Study on Effective Factors of City Residential Demand in China: Case Study of Xiamen City

住宅市场的发展是社会的热点问题，也是关系国计民生的重大问题，在目前住宅市场存在颇多争议的情况下，对影响我国城市住宅需求的因素进行研究更具有其理论和现实意义。 影响住宅需求的因素繁多复杂，而本研究落脚在中国城市住宅需求上，从一个宏观和中观的角度来展开研究，研究的对象确定为有效住宅需求，并包含消费需求和投资需求两大部分。影响城市住宅需求的因素包括人口因素、经济因素、区域城市因素、资本因素和政策因素，这些方面构成了一个比较完整的理论框架，为后续的实证分析奠定理论基础。 通过对我国31个城市样本所做的面板数据多元回归分析可以知道，我国城市住宅需求存在着明显的区位和城市差异，城市总体经济水平、人均经...The development of residential market are both the controversial problem in the society and the key point about the national economy and the people's livelihood which makes the study on effective factors of city residential demand in China much more significant. The effective factors of residential demand are various and complicated. Based on the Chinese cities, the study aims at effective reside...学位：经济学硕士院系专业：经济学院人口研究所_人口、资源与环境经济学学号：20042000

风险导向审计、内部控制与审计师行为——基于我国上市公司的实证检验

内部控制问题已经成为学界关注的热点。本文选取2007-2009年A股上市公司数据为样本,从审计收费和审计意见两个维度,考察了在风险导向审计下内部控制如何影响审计师的行为。从审计收费来看,内部控制较差的公司使审计师可能面临更大的审计风险,从而导致审计师要求增加风险溢价,进而提高审计收费。从审计意见来看,企业内部控制可以降低审计师审计失败的风险,进而鼓励审计师为内部控制较好的企业出具标准意见。实证结果发现:企业内部控制越好,越容易被收取更低的审计费用,表明内部控制可以影响审计师审计费用的收取;而且内部控制越好的企业,就越容易被出具标准审计意见,表明内部控制可以影响审计师审计意见的出具

Analysis on 6 Cases of Adverse Drug Reactions Induced by Ammonium Chloride and Licoricl Oral Solution

目的：探讨氯化铵甘草口服溶液不良反应的特点,为临床安全用药提供参考。方法：对本院2014年1月-2016年3月上报的6例氯化铵甘草口服溶液不良反应监测报告进行回顾性分析,对6例患者的年龄、性别、原患疾病,药物使用情况,ADR发生时间、临床表现、治疗与转归,ADR的类型与关联性评价等项目进行统计分析。结果：氯化铵甘草口服溶液不良反应多发生于老年患者;发生时间主要在用药8h内;以累及系统呼吸系统和皮肤为主;6例患者均痊愈,未出现后遗症或导致死亡。6例ADR中一般的ADR 2例,新的一般的ADR 2例,新的严重ADR 2例;关联性评价为可能4例,很可能2例。结论：临床上应重视氯化铵甘草口服溶液的不良反应,应密切观察患者,保证用药安全。Objective： To explore the characteristics of the adverse drug reactions （ADRs） induced by ammonium chloride and licoricl oral solution, to provide the reference for clinical safe medication and prevent adverse reaction. Methods：Restrospectively analysis were used on the ADRs reports of 6 cases of ammonium chloride and licoricl oral solution form January 2014 to March 2016 in our hospital. The application of drug, the age and gender distribution of patients ,occurrence time of ADRs, clinical manifestations ; treatment and outcome ; types and relevance evaluation of ADRs were analyzed respectively. Results：ADRs were mostly happened in the senile patients 8h after the medication. The clinical manifestations were respiratory and skins. 6 patients were all recovered, no occurrence sequel or lead to death. There were 4 cases of new ADR ,4 cases of commom ADR and 2 cases of severe ADR, 4 cases of possible relevance and 2 cases of probale relevance. Conclusion：The ADRs caused by ammonium chloride and licoricl oral solution should be pay more attention to, observed the changes closely to ensure clinical safe mediation

Composite microparticles of ibuprofen/lipid generated by supercritical fluids from their melts

采用CO2及N2辅助的气体饱和溶液微粒形成技术制备布洛芬/肉豆蔻酸、布洛芬/三棕榈酸甘油酯复合微粒,考察它们的形态、颗粒分布以及复合微粒中药物的溶出情况。N2辅助过程制得的布洛芬(质量分数5%)/肉豆蔻酸复合微粒与用该过程得到的纯肉豆蔻酸大小及粒径分布大致相同,而CO2辅助过程制得的布洛芬/肉豆蔻酸复合微粒却要比该过程得到的纯肉豆蔻酸的粒径要大,分布也较宽;CO2及N2辅助形成的布洛芬/肉豆蔻酸复合微粒无缓释效果。用N2辅助制备得到的含20%布洛芬(质量分数)的复合微粒保持了三棕榈酸甘油酯微粒化后的颗粒形貌,粒径更大;用CO2辅助制备得到的含20%布洛芬的复合微粒其粒径比三棕榈酸甘油酯微粒化后的颗粒粒径要小,粒径分布更窄;布洛芬/三棕榈酸甘油酯复合微粒具有缓释效果,而且用N2辅助制备的布洛芬含量为5%的复合微粒比布洛芬含量为20%的复合微粒溶出慢。Using the CO2-assisted and N2-assisted atomization processes,ibuprofen/lipid composite microparticles can be produced;the lipid includes myristic acid(MA) and tripalmitin(TP).The ibuprofen(5% in mass ratie)/MA composite microparticles show similar particle sizes to that of pure MA from the N2-assisted process,while the composite microparticles have a large particle size and particle size distribution,compared to that of pure MA from the CO2-assisted process.The dissolution reveals no controlled release of ibuprofen for the ibuprofen/MA composite microparticles either from the N2-assisted process or from the CO2-assisted process.For the ibuprofen/TP system,the obtained composite microparticles containing 20%(in mass) ibuprofen show similar particle morphology,while has a larger particle size(PS) than that of the pure myristic acid particles in the case of N2-assisted process.Nevertheless,the microparticles from the CO2-assisted process has a small PS and narrow PSD,compared to that of the pure myristic acid particles.The obtained ibuprofen/TP composite microparticles containing 5% or 20% ibuprofen show an evidently controlled drug release.For example,the drug release is only 20% in 500 min for the ibuprofen/TP microparticles containing 20% ibuprofen,prepared by the CO2-assisted process.国家自然科学基金资助项目(20406015);; 福建省新世纪优秀人才支持计划;; 福建省自然科学基金资助项目(2007J0167

Preparation of Tripalmitin Micronization by Supercritical Fluids Technique

利用气体饱和溶液微粒形成技术实验装置,分别用超临界n2和超临界CO2制备三棕榈酸甘油酯微粒,探讨压力、温度以及喷嘴大小等工艺参数对微粒(粒径、粒径分布和形貌)的影响。结果表明:n2辅助过程得到的微粒基本为球状;预膨胀压力越高,粒径越小,粒径分布越窄;100μM喷嘴下制得的微粒粒径最小,且分布较均匀。CO2辅助过程得到的微粒部分为球状,部分为针状和片状;预膨胀压力越高,粒径越小,粒径分布越窄;喷嘴直径大小对微粒平均粒径及粒径分布影响不大;预膨胀温度升高,颗粒的粒径稍微增大。CO2辅助过程得到的微粒粒径比n2辅助过程得到的微粒粒径稍大,但两者的粒径分布相差不大。Generation of tripalmitin microparticles from its melts was investigated by using both supercritical CO2 and supercritical N2.The effects of various operating conditions,such as the pre-expansion pressure,pre-expansion temperature,and nozzle size on the particle morphology,particle size and particle size distribution(PSD) were investigated.Results showed that microspheres were obtained from the N2-assisted process,the particle size decreased and PSD narrowed with the increasing of the pre-expansion pressure,nozzle size showed no obvious effect on the microparticles,and pre-expansion temperature should be less than 72 ℃ to obtain solid particles.From the CO2-assited process,spherical,lamellate and needle-like particles were obtained,the particle size decreased,PSD narrowed with the increasing of the pre-expansion pressure,nozzle size showed no obvious effect on the particles and the pre-expansion temperature slightly increased the average size of particles.Particles' PSD from supercritical CO2 was close to that from supercritical N2

Study on the Model both Cutting Variable-speed of the Log-core Veneer Lathe and Moving Locus Model with Constant-speed Peeling

详细分析了无卡轴旋切机的工作原理,推导了旋切过程中刀刃进给速度与圆木直径的数学模型,同时得出旋切时间的近似计算式。从中可知,旋切过程中刀刃进给速度必须按一定规律变化才能保证旋切机正常工作。建立了旋切机恒线速旋切的运动轨迹模型,推导出旋切机恒线速旋切时间的精确计算式,并在此基础上提出了旋切时间简便的近似计算式。这些研究结果均可用于指导设计和进行实际生产。Working principle of log-core veneer lathe had been analyzed in detail,and the mathematical model between the knife-carriage feeding speed and the diameter of the log core was established,in the meantime,the approximation cutting time formula was also derived.The feeding speed must be changed with continuousness and a rule,which can let the lathe work well.Moving locus model of invariable-speed peeling was also founded,precision calculating formula of invariable-speed peeling was deduced.In the same time,the simplification cutting-speed formula was also derived.These results of the research will provide a guide for the designing and the producing practice

死亡受体5胞外区域的重组、表达及活性鉴定

目的构建死亡受体5(deathreceptor5,DR5)胞外区域(eDR5)的表达载体,表达纯化重组蛋白并鉴定其生物特性。方法通过重叠PCR获得DR5胞外段编码序列,构建pET-22b(+)/DR5表达载体,转化大肠杆菌BL21(DE3),IPTG诱导表达,Ni2+柱亲和纯化,SDS-PAGE、直接ELISA鉴定纯化产物的纯度和特异性,用MTT法检测eDR5蛋白阻断DR5单克隆抗体FMU1.5和TRAIL诱导人胶质瘤细胞株U343(高表达DR5)、U373(低表达DR5)细胞凋亡的作用。结果获得了DR5胞外段编码序列,目的蛋白在上清及包涵体中都有表达,表达量占菌体总蛋白的30%以上,纯化的重组蛋白纯度达95%以上,蛋白产量达9mg/ml。ELISA结果表明所纯化蛋白为eDR5。eDR5蛋白可部分阻断FMU1.5和TRAIL诱导人胶质瘤细胞株U343细胞凋亡的作用,其阻断率与DR5表达相关。结论死亡受体5胞外段基因的成功重组、表达及纯化,为进一步的功能研究奠定了基础

A Study on the mechanisms of eutrophication of a shallow upstream lake in the Jiulong River Catchment

基于对九龙江上游龙潭湖富营养化水体和沉积物现状的监测结果,通过与国内富营养化深水湖库和流域下游大型富营养化浅水湖泊进行对比,深入探讨了流域上游浅水湖泊富营养化发生的原因及主导机制.流域上游浅水湖泊具有外源污染物输入较少的特点,较下游大型浅水湖泊更易受温度等气候条件和沉积物氧化还原状态的影响,以及外源输入总磷控制具有较强的滞后效应,因此对流域上游浅水湖泊富营养化的控制必须重视内源营养盐释放,特别是结合态磷的内源释放问题.Based on site monitoring chemical data of lake water and sediments during an algal bloom in the Longtan Lake,causes and mechanisms of eutrophication in shallow upstream lakes were discussed by comparing the Longtan Lake in upstream of the Jiulong River with deep eutrophic lakes and large shallow downstream eutrophic lakes in China.The shallow upstream lake is characterized as relatively simple nutrient inputs and high susceptivity to climatic variability(such as temperature),redox conditions,and strong lag effects of the external total phosphorus inputs.Therefore,attention must be paid to the sediments nutrient releases,especially,the bound phosphorus of sediments when remediating eutrophication in shallow upstream lakes.国家自然科学基金资助项目(41175130);教育部新世纪优秀人才支持计

高粱子粒淀粉表面色素的树脂分离研究

对纯化高粱淀粉过程中所得到的淀粉共生天然色素进行了树脂分离纯化研究。得到了树脂分离高粱淀粉共生色素的吸附动力学结果,3 种大孔吸附树脂 HPD-600、AB-8、H103 对高粱红的吸附为慢速平衡型。通过对树脂分离所得色素成份的红外光谱、紫外光谱、质谱分析得出,高粱籽粒淀粉共生色素与高粱壳中的高粱红主要成份是同样的物质,鉴定出所分离的主要成份之一为 5,7,4′-三羟基黄酮