Effects of electro-acupuncture at stomach meridian acupoints on serum and urine metabolic profiles of gastric ulcer model rats

目的:采用核磁共振氢谱技术(1H NMR)研究电针胃经穴对胃溃疡模型大鼠血清和尿液代谢轮廓的影响。方法:40只SD大鼠随机分为空白组、模型组、胃经穴组和胆经穴组,每组10只。除空白组外,利用束缚冷应激法制备大鼠胃溃疡模型,造模成功后用电针分别刺激胃经组和胆经组相关穴位,收集大鼠的血清和尿液,获取一维1H NMR谱,并利用模式识别方法分析各组间的代谢轮廓差异。结果:与模型组比较,胃经穴组血清中的肌醇、甘氨酸、谷氨酰胺、异亮氨酸、缬氨酸和尿液中的肌酸酐、乳酸、醋酸盐、肌酸、琥珀酸盐、牛磺酸、甘氨酸、苯乙酰甘氨酸、尿囊素、胆碱、三甲胺、甲酸盐、甜菜碱代谢物的表达水平得到了明显地恢复(P<0.05),更接近空白组的代谢水平。结论:电针胃经穴可通过调节胃溃疡大鼠的氨基酸代谢和脂肪代谢促进胃黏膜损伤的修复。Objective: To explore the effects of electro-acupuncture at stomach meridian acupoints on serum and urine metabolic profiles of gastric ulcer model rats by application of 1H nuclear magnetic resonance(1H NMR) spectroscopy. Methods: Forty SD rats were randomly divided into the control group, model group, stomach meridian group and gallbladder meridian group, with 10 rats in each group. The gastric ulcer rat model was established by the restrained cold stress method. After modeling, the model rats were treated with electro-acupuncture at the stomach meridian and gallbladder meridian respectively, the serum and urine of rats were collected to obtain one dimensional 1H NMR spectrum, and the differences of metabolic profiles between these groups were analyzed by the pattern recognition method. Results: Compared to model group, the concentration of myo-inositol, glycine, glutamine, isoleucine, valine in serum from the stomach meridian group have obviously recovered and returning to normal level. The urinary metabolites such as Creatinine, lactic acid, acetic acid salt, acid, succinic acid salt, taurine, glycine, phenylacetyl glycine, allantoin, choline, trimethylamine, formate, betaine have also partly recovered after electro-acupuncture stimulation in the stomach meridian(P<0.05). Conclusion: Electro-acupuncture at stomach meridian acupoints could repair the gastric ulcer lesion by regulating the metabolism of lipid and amino acid in rats with gastric ulcer.国家自然科学基金项目(No.81473751,No.81260556);; 广东省自然科学基金项目(No.2014 A030313005);; 福建省自然科学基金项目(No.2015J05168);; 福建省卫生厅科研项目(No.wzpw201301)~

设有平板状导流板的圆筒式节能收水器

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设有平板状导流板的圆筒式收水器

本发明涉及一种设有平板状导流板的圆筒式收水器，包括一圆柱筒，圆柱筒内安装一对其直线边交叉放置的由直线边和椭圆弧形边组成的导流板，导流板与湿空气流的流动方向的夹角为9.5°-79.3°，导流板的椭圆弧形边与圆柱筒筒壁接触；圆柱筒下端安装有上端为圆形下端为方形的底座；圆柱筒上端安装具有厚度的其截面为方形格栅的整流罩；整流罩中方形格栅的网格边长为圆柱筒直径为5-15%；底座高为圆柱筒直径的1/10-7/10；圆柱筒高与整流罩高之和为圆柱筒直径的1-5倍；该收水器还可进一步包括其截面呈蜂窝状排列的圆柱筒组；本发明的收水器结构简单，使用方便，经济有效，而且收水效率可比波纹收水器的收水效率提高20-45%

中国植物应答环境变化研究的过去与未来

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