Tributyltin and bisphenol A induce polycystic ovarian syndrome and its mechanisms involved

多囊卵巢综合征（polycysticovariansyndrome,PCOS）是以稀发排卵或无排卵、高雄激素或胰岛素抵抗、多囊卵巢为特征的内分泌紊乱的症候群，复杂且具有异质性，是婚育年龄妇女中最常见的内分泌紊乱疾病。PCOS的病因较为复杂，已有研究证明类雌激素化合物双酚A暴露（bisphenolA,BPA）与PCOS的发病有关，说明环境中的内分泌干扰物与PCOS发病存在一定的联系。 本研究以大鼠为实验动物模型，以三丁基锡（tributyltin,TBT）作为类雄激素化合物的典型代表，探究TBT（10ng/kg/d、100ng/kg/d）能否诱导PCOS相关症状，同时以BPA（50μg/kg/...Polycystic ovarian syndrome (PCOS) is the most common endocrine abnormality in reproductive-age females, characterized by hyperandrogenaemia, insulin resistance, chronic anovulation and cystic follicles. The potential influence of environmental endocrine disrupting chemicals on the development of PCOS has been suggested because some studies have revealed that bisphenol A (BPA) could induce PCOS. ...学位：理学硕士院系专业：生命科学学院_动物学学号：2162012115229

Design and Implementation of Network Security Service Management System in Data Center

随着我国企业信息化的深入，企业对信息系统高度依赖。由于企业规模不断扩大，越来越多的大型跨区域企业、集团都建立了自己的业务网络和数据中心用于运行和支撑企业核心业务。与此同时，各种信息安全威胁层出不穷，对企业的网络安全防护提出了新的挑战。这在充分体现网络安全支撑重要性的同时，对网络安全管理的稳定和高效均带来了巨大的压力。很多企业都基于数据中心构建了企业网络安全防护体系，其中包括管理和技术两个层面，正如信息安全领域中经常提到的，信息安全“三分靠技术，七分靠管理”。仅仅靠在信息安全防护设备方面进行投入，并不能保障企业的信息安全，缺乏有效的信息安全管理才是目前企业信息安全体系运行保障的瓶颈。 本文尝试...With the development of the enterprise informationization, enterprises depend heavily on Information System in our country. With the continuous expansion of the scale of enterprises, more and more large multinational enterprises and groups have constructed their own business network and information-processing centre for operating and supporting their core business. At the same time, various threat...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X200923028

粉煤灰颗粒的微观分类探讨

鉴于目前关于粉煤灰颗粒的微观分类没有一个普遍、清晰、浅显的分类方法,且术语不够统一的情况,为方便学术交流提出了一个新的较普遍、清晰、浅显的原状粉煤灰颗粒分类方法,使粉煤灰颗粒微观分类方法更加完善

Research on the Advent of Managed Accoount & the Propability of Tunneling of Mutual Funds

专户理财的出现已成为业界关注的焦点,其中投资者最为担忧的是基金管理公司利用公募基金为专户理财进行的利益输送。从公募基金与专户理财的区别入手,结合现有关于利益输送的研究成果,认为如果防范措施不到位,利益输送行为是很可能出现的。The advent of managed account has been the focus of fund industry attention,however,the probability of mutual funds company using public mutual funds to subsidize the managed account becomes the investors anxiety.This paper compares the difference between the pubulic funds and managed account,combining the present literature on tunneling and draw the conclusion that if there are not proper measures,the probability of tunneling is very high

Low Power 13 b 100 MS/s Sample and Hold Circuit

采用TSMC0.18μM1P6M CMOS工艺设计了一种高性能低功耗采样保持电路。该电路采用全差分折叠增益自举运算放大器和栅压自举开关实现。在3.3V电源电压下,该电路静态功耗仅为16.6MW。在100MHz采样频率时,输入信号在奈奎斯特频率下该电路能达到91db的Sfdr,其有效精度可以达到13位。A high performance low power sample and hold circuit is designed based on TSMC0.18 μm 1P6M CMOS technology.In this circuit,a fully differential folded gain-boosted operational amplifier and bootstrapped switch is employed to meet the requirements.The circuit consumes only 16.6 mW static power with 3.3 V power supply,it can attain 91 dB SFDR when the input signal at Nyquist frequency with sampling rate of 100 MS/s,of which the effective number of bit(ENOB)can reach to 13 b

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中药是我国传统医学的重要组成部分,但部分中药存在成分复杂、水溶性差等问题,给临床前研究,尤其是体外药效学研究带来困扰。本文就目前体外药效学研究中难溶性中药或中药成分增溶方法或技术进行综述,探讨其可行性及对中药药效行为的影响。福建省自然科学基金项目（2015J01491

Application of Complex Three-Order Cumulants to Fault Diagnosis of Hydraulic Valve

为了提高故障诊断正确率,提出了一种基于复数三阶累积量的机械故障诊断方法.三阶累积量的不同定义的复数形式包含了信号间不同的耦合信息,利用这些信息进行了故障诊断.在溢流阀故障诊断实验中,利用这些不同的耦合信息,通过二维小波在不同的方向上对故障信号和正常信号进行特征提取,然后将这些特征值输入支持向量机进行故障判别.实验结果表明,上述方法可以提高故障诊断正确率.同时还对实数三阶累积量也进行了相同的实验,这些实验所取得的诊断效果证明了采用本文方法的有效性.In order to improve the correction rate of fault diagnosis,one method of mechanical fault diagnosis based on complex three-order cumulants was proposed.The complex forms with different definitions of three-order cumulants included different coupling information of signals,which was used to diagnose fault.In the experiment on the fault diagnosis of overflow valve,using the different coupling information,the features of fault signals and normal signals were extracted by 2-D wavelet in different directions,and then they were input into support vector machine to diagnose the fault.The experiment results show that this method can improve the correction rate of diagnosis.Furthermore,the same experiment was performed on the real three-order cumulants,and the results verify the effectiveness of the method proposed in this paper.国家自然科学基金资助项目(50975098

突发事件中医疗救援队伍的全方位心理支持措施

突发事件是指包含自然灾害、公共卫生事件等在内的造成严重社会危害，需要应急应对的事件。医疗救援队伍是突发事件的主力救援队伍，他们在进行救援任务的同时，由于救援环境不适应，防护物资不足、过度工作等原因，身心都承受着巨大的压力，常出现恐惧、紧张、焦虑、悲观、自责，甚至出现急性应激障碍。若得不到及时有效的心理支持，在事件结束后仍会遗留如创伤后应激障碍等长期的心理问题。全方位的心理支持包括救援全程的心理测量，救援前的队伍组建和详尽的心理支持干预培训，救援期间的自我放松、基本的生活和安全保障、药物治疗、在线心理援助和救援后的撤离应激源、重建生活方式等

等离子体射流及其发生器研究进展

等离子体射流是近年来学术界兴起的新型研究领域。文中阐述了等离子体射流的基本概念和分类以及其技术优势,并从电极结构和驱动电源分类上重点介绍了国内外等离子体射流发生器的研究现状和前景展望。福建省自然科学基金资助项目(2010J01014