545 research outputs found
\u3cem\u3eIn Vitro\u3c/em\u3e Evaluation of Different Protocols for Preventing Microleakage of Fissure Sealants Placed Following Saliva Contamination
Purpose: To evaluate the effect of different enamel conditioning protocols and their re-application on the microleakage of fissure sealants placed following saliva contamination.
Study design: The study included 156 human third molars in 16 subgroups (2×4×2) under two main groups (sealant type): Group A- hydrophobic resin sealant, 3M Clinpro™ Sealant; Group B- hydrophilic resin sealant, Ultraseal XT Hydro. Each group was then divided according to the type of surface conditioning; 1- Er,Cr:YSSG laser etching, 2- acid-etching, 3- acid-etching+etch-and-rinse adhesive (Prime&Bond® One Select) and 4- self-etching adhesive (Clearfil™SE Bond). After contaminating the conditioned occlusal enamel surfaces with artificial saliva, fissure sealant was applied in half of the specimens (a), whereas in the other half, (b) the respective surface conditioning was repeated and then fissure sealant was placed. Following thermocycling, the samples were immersed in basic fuchsin, sectioned, and dye penetration was quantitatively assessed with ImageJ. Two-way ANOVA and Bonferroni post-hoc tests were used for statistical analyses (p
Results: The least microleakage was observed in A3b and A3a, whereas B4b and B4a were the subgroups with the highest microleakage. Following saliva contamination, when surface conditioning was not re-applied, the effects of fissure sealant types and surface conditioning were significant (p=0.005 and p
Conclusions: 3M Clinpro™ Sealant was superior to Ultraseal XT Hydro. Re-application of Er,Cr:YSSG laser and the self-etching adhesive did not affect the microleakage of both fissure sealants. Without re-application, acid-etching+etch-and-rinse adhesive was superior to acid-etching only. However, both of them were similarly successful when they were re-applied following saliva contamination
Non-relativistic ten-dimensional minimal supergravity
We construct a non-relativistic limit of ten-dimensional N=1 supergravity
from the point of view of the symmetries, the action, and the equations of
motion. This limit can only be realized in a supersymmetric way provided we
impose by hand a set of geometric constraints, invariant under all the
symmetries of the non-relativistic theory, that define a so-called `self-dual'
Dilatation-invariant String Newton-Cartan geometry. The non-relativistic action
exhibits three emerging symmetries: one local scale symmetry and two local
conformal supersymmetries. Due to these emerging symmetries the Poisson
equation for the Newton potential and two partner fermionic equations do not
follow from a variation of the non-relativistic action but, instead, are
obtained by a supersymmetry variation of the other equations of motion that do
follow from a variation of the non-relativistic action. We shortly discuss the
inclusion of the Yang-Mills sector that would lead to a non-relativistic
heterotic supergravity action.Comment: 40 pages, minor change
Current clinician perspective on non-vitamin K antagonist oral anticoagulant use in challenging clinical cases.
OBJECTIVE: The evolution of non-vitamin K antagonist anticoagulants (NOACs) has changed the horizon of stroke prevention in atrial fibrillation (SPAF). All 4 NOACs have been tested against dose-adjusted warfarin in well-designed, pivotal, phase III, randomized, controlled trials (RCTs) and were approved by regulatory authorities for an SPAF indication. However, as traditional RCTs, these trials have important weaknesses, largely related to their complex structure and patient participation, which was limited by strict inclusion and extensive exclusion criteria. In the real world, however, clinicians are often faced with complex, multimorbid patients who are underrepresented in these RCTs. This article is based on a meeting report authored by 12 scientists studying atrial fibrillation (AF) in diverse ways who discussed the management of challenging AF cases that are underrepresented in pivotal NOAC trials. METHODS: An advisory board panel was convened to confer on management strategies for challenging AF cases. The article is derived from a summary of case presentations and the collaborative discussions at the meeting. CONCLUSION: This expert consensus of cardiologists aimed to define management strategies for challenging cases with patients who underrepresented in pivotal trials using case examples from their routine practice. Although strong evidence is lacking, exploratory subgroup analysis of phase III pivotal trials partially informs the management of these patients. Clinical trials with higher external validity are needed to clarify areas of uncertainty. The lack of clear evidence about complex AF cases has pushed clinicians to manage patients based on clinical experience, including rare situations of off-label prescriptions
A search on the Nikiforov-Uvarov formalism
An alternative treatment is proposed for the calculations carried out within
the frame of Nikiforov-Uvarov method, which removes a drawback in the original
theory and by pass some difficulties in solving the Schrodinger equation. The
present procedure is illustrated with the example of orthogonal polynomials.
The relativistic extension of the formalism is discussed.Comment: 10 page
An integrated assessment of water quality in an arsenic containing aquifer: Milestones from hydrogeology to public health
5th International Perspective on Water Resources & the Environment Conference (IPWE 2012), MoroccoA multi-disciplinary research is being conducted in Simav Plain, Turkey where an
arsenic containing aquifer is at the center of attention. The study is not only aimed to
understand the sources and mechanisms of the presence of high arsenic levels in
groundwater but also to determine the associated consequences with regards to
human health. The high arsenic levels in most groundwater (N=33, avg. 162 ppb),
surface water (N=9, avg. 76.6 ppb) and geothermal water (N=3, avg. 406 ppb)
samples are strongly related to high occurrences of arsenic in rocks and soils of the
plain, which range between 7.1 and 833.9 ppm with an average of 49 ppm. These
values correspond to several orders of magnitude higher than international standards
and world averages in water and soil, respectively. With this motivation, this
research also focuses on human health in the study area associated with exposure to
these high arsenic levels via numerous pathways. Consequently, more than 1000
individuals were personally surveyed by public health specialists to determine an
inventory of diseases in the area. Furthermore, a verbal autopsy study was also
conducted with relatives of the deceased, which were further verified with hospital
records, to understand the underlying death cause. As a result, certain cancer rates
were found to exceed national averages and the results statistically demonstrated a
potential link with high arsenic levels mainly through oral exposure
Exponential Type Complex and non-Hermitian Potentials in PT-Symmetric Quantum Mechanics
Using the NU method [A.F.Nikiforov, V.B.Uvarov, Special Functions of
Mathematical Physics, Birkhauser,Basel,1988], we investigated the real
eigenvalues of the complex and/or - symmetric, non-Hermitian and the
exponential type systems, such as Poschl-Teller and Morse potentials.Comment: 14 pages, Late
- …