Modulation Recognition Method of Non-cooperation Underwater Acoustic Communication Signals Using Principal Component Analysis

由于信道传输特性、信噪比低等因素的影响,非合作水声通信信号的调制识别极具挑战性。对信号功率谱、平方谱进行主分量分析,提取代表不同类型调制信号特有信息的主分量作为特征参数,从而降低特征参数维度、抑制噪声影响,并在此基础上设计一种基于人工神经网络的水声通信信号调制方式分类器。海上实录信号数据的识别实验结果表明了该方法的有效性。The modulation classification of the non-cooperation underwater acoustic communication signals is extremely challenging due to channel transmission characteristics and low signal-to-noise ratio. The principal component analysis( PCA) is used to analyze the power spectra and square spectrum features of signals,which is capable of extracting the principal components associated with different modulated signals as input vector,thus reducing the feature dimension and suppressing the influence of noise. An artificial neural network( ANN) classifier is proposed for modulation recognition. The experimental modulation classification results obtained from field signals in 4 different underwater acoustic channels show that the proposed modulation recognition method has good classification performance.国家自然科学基金项目(11274259、11574258

Therapeutic Observation ofNa Zhi Method plus Electroacupuncture for Poststroke Uninhibited Neurogenic Bladder

目的 观察纳支法结合电针治疗中风后无抑制性神经源性膀胱的临床疗效.方法 将120例脑血管病变引起的无抑制性神经源性膀胱患者随机分为治疗组和对照组,每组60例.治疗组采用纳支法结合电针治疗;对照组采用电针疗法.每日1次,每次30 min,治疗2星期.观察两组治疗前后日排尿频率测试分度和膀胱最大容量的变化,并比较临床疗效.结果 治疗组总有效率为98.2%,愈显率为89.5%;对照组总有效率为93.1%,愈显率为72.4%.两组愈显率比较,差异有统计学意义（P〈0.05）.两组治疗前日排尿频率测试分度比较,差异无统计学意义（P〉0.05）;两组治疗前后日排尿频率测试分度比较,差异有极显著统计学意义（P〈0.01）;治疗组治疗后日排尿频率测试分度与对照组比较,差异有统计学性意义（P〈0.05）.两组治疗前膀胱最大容量比较,差异无统计学意义（P〉0.05）;两组治疗前后膀胱最大容量比较,差异有极显著统计学意义（P〈0.01）;治疗组治疗后膀胱最大容量与对照组比较差异有统计学意义（P〈0.05）.结论 电针治疗无抑制性神经源性膀胱疗效显著,结合纳支法疗效明显优于单纯电针.Objective To observe the clinical efficacy of Na Zhi method （midnight-noon ebb-flow method） plus electroacupuncture in treating poststroke uninhibited neurogenic bladder.Method A total of 120 patients with uninhibited neurogenic bladder due to cerebrovascular diseases were randomized into a treatment group and a control group, 60 cases in each group. The treatment group was intervened by Na Zhi method plus electroacupuncture; the control group was intervened by electroacupuncture. The intervention was conducted once a day, 30 min each time, for a total of 2 weeks. The daily voiding frequency index and maximum cystometric capacity （MCC） in the two groups were measured before and after the intervention, and the clinical efficacies were compared.Result The total effective rate and markedly effective rate were respectively 98.2% and 89.5% in the treatment group versus 93.1% and 72.4% in the control group. There was a significant difference in comparing the markedly effective rate between the two groups （P〈0.05）. There was no significant difference in comparing the daily voiding frequency index between the two groups before the intervention （P〉0.05）; the daily voiding frequency index was significantly changed after the intervention in both groups （P〈0.01）, and the daily voiding frequency index of the treatment group was significantly different from that of the control group after the intervention （P〈0.05）. There was no significant difference in comparing the MCC before the intervention between the two groups （P〉0.05）; the MCC was significantly changed after the intervention in both groups （P〈0.01）; the MCC of the treatment group was significantly different from that of the control group after the intervention （P〈0.05）.Conclusion Electroacupuncture can produce a significant efficacy in treating uninhibitedneurogenic bladder, while it can produce a more significant efficacy when combined withNa Zhi method

Research progress on osteoporotic vertebral collapse with delayed neurological deficits

随着世界人口老龄化,骨质疏松已成为一项全球化的健康问题。骨折是骨质疏松最严重的后果,而骨质疏松性椎体骨折是最常见的骨折类型。骨质疏松性椎体骨折大; 多数可通过保守治疗获得骨折愈合,但仍有约10%~ 30%并发骨折不愈合,并渐进性出现骨质疏松性椎体骨折塌陷(osteoporotic; vertebral collapse,OVC); 其中约3% 的OVC伴有迟发性神经损害(delayed neurological; deficits,DND)。有关OVC并发DND的具体机制以及其治疗策略,文献报道不尽相同。笔者就此相关问题综述如下

Experimental study on correlation of VEGF with corneal neovascular permeability after alkali burn

目的研究大鼠角膜碱烧伤后新生血管渗透率的变化并探讨血管内皮细胞生长常大鼠角膜作为对照。结果正常及碱烧伤后1d、2d、3d、5d、7d、10d大鼠角膜新生血管渗透率依次为0mg.L-1.mm-2,(1.14±0.17)mg.L-1.mm-2,(0.24±0.08)mg.L-1.mm-2,(0.29±0.16)mg.L-1.mm-2,(0.14±0.10)mg.L-1.mm-2,(0.09±0.06)mg.L-1.mm-2和(0.05±0.04)mg.L-1.mm-2;角膜组织中VEGF-RNA水平依次为(1.09±0.31)×106拷贝.μg-1总RNA,(7.01±1.99)×106拷贝.μg-1总RNA,(1.01±0.59)×106拷贝.μg-1总RNA,(2.43±0.43)×106拷贝.μg-1总RNA,(0.99±1.31)×106拷贝.μg-1总RNA,(0.95±0.03)×106拷贝.μg-1总RNA和(0.17±0.15)×106拷贝.μg-1总RNA,其中7d和10d的VEGF-RNA低于正常水平(P7=0.011,P10=0.006)。经Pearson相关分析,新生血管渗透率和VEGF-... 【英文摘要】 Objective To investigate the changes of neovascular permeability,and explore the effect of vascular endothelial growth factor(VEGF)on it after alkali burn.Methods The rat model of alkali burn induced corneal neovascularization(CNV)was constructed.Neovascular permeability was measured by Evans blue method at 1 day,2 days,3 days,5 days,7 days and 10 days after surgery,respectively.Expression of vascular endothelial growth factor(VEGF)was evaluated using real time PCR.Normal corneas were treated as control gro...国家杰出青年科学基金资助(编号:30225044);; 广州市卫生局科学基金资助(编号:2008-YB-053)~

Design and manufacture of array sphygmology sensor

提出了一种用微机电系统(MEMS)技术应变传感器阵列探头客观细腻地采集人体脉象的新思路。探头采用直接腐蚀出电阻条的技术,具有工艺简单、成本低廉、电阻变化率高、工作可靠等优点。对设计进行了理论计算和优化,并用有限元分析软件ANSYS8.0进行了结构和电耦合场仿真,模拟悬臂梁端点位移对电阻变化的影响。当悬臂梁末端位移变化为50μm时,电阻变化率模拟结果为18.84%,与理论计算值19.67%符合得很好。For acquiring more comprehensive information of pulse conditions,a probe of pulse symbol instrument designed by MEMS technology has been presented,the method of direct etching of silicon is utilized to form the resistor.The process is simple,economical,and it has high change rate of resistor,working reliability.After theory calculation,the coupled-field analyses between the structural and electric fields are carried out by finite element analysis software ANSYS 8.0.It simulates the change of resistor with the displacement of cantilever tip.When the tip of cantilever displaces 50μm,the modulation result is 18.84%,and is in good agreement with the calculation result of 19.67%

Preparation of Immobilized Nucleoside Phosphorylase and Research on Its Property

目的优化核苷磷酸化酶的固定化工艺,并对固定化酶的性质进行研究。方法通过正交试验优化核苷磷酸化酶(包括嘌呤和嘧啶核苷磷酸化酶)固定化条件,并进一步对固定化核苷磷酸化酶的最适P H、温度及其稳定性进行研究。结果固定化酶条件为P H=8.0,温度为25℃,蛋白载量为20 Mg/g载体,固定化时间为6 H;固定化核苷磷酸化酶的最适P H=7.5,最适温度为40℃,固酶连续使用20批次酶活力无明显损失。结论固定化核苷磷酸化酶稳定可靠,适合应用于工业化生产。Objective To optimize the immobilization process of the nucleoside phosphorylase and research on its property.Methods The immobilization process of the nucleoside phosphorylase(including purine and pyrimidine nucleoside phosphorylase)was optimized by orthogonal test,and took further study of the finest p H,temperature and stability of immobilized nucleoside phosphorylase.Results The finest condition of immobilized enzyme was p H = 8.0,25 ℃,20 mg/g protein loads and immobilize for 6 h; the finest condition for the immobilized nucleoside phosphorylase to catalyze was p H = 7.5 and 40 ℃.There was no significant loss of activity of the enzyme after use for catalyzing 20 batches consecutively.Conclusion The immobilized nucleoside phosphorylase is stable and reliable,which is suitable to application in industrial productio

23-乙酰泽泻醇B对2型糖尿病小鼠血糖的影响

目的 探讨23-乙酰泽泻醇B是否有治疗2型糖尿病的潜能。方法 通过腹腔注射链脲佐菌素和烟酰胺建立2型糖尿病小鼠模型。灌胃罗格列酮或23-乙酰泽泻醇B 3周后,测定2型糖尿病小鼠血糖值,次日进行口服葡萄糖耐受试验（OGTT）。采用葡萄糖荧光示踪剂,测定23-乙酰泽泻醇B对葡萄糖吸收的影响。采用3T3-L1前脂肪细胞分化模型,测定其对分化的影响。结果 分别每天灌胃阳性药罗格列酮10 mg·kg-1、23-乙酰泽泻醇B(5、10、20 mg·kg-1),连续灌胃给药3周后,降低了2型糖尿病小鼠血糖值,一定程度改善OGTT过程中胰岛素抵抗。在30 mmol·L-1高糖条件下,23-乙酰泽泻醇B促进了脂肪细胞对胰岛素刺激的葡萄糖吸收; 23-乙酰泽泻醇B(1、10μmol·L-1)促进3T3-L1前脂肪细胞的分化过程。结论 23-乙酰泽泻醇B降低2型糖尿病小鼠血糖,促进前脂肪细胞分化,促进脂肪细胞吸收葡萄糖,但作用机制仍需进一步探索。国家自然科学基金面上项目(No 81773601);;福建省卫生系统中青年骨干人才培养项目(No 2015-ZQN-JC-45);;福建省教育厅中青年教师教育科研项目(No JT180664

脊柱骨盆矢状面形态与青少年腰椎间盘突出症的关系研究

目的:探讨导致青少年腰椎间盘突出症(Adolescent Lumbar Disc Herniation,ALDH)的脊柱骨盆矢状面关键参数,明确不同腰椎Roussouly分型与腰椎间盘突出症的关系。方法:回顾性研究2014年1月至2017年6月在本院骨科诊治ALDH患者32例(ALDH组),同时选择中老年腰椎间盘突出症患者(中老年组)、年龄和性别匹配的正常青少年志愿者(对照组)各32例。在站立位全脊柱侧位X线片上统计腰椎Roussouly分型,并测量腰椎前凸角(Lumbar Lordosis,LL)、骨盆投射角(Pelvic Incidence,PI)、骨盆倾斜角(Pelvic Tilt,PT)和骶骨倾斜角(Sacral Slope,SS),对ALDH组、中老年组和对照组三组间的影像学指标和Roussouly分型进行比较。结果:ALDH组PI为52.0°±13.3°和PT为25.3°±14.5°均显著大于对照组45.2°±8.0°和15.1°±9.3°,差异有统计学意义(P0.05);Roussouly分型在ALDH组和对照组间差异无统计学意义(P>0.05)。结论:较大的PI更易导致青少年腰椎间盘突出症的发生。与中老年腰椎间盘突出症患者相比,ALDH患者腰椎前凸角更小,骶骨终板更加水平,Roussouly分型以2型居多,而4型较少。福建省自然科学基金(2018J01362);;福州市科技计划项目(2016-S-123-17