WOMEN’S BREAST CANCER CONSCIOUSNESS AND SPORT - EXAMPLE OF BURDUR, TURKEY

With the study, titled “Women’s Breast Cancer Consciousness and Sport Burdur Example” aimed at the awareness and practice of breast cancer in women at Burdur city center. In our study; descriptive screening and structured interview technique were applied. At the end of the research; Regardless of the education level of women, it is determined that awareness of breast cancer is high with the information and guidance received from both health institutions and the media and the people who have previously faced breast cancer, and it is determined that early diagnosis can save life and can beat breast cancer with the least damage. However, this training should be provided by Family Education Centers and Provincial Health Directorates to all women who are aware of the necessity of regular and good eating habits. When we compare the results of our study with other related researches, it was determined that early diagnosis in breast cancer saved lives.  Article visualizations

catena-Poly[[[bis­(4-ethyl­benzoato-κ2 O,O′)lead(II)]-μ-nicotinamide-κ2 N 1:O] monohydrate]

In the crystal structure of the polymeric title compound, {[Pb(C9H9O2)2(C6H6N2O)]·H2O}n, the six-coordinate PbII ion is chelated by two 4-ethyl­benzoate (PEB) anions and is bridged by two nicotinamide (NA) ligands, forming a polymeric chain running along the b axis. The carboxyl­ate groups of the PEB ions are twisted away from the attached benzene rings by 4.0 (6) and 13.3 (5)°. The two benzene rings of the PEB ions bonded to the same metal ion are oriented at a dihedral angle of 87.4 (3)°. In the polymeric chain, the NA ligand is linked to one of the carboxyl­ate groups via N—H⋯O hydrogen bonding. In the crystal, adjacent polymeric chains inter­act via N—H⋯O and weak C—H⋯O hydrogen bonds; and the lattice water mol­ecule links with the polymeric chains via N—H⋯O and O—H⋯O hydrogen bonding. π–π stacking between the benzene and the pyridine rings [centroid–centroid distance = 3.805 (5) Å] and weak C—H⋯π inter­actions are also observed in the crystal structure

Acute massive myelofibrosis with acutelymphoblastic leukemia

Acute myelofibrosis is characterized by pancytopenia of sudden onset, megakaryocytic hyperplasia, extensive bone marrow fibrosis, and the absence of organomegaly. Acute myelofibrosis in patients with acute lymphoblastic leukemia is extremely rare. We report a 4-year-old boy who was diagnosed as having acute massive myelofibrosis and acute lymphoblastic leukemia. Performing bone marrow aspiration in this patient was difficult (a “dry tap”), and the diagnosis was established by means of a bone marrow biopsy and immunohistopathologic analysis. The prognostic significance of acute myelofibrosis in patients with acute lymphoblastic leukemia is not clear

Procedural sedation protocols with or without ketamine in pediatric gastrointestinal endoscopy: A retrospective cohort study

Objective: A considerable difference exists in pediatric endoscopy sedation practices with the optimal sedation protocol for gastrointestinal (GI) endoscopy a subject of controversy and to investigate the safety and efficacy of sedation protocols with or without ketamine in procedural sedation for pediatric GI endoscopy. Materials and Methods: A total of 78 pediatric patients who received sedation anesthesia for GI endoscopy were included in this retrospective study. Anesthesia parameters include duration time, doses of anesthetic agents, Ramsay sedation score, respiratory and hemodynamic parameters, recovery time, modified Aldrete recovery scores, and side effects. Study parameters were evaluated with respect to ketamine dose (no ketamine group (NKG), low-dose ketamine group (LDKG, ≤0.75 mg/kg), and high-dose ketamine group (HDKG, ≥1 mg/kg). Results: The upper GI endoscopy rate (58.12% vs. 90.0%, p=0.001) was significantly lower in LDKG versus HDKG. No significant changes were observed in blood pressure levels, oxygen saturation, or heart rate compared to baseline levels. No significant difference was noted between study groups in terms of recovery time, modified Aldrete recovery scores, and nausea/vomiting. Final Ramsay sedation scores were significantly higher in NKG (p<0.05) and LDKG (p<0.01) than in HDKG. Conclusion: Our findings indicate a favorable safety and efficacy profile for ketamine as a useful adjunct to procedural sedation for pediatric GI endoscopy, enabling better quality of sedation with a low risk of cardiorespiratory suppression, or serious complications

Structural, electronic and phononic properties of PtSe2: From monolayer to bulk

The layer dependent structural, electronic and vibrational properties of the 1T phase of two dimensional (2D) platinum diselenide are investigated by means of state-of-the-art first-principles calculations. The main findings of the study are: (i) monolayer platinum diselenide has a dynamically stable 2D octahedral structure with 1.66 eV indirect band gap, (ii) the semiconducting nature of 1T-PtSe2 monolayers remains unaffected even at high biaxial strains, (iii) top-to-top (AA) arrangement is found to be energetically the most favorable stacking of 1T-PtSe2 layers, (iv) the lattice constant (layer-layer distance) increases (decreases) with increasing number of layers, (v) while monolayer and bilayer 1T-PtSe2 are indirect semiconductors, bulk and few-layered 1T-PtSe2 are metals, (vi) Raman intensity and peak positions of the A1g and Eg modes are found to be highly dependent on the layer thickness of the material, hence; the number of layers of the material can be determined via Raman measurements.TUBITAK under the project number 117F09

2-Ethyl-6,6-ethyl­enedisulfanediyl-7-methoxy­methyl-1,2,3,4,5,6-hexa­hydro-1,5-methano­azocino[4,3-b]indol-3-one

The title compound, C20H24N2O2S2, consists of a tetra­cyclic ring system containing an azocino skeleton with ethyl, dithiol­ane and methoxy­methyl groups as substituents. The benzene and five-membered rings are nearly coplanar, with a dihedral angle of 2.78 (11)°. The dithiol­ane ring adopts an envelope conformation. In the crystal structure, inter­molecular C—H⋯O hydrogen bonds link the mol­ecules into chains nearly parallel to the c axis. Two C—H⋯π inter­actions are also present

Birinci Sınıflarda İstenmeyen Davranışların Yaş Farklılıklarına Göre Dağılımı ve Bu Davranışlara Yönelik Öğretmen Tepkileri

Türk Milli Eğitim Bakanlığı 2012-2013 eğitim-öğretim yılı ile birlikte birinci sınıfta öğrencilerin yaş farklılıklarını arttıran bir uygulama başlatmıştır. Bu karar sonucunda birinci sınıf öğrencileri arasında iki yaşa varan farklılıklar oluşmuştur. Kronolojik olarak gözlenen bu farklılığın zekâ yaşı dikkate alındığında daha geniş olması beklenmektedir. Araştırma geniş yaş farklılıklarının olduğu birinci sınıflarda gözlenen istenmeyen öğrenci davranışlarının yaş gruplarına göre dağılımını ve öğretmenlerin bu davranışlara yönelik tepkilerini belirlemeyi amaçlamaktadır. Araştırmada nitel araştırma yöntemlerinden durum çalışması deseni kullanılmıştır. Örneklem seçiminde amaçlı örneklem yönteminden aşırı (uç) örnekleme yöntemi seçilmiştir. Araştırma verileri sosyo-ekonomik düzeyi yüksek bir okuldan yapılandırılmış gözlem ve yarı-yapılandırılmış görüşme tekniği ile elde edilmiş, analiz tekniği olarak içerik analizi kullanılmıştır. Araştırma sürecinde birinci sınıf öğrencilerinin istenmeyen davranışlarının yaş gruplarına göre farklılık gösterdiği ancak öğretmenlerin yaş gruplarını dikkate almadan benzer tepkiler gösterdiği ve küçük yaş gruplarına büyük yaş gruplarından daha fazla tepki gösterdiği yönünde bulgulara rastlanmaktadır.

Regio- and stereo-chemical ring-opening reactions of the 2,3-epoxy alcohol derivative with nucleophiles: Explanation of the structures and C-2 selectivity supported by theoretical computations

The ring-opening reactions of (1aS,2S,6bR)-5-ethyl-2-hydroxyhexahydro-4H-oxireno[2,3-e]isoindole-4,6(5H)-dione were investigated under very mild and nonchelated conditions. C-2 selective ring-opening products were obtained with nucleophilic additions such as Cl-, Br- and N-3(-). The exact configuration of (3aS,4R,5R,6S,7aS)-5-chloro-2-ethyl-4,6-dihydroxyhexahydro-1H-isoindole-1,3(2H)-dione was determined by X-Ray diffraction analysis which was obtained from the reaction of epoxy alcohol with HCl . On the other hand, theoretical computations were carried out to explain the regioselectivity in the ring opening reaction of epoxy alcohols. The results showed that the ring-opening reaction of both epoxy alcohols proceeds in a kinetically controlled manner and regioselectivity occurs depending on the transition state. (c) 2022 Published by Elsevier B.V

Helicobacter pylori infection in amniotic fluid may cause hyperemesis gravidarum

Objectives: Limited data are available from recent trials involving pregnant women to guide Helicobacter pylori infection diagnosis. There are no data about the presence of H. pylori in the amniotic fluid as well. Furthermore, the relation between amniotic fluid H. pylori and hyperemesis gravidarum (HG) has not been characterized yet. Materials and Methods: This is a prospective study conducted after obtaining approval from the Ethics Committee. Pregnant women undergoing amniocentesis were enrolled in the study. The stool antigen test assessed the presence of H. pylori in amniotic fluid. A perinatologist independently performed an amniocentesis. The obtained amniotic liquid was sent to the laboratory to evaluate H. pylori infection by stool H. pylori antigen assay. We determined the rate of H. pylori in amniotic fluid and assessed relations between H. pylori infection and pregnancy outcome, including HG. Results: Between May and September 2017, we enrolled 48 pregnant women who underwent amniocentesis to detect possible fetal malformations. Patients were divided into two groups regarding the HG status. There were significant differences between the groups in terms of H. pylori infection presence. Among them, 28 (58.3%) were found to have a positive H. pylori test in their amniotic fluid. The rate of HG was significantly higher (71.4%) in patients who tested positive for H. pylori in amniocentesis than the H. pylori-negative group (20%), (p<0.001). Conclusions: The study’s main new finding is that presence of H. pylori in the amniotic fluid is possible. Our data suggest that H. pylori-infected amniotic fluid is associated with the experience of past HG. The current study may have important implications for HG detection and help identify patients who would benefit from future preventive strategies. © 2020 Global Research Online. All rights reserved

An Instructional Model for Social Design Education: A Design Project for Stray Animals Including Production-Based Learning Approach

Social design education has become a significant part of industrial design education, thus new methodologies are required and being developed. One of these societal problems is animal welfare and human interaction with stray animals that is not a common topic amongst previous studies. This study presents a toolkit for social design teaching, combining social design thinking and product development processes to generate and realise design solutions for stray animals with a production-based learning approach. The toolkit consisting of nine phases under two processes was implemented into the second-year ‘Product Design II’ 7-week studio project at Gazi University. A total of 35 sophomores taking the course offered during the second semester of the 2017/2018 academic year, participated in housing and feeding stations for a stray animals’ design project. To analyse the appropriateness of the toolkit, the submissions and process of the project were observed and evaluated by instructors and post-project questionnaires were employed to both instructors and students. The results revealed that this toolkit for social design education combining design thinking and product development processes improved industrial design students’ competencies and learning outcomes