Deficiency of the adrenomedullin-RAMP3 system suppresses metastasis through modification of cancer-associated fibroblasts （アドレノメデュリン(AM)-RAMP3系の欠損は、癌関連線維芽細胞の性質を変化させ、臓器間転移を抑制する）

信州大学(Shinshu university)博士（医学）雑誌に発表。ONCOGENE. 39(9):1914-1930 (2020); doi:10.1038/s41388-019-1112-z.Thesis戴　昆. Deficiency of the adrenomedullin-RAMP3 system suppresses metastasis through modification of cancer-associated fibroblasts （アドレノメデュリン(AM)-RAMP3系の欠損は、癌関連線維芽細胞の性質を変化させ、臓器間転移を抑制する）. 信州大学, 2020, 博士論文.doctoral thesi

Optoelectronic properties of single nanowire field effect transistor

本篇論文主要探討的是單根奈米線的元件製作，並對此元件進行在場效電晶體特性及光感應特性上之研究。本研究改變一般傳統場效電晶體結構的作法,以單根奈米線當作載子通道,將載子通道移至氧化層上方,並將矽基板當作背部閘極加以偏壓來對奈米線引起電場效應, 使得有效載子通道的導電載子濃度變化,進而改變通道電阻及載子漂移率。 有鑑於此，我們先以汽相-液相-固相成長機制及有機金屬化學氣相沉積方法長出三種不同材料的奈米線：二氧化鈦奈米線、氧化鋅奈米線、氧化鋅/硒化鋅-核/殼奈米線，再運用光學微影製程技術與電子束微影技術來成功連接單根奈米線兩端,形成單根奈米線場效電晶體。除此之外，我們以模擬太陽光垂直照射於場效電晶體的單根奈米線上，研究功率強度與不同照射時間後的電流效應影響。 在單根二氧化鈦奈米線元件部分，在閘極偏壓的控制下，確實可使有效載子濃度變大，導致輸出電流強度會增強，為n型半導體，且電流情形並非呈現原點對稱；其對光的開與關電流比例可以高達1000，而且光功率強度比起照射時間對二氧化鈦奈米線的影響更是顯著。在氧化鋅奈米線部分，我們也發現到，氧化鋅奈米線也是屬於n型載子通道；在對光感應方面，開/關的電流比值最高可達到300倍(光功率為100 毫瓦特、外加電壓為1伏特時)，具有良好的感光性質。此外，當我們在氧化鋅奈米線外層包覆成長硒化鋅後，與氧化鋅奈米線比較可明顯看出硒化鋅/氧化鋅奈米線的光感應的確比氧化鋅奈米線光感應的效果好，光電流強度可再大幅增加200倍。Fabrication of single nanowire devices and their optoelectronic properties and field effect transistor (FET) characteristics are reported in this thesis. Vapor-liquid-solid growth (VLS) and metal organic chemical vapor deposition (MOCVD) were used to grow three different nanowires: TiO2 nanowires, ,ZnO nanowires, and ZnO / ZnSe core / shell nanowires. Optical lithography and electron beam lithography technology were then used to fabricate single nanowire field effect transistors. For TiO2 single nanowire FET we found that the carrier concentration in the nanowire can be increased by gate bias, and from its FET characteristic we conclude that the TiO2 nanowire grown with ours method is a n-type semiconductor. We also found that the TiO2 single nanowire FET is very sensitive to the light exposure. The on-off ratio of the device current can reach 1000 when the incident light power is 30 mW. From the electric characteristic of ZnO nanowires FET, we found that ZnO nanowires are n-type semiconductors. The on / off current ratio of the ZnO nanowires FET can reach 300 at an incident optical power of 100 mW at an applied voltage of 1 V. After the ZnO wire was coated with ZnSe shell to form ZnO-ZnSe cor-shell nanowire, the light-sensitive of the device increase quite dramatically. We found the current intensity in the ZnO/ZnSe nanowire can increase by 200-fold as compared with the ZnO nanowires in the same light exposure condition. This dramatic increase of the light–induced current is attributed to the charge separation effect in of the type-II band alignment of the ZnO/ZnSe heterostructure

AN INTERVIEW WITH LIN RAN LIN RAN'S INTERVIEW of ARTISTS,CURATORS AND CRITICS ON THEIR OPINIONS ON ENVIRONMENTAL PROTECTION

林苒:鲍老师,您近年策划指导了多次关于环境方面的展览,请问您是出于什么样的心态去做这类的展览呢？这些展览分别是什么主题？它们的区别是什么？鲍昆:环境问题从19世纪末以来是世界现代性发展中诸多问题中的一个,而且随着二战之后资本主义生产的大发展,渐渐成了殖民战乱这样的灾难之后最为重要的问题。甚至,它和政治、经济的矛盾纷争深深地融为一体,有时甚至直接就是导火索。但是环境问题的发展不像战争那样具有普遍的突发暴烈特征,反而属于温水煮青蛙式的渐进式,只是其危害绝不逊于前者。从长

Development of a Fiber Optical Chemical CO2 Sensor

研究开发了一种基于指示剂的二氧化碳光纤化学传感器,采用具有高气体可透过性和低折射率的无定型聚四氟乙烯(Teflon AF)材料作为液芯波导管,高灵敏度微型CCD分光光度计作为检测器,溴百里酚蓝(BTB,bromothymol blue)和Na2CO3为指示剂缓冲溶液。在0～194 ppm的CO2浓度范围内,传感器最佳精度为±1.21ppm,响应时间(99％)约为2 min。传感器具有体积小,能耗低等特点,适于现场长期自动监测。 【英文摘要】 A reagent based CO2 fiber optical chemical sensor was developed. The sensor utilizes a Teflon AF tubing with high gas-permeability and low refractive index as a liquid core waveguide. A high sensitivity micro CCD spectrophotorneter was used as a detector, and BTB (bromothymol blue) dissolved in aqueous HCO3- /CO32- was applied as indicator-buffer solution. The sensor is able to achieve a precision of± 1.21 ppm in a xCO2 range of 0 - 194 ppm, and a response time (99 %) of 2 min.863计划(2002AA635140);; 教育部(200280421020);; 杰出青年科学基金(49825162)资助项

准噶尔盆地荒漠啮齿动物群落共存机制及其种多样性研究

该项研究提示出，短命植物的脉冲式增长和大量存在，导致生存资源丰富时期鼠种间无竞争而共存。随短命植物迅速枯萎和消失，雄鼠仍具生殖力的前提下，各鼠种的雌鼠均已停止了繁殖活动。经环境异质性测定、生境和食物选择、室内外种子托盘法和形态解剖等方法，研究准噶尔盆地沙质、黄土、砾质和荒漠鼠类群落的生态分离、共存机制及其塑造的种多样性。由此得出短命植物期鼠种间为无竞争共存，其后存在开阔/隐蔽小生境、土壤种子库利用浓度植被层片垂直利用、食植与食虫、取食种子大小等5种生态分离及其构成的共存机制。各鼠类群落的共存机制不同，其共性为荒漠异质性低，资源存在制约时期并沿异质性主维轴呈不同的存在方式，诸鼠种在进化生态上形成了各异的生物特征，以此成为某资源的最佳摄食者。基于该研究分析该盆地及相邻区的鼠种多样性以及该盆地成为其东－西部鼠种渗透与扩散过渡区的共存机制内因，获得较好的结果

子午沙鼠的微栖息地选择特征及其对采食行为研究

选择吐鲁番盆地沙质荒漠区,以子午沙鼠为模型研究典型荒漠鼠种的微栖息地选择和取食对策。结合网格样方法和人工食物盘法通过对目标种采食点与灌木(高度在1m以上)的距离(≤1m,≤2m和>2m),采食点地形地貌(土质-沙质,谷地-沙丘)的分析确定目标种的微栖息地选择;通过目标种对食物盘的取食强度(放弃密度GUD)确定目标种的微栖息地选择偏好。结果显示,目标种对距灌木≤2m点和≤1m点的选择差异不显著,对于≤1m和>2m的点选择差异显著;对于≤2m点和>2m点的选择差异显著。距灌木2m的空间可能是目标种取食活动的敏感范围。对于基底为土质或沙质的微栖息地,目标种选择差异显著,对于谷地和沙丘,目标种的选择没有显著差异。对GUD的分析显示,在距灌木2m范围内目标种的取食强度高于此范围之外,同时偏好在沙质地表采食,但在谷地和沙丘之间没有差异

离子速度成像方法研究cf3i分子光解反应动力学

建立一套离子速度成像系统，这套系统通过采用最新的“速度映像”技术克服了离子源空间分布对速度分辨率造成的模糊。利用这套系统得到了ＣＦ３Ｉ在２７７ｎｍ附近光解反应产物Ｉ＾＊（＾２Ｐ１／２）和Ｉ（＾２Ｐ３／２）的速度和角度的高分辨率分布，首次利用重构的Ｉ（＾２Ｐ３／２）碎片三维空间速率分布揭示了其两个不同的解离通道

A high precision, fast response, and low power consumption in situ optical fiber chemical pCO(2) sensor

A sensor system suitable for monitoring changes in partial pressure of carbon dioxide (pCO(2)) in surface seawater or in the atmosphere has been developed. Surface seawater samples are pumped into a PVC tube enclosing an inner Teflon AF tube, which served as a long pathlength gas-permeable liquid-core waveguide for spectrophotometry. The Teflon cell contains a pH-sensitive indicator-buffer solution consisting of bromothymol blue (BTB) and sodium carbonate. Carbon dioxide in the sample diffuses into the indicator-buffer solution to reach equilibrium, resulting in pH changes, which are detected by changes in the absorbance of BTB at wavelengths of 620 and 434 nm. The pCO(2) in the sample is then derived from the pH change. The sensor has a response time of 2 min at the 95% equilibrium value and a measurement precision of 0.26-0.37% in the range 200-800 mu atm pCO(2). This chemical sensor takes advantage of a combination of long pathlength, multiple wavelength detection, indicator solution renewal, and in situ automatic control technology, and has the feature of low power consumption (the average being similar to 4W with a peak of similar to 8 W). (C) 2008 Elsevier B.V. All rights reserved

新疆脊椎动物标本生物学资料信息系统

该系统包括新疆脊椎动物五大类的标本资料和生物学资料,建有5个标本库、5个资料库和4个代码库,已存入222种资料信息、251种标本数据及825条动物名录,形成了一个有一定规模的新疆脊椎动物标本、生物学资料的数据实体。系统按常规信息管理系统设计,采用模块化结构,运用多级菜单提供编辑、查询、计算、显示、打印和管理功能,能方便地进行数据的添加、变更、删除;可按中文名称、拉丁文名称和代码进行查询;可按栖息环境、区系分布、标本存放等进行统计并输出结果