71 research outputs found

    A Case of Primary Central Nervous System Lymphoma that Developed during the Treatment of Castration-Resistant Prostate Cancer

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    A 64-year-old man was diagnosed with metastatic prostate cancer (cT3bN0M1b) and treated with combined androgen blockade. After two years and three months, he developed castration-resistant prostate cancer. Multiple lung metastases appeared after the administration of five courses of docetaxel and four courses of cabazitaxel therapy. Pulmonary metastases disappeared following rechallenge with docetaxel. Enzalutamide administration was initiated because docetaxel had to be discontinued due to adverse events. Although enzalutamide lowered the prostate specific antigen value, the patient staggered while walking and developed homonymous hemianopsia. Magnetic resonance imaging revealed a brain tumor. Although the brain tumor was considered to have metastasized from the prostate cancer, it was diagnosed as a primary central nervous system lymphoma using open-ended tumor biopsy. The brain tumor was eliminated with whole-brain irradiation. Thereafter, he has been treated with enzalutamide for 3 years without clinical progression of either disease

    甲状腺機能亢進症の発症にインターフェロン療法の関与が示唆されたC型慢性活動性肝炎の1例

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    金沢大学医学部附属病院内科(旧第一内科)We report a case of chronic active hepatitis type C associated with hyperthyroidism following a long-term interferon therapy. A 49-year-old man, who had received 1,440 ml of blood transfusion for massive bleeding from the gastric ulcer, was diagnosed as posttransfusion hepatitis 40 days later. While antibodies to thyroid microsomal antigen was positive, he was euthyroid state at the onset of hepatitis. A total of 474 MU of recombinant IFNホア was injected subcutaneously for 12 months. Nine months after the end of the therapy, finger tremor and body weight loss appeared. Laboratory data revealed overt hyperthyroidism. Thyroid stimulating antibodies, TSH receptor antibodies and antinuclear antibodies appeared following interferon therapy, as well as antibodies to thyroid microsomal antigen and islet cell surface antigen, which had been positive since the beginning of the therapy. Recently, various autoimmune responses have been shown to appear in the course of long-term interferon therapy, which will be of great clinical significance in the management of chronic type B and C hepatitis

    植物園利用報告 No.19 (1996)

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    1.原始的被子植物の分子系統学的解析 2.クスノキ科植物の分子系統学的研究 3.ハクサンコザクラの個体群動態の解析 4.シュロソウ属3種の繁殖特性の比較研究 5.クロユリ(Fritillaria camtschatcensis (L.) Ker-Gawl.)の個体群動態の解析 6.クロユリ(Fritillaria camtschatcensis (L.) Ker-Gawl.)の繁殖生態に関する研究 7.ヤマトアザミテントウ(Epilachna nipponica) とアザミ属(Cirsium)食草の地理的変異 8.角間の昆虫相 9.石川県におけるイチモンジセセリ幼虫とサナギの死亡要因:その寄生者相と寄生率 10.大気汚染物質の植物への影響実験 11.金沢大学角間キャンパスにおける冬季降水状況の観察とその特性:pH,導電率の測定 12.アキノキリンソウ(広義)の変異に関する研究 13.石川県内の小学校地における植物状況調査 14.ギシギシ属植物の発芽実

    D-アミノ酸を新たな生物系素材とする新規機能性食品開発拠点の形成

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    目次研究成果の概要1. Shiro Kato, Kenji Inagaki, Tadao Oikawa "Application of L-methionine γ-lyase in chiral amino acid analysis" Analytical Biochemistry vol.580, 56 - 61 (2019). 2. 加藤 志郎,老川 典夫 "哺乳動物におけるD-アミノ酸代謝" 微量栄養素研究 vol.36, 95 - 101 (2019). 3. 清水 栄人,中川 航希,平田 夏希,老川 典夫,細見 亮太,福永 健治,吉田 宗弘 "D-アラニンの給餌がマウスおよびラットの血清生化学検査値および遊離アミノ酸濃度に及ぼす影響" 微量栄養素研究 vol.36, 15 - 20 (2019). 4. 松村 吉信 "バイオフィルムの構造と特徴 : バイオフィルム制御にむけて" 食品と開発 vol.54, 93 - 96 (2019). 5. 岡島 浩平,老川 典夫 "乳酸菌によるセレンの蓄積と代謝" 微量栄養素研究 vol.35, 87 - 91 (2018). 1の論文は、著作権の関係により2021年5月31日まで非公開としております

    大型ヘリカル装置のIC聾アンテナと加熱特性

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    Ion-cyclotron heating was applied to the Large Helical Device by using single, trap loop antennas located at the outward side of the toroid. Good experimental results were obtaine with adequate plasma confining configurations and antenna conditionings.Loading resistance of the antenna was2-8Ohm and this was a sufficiently large value. Various heating characteristics were investigated by changing the heating modes, ion species and magneticfield configurations.The minoriy-ion heating mode resulted in the best heating performances,and the heatin gcharacteristics largely depended on the cyclotron resonance positions.There were some unique features due to the heliotron configuration.These results showed the effectiveness of the ICRF heating in a helical device and the appropriateness of the ICRF antenna design in the LHD

    2017~2019年度 関西大学研究拠点形成支援経費研究成果報告書

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    目次・研究成果の概要・2-1 工藤 宏人・宮前 翼・上田 正人・村山 憲弘・林 順一 "ノーリア骨格をテンプレートとした空孔内に水酸基を有する架橋化合物の合成とそれらの金属イオン包接性能" ネットワークポリマー論文集 vol.41, No.2, 65 - 71 (2020).・2-2 Mitsuaki Matsuoka, Kaho Yokoyama, Kohei Okura, Norihiro Murayama, Masato Ueda, Makio Naito " Synthesis of Geopolymers from Mechanically Activated Coal Fly Ash and Improvement of Their Mechanical Properties" Minerals 9, 791- 801 (2019).・2-3 Daisuke Shimoyama, Ryo Sekiya, Hiroto Kudo, Takeharu Haino, "Feet-to-Feet Connected Trisresorcinarenes" Organic Letters 22, 352 - 356 (2019).・2-4 Masato Ueda, Masahiko Ikeda, Shigeo Mori, Kenji Doi, Hisashi Kitagaki, Shuntaro Terauchi "Mechanical Properties of Additively Manufactured Porous Titanium with Sub-Millimetre Structural Units" Materials Transactions Vol.60, No.9, 1792 - 1798 (2019).・2-5 五十井 浩平・白杉 文香・松岡 光昭・林 順一・村山 憲弘 "種々のMg-Fe系複合酸化物を用いた希薄水溶液中のホウ素およびヒ素の除去" 環境資源工学 66, 29 - 35 (2019).・2-6 Toru Maruyama, Mitsuyoshi Tamaki, Keisuke Nakamura, Gou Nakamura "EFFECT OF MOLTEN METAL TEMPERATURE ON MOLD FILLING IN EVAPORATIVE PATTERN CASTING" International Journal of Metalcasting 13, 611–617 (2019).・2-7 Ryuta Saito, Toru Maruyama, Toshiki Nakamura, Hitoshi Yanagitani, Takahiro Sakai, Kouji Nakamoto "Influence of Tellurium Addition to Spheroidal Graphite Cast Iron on the Number of Graphite Particles" International Journal of Metalcasting Vol.13, 3, 571-577 (2018).・2-8 Masato Ueda, Rika Yamaguchi, Chika Fujita, Masahiko Ikeda "Control of Cell Adhesion on Titanium Dioxide by Light Irradiation" Materials Science Forum Vol.941, 2507 - 2512 (2018).・2-9 Hiroto Kudo, Mari Fukunaga, Kohei Shiotsuki, Hiroya Takeda, Hiroki Yamamoto, Takahiro Kozawa, Takeo Watanabe "Synthesis of hyperbranched polyacetals containing C-(4-t-butylbenz)calix[4]resorcinarene: Resist properties for extreme ultraviolet (EUV) lithography" Reactive and Functional Polymers 131, 361 - 367 (2018).・2-10 大隈 修・前 一廣・林 順一 "直接液化による豪州ビクトリア褐炭の高度利用 : 改新BCLプロセスによる化学原料の生産" Journal of the Japan Institute of Energy 98, 17 - 26 (2019).・2-11 Issei Suzuki, Ayako Kakinuma, Masato Ueda, Takahisa Omata "Flux growth of β-NaGaO₂ single crystals" Journal of Crystal Growth 504, 26 -30 (2018).・2-12 上田 正人、坂本 貴則、池田 勝彦 "電気抵抗率の精密測定による純チタンの組織評価" 環境資源工学 65, 74 -76 (2018).・2-13 Satoshi Imasaka, Hiroyasu Ishii, Jun\u27ichi Hayashi, Sadao Araki, Hideki Yamamoto "Synthesis of CHA-type titanosilicate zeolites using titanium oxide as Ti source and evaluation of their physicochemical properties" Microporous and Mesoporous Materials 273, 243-248 (2019).・2-14 Hiroto Kudo, Shizuya Ohori, Hiroya Takeda, Hiroki Ogawa, Takeo Watanbe, Hiroki Yamamoto, Takahiro Kozawa "Synthesis and Property of Tannic Acid Derivatives and Their Application for Extreme Ultraviolet Laser Lithography System" Journal of Photopolymer Science and Technology Vol.31, 221 - 225 (2018).・2-15 Hiroto Kudo, Tsubasa Miyamae, Kouta Kitagawa, Kohei Isoi, Norihiro Murayama, Jun\u27ichi Hayashi " Synthesis and Metal-Complexation Ability of Cross-Linking Materials Containing Noria-Templated Cavities with Pendant Carboxylic Acid Groups" Chemistry Select 3, 2223 - 2228 (2018).・2-16 上田 正人、池田 勝彦、土井 研児、 森 重雄、北垣 壽、寺内 俊太郎、関 あずさ "骨部分置換用ポーラスチタン : ポリグリコール酸 : 炭酸カルシウム複合体の開発" 高分子論文集 Vol.75, No.1, 69 - 74 (2018).・2-17 Alexandru C Sonoc, Jacob Jeswiet, Norihiro Murayama, Junji Shibata "A study of the application of Donnan dialysis to the recycling of lithium ion batteries" Hydrometallurgy 175, 133 - 143 (2018).2-3は、著作権の関係により非公開としております。2-8は、著作権の関係により非公開としております。2-9は、著作権の関係により非公開としております。2-10は、著作権の関係により非公開としております。2-11は、著作権の関係により非公開としております。2-16は、著作権の関係により非公開としております

    富里市・酒々井町内野牧新込境野馬土手・内野牧捕込跡

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    今回の調査区は、内野牧新込境野馬土手及び内野牧捕込跡が推定されていた地点である。調査区の北側では高さ3mを超える遺存状態の良好な野馬土手とそれに伴う溝2条を検出し、野馬土手の土層断面の観察から野馬土手の改修が6回行われていたことを確認した。溝は野馬土手の裾に沿って検出され、当初の野馬土手の構築に伴って掘削されたことが明らかである。また、野馬土手南側では平坦に整地したしまりの強い土が広範囲に何層にも堆積しており、調査区が捕込跡の一部であったことが判明した
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