Design and Implementation of Administration Business System for a Public Security Bureau

随着信息科学技术的飞速发展，办公自动化系统在技术和应用上都得到了更高层次的发展，人们逐渐意识到对办公管理系统的运用可以使日常办公工作更加方便、快捷和高效。随着公安信息化的飞速发展，应用信息化平台处理公安行政管理业务，实现科技强警，增强公安系统的快速反应、统一指挥、打击犯罪的能力，以及协调作战的能力，需要为市公安局建设一套行政管理信息系统，对公安日常行政管理工作提供更便捷，实现公安管理现代化和自动化。 本文结合公安局行政管理业务需要，对当前系统开发背景及意义进行研究，分析实际业务要求，并基于J2EE技术架构，选用Eclipse作为开发工具，后台数据库采用SQLSERVER2005，结合UML、...With the rapid development of information science and technology, office automation system in technology and applications have been a higher level of development, people gradually realize that to the use of office management system can make the daily office work more convenient, fast and efficient. With the rapid development of the public security information, application information system to dea...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X201323141

Design and Implementation of Performance Management System for a College

随着高校人事制度的改革不断深入，新的管理方式和新的管理制度的不断出现，高校人事管理部门面临了很多新的问题。目前很多高校都实行全员聘任制，并且对教师的评价机制也采用绩效考核管理和绩效工资管理的机制。绩效管理的实行增加了人事管理部门的工作量，因此，绩效管理中实行信息化是刻不容缓的事情。论文在充分考虑江西工业工程职业技术学院目前绩效管理的现状基础上，力求在学院绩效管理中实现信息化、无纸化和网络化管理，从而改进全院职工绩效管理的管理方式，提高绩效管理的工作效率。 系统在充分考虑学院目前的软硬件条件的基础上，以实际的业务流程作为基础，采用面向对象的设计方法，开发了绩效管理系统。论文首先介绍了江西工业工...With the deepening of the reform of personnel system in colleges, the new management mode and new management system constantly, the personnel management department in universities is facing many new problems. At present, many universities have implemented the full employment, and the evaluation mechanism of teachers also adopts the mechanism of performance appraisal management and salary managemen...学位：工程硕士院系专业：软件学院_软件工程学号：X201323222

Transition Metal-Catalyzed Amination / Oxidation of Ynamides for the Synthesis of 2H-Pyrroles / α- Functionalized Amides

近年来炔酰胺成为有机化学领域高度关注的研究热点之一。同时，炔酰胺化学也取得了很大的研究进展。炔酰胺分子中氮原子的供电子效应使得其碳碳三键高度极化，因而使得炔酰胺在反应过程中显示出较高的活性和优秀的区域选择性。 本论文研究结果包括三个部分：（1）金催化与路易斯酸催化的组合应用：2H-吡咯类化合物的简易合成方法研究；（2）锌催化的炔烃氧化反应来合成α-硫氰酸酯酰胺类化合物；（3）钪催化的炔烃氧化反应来合成α-烷氧基酰胺类化合物。 论文第一部分研究了金催化与路易斯酸催化的组合应用来合成多取代2H-吡咯类化合物。该反应的亮点在于：通过金催化与路易斯酸组合催化的异噁唑和炔酰胺的反应，以高收率得到了重...In recent years, ynamide has become one of the hotspots of organic chemistry. At the same time, ynamide chemistry has also made great progress. The electron-donating ability of the nitrogen of ynamide strongly polarizes the triple bond, which allows for exceptionally high levels of reactivity and regioselectivities. The research contents of this thesis include three parts: (1) combination of gol...学位：工学硕士院系专业：化学化工学院_化学工程学号：2062014115143

Association of APOE genotype with academic and physical education performance; The role of TREM2/DAP12 complex in microglial signaling pathway

载脂蛋白E（apolipoproteinE，apoE）是脑中主要的载脂蛋白及胆固醇运载体。人类APOE基因具有多态性，包含了APOEɛ2、ɛ3和ɛ4三种亚型。其中，ɛ4等位基因是引起晚发型阿尔茨海默病（Late-onsetAlzheimer’sDisease）最重要的危险因素。尽管许多研究表明在老年人中APOE基因的多态性与认知功能密切相关，但其对青少年群体认知功能的影响研究非常少，并且有限的研究结果存在争议性。为了进一步探讨APOE基因多态性对儿童认知功能的影响，我们招募了了571名10-12岁中国小学生，并对他们的APOE基因型与学科学习成绩进行相关...Apolipoprotein E (apoE) is a major apolipoprotein and a cholesterol carrier in the brain. Human APOE gene is polymorphic and it exists in three major isoforms: ε2, ε3, ε4. The ɛ4 allele is the strongest risk factor for late-onset Alzheimer’s disease. Although it has been widely recognized that APOE polymorphic alleles are associated with cognitive impairment in the elderly people, there have ...学位：理学硕士院系专业：医学院_微生物学学号：2452014115344

Study on Burma Chinese Chamber of Commerce (the early 20th century to the beginning of the 1960s)

本论文以缅甸华人商会作为研究对象，具体地讨论从20世纪初到60年代初，在祖籍地中国和缅甸社会的发展脉络下，缅甸华人商会成立的背景、经过及其发展状况，并探讨在不同的历史阶段，华人商会所面临的挑战和其在运作、功能等方面表现出的特点。缅甸华人商会的发展史，既是商人自身整合和社会、政治参与的写照，也蕴含着中缅两国历史变迁与转型的复杂变量。 华人移居缅甸自古有陆路和海路两种途径，两者分别被称之为“翻山华侨”和“渡海华侨”。前者构成当今缅甸云南华人之主体，其早期移民活动与传统中缅贸易的发展密切相关；后者构成了当今缅甸闽粤籍华人之主体，其成规模的移民活动则始于19世纪中叶英国对缅甸的殖民活动。至20世纪初...This paper takes the Burma Chinese Chamber of Commerce as the research object, specifically discusses the background, process and development condition of Burma Chinese Chamber of Commerce’s establishment under the development sequence of ancestral home China and Burma society from the early 20th century to the beginning of the 1960s, and investigates the challenges faced by Chinese Chamber of Com...学位：历史学博士院系专业：人文学院_世界史学号：1032013015404

Design and Implementation of Hotel Room Management System

现代交通工具的日益发达，人们生活物质水平的不断提高，工作出差、度假旅游也成为热点，宾馆已逐步承担起人民生活中不可或缺的重要角色。随着宾馆住宿人数的不断增加，宾馆的业务更加繁忙，工作量也逐渐加大。传统的人工管理方法存在着很多弊端：事务繁多、工作效率低；浪费人力物力财力；管理容易出现错误和混乱；难以提供决策的依据，难以提升宾馆的知名度和现代化形象。以往由人工进行管理的模式已不能满足现在消费者的需要，也没办法与高效、快速地处理经营中产生的大量信息数据的需要匹配。开发宾馆客房管理系统，提高宾馆服务质量和管理水平，提高宾馆的管理效率，有十分积极的现实意义和应用价值。 本文从宾馆客房管理的实际需要，对宾...With the development of modern vehicles and improvement of people's living, business trip and vacation travel has become a hot spot, hotel has became increasingly indispensable component in people's lives. With the increasing number of hotel accommodation, the hotel business is more and more busy and the workload is gradually increasing. There are many drawbacks of traditional manual management me...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X201323005

国際戦略提携におけるコントロールと信頼

　国際戦略提携のパートナーシップ・マネジメントには，コントロールと信頼という2つの基本アプローチがあるとされる。コントロールのアプローチは，目標を達成するため，特に相手の機会主義的な行動を抑制するための典型的なマネジメント手法として，従来からの研究対象とされてきている。信頼のアプローチは，企業の国際提携の普及が進むにつれて，特に日本や中国を始めとするアジア企業に対する研究が進むにつれて，多くの注目を集めている。しかし，信頼に対する理解が様々であり，コントロールと信頼の2つのアプローチに同時に焦点を当てる研究が少ない。本稿は，コントロールの具体的メカニズムを明確化した後，信頼の概念に対する理解を整理し，信頼構築の具体的方法を明らかにした。最後に，コントロールと信頼との関係は，それぞれ完全に独立的なものではなく，並列の概念と見なされる方が妥当であろうと結論づけた

Artemisinin and malaria: Current understandings of drug activation, action, and resistance

如能及早确诊并合理救治,疟疾是可以通过抗疟药来治愈的.然而,抗药性疟原虫通常在一种新型药物的大规模使用后的数年内就会出现.随着疟原虫几乎对所有类; 型的抗疟药均产生了不同程度的抗性,青蒿素类药物联合疗法(ACTs)也由此成为治疗疟疾最重要的手段.不幸的是,已有报道称在东南亚地区采用青蒿素或A; CTs治疗后出现了延迟原虫清除的现象,这也让研究者们对青蒿素及其衍生物治疗在未来发生完全失效的可能感到担忧.本文简要综述了青蒿素的药物激活、作用; 机理、药物靶点及可能的抗药性机制等研究的进展;对抗药性的定义、青蒿素组合用药中伴侣药物的选择,以及当前为消除疟疾采取全民用药的努力等问题作了讨论; .与此相关的议题已有大量的研究和文献报道,由于篇幅有限未能逐一列举.此外,本文所讨论的某些问题仍存争议、还需深入的研究方能解答.Malaria is a disease that can be cured with antimalarial drugs if; treated early and appropriately. However, parasites resistant to a new; drug generally emerge within a few years after large-scale applications.; Artemisinin (ART or Qinghaosu) combination therapies (ACTs) have become; the major treatments for malaria after the emergence of parasites; resistant to almost all classes of antimalarial drugs. Parasites with; delayed parasite clearance (DPC) after ART or ACT therapies have also; been reported in Southeast Asia, raising concerns of total failure of; ART and its derivatives. Many classes of antimalarial drugs have been; introduced to successfully treat malaria infections, including; chloroquine, piperaquine, primaquine, mefloquine (MQ), pyrimethamine,; sulfadoxine, ART and derivatives, etc. Regrettably, many of these drugs; have been abandoned by many countries in malaria endemic regions due to; the emergence of drug resistant parasites. According to World Health; Organization, parasite responses to a drug can be classified into four; categories (S, RI, RII, and RIII): Sensitivity (S) to a drug is defined; as clearance of asexual parasitemia within seven days of the first day; of treatment without recrudescence; Resistance RI is defined as; clearance of asexual parasitemia as in sensitive parasites, followed by; recrudescence; RII resistance is indicated by marked reduction of; asexual parasitemia, but no clearance; and RIII resistance shows no; marked reduction of asexual parasitemia. Currently, RII and RIII; resistance to chloroquine, pyrimethamine, and other drugs have been; widely reported; but residence to ART remains largely at R1 level. ART; resistance was initially defined as parasites with half parasite; clearance time (PC1/2)>5 h under a standard ART treatment regimen; (three-day artesunate treatment at 2-4 mg kg-1 d-1). A second; measurement is in vitro ring survival assay (RSA) that was developed; based on the observation that the ring stages of some parasite strains; could survive a short period of ART treatment. Another indicator of; increasing ART tolerance is the elevated rate of recrudescence after ART; or ACT treatments. The generation of highly reactive radicals via; endoperoxide cleavage is critical for ART activation. Both free ferrous; iron and heme have been proposed to be the predominant iron sources for; ART activation. The heme required for ART activation can be derived from; the parasite's heme biosynthesis pathway at the early ring stage and/or; from hemoglobin digestion at later stages. A large number of parasite; molecules have been found to bind or interact with ART, most notably the; Plasmodium falciparum ATPase 6 (PfATP6 or SERCA),; phosphatidylinositol-3-kinase (PfPI3K), chloroquine resistance; transporter (PfCRT), and multiple drug resistance 1 (PfMDR1). Recently,; a gene encoding a parasite Kelch protein (K13) with a six-blade; propeller domain was identified as a potential molecular marker of ART; resistance in vivo (DPC>5 h) and in vitro (RSA). Various antimalarial; drugs such as meflouine and piperaquine have been used as partner drugs; in ACTs. However, parasites resistant to these partner drugs have also; been reported, which may explain the reported slow parasite clearance; after ACT treatment. The success of ACTs in treating malaria infections; has generated optimism and proposals for malaria eradication by mass; drug administration (MDA), and successes have been achieved from several; studies. However, the impact of MDA on malaria transmission in the long; term, especially in low- and moderate-transmission settings, and the; potential consequences of developing drug resistance, requires careful; evaluation. There are a large number of studies and publications on; these related subjects, and it is impossible to include or cite all the; publications in this review. Additionally, some of the issues discussed; here are still being debated, requiring further investigation.国家自然科学基金; 国家外国专家局和教育部111计划; 美国国家过敏和传染病研究所项目资

Effects of wall temperature on boundary layer stability over a blunt cone at Mach 7.99

Effects of wall temperature on stabilities of hypersonic boundary layer over a 7-degree half-cone-angle blunt cone are studied by using both direct numerical simulation (DNS) and linear stability theory (LST) analysis. Four isothermal wall cases with Tw/T0= 0.5, 0.7, 0.8 and 0.9, as well as an adiabatic wall case are considered. Results of both DNS and LST indicate that wall temperature has significant effects on the growth of disturbance waves. Cooling the surface accelerates unstable Mack II mode waves and decelerates the first mode (Tollmien–Schlichting mode) waves. LST results show that growth rate of the most unstable Mack II mode waves for the cases of cold wall Tw/T0=0.5 and 0.7 are about 45% and 25% larger than that for the adiabatic wall, respectively. Numerical results show that surface cooling modifies the profiles of rdut/dyn and temperature in the boundary layers, and thus changes the stability haracteristic of the boundary layers, and then effects on the growth of unstable waves. The results of DNS indicate that the disturbances with the frequency range from about 119.4 to 179.1 kHz, including the most unstable Mack modes, produce strong mode competition in the downstream region from about 11 to 100 nose radii. And adiabatic wall enhances the amplitudes of disturbance according to the results of DNS, although the LST indicates that the growth rate of the disturbance of cold wall is larger. That because the growth of the disturbance does not only depend on the development of the second unstable mode

一种通用的口语报告编码方案

本文根据纽厄尔和塞蒙的信息加工理论，建立了一套通用的口语报告编码方案，并以一个简单的“做中学”实验为例，说明如何利用这一编码方案分析口语报告。这一通用的口语报告编码方案有以下两个优点：一方面，它为定量化地考察复杂认知活动的过程和机制提供了条件；另一方面，它使研究者对不同口语报告进行的分析具有可比性，也使口语报告分析的研究可以重复验证