Spiritualità di Anthony de Mello

Služeći se metodom analize, autor razlaže duhovnost Anthonuja de Mella koja Je usko vezana za Čovjeka na putu (egzistencijalna duhovnost). No, ona nije ništa manje ni duhovnost koja govori o vječnim vrijednostima. Upravo to svakodnevno s čim se susreće čovjek i čiji Je dio i ono vječno za čim čovjek neprestano i na različite načine traga, u duhovnosti Anthonya de Mella našli su se zajedno.Seguendo metodo analitico, Tautore espone la spiritualita di Anthony de Mello la quale e sttretamente legata ali\u27 uomo in cammino (la spiritualita esistenziale). Ma, questa non e tanto meno la spiritualita dei valori eter ni. Nella spiritualita di Anthony de Mello si trova insieme quello che Tuomo incontra nella sua quotidianita e quell\u27eterno che Fuomo continuamente a diversi modi sta cercando

Effect of Disorder and Notches on Crack Roughness

We analyze the effect of disorder and notches on crack roughness in two dimensions. Our simulation results based on large system sizes and extensive statistical sampling indicate that the crack surface exhibits a universal local roughness of $\zeta_{loc} = 0.71$ and is independent of the initial notch size and disorder in breaking thresholds. The global roughness exponent scales as $\zeta = 0.87$ and is also independent of material disorder. Furthermore, we note that the statistical distribution of crack profile height fluctuations is also independent of material disorder and is described by a Gaussian distribution, albeit deviations are observed in the tails.Comment: 6 pages, 6 figure

Crack Roughness in the 2D Random Threshold Beam Model

We study the scaling of two-dimensional crack roughness using large scale beam lattice systems. Our results indicate that the crack roughness obtained using beam lattice systems does not exhibit anomalous scaling in sharp contrast to the simulation results obtained using scalar fuse lattices. The local and global roughness exponents ($\zeta_{loc}$ and $\zeta$, respectively) are equal to each other, and the two-dimensional crack roughness exponent is estimated to be $\zeta_{loc} = \zeta = 0.64 \pm 0.02$. Removal of overhangs (jumps) in the crack profiles eliminates even the minute differences between the local and global roughness exponents. Furthermore, removing these jumps in the crack profile completely eliminates the multiscaling observed in other studies. We find that the probability density distribution $p(\Delta h(\ell))$ of the height differences $\Delta h(\ell) = [h(x+\ell) - h(x)]$ of the crack profile obtained after removing the jumps in the profiles follows a Gaussian distribution even for small window sizes ($\ell$).Comment: 8 pages, 6 figure

Health care in Bosnia and Herzegovina before, during, and after 1992–1995 war: a personal testimony

Market-based health care reform during democratic transition in Bosnia and Herzegovina was complicated by the 1992–1995 war, that devastated the country and greater part of its health care infrastructure. The course of the transition and consequences of war for the health system and health professionals are presented here from the perspective of the author. The description of real-life situations and their context is used to illustrate the problems physicians, as well as international community, were faced with and how they tried to cope with them during and after the war. Speaking openly about the mistakes that were made in those times is the first step in preventing them from happening again and an invitation for exchange of opinions and open academic discussion

Replication of fifteen loci involved in human plasma protein N-glycosylation in 4,802 samples from four cohorts

Human protein glycosylation is a complex process, and its in vivo regulation is poorly understood. Changes in glycosylation patterns are associated with many human diseases and conditions. Understanding the biological determinants of protein glycome provides a basis for future diagnostic and therapeutic applications. Genome-wide association studies (GWAS) allow to study biology via a hypothesis-free search of loci and genetic variants associated with a trait of interest. Sixteen loci were identified by three previous GWAS of human plasma proteome N-glycosylation. However, the possibility that some of these loci are false positives needs to be eliminated by replication studies, which have been limited so far. Here, we use the largest set of samples so far (4,802 individuals) to replicate the previously identified loci. For all but one locus, the expected replication power exceeded 95%. Of the sixteen loci reported previously, fifteen were replicated in our study. For the remaining locus (near the KREMEN1 gene) the replication power was low, and hence replication results were inconclusive. The very high replication rate highlights the general robustness of the GWAS findings as well as the high standards adopted by the community that studies genetic regulation of protein glycosylation. The fifteen replicated loci present a good target for further functional studies. Among these, eight genes encode glycosyltransferases: MGAT5, B3GAT1, FUT8, FUT6, ST6GAL1, B4GALT1, ST3GAL4, and MGAT3. The remaining seven loci offer starting points for further functional follow-up investigation into molecules and mechanisms that regulate human protein N-glycosylation in vivo

New Paradigm in Training of Undergraduate Clinical Skills: the NEPTUNE-CS project at the Split University School of Medicine

Clinical skills’ training is arguably the weakest point in medical schools’ curriculum. This study briefly describes how we at the Split University School of Medicine cope with this problem. We consider that, over the last decades, a considerable advancement in teaching methodologies, tools, and assessment of students has been made. However, there are many unresolved issues, most notably: (i) the institutional value system, impeding the motivation of the teaching staff; (ii) lack of a strong mentoring system; (iii) organization, timing, and placement of training in the curriculum; (iv) lack of publications pertinent to training; and (v) unwillingness of patients to participate in student training. To improve the existing training models we suggest increased institutional awareness of obstacles, as well as willingness to develop mechanisms for increasing the motivation of faculty. It is necessary to introduce changes in the structure and timing of training and to complement it with a catalog, practicum, and portfolio of clinical skills. At Split University School of Medicine, we developed a new paradigm aimed to improve the teaching of clinical skills called “Neptune-CSS,” which stands for New Paradigm in Training of Undergraduate Clinical Skills in Split