A STUDY ON THE STRUCTURE AND SPATIAL PATTERNS of CYCLOBALANOPSIS GLAUCA POPULATIONS IN WESTERN HUANGSHAN

黄山西坡青冈种群结构与分布格局研究陈小勇，张庆费，吴化前，宋永昌（华东师范大学环境科学系，上海，200062）ASTudyOnTHESTruCTurEAndSPATIAlPATTErnSOfCyClObAlAnOPSISglAuCAPOPulATIO...国家自然科学基

基于微流控技术的循环肿瘤细胞分析研究进展

癌症的精准诊疗是提高癌症患者生存率和生存质量的重要手段.液体活检通过采用非侵入采样方式,获取肿瘤病人全面、准确、实时的基因组、转录组及蛋白组等生物学信息,是一种新兴的癌症诊断技术,对癌症精确诊断、个体化治疗、预后评估等方面具有重要意义.循环肿瘤细胞(CTC)是一种从实体瘤组织脱落进入外周血的肿瘤细胞,因能提供完整的细胞生物学信息,是最具应用前景的液体活检靶标.然而, CTC的数量极其稀少、异质性强、所处外周血环境复杂等特点,给CTC的富集和分析带来了巨大的技术挑战.本文将总结本课题组近年来发展的基于CTC液体活检策略,着重讨论在CTC识别、富集与单细胞分析等方面的研究进展

中国旅游发展笔谈——品质旅游

我国经济已由高速增长阶段转向高质量发展阶段。就旅游业而言,也进入了品质化发展的关键阶段。随着人们出游机会的增多,人们对旅游的追求开始从\"有没有\"转向\"好不好\"。国务院发布的《\"十三五\"旅游业发展规划》关于旅游业发展形势的一个重要判断就是\"需求品质化\"。可以说,发展品质旅游既是对高质量发展国家战略的响应,也是满足人民群众美好生活需要的客观要求,同时是旅游业发展进入大众旅游中高级阶段之后的必然选择

类泛素蛋白及其中文命名

泛素家族包括泛素及类泛素蛋白,约20种成员蛋白.近年来,泛素家族领域取得了迅猛发展,并已与生物学及医学研究的各个领域相互交叉.泛素家族介导的蛋白质降解和细胞自噬机制的发现分别于2004和2016年获得诺贝尔奖.但是,类泛素蛋白并没有统一规范的中文译名. 2018年4月9日在苏州召开的《泛素家族介导的蛋白质降解和细胞自噬》专著的编委会上,部分作者讨论了类泛素蛋白的中文命名问题,并在随后的\"泛素家族、自噬与疾病\"(Ubiquitinfamily,autophagy anddiseases)苏州会议上提出了类泛素蛋白中文翻译草案,此草案在参加该会议的国内学者及海外华人学者间取得了高度共识.冷泉港亚洲\"泛素家族、自噬与疾病\"苏州会议是由美国冷泉港实验室主办、两年一度、面向全球的英文会议.该会议在海内外华人学者中具有广泛影响,因此,参会华人学者的意见具有一定的代表性.本文介绍了10个类别的类泛素蛋白的中文命名,系统总结了它们的结构特点,并比较了参与各种类泛素化修饰的酶和它们的生物学功能.文章由45名从事该领域研究的专家合作撰写,其中包括中国工程院院士1名,相关学者4名,长江学者3名,国家杰出青年科学基金获得者18名和美国知名高校华人教授4名.他们绝大多数是参加编写即将由科学出版社出版的专著《泛素家族介导的蛋白质降解和细胞自噬》的专家

The Energy Shift Study of The Characteristic X-ray Emitted by the Metal Crystal under the Impact of Heavy Ions

本论文的实验工作，是在兰州重离子加速器国家实验室完成的。实验中，使用ORTEC公司生产HPGe探测器测量了84MeV的12C4+重离子轰击系列金属箔生成的特征X射线。本论文研究了金属薄靶Ag、Cd、In和Sn产生的特征KX射线的能移现象。实验发现Ag、Cd、In和Sn的Kα1和Kα2X射线没有明显的能移现象，而Kβ1X、Kβ2X射线的能移却有100～200eV。对此，应用经典电磁理论详细地解释了该问题。在多组态Dirac-Fock（MCDF）程序计算的单空穴能移的基础上，分别根据实验中测量的特征KX射线的能移值和“几何”模型研究了重离子轰击下Ag、Cd、In和Sn的L、M壳层的多重电离。另外，在相同的条件下，实验测量的厚靶Au的特征LX射线能移不明显，而薄靶Au的特征LX射线却有1.5keV以上的能移。本文定性解释了该实验现象本论文的实验工作，是在兰州重离子加速器国家实验室完成的。实验中，使用ORTEC公司生产HPGe探测器测量了84MeV的12C4+重离子轰击系列金属箔生成的特征X射线。本论文研究了金属薄靶Ag、Cd、In和Sn产生的特征KX射线的能移现象。实验发现Ag、Cd、In和Sn的Kα1和Kα2X射线没有明显的能移现象，而Kβ1X、Kβ2X射线的能移却有100～200eV。对此，应用经典电磁理论详细地解释了该问题。在多组态Dirac-Fock（MCDF）程序计算的单空穴能移的基础上，分别根据实验中测量的特征KX射线的能移值和“几何”模型研究了重离子轰击下Ag、Cd、In和Sn的L、M壳层的多重电离。另外，在相同的条件下，实验测量的厚靶Au的特征LX射线能移不明显，而薄靶Au的特征LX射线却有1.5keV以上的能移。本文定性解释了该实验现

Isotope Effect On The heat Conductivity of Graphene

文章采用分子动力学模拟方法研究了同位素--(13)C掺杂的扶手型石墨烯纳米带的热传导行为。杂质散射导致的声子局域化显著地减小了系统的热传导系数。我们进一步研究了杂质散射对四种不同声子输运模式的影响,发现在相同的杂质浓度下,TA声子遭受的散射最强,而lA声子遭受的散射最弱。In this paper,we study heat conduction behaviors in armchair—Graphene Nanoribbons (AGNRs) with isotope --(13)C via molecular dynamics simulation.The phonon localization induced by impurity scattering strikingly decrease the heat conductivity of AGNRs.Special attentions are paid to the various effect of impurity on three types of acoustic phonons and the second sound.We find that on the same impurity concentration level transverse acoustic modes encounter the strongest scattering,while longitudinal acoustic modes encounter the weakest scattering

Studies of K-shell x-ray energy shifts induced by MeV/u heavy ions

This paper reports that the K x-ray spectra of the thin target 47Ag, 48Cd, 49In and 50Sn were measured by an HPGe semi-conductor detector in collisions with 84.5 MeV 6C4+ ions. Our experiment revealed the Kα x-ray energy shifts were not obvious and the Kβ1 x-ray energy shifts were about 90∼110 eV. The simple model of Burch et al has been previously used to calculate the K x-ray energy shifts due to an additional vacancy in 2p orbit. The present work extends the model of Burch to calculate the x-ray energy shifts of multiple ionized atoms induced by heavy ions with kinetic energy of MeV/u. In addition to our experimental results, many other experimental results are compared with the calculated values by using the model

Shape changes of Bohai Sea since the early 1940s

20世纪中期以来中国沿海经历了多次围填海热潮,2000年以来环渤海区域大规模围填海已使其成为近期中国围填海的重点区域。利用地形图、海图和遥感影像等资料获取的渤海多时相的平面重心、立体重心、海岸线、低潮线、等深线、海区面积和海区体积等指标变化信息,系统揭示渤海形态的长期变化特征。结果表明：近70年来,渤海面积不断萎缩,岸线普遍向海扩张,导致渤海的平面重心总体向东偏北方向移动,但渤海的平面周长总体呈增加趋势,平面形状趋于复杂;近50年来,渤海体积总体呈下降趋势,立体重心的位置趋于变深。自然条件下的河口三角洲发育和人类围填海活动是渤海形态变化的主要原因,但渤海形态变化的驱动力已由早期的以自然因素为主转变为近期的以人类活动因素为主

Spatial–temporal characters of coastline changes in the Strait of Malacca during 1988–2015

Based on Landsat remote sensing images, the coastlines on both sides of the Straits of Malacca were extracted in 1988, 2000, and 2015. From the aspects of coastline structure, coastline change rate, land-sea patterns, and strength of shoreline development and utilization, the spatial–temporal characteristics of the coastline changes during different time periods, 1988–2000, 2000–2015, and 1988–2015, on both sides of the Straits of Malacca and 12 major ports, such as the Penang Port, were analyzed. The conclusions are as follows: The coastline structure in the study area changed significantly, partiularly in the port area, where it gradually changed from single-type to multi-structure, and the length and proportion of the artificial shoreline increased sharply. Except for a few ports, the coastlines on both sides expanded seaward, and the average rates of the coastlines change on the north and south sides were 0.91 m/a and 1.20 m/a, respectively. The stability of the south shoreline of the strait was worse than that of the north bank because of the wide swamp of the south shoreline, low terrain, and rising sea level. The degree of the shoreline development and utilization continued to increase. The spatial difference between the north bank of the strait and south bank was significant. The growth of the first phase of the north bank was faster than that of the second phase, while the growth of the first phase of the south bank was slower than that of the second phase. The main driving factor of the changes in the coastline of the two sides was the transportation function of the Straits of Malacca