敬西房信瑞の研究

大正大学2018年

Extraction of Xylindein from Chlorociboria aeruginosa complex and its biological characteristics

Xylindein (XL) was effectively extracted from wood rotted by Chlorociboria aeruginosa complex using a hot-compressed-water; in particular, with aqueous NaOH solution. The blue color of XL became red by ultraviolet irradiation, while XL was blue. It was estimated that the phenolic hydroxyl groups of XL were acylated by ultraviolet irradiation, because the acetyl XL was red. The effect of XL on the growth of Chinese Hamster Ovary cells was examined in the medium supplemented by XL. In the presence of XL, the cell growth in the medium was much retarded. The retardation was reduced when the irradiated XL was used

A case of synchronous double primary cancer of the lower gingiva and esophagus

A case of synchronous double cancers of the lower gingival and esophagus in a 60-year-old man is presented. The patient\u27s history, such as heavy smoking, overconsumption of alcohol suggested that he might have a high risk of synchronous double primary cancers. The lower gingival carcinoma was histologically diagnosed as squamous cell carcinoma and successfully treated with segmental mandibulectomy, radical neck dissection and reconstruction using free radial forearm flap. Gastrointestinal fiberscopy (GIF) was performed before treatment of the lower gingival cancer revealed esophageal superficial cancer. After the resection of lower gingival cancer and reconstruction, we conducted swallowing rehabilitation by the balloon method to widen the esophageal tract. Three months after completion of treatment for the lower gingival cancer, endoscopic submucosal dissection (ESD) for large superficial cancer of the esophagus was performed. It is was considered that examination of the upper gastrointestinal tract in the patients with oral and maxillofacial cancer by GIF and the postoperative swallowing rehabilitation were important for double primary cancers

Comprehensive analysis including the nutritional point of view on the pathogenesis of periodontal disease

To clarify risk factors for periodontal disease from the viewpoints of physiology, blood biochemistry, and nutrition, a survey involving 364 persons (224 males, 140 females) who consulted the Medical Examination Center of Matsumoto Dental University Hospital was conducted. The pathogenesis of periodontal disease was investigated using the maximum Community Periodontal Index (CPI) and Attachment Loss (AL) values, and their distributions with respect to the sex were analyzed using Wilcoxonʼs rank sum test. Based on the CPI and AL values, the subjects were divided into 3 groups: healthy (0), mild (1–2), and severe (3–4). The mean values obtained from the physiological, dental, blood biochemical, and nutritional findings in the 3 groups were analyzed using the multiple comparison test. Furthermore, their distributions with respect to sex and smoking in the 3 groups were analyzed using Fisherʼs direct probability test. A p–value of 0.05 was regarded as significant. Factors influencing the CPI included the sex (male), body mass index (BMI), abdominal circumference, diastolic blood pressure, AL, alanine aminotransferase (ALT), fasting blood glucose, neutral fat, HDL cholesterol, and smoking. Factors influencing the AL included the sex (male), age, current number of teeth, CPI, lipid intake, manganese intake, vitamin C intake, monounsaturated fatty acid intake, polyunsaturated fatty acid intake, n–6 fatty acid intake, fruit intake, and smoking. The results suggest that the physiological, blood biochemical, and nutritional states are involved in the pathogenesis of periodontal disease. The CPI was associated with metabolic error in the presence of metabolic syndrome. There was an association between the AL and diet as an environmental factor

Factors related to the number of missing teeth from a physiological, blood biochemical, and nutritional point of view

The aim of this study was to clarify the risk factors for tooth loss from a physiological, blood biochemical, and nutritional point of view. The subjects of this study were 364 people (224 males, 140 females). They were examinees of a medical examination center in Matsumoto Dental University Hospital. Using the number of teeth present (including sound, decayed, and filled teeth) as the response variable, a multiple regression analysis was conducted using parameters in the mouth, physiological parameters, blood biochemical parameters, and nutritional parameters as covariates. In the multiple regression analysis with the response variable as the number of teeth present, the significant influence of attachment loss, sugar–sweetener intake, age, and sodium intake was noted on a decreasing number of teeth in the study subjects. Thus, the number of teeth present was influenced by the physiological, blood biochemical, and nutritional condition. In the future, increasing the number of cases will be necessary along with long–term follow–up

Precise Measurement of Cosmic-Ray Proton and Helium Spectra with the BESS Spectrometer

We report cosmic-ray proton and helium spectra in energy ranges of 1 to 120 GeV and 1 to 54 GeV/nucleon, respectively, measured by a balloon flight of the BESS spectrometer in 1998. The magnetic-rigidity of the cosmic-rays was reliably determined by highly precise measurement of the circular track in a uniform solenoidal magnetic field of 1 Tesla. Those spectra were determined within overall uncertainties of +-5 % for protons and +- 10 % for helium nuclei including statistical and systematic errors.Comment: 12 pages, 4 figure