多种手势对应同一语义的柔性映射交互算法的研究

针对智能交互界面中手势识别错误导致交互界面变化错误和手势不识别两个基本问题,本文设计并实现了基于手势交互的智能教学界面,该系统可以通过获取教师的手势信息与教师进行交互.主要创新点在于提出了多种手势对应同一语义的柔性映射交互算法.本文选取了14种自然交互手势,分析了对应同一语义的多种手势之间的共同特征.实验结果显示,该算法能够有效降低用户负荷.该算法已经用于一个基于手势交互的智能教学系统界面中.国家重点研发计划(No.2018YFB1004901)国家自然科学基金(No.61472163,No.61603151)山东省重点研发计划(No.2017GGX10146

Effects of morphine withdrawal on place learning and response learning in rats

目的 观察在经历特定剂量吗啡前期用药后的停药状态下,大鼠空间学习和反应学习过程的改变.方法 在前期用药阶段,戒断组及持续给药组皮下注射吗啡5 mg&middot;kg-1&middot;d-1,连续6 d,盐水组在相同时间注射生理盐水,之后,各组进行水迷宫空间学习任务或反应学习任务.在训练期间,戒断组和盐水组每天注射盐水,持续给药组连续给药.结果 空间学习任务中,在训练第3轮,各组正确率分别为戒断组[(97.0&plusmn;6.0)%]、持续给药组[(79.9&plusmn;20.1)%]、盐水组[(61.0&plusmn;20.6)%],戒断组显著高于盐水组( P &lt;0.01 post-hoc LSD test),重复测试显示,戒断组空间学习显著优于盐水组( P &lt;0.05),在空间反向任务中,戒断组表现亦显著优于盐水组.反应学习任务及反应反向学习任务中,各组间差异无显著性.结论 本研究提示在吗啡戒断状态下大鼠空间学习过程增强.<br /

Overexpression of VTE1 from Arabidopsis Resulting in High Vitamin E Accumulationand Salt Stress Tolerance Increase in Tobacco Plant~ *

维生素E在动物细胞内具有抗氧化等重要作用,但在植物体内的功能却鲜为人知.本实验利用CaMV35S启动子与来源于拟南芥的编码生育酚环化酶(TC)的cDNA(VTE1)构建的嵌合表达载体,以根癌农杆菌介导的叶盘法转化烟草W38.实验结果表明,具有卡那霉素抗性的再生植株经RT-PCR检测,得到了与阳性对照一致的495bp的目标片段;转基因植株的VE含量比对照植株高2倍左右,个别株系高达11倍.实验还发现,在耐盐性实验中转基因植株对盐的抗性明显高于野生型烟草;同时,在不同盐浓度(150、250mmol/L)胁迫下转基因植株VE含量比未转化植株增加了1.3~1.8倍,首次证明VTE1与植物耐盐性之间的关系.图7参30Vitamin E is an essential antioxidant in the human cells, while its function in plants is unknown. In this study, tobacco W38 was transformed with a construct containing a cDNA insert encoding tocopherol cyclase (VTE1) from Arabidopsis under the control of the cauliflower mosaic virus (CaMV) 35S promoter. The transgenic tobacco plants were confirmed by RT-PCR, which yielded the same PCR product of 495 bp as the positive control. Compared to the wild type controls, up to 11 times of vitamin E were accumulated in different transgenic lines. Interestingly, the over-expression of VTE1 dramatically increased the salt stress tolerance in tobacco plants. To our knowledge, it is first reported that VTE1 can increase salt stress tolerance in plants. Fig 7, Ref 30国家自然科学基金重点项目~

Establishment of a method to quantitatively detect FLT3 internal tandem duplication in acute myeloid leukemia with denaturing high-performance liquid chromatography

目的:建立一种应用变性高效液相色谱技术(dHPlC)相对定量检测急性髓细胞白血病(AMl)患者fMS样酪氨酸激酶3(flT3)基因的内部串联重复(ITd)突变的方法。方法:根据flT3-ITd突变基因多位于14外显子而设计引物,用聚合酶链反应(PCr)方法特异性扩增121例AMl患者flT3-ITd突变基因,再用dH-PlC技术相对定量检测flT3-ITd等位基因突变的情况;与毛细管电泳法(CE)检测突变的结果对比进行该方法的有效性检验;最后与121例样品PCr扩增产物的测序结果进行对比。结果:经dHPlC分析后均能得到特征性的洗脱峰。121例样本中检测到flT3-ITd突变阳性的样本13例,总阳性率为10.7%,阳性突变等位基因的比例不一,分布范围中位数为34.5%(11.4%-80.2%),为21-87 bP单个插入片段。阳性率和突变比例与CE方法检测结果相比较均无显著差异(P>0.05),并与121例样本flT3-ITd扩增PCr产物基因测序结果一致。结论:成功建立了一种应用dHPlC相对定量检测AMl患者flT3-ITd基因突变的方法。AIM: To establish a relatively-quantitative method to detect the internal tandem duplication(ITD) mutation of Fms-like tyrosine kinase 3(FLT3)gene in acute myeloid leukemia(AML) patients using denaturing high-performance liquid chromatography(DHPLC).METHODS: According to the fact that much more FLT3-ITD mutations are located in exon 14,we designed the primers,and use the method of polymerase chain reaction(PCR) to specifically amplify FLT3-ITD mutation gene in 121 cases of AML,and relatively quantified the situation of mutant allelic gene of FLT3-ITD by the method of DHPLC.The effectiveness of DHPLC was verified by the method of capillary electrophoresis(CE).The sequenced results from PCR amplified products of 121 samples were compared.RESULTS: A characteristic of elution peak was detected by DHPLC with 10.7% overall positive rate(13/121) and varied in the proportion of mutant alleles,with a single duplicated insert fragment from 21 bp to 87 bp.The median range of mutant alleles was 34.5%(11.4%-80.2%).No significant difference of the positive rates and mutation proportions between the results with DHPLC and the results with CE method was observed.The results of FLT3-ITD mutant gene of 121 samples were consistent with the results using sequencing method.CONCLUSION: A relatively-quantitative method to analyze AML patients with FLT3-ITD mutation by DHPLC is successfully established

Study on removal boron from solargrade silicon with hydrometallurgy

湿法提纯作为冶金法制备太阳能级硅的前处理工序,可以去除大部分金属和硼杂质。研究了以氢氟酸-硫酸混合酸为浸出剂,有机溶剂甲醇作为后处理剂,去除硅粉中硼杂质的方法。采用电感耦合等离子体发射光谱仪(ICP)等对产品进行表征。酸浸过程优化工艺条件:硫酸质量分数为55%,氢氟酸质量分数为7%,酸浸温度为70℃、酸浸时间为4 H、液固质量比为8∶1。酸浸后可使硅粉中的硼杂质质量分数由6.893x10-6降至3.867x10-6,去除率为41.9%。在酸浸基础上采用有机溶剂甲醇作为后处理剂,杂质硼质量分数降至3.84x10-6,去除率为44.29%。从硼酸浸后形成的产物入手探索提高硼去除率的方法,实验验证了该方法的可行性,为研究湿法冶金预处理太阳能级硅提供了新的参考。As a pretreatment unit for preparing solargrade silicon(SG-Si) by metallurgic method,wet purification could remove most metallic impurities and nonmetallic impurities,such as boron.Experiment researched a new method to remove boron from SG-Si with mixed hydrofluoric acid-sulfuric acid as leaching agent and with organic solvent methanol as posttreatment agent.Samples were characterized by ICP and other analysis methods.When SG-Si powder had been leached at optimized conditions as follows:mass fraction of sulfuric acid was 55%,mass fraction of hydrofluoric acid was 7%,reaction temperature was 70 ℃,reaction time was 4 h,and liquid-solid mass ratio 8∶1,it was found that mass fraction of impurity boron in SG-Si was reduced to 3.867×10-6 from 6.893×10-6 and the removal rate was 41.9% after acid leaching;on the basis of the former procedure,mass fraction of impurity boron was reduced to 3.84×10-6 and the removal rate was 44.29% when treated with organic solvent.Experiment proved the feasibility of the method and provided a new reference for researching on the pretreatment of SG-Si by hydrometallurgy

Analysis on epidemiological charateristics of chlamydia trachomatis infection in Jiangsu Province,2006-2011

目的了解江苏省2006-2011年生殖道沙眼衣原体感染的流行病学特征,为制定防治生殖道沙眼衣原体感染的策略提供科学依据。方法收集2006-2011年江苏省通过中国疾病预防控制信息系统报告的生殖道沙眼衣原体感染病例资料,并对资料进行流行病学分析。结果 2006-2011年,江苏省生殖道沙眼衣原体感染发病率呈快速上升的趋势,2006年为0.12/10万,2011年为3.15/10万,发病率年均增长速度为92.23%;在报告的5 859例病例中,男女性别比为0.3∶1,各年生殖道沙眼衣原体感染男女性别差异有统计学意义;发病年龄主要集中在20~29岁年龄组,占50.96%;江苏省生殖道沙眼衣原体感染报告病例主要集中在苏南和苏中的较发达城市;主要以家庭及待业者和工人为主。结论江苏省生殖道沙眼衣原体感染发病率快速增长,应加强对生殖道沙眼衣原体的防治,以控制其感染的快速流行。江苏省医学重点人才(RC2011086);江苏省医学重点人才(RC2011087); 江苏省科技项目(Y201029

Study on plant photosynthate allocation dynamic and simulation of grassland and maize agricultural ecosystems

植物光合产物分配直接影响到陆地生态系统的生产力。准确模拟植物光合产物分配动态及其对环境变化的响应将直接影响陆地生态系统生产力和碳收支的准确评估。本论文首先探讨了土柱法和不同直径的土钻法及其不同取样方案对草原根系生物量测定结果准确性的影响；进而基于羊草种群的温室模拟试验数据、2004~2008 年玉米农田生态系统野外观测试验数据和文献数据，研究了种群密度和环境因子对植物光合产物分配格局的影响，发展了草原与玉米农田生态系统的植物光合产物分配模型。主要结论如下： (1) 小钻法(3.8cm)较土柱法和大钻法(10cm)显著地低估了草原植物的根系生物量。与土柱法(1m´1m)相比，小钻法对0~30cm 土层根系生物量的低估比例达52%，这主要是由洗根和取样过程中的根系损失造成的。 (2) 草原植物根系生物量取样误差(Coefficient of variation, CV)随取样数目的增加呈对数关系减小(CV=14.37-3.42 ln(Sample size-0.0011), R2=0.75, n=26, P＜0.001)。需要5 个0.5m×0.5m土柱、15 个直径为10cm的土钻或65 个直径为3.8cm的土钻，方可获取95%置信区间下10%相对误差的草原植物根系生物量。在内蒙古典型草原，小钻法不是根系生物量适宜的取样方法，系统取样较随机取样并没有降低根系生物量的取样误差，建议分层随机取样更适合该类型根系生物量的获取。 (3) 本研究中密度竞争对羊草种群的光合产物分配格局没有直接的影响，但其造成微环境的差异会导致羊草种群的光合产物分配格局发生改变，羊草种群光合产物向根系的分配比例随生长进程逐渐增加。 (4) 发展了基于光照、水分和养分影响的普适性植物光合产物分配模型，并在个体、站点和区域水平进行了验证。结果表明，所建光合产物分配模型较Friedlingstein 光合产物分配模型能更好地模拟不同植被类型和不同空间尺度的植物光合产物分配动态

吗啡对大鼠选择性饮水动机的强化效应

目的：研究吗啡对大鼠选择性饮水行为和动机的影响。方法：给大鼠间歇性或连续性地饮用含吗啡的黄连素溶液，以大鼠在呈现两种不同溶液时选择吗啡溶液的比率为指标。进行测试，每3d一次，20d后，用高浓度吗啡蔗糖溶液进行干预后再测试。结果：大鼠饮用吗啡溶液2周后，吗啡溶液选择比率显著升高，并与饮用吗啡浓度和饮用程序有关。测试前饮用吗啡能降低吗啡溶液选择比率，亦存在显著剂量相关，结论：吗啡可以显著性增加大鼠选择性饮水行为，并与给药程序有关

REINFORCEMENT OF MORPHINE ON SELECTIVE DRINKING MOTIVATION IN RATS

目的: 研究吗啡对大鼠选择性饮水行为和动机的影响。方法: 给大鼠间歇性或连续性地饮用含吗啡的黄连素溶液 ,以大鼠在呈现两种不同溶液时选择吗啡溶液的比率为指标 ,进行测试 ,每3d一次。20d后 ,用高浓度吗啡蔗糖溶液进行干预后再测试。结果: 大鼠饮用吗啡溶液2周后 ,吗啡溶液选择比率显著升高 ,并与饮用吗啡浓度和饮用程序有关 ; 测试前饮用吗啡能降低吗啡溶液选择比率 ,亦存在显著剂量相关。结论: 吗啡可以显著性增加大鼠选择性饮水行为 ,并与给药程序有关