Allergen immunotherapy in the polyallergic adolescent

Allergen immunotherapy is the only disease-modifying treatment option for allergic rhinitis, with adherence being its major limitation. We report a case of an adolescent with rhinitis, proven allergy to multiple non-homologous pollens, and troublesome symptoms despite maximal symptomatic therapy during the late spring and early summer months. Allergen immunotherapy to the most clinically relevant allergen was initiated under the supervision of a pediatrician. Shortly before her second year of treatment, she transferred to adult care and maintained a high degree of adherence and a favourable response to immunotherapy. In conclusion, allergen immunotherapy is effective in polyallergic adolescents with good adherence

Acute exacerbations of chronic obstructive lung disease

Akutne egzacerbacije kronične opstruktivne plućne bolesti (KOPB) definirane su akutnim pogoršanjem respiratornih simptoma koje zahtijevaju dodatno liječenje, a pritom stupanj zaduhe nadmašuje uobičajenu razinu uz povećan volumen i/ili purulenciju iskašljaja. Najčešći uzrok akutnih egzacerbacija KOPB-a su virusne, nešto rjeđe bakterijske ili miješane infekcije. Bolesnici s fenotipom učestalog egzacerbatora koji su tijekom prethodnih dvanaest mjeseci liječeni od najmanje dvije umjerene ili jedne teške egzacerbacije imaju znatno lošiju kvalitetu života i ubrzano propadanje plućne funkcije. Više od 80% akutnih egzacerbacija moguće je liječiti ambulantno bronhodilatatorima, oralnim kortikosteroidima i/ili antibiotikom.Acute exacerbations of chronic obstructive lung disease (COPD) are defined as episodes of increased respiratory symptoms, particularly dyspnea, sputum volume and purulence, requiring additional therapy. Acute exacerbations are mostly induced by viral, less often bacterial or mixed infections. Patients with two or more exacerbations treated in the outpatient department (or at least one hospitalisation for acute exacerbation) are considered as frequent exacerbators – the phenotype associated with poorer quality of life and accelerated loss of lung function. More than 80% of acute exacerbations can be treated in the outpatient setting with bronchodilators, short-course of oral corticosteroids and/or antibiotics

Acute exacerbations of chronic obstructive lung disease

Akutne egzacerbacije kronične opstruktivne plućne bolesti (KOPB) definirane su akutnim pogoršanjem respiratornih simptoma koje zahtijevaju dodatno liječenje, a pritom stupanj zaduhe nadmašuje uobičajenu razinu uz povećan volumen i/ili purulenciju iskašljaja. Najčešći uzrok akutnih egzacerbacija KOPB-a su virusne, nešto rjeđe bakterijske ili miješane infekcije. Bolesnici s fenotipom učestalog egzacerbatora koji su tijekom prethodnih dvanaest mjeseci liječeni od najmanje dvije umjerene ili jedne teške egzacerbacije imaju znatno lošiju kvalitetu života i ubrzano propadanje plućne funkcije. Više od 80% akutnih egzacerbacija moguće je liječiti ambulantno bronhodilatatorima, oralnim kortikosteroidima i/ili antibiotikom.Acute exacerbations of chronic obstructive lung disease (COPD) are defined as episodes of increased respiratory symptoms, particularly dyspnea, sputum volume and purulence, requiring additional therapy. Acute exacerbations are mostly induced by viral, less often bacterial or mixed infections. Patients with two or more exacerbations treated in the outpatient department (or at least one hospitalisation for acute exacerbation) are considered as frequent exacerbators – the phenotype associated with poorer quality of life and accelerated loss of lung function. More than 80% of acute exacerbations can be treated in the outpatient setting with bronchodilators, short-course of oral corticosteroids and/or antibiotics

Skin and lung tuberculosis in patients with mixed connective disease - case report

Cilj ovoga rada je prikazati rijedak slučaj kožne i plućne tuberkuloze (TBC) u bolesnice s miješanom bolesti vezivnoga tkiva na imunosupresivnoj terapiji, kako bi se ukazalo na važnost rane dijagnostike, liječenja i prevencije komplikacija bolesti. TBC je zarazna bolest uzrokovana bacilom Mycobacterium tuberculosis (MT). Prenosi se kapljičnim putem u kontaku s oboljelom osobom, dok su drugi oblici prijenosa izuzetno rijetki. S obzirom na lokalizaciju, bolest se dijeli se na plućnu i izvanplućnu TBC. 15% svih slučajeva TBC-a čine izvanplućni oblici, dok je kožna TBC rijedak izvanplućni oblik koja čini 0.5-2% svih izvanplućnihih TBC-a u razvijenim zemljama. Čimbenici koji pridonose razvoju i progresiji TBC-a su alkoholizam, loša ishrana, šećerna bolest, infekcija virusom humane imunodeficijencije (HIV)/sindrom stečene imunodeficijencije (AIDS), razvoj transplantacijske medicine, kronični program hemodijalize, sve veće liste bolesti i stanja koja zahtijevaju primjenu imunosupresivne terapije. Široki spektar simptoma i znakova TBC-a česti su uzrok nepravovremeno postavljenoj dijagnozi, što odgađa adekvatno liječenje, povećava broj i mogućnost komplikacija, te u konačnici dovodi do povećanja mortaliteta. U ovom prikazu slučaja bolesnica je razvila kožni i plućni oblik TBC-a, a dijagnoza je postavljena tek nakon deset mjeseci od razvoja prvih simptoma. Provedeno je liječenje antituberkuloznim lijekovima (ATL) (izoniazid, rifampicin, etambutol, pirazinamid) u trajanju od godinu dana, nakon čega je došlo do potpune regresije kožnih promjena, kao i radiološkog nalaza plućnog infiltrata.The aim of this paper is to present a rare case of skin and pulmonary tuberculosis (TB) in a patient with mixed connective tissue disease on immunosuppressive therapy and to point the importance of early diagnosis, treatment and prevention of complications of the disease. TB is a contagious disease caused by Mycobacterium tuberculosis (Mtb). It is transmitted via droplets from an infected person, while other transmission modes are extremely rare. Due to localization, the disease is divided into pulmonary and extrapulmonary TB.15% of all cases of TB are extrapulmonary forms while skin TB is a rare extrapulmonary form that makes up 0.5-2% of all extrapulmonary TB in developed countries. Factors contributing to the development and progression of TB are alcoholism, poor nutrition, diabetes, human immunodeficiency virus (HIV) infection/ acquired immunodeficiency syndrome (AIDS), development of transplantation medicine, chronic hemodialysis program and an increasing list of diseases and conditions requiring the use of immunosuppressive therapy. A wide range of symptoms and signs of tuberculosis postpone its diagnosis which delays adequate treatment, increases the number and possibility of complications, and ultimately leads to an increase in mortality. In this case report, the patient developed skin and pulmonary TB and the diagnosis was established ten months after the development of the first symptom. After a year of antituberculosis therapy (isoniazid, rifampicin, ethambutol, pyrazinamide), a complete regression of skin changes occurred as well as radiological findings of pulmonary infiltrates

Skin and lung tuberculosis in patients with mixed connective disease - case report

Cilj ovoga rada je prikazati rijedak slučaj kožne i plućne tuberkuloze (TBC) u bolesnice s miješanom bolesti vezivnoga tkiva na imunosupresivnoj terapiji, kako bi se ukazalo na važnost rane dijagnostike, liječenja i prevencije komplikacija bolesti. TBC je zarazna bolest uzrokovana bacilom Mycobacterium tuberculosis (MT). Prenosi se kapljičnim putem u kontaku s oboljelom osobom, dok su drugi oblici prijenosa izuzetno rijetki. S obzirom na lokalizaciju, bolest se dijeli se na plućnu i izvanplućnu TBC. 15% svih slučajeva TBC-a čine izvanplućni oblici, dok je kožna TBC rijedak izvanplućni oblik koja čini 0.5-2% svih izvanplućnihih TBC-a u razvijenim zemljama. Čimbenici koji pridonose razvoju i progresiji TBC-a su alkoholizam, loša ishrana, šećerna bolest, infekcija virusom humane imunodeficijencije (HIV)/sindrom stečene imunodeficijencije (AIDS), razvoj transplantacijske medicine, kronični program hemodijalize, sve veće liste bolesti i stanja koja zahtijevaju primjenu imunosupresivne terapije. Široki spektar simptoma i znakova TBC-a česti su uzrok nepravovremeno postavljenoj dijagnozi, što odgađa adekvatno liječenje, povećava broj i mogućnost komplikacija, te u konačnici dovodi do povećanja mortaliteta. U ovom prikazu slučaja bolesnica je razvila kožni i plućni oblik TBC-a, a dijagnoza je postavljena tek nakon deset mjeseci od razvoja prvih simptoma. Provedeno je liječenje antituberkuloznim lijekovima (ATL) (izoniazid, rifampicin, etambutol, pirazinamid) u trajanju od godinu dana, nakon čega je došlo do potpune regresije kožnih promjena, kao i radiološkog nalaza plućnog infiltrata.The aim of this paper is to present a rare case of skin and pulmonary tuberculosis (TB) in a patient with mixed connective tissue disease on immunosuppressive therapy and to point the importance of early diagnosis, treatment and prevention of complications of the disease. TB is a contagious disease caused by Mycobacterium tuberculosis (Mtb). It is transmitted via droplets from an infected person, while other transmission modes are extremely rare. Due to localization, the disease is divided into pulmonary and extrapulmonary TB.15% of all cases of TB are extrapulmonary forms while skin TB is a rare extrapulmonary form that makes up 0.5-2% of all extrapulmonary TB in developed countries. Factors contributing to the development and progression of TB are alcoholism, poor nutrition, diabetes, human immunodeficiency virus (HIV) infection/ acquired immunodeficiency syndrome (AIDS), development of transplantation medicine, chronic hemodialysis program and an increasing list of diseases and conditions requiring the use of immunosuppressive therapy. A wide range of symptoms and signs of tuberculosis postpone its diagnosis which delays adequate treatment, increases the number and possibility of complications, and ultimately leads to an increase in mortality. In this case report, the patient developed skin and pulmonary TB and the diagnosis was established ten months after the development of the first symptom. After a year of antituberculosis therapy (isoniazid, rifampicin, ethambutol, pyrazinamide), a complete regression of skin changes occurred as well as radiological findings of pulmonary infiltrates

8th international scientific conference on kinesiology: 20th anniversary : proceedings

We are exceptionally happy that we can greet you once more on this occasion. The Faculty of Kinesiology, as a proud member of the University of Zagreb and a higher education institution that is 57 years old, is organizing The International Scientific Conference on Kinesiology for the 8th time. Identically as three years ago, this is a good opportunity to remember some important anniversaries. First of all, this year we celebrate 160 years since Nicolas Dally published his work in 1857 under the title “Kinesiology – Science of Movement in Relation to Education, Hygiene and Therapy”. This was the first book that introduced Kinesiology as a science of movement. The second important anniversary is 20 years since the establishment of our Conference. In 1997 the first International Scientific Conference on Kinesiology was held in Dubrovnik. Until today a great number of leading experts in the field of contemporary kinesiology were keynote lectures and presenters of the most important scientific breakthroughs in the field. Once again, the Conference will be a great opportunity for broadening of scientific insights into this miraculous, beautiful phenomenon of physical activity and its effects – its perfection when performed by sport artists, as seen at the XXXI Olympic Games, its joyfulness when happy children enjoy being competent to be in motion, or when we see eager people who enjoy life and nature because they have enough energy and they are healthy thanks to an active lifestyle. We are especially proud of the 17th place on the medal list thanks to the ten Olympic medals won by Croatian athletes. All fundamental and applied fields of our science will be discussed within 10 tentative sessions and 3 Satellite symposiums. The ultimate purpose of papers or abstracts published in this Proceedings book is to know and understand human beings and to apply the findings in everyday practice of education, sports, health promotion, recreation, sports management and kinesitherapy. The Proceedings Book contains 249 contributions, which were submitted by the submission deadline, written by 557 authors from 30 countries from all over the world. We expect a number of graduate, doctoral and postdoctoral students from Croatia and abroad for whom the Conference School of Kinesiology for Postgraduate and Doctoral Students will be organised during the Conference. From the very beginning the Croatian Academy of Sciences and Arts has given its highly respected patronage to the Conference, thus underpinning the recognition of kinesiology in the structure of sciences. Special thanks go to our partner institutions: Beijing Sports University, China and the Faculty of Sports Studies, Masaryk University, Brno, Czech Republic, to our collaboration institutions: the Lithuanian University of Educational Sciences, Lithuania, the Otto-von-Guericke University, Magdeburg, Germany and the Faculty of Sport and Physical Education, University of Novi Sad, Serbia. We wish to express much gratitude to all the authors, reviewers, participants, members of the Organisation and Program Committee, Section Editors, technical support staff, and sponsors for their contributions, time and effort inbuilt in the quality of the 8th International Conference on Kinesiology and its Proceedings. We wish success in the conference work to all the participants and a pleasant time in Opatija. Convinced that the Conference will give the expected impetus to further cooperation between scholars and institutions, we are looking forward in advance to meeting you again at the 9th International Conference on Kinesiology in 2020. Organising Committe

8th international scientific conference on kinesiology: 20th anniversary : proceedings

We are exceptionally happy that we can greet you once more on this occasion. The Faculty of Kinesiology, as a proud member of the University of Zagreb and a higher education institution that is 57 years old, is organizing The International Scientific Conference on Kinesiology for the 8th time. Identically as three years ago, this is a good opportunity to remember some important anniversaries. First of all, this year we celebrate 160 years since Nicolas Dally published his work in 1857 under the title “Kinesiology – Science of Movement in Relation to Education, Hygiene and Therapy”. This was the first book that introduced Kinesiology as a science of movement. The second important anniversary is 20 years since the establishment of our Conference. In 1997 the first International Scientific Conference on Kinesiology was held in Dubrovnik. Until today a great number of leading experts in the field of contemporary kinesiology were keynote lectures and presenters of the most important scientific breakthroughs in the field. Once again, the Conference will be a great opportunity for broadening of scientific insights into this miraculous, beautiful phenomenon of physical activity and its effects – its perfection when performed by sport artists, as seen at the XXXI Olympic Games, its joyfulness when happy children enjoy being competent to be in motion, or when we see eager people who enjoy life and nature because they have enough energy and they are healthy thanks to an active lifestyle. We are especially proud of the 17th place on the medal list thanks to the ten Olympic medals won by Croatian athletes. All fundamental and applied fields of our science will be discussed within 10 tentative sessions and 3 Satellite symposiums. The ultimate purpose of papers or abstracts published in this Proceedings book is to know and understand human beings and to apply the findings in everyday practice of education, sports, health promotion, recreation, sports management and kinesitherapy. The Proceedings Book contains 249 contributions, which were submitted by the submission deadline, written by 557 authors from 30 countries from all over the world. We expect a number of graduate, doctoral and postdoctoral students from Croatia and abroad for whom the Conference School of Kinesiology for Postgraduate and Doctoral Students will be organised during the Conference. From the very beginning the Croatian Academy of Sciences and Arts has given its highly respected patronage to the Conference, thus underpinning the recognition of kinesiology in the structure of sciences. Special thanks go to our partner institutions: Beijing Sports University, China and the Faculty of Sports Studies, Masaryk University, Brno, Czech Republic, to our collaboration institutions: the Lithuanian University of Educational Sciences, Lithuania, the Otto-von-Guericke University, Magdeburg, Germany and the Faculty of Sport and Physical Education, University of Novi Sad, Serbia. We wish to express much gratitude to all the authors, reviewers, participants, members of the Organisation and Program Committee, Section Editors, technical support staff, and sponsors for their contributions, time and effort inbuilt in the quality of the 8th International Conference on Kinesiology and its Proceedings. We wish success in the conference work to all the participants and a pleasant time in Opatija. Convinced that the Conference will give the expected impetus to further cooperation between scholars and institutions, we are looking forward in advance to meeting you again at the 9th International Conference on Kinesiology in 2020. Organising Committe