双重实时荧光PCR检测SARS病毒的方法,用于SARS的早期诊断和动物溯源。方法利用改良分子信标技术、装甲RNA和双片段双色荧光技术,根据GenBank公布的SARS病毒聚合酶基因1b的阅读开放框架结构的保守序列,自行设计一对引物和探针,以部分临床标本的酶联吸附实验结果和传统细胞培养方法作为对照,建立分子信标检测SARS病毒的方法。对368份临床标本(咽漱液、血液、粪便、尿液)、52份细胞培养液和50份动物标本进行荧光PCR扩增。结果分子信标检测SARS病毒的方法灵敏度为10～100个拷贝ml,与流感病毒等呼吸道病毒无交叉反应。分子信标检测368份临床标本,20份阳性。其中确诊病例阳性率为21.27%(1047),确诊病例的咽漱液阳性率为43.48%,还分别从粪便和血清中检测到SARS病毒。52份细胞培养液,29份阳性,阳性率为55.77%。50份动物标本,23份阳性,阳性率为46%。结论改良分子信标-双重实时荧光PCR检测SARS病毒方法灵敏度高、特异性强,可用于SARS的临床早期诊断和动物溯源

Usability assessment framework for buildings : a case study of school buildings in Hong Kong

Building performance assessment must address questions of "who", "what" and "how" to assess, it can be summarized in a formula: Context + Mechanism = Outcome, the context includes two parts, type of building and performance subject. A typical research work will choose one type of building and one subject, and develop a tool for it and do some analysis on the outcome. The research works of this kind are abundant. But in terms of mechanism, they are actually much alike, of which the two most typical ones are Professional-only model and POE process. The absence of practice to enhance the users’ capacity to conduct building performance assessment triggers the author to introduce the concept of usability, with spirit of “getting closer to users”, and to propose a usability assessment framework to fill up this gap in research field. The exploration of usability assessment is divided into two parts: theoretical construction and practical implementation. In the first part, author will review relevant theories at roots (including at least community psychology, evaluation capacity building (ECB), process in use and equal opportunity theory) and general empowerment evaluation, to come up with a tentative usability assessment framework, of which the empowerment evaluation is the key element, which is initially defined by Fetterman (1994) as “the use of evaluation concepts and techniques to foster self-determination", it takes the “give someone a fish and you feed her for one day; teach her to fish, and she will feed herself for the rest of her life” concept. The second part of practical implementation is dealing with some aspects identified in the first part. Indoor Environmental Quality (IEQ) is chosen as the subject and School type buildings are selected, together they form the case study for new practice’s demonstration and development. In each case, participant observation will be employed for addressing issues of “giving empowerment evaluation” and “effective empowerment settings”. Survey will be used for addressing the aspect of “user interpretation of performance assessment”. It must be emphasized that theoretical construction is the crux of the study, the second implementation part will serve to address certain aspects identified in part one and help to refine the framework in addition to demonstrate it in reality. The results are analyzed and the lessons learned are discussed in chapter 6 and the tentative framework was refined correspondingly. This study breaks the routine of current typical researches only focus on results and pays attention to evaluation process as well. It tempers the ethos of the generalization from building performance assessment results by professionals with a fresh emphasis on specificity of each particular building through a generalizable mechanism by users so that the usability could be enhanced. The new roles for building professionals and users were created. This study constructs the theoretical foundation for further development, which would enrich or complement current practices in many aspects.published_or_final_versionReal Estate and ConstructionDoctoralDoctor of Philosoph

Construction and application of digital seismic network in Wenchuan earthquake fault

为了提高对"5.12"大地震灾害监视和预警的能力,了解地震孕育、发生及发展,研究汶川地震发震机理、地震复发周期和余震的迁移规律,"龙门山断裂带地震台网"建设,在震后迅速展开。该台网于2008-06-02开始正式传输地震数据,为灾后重建选址、地震科学钻探选址提供了可靠数据,同时也为研究龙门山断裂带余震分布情况、余震的迁移方向以及判断断层活动状况提供了科学依据。本文从台网选址、台网设计与建设、台网运行与管理、监测效能等方面介绍了台网的建设与应用