AN EXAMINATION OF SPORTS SUCCESS IN SCHOOLS AND AMATEUR SPORTS CLUBS IN AFYONKARAHISAR, TURKEY

The purpose of this research is to examine the success of the sport in schools and amateur sports clubs in Afyonkarahisar. This study aims to determine the rankings of students' achievements in amateur sports clubs and school sports, considering various variables. A total of 80 amateur sports clubs in Afyonkarahisar city center and 184 school teams participating in sports competitions were examined, and their success statuses were ranked. This research used a descriptive research model that aims to describe existing facts as they are. A descriptive research model is an approach that aims to describe a situation as it currently exists (Karasar, 2012). For the study, statistics from the Ministry of Youth and Sports (GSİM) and the Ministry of National Education (MEM) for the years 2015-2020 were collected. This included data on the number of amateur sports clubs, the number of athletes, sports branches, the number of athletes going to national teams, student numbers from the Ministry of National Education, facility numbers, and success statistics. Descriptive statistics of the data were collected, and a descriptive data analysis was performed. The normality of distribution was checked in data analysis, and a normality test was conducted. Descriptive statistics (frequency distribution) were used in the statistical analysis of the obtained data. At the end of the research, reasons for the lower-than-expected sports success in schools and amateur sports clubs in Afyonkarahisar were identified, and descriptive findings on solutions were provided.  Article visualizations

Evaluation of e-complaints about food and beverage enterprises in tripadvisor: The case of Cappadocia region

Artan turizm hareketliliği ile birlikte günümüz turistleri daha fazla yeri görme ve deneyimleme arzusu içerisindedir. Turistler bu arzularını giderebilmek adına sıklıkla internet üzerinden araştırmalar yaparak, yeni yerleri keşfetmektedirler. Turistler yeni yerleri araştırırken, sıklıkla turizm işletmeleri hakkında yorumları barındıran Tripadvisor isimli web sitesini kullanmaktadırlar. Bu site, daha önce turizm işletmelerini deneyimleyen kişilere yorum ve değerlendirme yapma olanağı sunmaktadır. Turistler Triadvisor’a olumlu görüşlerin yanı sıra şikayet içerikli yorumlar da yapabilmektedirler. Bu şikayet içerikli yorumlar, turistlerin tercihlerinde etkin olabilmektedir. Bu çalışmanın amacı; Kapadokya bölgesinde yer alan birinci sınıf yiyecek ve içecek işletmeleri hakkında Tripadvisor üzerinden yapılan şikayet içerikli yorumları incelemek, sınıflandırmak ve şikayetlerle ilgili uygulayıcılara öneriler sunmaktır. Bu amaçla; Kapadokya bölgesinde yer alan yedi birinci sınıf yiyecek ve içecek işletmesi hakkında yapılan, 119 şikayet içerikli yorum incelenmiş, sınıflandırılmış ve öneriler sunulmuştur. Sınıflandırma işlemi nitel veri analizi programı ile kodlama yapılarak yapılmıştır. Yapılan kodlama işlemi sonucunda altı ana tema ve yirmi üç alt tema elde edilmiştir. Çalışmanın sonuç kısmında ise; şikayet içerikli yorumların yoğunlaştığı konular üzerinde değerlendirmeler yapılarak, öneriler geliştirilmiştir.With the increasing tourism mobility, today's tourists desire to see and experience more places. Tourists often want to explore new places by searching on the internet in order to fulfill their desires. Tourists about new places often use the Tripadvisor website, which hosts reviews of tourism businesses. This site offers the opportunity to comment and evaluate people who have previously experienced tourism businesses. In this way, other tourists can decide faster based on real experiences. Tourists can write positive comments to Triadvisor as well as complainant comments. These complaints can be effective in the preferences of tourists. The aim of this study; examine and categorize the complaints made by Tripadvisor about the first class food and beverage establishments in Cappadocia region which millions of tourists visited during the year. For this purpose, 119 complaints about seven first class food and beverage establishments in Cappadocia region were reviewed and classified. Classification process was done by coding with qualitative data analysis program. As a result of the coding process, six main themes and twenty-three sub-themes were obtained. In the conclusion part of the study; suggestions were developed by making evaluations on the subjects where complaints were concentrated

Could the increase in oxidative stress be the reason for the increased polyamine levels in diabetic obese and non-diabetic obese patients?

Putresin, spermine, and spermidine are important polyamines found in all living organisms. In this study, as a first in the literature, we aimed to investigate polyamines levels and their relationship with oxidative stress in obese adults. The study was carried out with 85 obese patients and 29 healthy controls. Glucose, HbA1c, urea, uric acid, CRP, Total antioxidant status and Total oxidant status putrescine, spermine and spermidine levels were analysed. The study found putrescine and spermidine levels in obesity (0.25 ±0.13) (2.29 ±0.79) were found to be significantly lower, respectively, than the control group (0.38± 0.08) (1.80 ± 0.68) (p<0.05). It was observed that both OSI and TOS values in the diabetic obese group were statistically higher than both the control group and the non-diabetic obese group. As a result; although polyamine levels are low in obesity, increased oxidative stress in the diabetic obese group caused an increase in polyamine levels

Is There Any Correlation Between De Ritis Ratio and Prostate Cancer in Males Who Underwent Transrectal Prostate Biopsy?

Objective:This study aims to evaluate the diagnostic value of the De Ritis ratio (DRR) in predicting prostate cancer (PCa) and clinically significant prostate cancer (csPCa) in biopsy-naive patients with suspected PCa.Method:We retrospectively reviewed medical records of 282 male patients who underwent transrectal ultrasound-guided prostate needle biopsy (PNB) between January 2015 and July 2019. Demographic and clinical characteristics of the patients including digital rectal examination findings, preoperative prostate-specific antigene (PSA), aspartate aminotransferase levels, alanine aminotransferase levels, prostate volume, comorbidities and pathological findings of the PNB specimens were noted in detail for each patient. The study cohort was divided into two groups according to the histopathological results of PNB specimens (group 1: patients with benign histopathology, group 2: patients with PCa). The receiver operating characteristic (ROC) curve analysis was conducted to evaluate the diagnostic performance of PSA, PSA density and DRR in predicting PCa.Results:The median age of the participants was 64 (59-69) years. While 71.6% (n=202) of the participants were in group 1, 28.4% (n=80) of them were in group 2. The median DRR value of group 1 was 1.08 (range: 0.89-1.32), and the median DRR value of group 2 was determined as 1.19 (range: 0.95-1.56), and the median DRR value of group 2 was found to be statistically significantly higher than that of group 1 (p=0.013). Statistically significant but a weak positive correlation was observed between PCa in PNB specimens and DRR (r=0.149, p=0.012), while there was no statistically significant correlation between csPCa in PNB specimens and DRR (r=0.002, p=0.983). The ROC curve analysis showed that the cut-off value of DRR for the presence of PCa in PNB specimens was 1.125 and the area under curve was 0.595 (95% confidence interval=0.518-0.672, p=0.013) for the presence of PCa in PNB specimens.Conclusion:This study suggests that DRR had restricted diagnostic importance in predicting PCa in biopsy-naive patients who underwent transrectal PNB

The Bibliometric Analysis of the Studies Presented at the Turkish National Otorhinolaryngology Congresses in the Period 2009-2018

Objective: The aim of this study was to quantitatively and qualitatively analyze the abstracts presented at Turkish National Otorhinolaryngology Congresses in the years from 2009 to 2018.Methods: Abstracts were defined and grouped according to their field of study, design, level of evidence, number of authors, the main institution in which they were held, and whether they were uni- or multi-centric. Frequency and percentage tables were prepared.Results: In total, 5,463 studies, of which 1,431 (26.2%) were oral presentations and 4,032 (73.8%) were poster presentations were reviewed. The highest number of studies was in the field of otology and in the form of oral presentations (32%), and in the field of head and neck surgery in the form of poster presentations (37%). Fifty-seven percent of all studies were conducted in university hospitals, and 34% in Training and Research Hospitals. Eighty-three percent of oral presentations and 99% of poster presentations were clinical studies. The rate of experimental animal studies was 16% in oral presentations. The most commonly used design of orally presented clinical studies was descriptive (31%), whereas prospective randomized controlled design was the least common (3%). No study with a level 1 of evidence was found. The rate of oral papers presented with evidence levels 2, 3, 4, and 5 among all oral presentations were 22%, 13%, 11%, and 54%, respectively.Conclusion: The findings indicated that the abstracts were satisfactory in quantity, but overall scientific quality was not sufficient. The data obtained may serve as a basis for future studies, and follow-up studies may guide individuals and institutions that steer the Turkish ENT community

Comprehensiveness of online sources for patient education on otosclerosis

PurposeThis study aimed to assess the readability indices of websites including educational materials on otosclerosis.MethodsWe performed a Google search on 19 April 2023 using the term “otosclerosis.” The first 50 hits were collected and analyzed. The websites were categorized into two groups: websites for health professionals and general websites for patients. Readability indices were calculated using the website https://www.webfx.com/tools/read-able/.ResultsA total of 33 websites were eligible and analyzed (20 health professional-oriented and 13 patient-oriented websites). When patient-oriented websites and health professional-oriented websites were individually analyzed, mean Flesch Reading Ease scores were found to be 52.16 ± 14.34 and 46.62 ± 10.07, respectively. There was no significant difference between the two groups upon statistical analysis.ConclusionCurrent patient educational material available online related to otosclerosis is written beyond the recommended sixth-grade reading level. The quality of good websites is worthless to the patients if they cannot comprehend the text

Comparison of Voice Quality and Cost Effectiveness of Endoscopic Cordectomy Using Microdissection Electrodes with Laser Cordectomy and Radiotherapy

Objective: To compare the acoustic parameters and the cost effectiveness achieved after endoscopic cordectomy using radiofrequency microdissection electrodes (ECRM) with those of transoral laser cordectomy and radiotherapy.Methods: The study included 81 disease-free patients previously treated for early larynx carcinoma (30 with ECRM, 27 with transoral laser cordectomy, 24 with primary radiotherapy). Post-treatment voice analysis was performed in all patients. Additionally, the cost effectiveness of all treatment procedures was calculated.Results: The GRBAS (G: Grade, R: Roughness, B: Breathiness, A: Asthenia, and S: Strain) scale showed a significant difference between the groups (p0.05 for all). Percent jitter, percent shimmer and fundamental frequency (F0) were significantly different in the radiotherapy group than the ECRM and the transoral laser cordectomy groups (p0.05). The mean cost of the ECRM technique was statistically lower than the other treatment techniques (p<0.05). Moreover, the length of hospital stay after ECRM was statistically significantly shorter than was after laser cordectomy (p<0.05).Conclusion: Objective and perceptive voice analysis after ECRM showed comparable results with transoral laser cordectomy, but poorer results than radiotherapy. Cost effectiveness of ECRM was found to be better than the other two treatment techniques

Yakın gerçek zaman işlemli, fiberde tümleşik atmalı terahertz spektrometre

TÜBİTAK TBAG01.08.2015TUBİTAK tarafından desteklenen 111T748 nolu, “Yakın Gerçek Zaman İşlemli, Fiberde Tümleşik Atmalı Terahertz Spektrometre” başlıklı araştırma projesinden elde edilen sonuçlar açıklanmaktadır. Çalışmalar zamana dayalı terahertz spektrometre ölçüm tekniğin anlık olarak gerçekleştirilmesine ve bu yöntemlerin pompa/sonda ölçümlerinde kullanılması için geliştirilmesine odaklanmıştır. Proje kapsamında tekrarlama frekansını çok hızlı değiştirebilen, üç çıkış kolu olan, 1030nm merkez dalga boyunda çalışan özgün tasarıma sahip Yb: katkılı kip-kilitli fiber lazer sistemi geliştirilmiştir. Üç çıkış kolundan, kısa atım kolu (<150fs) Terahertz (THz) algılanmasında, uzun atım kolu (<250fs) THz üretiminde ve pompa kolu (<1ps) pompa/THz sonda deneylerinde kullanılması için geliştirilmiştir. Geliştirilen bu özgün lazer sistemi ile THz atım ölçümlerin ölçüm hızında neredeyse anlık olarak gerçekleştirilmesi için lazerin tekrarlama frekansın hızlı değişimi sağlanmıştır (~10Hz). Bu amaçlara ulaşmak için sistem içinde terahertz atımlarını üretmek, iletmek ve belirlemek için kullanılan birimlerin her biri optimize edilmiştir. Aynı zamanda lazerin pompa kolundaki çıkış gücünü yükselterek sistemin pompa/THz sonda deneylerinde anlık ölçüm tekniğini kullanarak uygulanması amaçlanmıştır. Böylelikle bu yeni ölçüm tekniği ile yurtdışındaki araştırma laboratuvarlarında geleneksel kullanılan pompa/sonda yöntemlerine hız kazandırarak farklı fiziksel etkenlerin tespitine katkı sağlayabileceğiz.Genelde zamana dayalı terahertz ölçüme dayalı spektroskopi yöntemi, pompa/THz prob (sonda) veya benzeri dinamik ölçüm deneyleri için sistem temelinde güçlendirilmiş atmalı lazer sistemleri kullanılmakta ve THz atım şeklinin ölçüm temelinde interferometrik teknikler kullanıldığından spektrum verilerinin kaydedilmesi onlarca dakika sürebilmektedir. Bu sistemler ile yakın gerçek zaman işlemeli spektroskopi ölçümlerin ve anlık dinamik olayları gözlemeyebilmek için hızlı pompa/THz prob (sonda) ölçüm kabiliyetinin kazanılması, madde karakterizasyonu yapan birçok araştırma grubu için önemli bir destek sağlayacaktır. Örneğin bazı biyolojik ve kimyasal reaksiyonlar saniyeler mertebesinde gerçekleştiğinden bu etkileşimlerin nasıl geliştiği bu tip bir anlık THz spektroskopi yöntemi sonucu daha iyi anlaşılabilenecektir. Aynı zamanda uygun pompalama lazerin fotouyarı sonrası, prob (sonda) görevi yapan THz darbelerin düşük foton enerjisi sayesinde birçok farklı malzeme türleri karakterize edilebilecektir. Bu tip bir ölçüm yeneteğini geliştirmek için proje çalışmasında tekrarlama oranı hızla ayarlanabilen, yükseltilmiş iterbiyum (Yb) katkılı kip-kilitli fiber lazer sistemini geliştirdik ve bu sistemden üç farklı çıkış sağlayarak hem THz atım üretimi, hem belirlenmesi hemde pompa/THz prob (sonda) deneyleri yapabilen bir sistem geliştirdik. Lazerin üç çıkış kolundaki ışın parametrelerini optimize ederek sistem ile yakın gerçek zaman işlemli, dinamik ölçüm yapabilen atmalı terahertz spektrometre ölçümlerin yapılabildiğini gösterdik. Kip-kilitli lazerlerin tekrarlama oranları lazer kavitesinin fiziksel olarak uzunluğunun değişmesi ile ayarlanabilmesine rağmen farklı kavite uzunluklarında aynı kararlılığı (çıkış gücü, atım süresi, tayf genişliği) gösterememektedir. Proje kapmsamında yaptığımız çalışmalarda farklı kavite uzunluklarında kararlı çalışan Yb: katkılı kip-kilitli fiber lazer geliştirerek lazer tekrarlama frekansını çok hızlı bir şekilde değiştirebileceğimizi gösterdik. Lazer çıkışındaki güç ve darbe sürelerini uygun pompalama diyotları ve özel ızgara optik bileşenleri kullanarak THz atım üretimi ve belrilenmesini lazer kavite uzunluğunu değiştirerek optik örnekleme metodu ile yapılabileceğini gösterdik. Bu sayede THz atım şeklini daha hızlı belireyebileceğimiz için çok kısa sürelerde gerçekleşen kimyasal/fiziksel olayları aydınlatabilecek yeni bir ölçüm tekniğin temelini oluşturduk. Elde edilen hızlı tarama süreleri ve Yb: katkılı lazerlerin Er: katkılı lazerlere göre daha yüksek verimde çalışması sayesinde bu tip sistemler pompa/THz prob (sonda) gibi dinamik ölçüm kabiliyetine dayanan birçok deney için önemli bir yenilik kazandıracaktır.Dynamical measurement techniques such as terahertz time-domain spectroscopy, pump/THz probe spectroscopy or similar techniques typically are driven by amplified pulsed laser systems and all utilize interferometric techniques to measure and record the THz profile which results in measurement times that can last tens of minutes. Rapid pump/THz probe measurement techniques will aid in observing instantaneous phenomena or perform near real-time spectroscopy benefiting many research groups which work in the field of material characterization. For example, since some biological and chemical reactions occur in a matter of seconds the interaction of these phenomena with THz waves can be better understood using near-real time measurement techniques. At the same time, after photo excitation at the appropriate pump wavelength the low photon energy THz probe will allow the characterization of a variety of materials. In this research project, to have access to such measurements, we have developed a THz spectrometer driven by an ultrafast amplified Ytterbium (Yb) doped fiber laser whose repetition rate can be tuned rapidly which allows for such dynamical measurements. The system we developed has three outputs which are used for THz pulse generation, THz pulse detection as well as pump/THz probe experiments. By optimizing the optical beam parameters in all three arms we showed that the system can be used for near- real time, pulsed terahertz measurements for dynamical systems. Even though one can tune the repletion rate of a mode-locked laser by changing the cavity length the output beam stability will typically not remain stable (output beam power, pulse duration, and spectral width). Towards this goal, we developed a mode-locked amplified Yb: doped fiber laser system which showed the same output beam parameters despite rapid changes in its repetition rate or cavity length. By using adequately driven pump diodes and appropriate gratings we were able to control and stabilize the power output as well as the pulse duration allowing the use of optical sampling by cavity tuning methods to be utilized in the generation and detection of THz pulses. By developing the method of rapid scanning of the repetition frequency and using highly efficient Yb: doped fiber lasers when compared to Er: doped ones we were able to show that this system can be utilized in many experiments which show dynamical behavior such as pump/THz probe spectroscopy

Laboratuvardan Kliniğe Transplantasyon Pratiği

Transplantasyon; Temel Tıbbi Bilimler, Moleküler Tıp, Genetik ve İmmünolojiden klinik uygulamalardan destek alan multidisipliner bir tıp dalıdır. Temel bilimlerdeki başarılı çalışmaların kliniğe uygulanması, klinikte karşılaşılan sorunların da, oluşturulan deneysel hayvan modellerinde irdelenmesi, elde edilen bilgilerin klinik uygulamalara aktarılması; diğer deyişle tecrübelerin “Translational” özellikli olması günümüz transplantasyon çalışmalarında bir gerekliliktir. İmmün sistemin bileşenlerinin ve reaksiyonlarının iyi bilinmesi, hücreler arası ilişkilerde greftin reddi ya da kabul edilmesinin şartlarını doğru anlamak ve uygun laboratuvar yöntemleri ile klinik durumun aydınlatılması transplantasyonda stratejik önemdedir. Bu nedenle, klinik transplantasyon çalışmaları yapanlar temel bilimler bilgileri ile de donanımlı olmalıdırlar. Multidisipliner bir dal olma bilinci ile yapılan klinik transplantasyon çalışmalarında başarı yakalanmaktadır. Laboratuvardan Kliniğe Transplantasyon kitabımızda tüm yönleri ile transplantasyonun organizmaya etkileri ve bunların klinik sonuçlarını, çalışmalarımızın ışığında sunmayı ve tartışmayı hedefledik. Editör: Prof.Dr. Mesut İzzet TİTİZ Yardımcı Editör: Doç.Dr. Pınar AT