Research on the Investment Preference and Change in A-share Market of China’s Insurance Capital

从2005年至2015年十年间，我国民众的保险需求以及社会资本对保险行业的投资热情得到了非常显著的提升，承保业务的蓬勃发展拉动了保险公司在投资业务方面的巨大需求。在目前保险公司投资渠道有限，国内债券市场缺乏长久期债券品种的环境下，保险资金对股票市场的投资正显示出越来越大的投资热情，其中，成立时间较短的中小保险公司为此贡献了重要力量。然而近年来保险公司举牌上市公司风波频现，以及万能险乱象引发了市场对保险公司“稳健经营稳健投资”的质疑。保险产品的保障属性变淡，产品高收益背后是不断加大的高投资风险，“保险姓保”问题开始受到监管层的关注。 然而，保险资金整体作为“机构投资者”中的一类，在实际股票投资...From 2005 to 2015, people’s demand of insurance and the passion of social capital in insurance have increased enormously. And the rapid development of underwriting business has also produce huge demand of investment of insurance company. Because of the lack of investment tools and long duration bonds, the insurance capital has shown great passion in stock market. And small and medium-sized insuran...学位：保险硕士院系专业：经济学院_保险硕士学号：1562014115211

超声心动图监测45例法布雷病患者心脏早期受累的特征分析

目的分析45例临床确诊的法布雷病（AFD）患者的临床特征，同时应用超声心动图二维斑点追踪技术（2D-STE）评估法布雷病患者应变图像，以期探索法布雷患者心脏早期受累在超声心动图（UCG）上的表现。方法本研究为观察性研究。共纳入确诊为AFD的患者45例，根据UCG测量左室壁有无肥厚，分为左室壁肥厚组（17例，室间隔或左室后壁厚度≥12 mm）和无左室壁肥厚组（28例）。收集患者基线资料，并对所有患者进行常规UCG检查及二维斑点追踪超声心动图分析。应用TomTec工作站分析超声心动图图像，比较两组的临床基线资料、UCG常规参数及心肌应变特征。结果本研究共纳入45例AFD患者，年龄（32.33±16.11）岁，其中男性27例（60.00%）。左室壁肥厚组17例（37.78%），无左室壁肥厚组28例（62.22%）。45例患者的左室射血分数（LVEF）均正常（＞50%）。与无左室壁肥厚组相比，左室壁肥厚组患者的靶器官受累比例明显增加。与无左室壁肥厚组相比，左室壁肥厚组患者的E/A，平均E/E'明显升高（P＜0.05）；左室壁肥厚组的整体、心肌层、心内膜以及各节段的纵向应变（LS），周向应变（CS）及径向应变（RS）的差异均无统计学意义（P 值均＞0.05）。AFD患者心肌层的整体和各节段LS、CS的绝对值均低于心内膜的对应值（P 值均＜0.05）。AFD患者的中间段的LS、RS绝对值较基底段和心尖段高（P 值均＜0.05）。结论早期收缩功能障碍与左室壁厚度无明显关系。2D-STE心肌应变可以早期监测AFD室壁肌层受累较心内膜严重，而中间段受累较心尖段和基底段轻

Loop-Mediated Isothermal Amplification(LAMP) for Detection of Alicyclobacillus acidoterrestris in Foods

目的:利用环介导等温扩增技术建立食品中酸土环脂芽孢杆菌快速检测方法。方法:针对酸土环脂芽孢杆菌16S序列设计特异引物,再优选反应体系,用显色法检测实验结果。结果:该方法能够在63℃条件下1 H内检出食品中酸土环脂芽孢杆菌,所设计的引物有良好的特异性;灵敏度达6.7 Cfu/M l(弱阳性)。结论:该方法具有高效、特异性强和敏感性高等特点,可满足酸土环脂芽孢杆菌快速检测筛选的要求。Purpose: A loop-mediated isothermal amplification(LAMP) method was established for the detection of Alicyclobacillus acidoterrestris in foods.Methods: After optimization of the reaction conditions of LAMP including the concentrations of primers, reaction time and amplification temperature, the LAMP method was developed, and its sensitivity and specificity were evaluated.Results: The method was capable of rapidly and specifically detecting A.acidoterrestris in foods within 1 hour at a constant temperature of 63 ℃.The sensitivity of the method was 6.7 CFU/m L and the specificity was 100%.Conclusions: The LAMP method is efficient, highly sensitive and specific, and suitable for the rapid detection of A.acidoterrestris in various food samples.福建省漳州市自然科学基金项目(ZZ2012J16

密码学混合式课程建设探索

针对密码学教学过程中存在缺少价值引领、教学手段僵化、实践教学缺失、语言表达不清、缺少自主可控等问题，论文分析了当今密码学课程建设现状，提出了多元融合的密码学混合式教学模式，实现了知识与价值观的混合、线上与线下的混合、理论与实践的混合、中英文教学方式的混合、国际视野与中国标准的混合，提高了学生的学习兴趣和学习效率。</jats:p

Effects of Morinda officinalis-containing serum on the m RNA expression of C-FOS and Cbfa1 in osteoblast and osteoclast co-cultured system

目的观察不同浓度巴戟天含药血清对体外培养成骨-破骨细胞共育体系中原癌基因(C-fOS)、核心结合因子(CbfA)1 MrnA表达的影响。方法提取24 H内新生Sd乳鼠颅盖骨分离培养成骨细胞,采用5周龄Sd大鼠双侧股骨、胫骨的骨髓基质细胞,加入集落细胞刺激因子(M-CSf)和细胞核因子κb受体活化因子配体(rAnkl)诱导培养破骨细胞。采用碱性磷酸酶(AlP)染色鉴定成骨细胞,抗酒石酸酸性磷酸酶(TrAP)染色、骨吸收陷窝甲苯胺蓝染色、电镜扫描等鉴定破骨细胞,体外建立成骨-破骨细胞共育体系,设置低、中、高三种浓度巴戟天含药血清组和不含药血清组,干预3 d后提取各组总rnA,应用逆转录-聚合酶链反应(rT-PCr)方法测定各组C-fOS、CbfA1 MrnA表达量。结果不同浓度巴戟天含药大鼠血清对成骨-破骨细胞共育体系C-fOS有抑制作用,对CbfA1 MrnA的表达有促进作用。高浓度含药血清组两者的表达差异显著(P<0.05,P<0.000 1)。结论巴戟天含药血清可抑制成骨-破骨细胞共育体系C-fOS的表达,促进CbfA1 MrnA的表达,从而达到降低破骨细胞分化成熟及骨吸收活性,促进骨形成。Objective To observe the effects of the serum of Morinda officinalis( RMO) on the expression of C-FOS and core binding factor Alpha1( Cbfa1) in osteoblast and osteoclast co-cultured system.Methods Osteoblasts were separated from the cranium of 24 hours newborn SD rat.Bone marrow cells were harvested from bilateral femora and tibiae of five weeks old SD rat,and M-CSF and RANKL were used to induce osteoclast formation.Osteoblast cells were confirmed by alkaline phosphatase( ALP) stain,osteoclast cells were confirmed by tartrate resistant acidphos phatase( TRAP) stain,Toluidine blue stain and bone resorption assay.Osteoblast and osteoclast co-cultured system was established in vitro.Low,middle,high concentrations of serum RMO and control groups were set.Total RNA was extracted after intervention 3 days,C-FOS and Cbfa1 mRNA expression were measured by real-time PCR.Results Different concentrations serum of RMO had inhibitory effect on the expression of C-FOS and enhance the mRNA expression of Cbfa1 mRNA,and the function on both indicated a statistically significant difference at high concentration( P<0.05,P<0.000 1).Conclusions The serum of RMO could down-regulate the expression of C-FOS and up-regulate Cbfa1 mRNA in osteoblast and osteoclast co-cultured system,consequently reduce osteoclast differentiation and activity of bone resorption,enhance bone formation.国家自然科学基金资助项目(No.81272168); 福建省医学创新课题资助项目(No.2012-CXB-32

金属快速成形3D 打印技术与应用

With the gradual application of advanced manufacturing technology, the development of forced, removed and stacked forming technology is very rapid. As a relatively new rapid addition forming technology, 3D printing technology has achieved very good results in many fields, greatly improving the efficiency of parts, and playing an important role in promoting the development of social economy. This paper focuses on the analysis of metal 3D printing technology and equipment, and shares the case of 3D printing in real life

分辨率对DOAS测量二硫化碳影响的研究

差分光学吸收光谱技术（DOAS）由于易操作,耗费低,且具有高准确性和高分辨率等优点,非常适合对大气中难闻的有毒气体二硫化碳（CS2）进行实时监测。在DOAS测量过程中,分辨率的选择直接决定了CS2测量准确度。文章主要研究了分辨率对CS2被检测到的特征吸收结构形状的影响,以及CS2差分吸收截面随分辨率的变化趋势,从而确定了分辨率对CS2的最低可检测浓度的影响。通过研究分辨率与光强的关系,确定了分辨率与信噪比（S/N）的函数关系式,得出了DOAS测量CS2的最佳信噪比范围为0.41～0.50nm（FWHM）。在此范围既能够实现对CS2的准确定性定量分析（五种标样线性相关性r=0.999 9,测量10次的相对标准偏差小于0.3%）,又能达到对CS2测量所需要的高灵敏度,高选择性和适用的时间分辨率同时保证了CS2具有区别于其他物质的特征吸收结构。最后对北京市丰台区的CS2进行了实时、连续地监测,取得了良好的效果