线粒体质量控制在外源化学物引起坏死性凋亡中的作用

坏死性凋亡是一种可调控的、半胱氨酸天冬氨酸蛋白酶(Cysteine aspartic acid specific protease,Caspase)非依赖的程序性细胞死亡,相较于细胞凋亡,其主要特点是没有核固缩和气球样变,而出现的是线粒体肿胀和三磷酸腺苷(Adenosine triphosphate,ATP)耗竭、胞质肿胀和空泡形成,其最终引起质膜破裂和通透性改变,释放损伤相关分子,如白细胞介素1α、高国家自然科学基金(81573181,81472997);;福建省自然科学基金(2015J01344

印度能源趋势概述:低碳增长与发展的挑战

文章对印度二氧化碳的排放情况、推动因素及未来展望做了概述,并提出了如下结论:(1)为了减少贫困和提高生活水平,印度有关能源的排放量仍需增加,但增加多少还不确定;(2)尽管依赖煤炭,但由于较低的能源强度和无碳电力的显著增长,印度仍会走低碳经济的发展道路;(3)在不久的将来,能源和碳强度的下降趋势将继续保持,但这种趋势可能会被不可持续的发展模式所减弱

Determination of the number of ψ(3686) events taken at BESIII

The number of ψ(3686) events collected by the BESIII detector during the 2021 run period is determined to be (2259.3±11.1)×106 by counting inclusive ψ(3686) hadronic events. The uncertainty is systematic and the statistical uncertainty is negligible. Meanwhile, the numbers of ψ(3686) events collected during the 2009 and 2012 run periods are updated to be (107.7±0.6)×106 and (345.4±2.6)×106, respectively. Both numbers are consistent with the previous measurements within one standard deviation. The total number of ψ(3686) events in the three data samples is (2712.4±14.3)×10^