环孢素治疗中重度干眼症的对照研究

【目的】观察0．2％（2g/L）环孢素滴眼液对中重度干眼症的效果。【方法】将中重度干眼症134例随机分为对照组（65例）和实验组（69例）。对照组应用10g/L羧甲基纤维素钠，4次／d，实验组应用10g/L羧甲基纤维素钠和2g／L环孢素滴眼液，4次/d。两组均连续用药1个月。用药前后均进行荧光素染色检查、泪液分泌检查（STT）、泪膜破裂时间检测（BUT）、结膜印迹细胞检查。【结果】两组比较在治疗前差异无统计学意义（P〉0．05），治疗后实验组SIT、BUT比对照组的结果有统计学意义（P〈0．01），实验组治疗前后结果比较有统计学意义（P〈0．01）。对照组的治疗前后比较差异无统计学意义（P〉0．05）。【结论】2g/L环孢素滴眼液治疗中重度干眼确有良好的效果

Assessing ecological risks of heavy metals to marine organisms in the Jiulongjiang Estuary by species sensitivity distribution

采用物种敏感性分布法(SSd)构建常见重金属元素对海洋生物的SSd曲线,结合九龙江口水体5、8、11月份21个站位重金属调查数据,计算了九龙江口7种重金属(AS,Cd,Cr,Cu,Hg,Pb,zn)不同暴露浓度对海洋生物的潜在影响比例(PAf),并分析了在相应站位重金属复合污染生态风险(MSPAf)。结果表明,7种重金属中AS的生态风险最大(即PAf值最高);时间尺度上,5月份总的MSPAf较其他月份稍高;空间尺度上,西溪至海门岛(1~7号站位)污染较严重,其中又以位于西溪和玉枕洲的2号和5号站位的MSPAf为最。In the present work,a species sensitivity distribution( SSD) method was used to assess the ecological risk of common heavy metals to marine organisms.The ecological risk was characterized by potentially affected fraction( PAF) of species in relation to concentration of the toxic materials.According to the investigation data obtained at 21 stations in the Jiulongjiang Estuary in May,August and November,the PAFs of seven heavy metals( As,Cd,Cr,Cu,Hg, Pb,and Zn) to marine organisms were calculated.The results showed that As had the highest PAF among the seven heavy metals at each station of the Jiulongjiang Estuary.Spatially,the multi-substance PAF( msPAF) in May was higher than in other months.Temporally,the msPAF of the Stations 1-7( from the Xixi Stream to the Haimen Isle of the Jiulongjiang Estuary) suffered from heavier pollution.In particular,the pollution status of the Station 2 and Station 5 was the most serious among all the investigated stations.海洋公益性行业科研经费专项(201105015); 国家海洋局青年海洋科学基金项目(2011143); 国家自然科学基金项目(31101902); 福建省自然科学基金项目(2012J05074); 国家海洋局第三海洋研究所基本科研业务费专项(海三科2011006)资

Study on the Synthesis and Curing of Waterborne Epoxy-acrylate Grafted Copolymers

环氧树脂与丙烯酸类单体接枝共聚是制备水性环氧树脂的一条重要途径.本文作者研究了多元接枝水性环氧树脂的合成,及其与固化剂双氰胺的固化工艺.讨论了单体配比、接枝反应温度、反应时间等因素对水性环氧乳液接枝率的影响,确定了较佳的工艺条件,通过红外光谱分析证实了丙烯酸接枝环氧共聚物的结构,并考察了漆膜的固化条件.所得涂膜附着力、柔韧性、硬度很好,能达到溶剂型环氧树脂防腐蚀涂料水平.The waterborne multi-graft epoxy resin is based on epoxy resin as parents,and α-methacrylic acid,styrene and butyl acrylate as grafted monomers with BPO as initiator,the synthesis of grafting epoxy copolymer and its curing by dicyandiamide have been studied in this paper,The reaction conditions affecting the grafting ratio of emulsion,such as the ratio of grafting monomers、grafting reaction temperature and reaction time were discussed,The results showed that when the ratio of α-methacrylic acid/ styrene/ butyl acrylate was 1564,grafting reaction temperature was 110℃～115℃,reaction time was 6h,the epoxy emulsion with most stability and highest grafting ratio would be obtainded.The structure of grafting epoxy copolymer is proved by analyzing infrared spectrum(IR).The conditions of curing were also investigated.A series of coating films of different curing temperature and quantity of DICY were prepared,the optimum conditions of curing were determined by testing degree of cross linking of the coating films and the coating films properties.The results showed that when the curing technics was 140℃/1h,and the mol ratio of epoxy group/ amino hydrogen of DICY was 10.4,the coating films have good properties of adhesion、flexibility and hardness,and it reach the standard of corrosion resistant solvent-borne epoxy coatings

An investigation of depression and anxiety of the victims after Yushu earthquake

目的分析研究地震灾害对灾区患者抑郁焦虑的影响。方法采用抑郁自评和焦虑自评量表对住院灾区患者进行调查与评定,与中国成年常模相比较,分析观察指标的相关性。结果 155例灾区患者中抑郁、焦虑情绪的发生率分别为87.09%和53.55%;灾区患者存在一定程度的焦虑、抑郁状况,与文化程度、收入状况、汉语程度、受伤情况及有无陪员相关。结论在临床救治过程中,应考虑到文化程度、收入状况、汉语程度、受伤情况及有无陪员等因素。Objective To study the earthquake-caused depression and anxiety on the disasterstricken victims.Methods Self-rating depression scale and self-rating anxiety scale were used to investigate and evaluate the victims by comparing with Chinese norm and relevant observation factors.Results The incidence of depression and anxiety were 87.09%and 53.55%.Patients have some degree of anxiety and depression.The condition was related to educational level,income, language level,injury degrees and members accompanied.Conclusion In the course of clinical treatment and care,these factors are the essential ones to be considered.甘肃省技术研究与开发专项计划项目(1004TCYA009

卡尔曼滤波辅助色谱分析法的研究与应用——Ⅰ.色谱重叠峰的分辨

<正> 色谱方法系广泛应用于分析化学、生物医学、环境科学等领域中重要而有效的工具。在进行结构及性质极为相近的物质分离分析时,常遇到谱图重叠的现象。为解决诸类问题,采用垂线法、切线法等进行色谱定量较为简便直观,仅

Study of Sea-island Fibers Structure and Their Dyeing Properties

通过色差仪、DSC、结晶速度测量、显微图像分析以及动态机械热分析研究了四种海岛纤维的结晶度、结晶速度、晶粒大小、玻璃化温度与染色性能的关系.结果表明:结晶度小,结晶速度慢,晶粒尺寸大,玻璃化温度低等等均有利于纤维染色性能的提高.Dyeing is one of the biggest problems of sea-island fibers.It is well known that dyeing quality of industrial poly ethylene terephthalate(PET) yarns can be greatly influenced by the physical and structural properties of the yarns.In order to evaluate the effect of physical and structural properties on dyeing performance of sea-island fibers,this article dealt with four commercially available sea-island super micro fibers,whose main component were PET and the specifications were 105/48*37i,105/48*25i,105/36*37i,and 105/36*37i~*;their chromatic differences were characterized and compared using a color difference meter;and subsequently the different physical and structural factors that may affect the dyeing performance,such as the glass-transition temperature,the degree of crystallinity,the crystallization rate,and the grain size of these fibers,were investigated.The relationship between dyeing performance and these factors was studied.Differential scanning calorimetry(DSC) revealed that low degree of crystallinity exerted favorable influence on dyeing.Crystallization detector suggested that dyeing quality was improved as crystallization rate decreased.When these fibers were observed under polarizing microscope,it showed that good dyeing quality was related to big grain size.The results of the dynamic mechanical thermo analysis(DMTA) showed that fibers with low glass-transition temperature tended to yield good dyeing quality because of the molecular motion