Ecological effect assessment of marine pollution

加拿大国际发展署“UPCDTier-1之Community basedConservationManagement”项目(01843 S53305);; 国家自然科学基金项目 (4031049) ;; 福建省自然科学基金项目(D031002

Cumulative impact assessment on coastal engineering:a case study of the Xiamen Western Sea

国家自然科学基金项目 (40371049

钯纳米粒子体系中的近场耦合与SERS效应

利用广义米氏散射理论(gEnErAlIzEd MIE)从理论上系统研究了球形钯纳米粒子二聚体的线性光学性质及其表面增强拉曼散射效应.计算表明,粒子间的近场耦合效应对粒子对的吸收、散射和消光光谱影响显著,其表面等离子体激元共振峰的位置随粒子间隔的变小而显著红移.在耦合效应和尺寸效应的共同作用下,钯纳米粒子二聚体中“热点“位的最大SErS增强因子可达到107~108,表面平均SErS增强因子可达105~106.通过对远场和近场的对比研究,发现消光谱与粒子间的近场增强谱的谱型大致相同,但消光谱的极值峰位与SErS的最大增强峰位之间存在一定的偏离,这显示了表面等离子激元共振对远场和近场的不同影响,我们对此进行了讨论.相关结果对揭示远场与近场的关联性及探索过渡金属体系中表面增强散射的电磁场增强机理有较重要的科学意义.国家自然科学基金(20703032);国家重点基础研究发展计划(2009CB930703);福建省自然科学基金(E0710028)资助项

低浓度三氯乙烯诱发L-02 肝细胞蛋白质组异常表达

【: 目的】研究低剂量三氯乙烯对人 L-02 肝细胞蛋白质表达谱的影响, 以助于阐明三氯乙烯引起细 胞早期应答反应的分子机制。【方法】L-02 肝细胞暴露于低剂量( 3 μmol/L) 三氯乙烯24 h 后, 提取细胞总蛋 白, 双向电泳分离蛋白质, 软件分析凝胶图像, 基质辅助激光解吸电离飞行时间串联质谱(MALDI-TOF-TOFMS) 对相关异常变化斑点进行鉴定。【结果】和对照组比较, 低剂量三氯乙烯处理后L-02 肝细胞蛋白质表达发 生改变, 初步鉴定出7 个差异蛋白。低剂量三氯乙烯刺激后, 上调的蛋白有核糖体样蛋白( similar to ribosomal protein) 和SET protein, 下调的蛋白有异柠檬酸脱氢酶( isocitrate dehydrogenase, NADP) 和腺苷二磷酸- 核糖基 化因子鸟苷酸因子6 ( ADP-ribosylation factor guanine nucleotide factor 6) , 微管- 肌动蛋白交叉连接因子1 (microtubule-actin crosslinking factor 1) 特异表达, 肽基脯氨酰顺- 反异构酶PPI ( peptidyl prolyl cis/trans isomerase) 缺失。【结论】低剂量的三氯乙烯处理后, L-02 肝细胞中的蛋白表达谱发生明显变化, 这为三氯乙烯 毒作用机制的进一步研究提供了线索

Real-space imaging with pattern recognition of a ligand-protected Ag374 nanocluster at sub-molecular resolution

厦门大学化学化工学院郑南峰教授团队长期致力于研究固体功能材料的表界面化学行为，在分子水平上实现对固体功能材料的化学性能的调控与优化。得益于固体表面物理化学国家重点实验室的多学科合作以及能源材料化学协同创新中心的多单位优势互补，郑南峰教授课题组通过与校内外多个课题组的密切合作，近期在功能材料的可控制备、复杂表界面结构的高分辨表征和表界面过程分子机制的深入理解等方面取得系列重要进展，相关成果近期均在Nature Communications发表。 针对纳米颗粒表面配体难被高分辨直接成像的特点，与厦门大学郑兰荪、谢兆雄等教授以及中科院大连化物所杨学明研究员、马志博副研究员和芬兰于韦斯屈莱大学HannuHäkkinen教授等多个团队紧密合作，在利用扫描隧道显微镜表征金属纳米团簇的表面配体层结构方面取得重要进展。以原子结构精确的 Ag374纳米团簇为研究对象，利用超高真空扫描隧道显微镜分别在液氦及液氮温度下获得了单个团簇亚分子高分辨率的拓扑图像。【Abstract】High-resolution real-space imaging of nanoparticle surfaces is desirable for better understanding of surface composition and morphology, molecular interactions at the surface, and nanoparticle chemical functionality in its environment. However, achieving molecular or sub-molecular resolution has proven to be very challenging, due to highly curved nanoparticle surfaces and often insufficient knowledge of the monolayer composition. Here, we demonstrate sub-molecular resolution in scanning tunneling microscopy imaging of thiol monolayer of a 5 nm nanoparticle Ag374 protected by tert-butyl benzene thiol. The experimental data is confirmed by comparisons through a pattern recognition algorithm to simulated topography images from density functional theory using the known total structure of the Ag374 nanocluster. Our work demonstrates a working methodology for investigations of structure and composition of organic monolayers on curved nanoparticle surfaces, which helps designing functionalities for nanoparticle-based applications.The experimental work done in Dalian Institute of Chemical Physics (DICP), Chinese Academy of Sciences, was supported both by Xiamen University (The National Key R&D Program of China grant 2017YFA0207302, National Natural Science Foundation of China, grant 21731005, 21420102001 and 21721001 the National Key R&D Program of China grant 2017YFA0207302) and DICP (National Natural Science Foundation of China grant 21688102, the Strategic Priority Research Program of Chinese Academy of Science, grant XDB17000000, the National Key Research and Development Program of the MOST of China, grant 2016YFA0200603 and the open fund of the state key laboratory of molecular reaction dynamics in DICP, CAS, grant SKLMRD-K201707). Q.Z. thanks Dr. Huayan Yang for providing the samples for STM imaging. S.M. and H.H. thank T. Kärkkäinen and P. Nieminen for discussions on pattern recognition algorithms. The theoretical and computational work in the University of Jyväskylä was funded by the Academy of Finland (grants 294217, 315549, AIPSE program, and H.H.’s Academy Professorship). H.H. acknowledges the support from China’s National Innovation and Intelligence Introduction Base visitor program. S.K. thanks the Vilho, Yrjö, and Kalle Väisälä Foundation for the grant for doctoral studies. The DFT simulations were done at the Finnish national supercomputing center CSC and at the Barcelona Supercomputing Center (PRACE project “NANOMETALS”). 研究工作得到了科技部、国家自然科学基金委和教育部，中科院先导项目，国家重点研发计划，分子反应动力学国家重点实验室开放课题基金等项目的资助

Freestanding palladium nanosheets with plasmonic and catalytic properties

通讯作者地址: Huang, XQ (通讯作者), Xiamen Univ, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R China 地址: 1. Xiamen Univ, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R China 2. Xiamen Univ, Dept Chem, Coll Chem & Chem Engn, Xiamen 361005, Peoples R China 3. Xiamen Univ, Dept Phys, Xiamen 361005, Peoples R China 电子邮件地址: [email protected] metal films can exhibit quantum size and surface effects that give rise to unique physical and chemical properties(1-7). Metal films containing just a few layers of atoms can be fabricated on substrates using deposition techniques(7), but the production of freestanding ultrathin structures remains a significant challenge. Here we report the facile synthesis of freestanding hexagonal palladium nanosheets that are less than 10 atomic layers thick, using carbon monoxide as a surface confining agent. The as-prepared nanosheets are blue in colour and exhibit a well-defined but tunable surface plasmon resonance peak in the near-infrared region. The combination of photothermal stability and biocompatibility makes palladium nanosheets promising candidates for photothermal therapy. The nanosheets also exhibit electrocatalytic activity for the oxidation of formic acid that is 2.5 times greater than that of commercial palladium black catalyst.NSF of China 20925103 20871100 20721001 20703032 MOST of China 2009CB930703 2011CB932403 Fok Ying Tung Education Foundation 121011 NSF of Fujian 2009J06005 Key Scientific Project of Fujian Province 2009HZ0002-

改良分子信标-双重实时荧光PCR快速检测SARS病毒

目的建立改良分子信标-双重实时荧光PCR检测SARS病毒的方法,用于SARS的早期诊断和动物溯源。方法利用改良分子信标技术、装甲RNA和双片段双色荧光技术,根据GenBank公布的SARS病毒聚合酶基因1b的阅读开放框架结构的保守序列,自行设计一对引物和探针,以部分临床标本的酶联吸附实验结果和传统细胞培养方法作为对照,建立分子信标检测SARS病毒的方法。对368份临床标本(咽漱液、血液、粪便、尿液)、52份细胞培养液和50份动物标本进行荧光PCR扩增。结果分子信标检测SARS病毒的方法灵敏度为10～100个拷贝ml,与流感病毒等呼吸道病毒无交叉反应。分子信标检测368份临床标本,20份阳性。其中确诊病例阳性率为21.27%(1047),确诊病例的咽漱液阳性率为43.48%,还分别从粪便和血清中检测到SARS病毒。52份细胞培养液,29份阳性,阳性率为55.77%。50份动物标本,23份阳性,阳性率为46%。结论改良分子信标-双重实时荧光PCR检测SARS病毒方法灵敏度高、特异性强,可用于SARS的临床早期诊断和动物溯源

第十八届美国理论与应用力学大会总结

1会议概况2018年6月5—9日,第18届美国理论与应用力学大会(18th U.S. National Congress of Theoretical and Applied Mechanics, USNCTAM2018)在美国芝加哥召开.本次大会由美国力学国家委员会和中国力学学会联合主办,旨在探讨和交流近四年世界范围内在理论和应用力学领域的基础研究、创新技术的最新进展,吸引了来自世界各地的近千名专家学

The Countermeasures and Suggestions Based on Social Economic Contribution and Ecological Environment Influence of Sea Reclamation

沿海地区是我国面向东南亚、中亚、中东等地区重要的经贸文化交流窗口,是我国"一带一路"战略的重要枢纽。随着沿海地区的快速城市化,用地需求逐渐增加,填海造地是解决这一问题的重要途径。文章论述填海造地的社会经济效益及其生态环境影响;在此基础上对填海造地的综合损益研究进行分析,提出加强填海造地社会经济效益的量化研究、探索填海造地社会经济效益与生态环境影响的权衡研究、关注填海造地的海岸带社会生态系统稳定性研究等3个未来研究趋势;最后针对目前填海造地管理提出对策及建议,以期为我国海岸带绿色可持续发展提供依据。Coastal areas are important windows for China's economic,commercial and cultural communication with Southeast Asia,central Asia and Middle East areas,which are the core regions for"One Belt and One Road"national strategy.With the rapid development of coastal urbanization,the sea reclamation is becoming an indispensable means to meet the demand for landuse.This paper is an overview about social economic contribution of sea reclamation.Meanwhile,the ecological environment impact of sea reclamation was discussed in detail.Then,based on the research of comprehensive profit and loss of sea reclamation,three constructive suggestions were proposed,as increasing the quantitative research on social economic contribution,exploring the research on trade-off between social economic contribution and ecological environment impact,and focusing on the stability of social-ecosystem in the future.Four countermeasures and suggestions for sea reclamation were also proposed to provide theoretical references for the green sustainable development of coastal cities.国家海洋局海洋咨询中心-厦门大学联合研究项目“我国典型沿海大城市围填海生态影响评估及总量控制技术研究