403 research outputs found

    Reservoir-forming by lateral supply of hydrocarbon: A new understanding of the formation of Ordovician gas reservoirs under gypsolyte in the Ordos Basin

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    AbstractThere developed thick gypsum-salt strata in the Lower Paleozoic Ordovician in the Ordos Basin, particularly gypsum-salt in the 6th segment of the 5th member of Majiagou Fm (O1m56) in a wide distribution, serving as a good regional cap. Recent drilling and relevant studies have proven that the hydrocarbon-generating capacity of the marine-facies hydrocarbon source rocks under the Ordovician salt layers in the eastern Basin is poor on the whole, making it difficult to form ”self-generating and self-preserving type” commercial gas reservoirs under the salt layer in Mizhi salt subsag. However, further research on reservoir-forming conditions under the gypsolyte on the west side of the salt subsag indicates that the O1m57 – O1m510 strata near the east side of the palaeo-uplift contact directly with the Upper Paleozoic coal measure source rocks, forming a “hydrocarbon supply window”; the Yanshan Movement caused the tectonic inversion of the basin main body, resulting in the tectonic framework “high in the east and low in the west”, which is conductive to the further migration of natural gas generated by the Upper Paleozoic coal measures to the updip high position of the east side along the O1m57 – O1m510 carrier beds after entering the dolomite reservoir under the gypsolyte through the “hydrocarbon–supply window”. In addition, the facies changes in the dolomite rocks under the gypsum-salt provide favorable barrier condition for the regional gathering of natural gas. Therefore, it is concluded through comprehensive analysis that reservoirs may form beneath the Ordovician gypsolith in the central region of the basin on the west side of the salt subsag with hydrocarbon supplied from the Upper Paleozoic source rocks of coal measures, which is expected to open up a new situation of natural gas exploration under the Ordovician gypsum-salt layer in the Ordos Basin

    A Perplexing Case of a DUOX2 Mutation and Graves’ Disease

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    It is commonly accepted that DUOX2 mutations may cause congenital hypothyroidism and thyrotropin resistance, thus its combination with Graves' disease would be unusual. In this case, our patient's serum thyroid function tests suggested a high probability of thyroid hormone resistance syndrome, but genetic testing did not suggest gene mutations of THRα or THRβ. This is a rare case report of thyroid hormone resistance

    Identification of multi-drug resistant genes in P. aeruginosa isolates from patients under mechanical ventilation and respiratory support in an intensive care unit

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    Purpose: To determine multi-drug resistant (MDR) and metallo β-lactamase (MBL)-resistant genes from Pseudomonas aeruginosa isolated from intensive care unit (ICU) patients under mechanical ventilation and respiratory support.Methods: P. aeruginosa was isolated from 387 purulent tracheobronchial secretions collected from ICU patients who were intubated and mechanically ventilated for at least 48 h. Antibiotic resistance was determined by minimum inhibitory concentration (MIC) assay while MDR genes, viz, blaTEM, blaOXA, blaVIM, blaCTX-M-15 were determined by polymerase chain reaction (PCR).Results: A total of 144 (37.2 %) P. aeruginosa were isolated from the purulent tracheobronchial secretions. A majority of the isolates (51.4 %) were resistant to gentamicin. Meropenem-gentamicin was the predominant (35.4 %) resistant combination. Out of the 144 isolates, 102 (70.8 %) were positive for blaTEM gene, 51 (35.4 %) for were positive for blaOXA gene, 22 (15.3 %) were positive for blaVIM gene, while 19 (13.2 %) were positive for blaCTX-M gene.Conclusion: The high prevalence of MDR P. aeruginosa indicates the need for continued monitoring of MDR P. aeruginosa especially in ICU patients who are under mechanical respiratory support.Keywords: Multi-drug resistance genes, Mechanical ventilator, Respiratory support, Pseudomonas aeruginos

    DNA Checkpoint and Repair Factors Are Nuclear Sensors for Intracellular Organelle Stresses-Inflammations and Cancers Can Have High Genomic Risks.

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    Under inflammatory conditions, inflammatory cells release reactive oxygen species (ROS) and reactive nitrogen species (RNS) which cause DNA damage. If not appropriately repaired, DNA damage leads to gene mutations and genomic instability. DNA damage checkpoint factors (DDCF) and DNA damage repair factors (DDRF) play a vital role in maintaining genomic integrity. However, how DDCFs and DDRFs are modulated under physiological and pathological conditions are not fully known. We took an experimental database analysis to determine the expression of 26 DNA D

    A Review of the Role of Natural Clay Minerals as Effective Adsorbents and an Alternative Source of Minerals

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    The minerals with unique properties such as natural clay minerals (NCMs) have promising approach in environmental and industrial sphere. In fact, under some specific conditions the NCMs could be used either as effective adsorbent material or alternative source of minerals. This chapter presents an outline of a general review of factors that affect the application ability of NCMs and a descriptive analysis of NH4+ and REE adsorption behavior and extraction of rare earth elements (REE) by an ion-exchange with NH4+ ions onto NCMs. Clays and NCMs both effectively remove various contaminants from aqueous solution and serve as alternative sources of minerals, as extensively discussed in this chapter. This review compiles thorough literature of current research and highlights the key findings of adsorption (NH4+ and REE) that use different NCMs as adsorbents or alternative sources of minerals (i.e., REE). The review confirmed that NCMs excellently remove different cations pollutants and have significant potential as alternative source of REE. However, modification and further development of NCMs applications for getting the best adsorption and the best extraction of REE onto NCMs, which would enhance pollution control and leaching system is still needed

    A lightweight deep learning model for ocean eddy detection

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    Ocean eddies are typical oceanic mesoscale phenomena that are numerous, widely distributed and have high energy. Traditional eddy detection methods are mainly based on physical mechanisms with high accuracy. However, the large number of steps and complex parameter settings limit their applicability for most users. With the rapid development of deep learning techniques, object detection models have been broadly used in the field of ocean remote sensing. This paper proposes a lightweight eddy detection model, ghost eddy detection YOLO (GED-YOLO), based on sea level anomaly data and the “You Only Look Once” (YOLO) series models. The proposed model used ECA+GhostNet as the backbone network and an atrous spatial pyramid pooling network as the feature enhancement network. The ghost eddy detection path aggregation network was proposed for feature fusion, which reduced the number of model parameters and improved the detection performance. The experimental results showed that GED-YOLO achieved better detection precision and smaller parameter size. Its mAP was 95.11% and the parameter size was 22.56 MB. In addition, the test experiment results showed that GED-YOLO had similar eddy detection performance and faster detection speed compared to the traditional physical method
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