Evaluation of tear function tests and corneal thickness in patients with meibomian gland dysfunction

Objectives: To investigate whether central corneal thickness (CCT) and tear function test differ from healthycontrols in the ones suffering meibomian gland dysfunction (MGD).Methods: This prospective study was carried out with 99 individuals in total (50 patients MGD, 49 healthyindividuals). Schirmer-1, tear break-up time (TBUT), the Ocular Surface Disease Index (OSDI) questionnaireand CCT measurmentwas administered to all patients.Results: The average Schirmer 1 measurements were 16.6 ± 3.3 mm for right eyes, 16.4 ± 3.6 mm for lefteyes in the MGD group and 17.1 ± 3.7 mm for right eyes, 17.0 ± 4.4 mm for left eyes in the control group. Themean TBUT values were 10.1 ± 3.6 seconds for right eyes, 10.2 ± 3.4 seconds for left eyes in the MGD groupand 14.7±3.7 seconds for right eyes, 15.8 ± 4.1 seconds for left eyes in the control group (p = 0.001). Themean OSDI score values were 40.3 ± 23.7 in the MGD group and 19.4 ± 8.7 in the control group (p = 0.001).The average CCT in the MGD group was 539.4 ± 30.0 µm and 539.7 ± 33.0 µm (right and left, respectively).The average CCT in the control group was 551.6 ± 32.8 µm and 550.7 ± 32.2 µm (right and left, respectively).The mean CCT measurements in the MGD group were not statistically significant compared to the healthycontrol group (p = 0.059, and p = 0.097, right and left, respectively).Conclusions: The Schirmer test and CCT measurements are not significantly different in patients with MGDcompared to healthy control subject

Treatment of a case with giant eyelid syringomas

He had a history of multiple asymptomatic flesh-colored papules, which hadslowly increased in number and coalesced into plaques, on both upper andlower eyelids. Some of the plaques were giant and mostly coalescent in nature.We excised surgically the giant plaques which were approximately 1.5-2 cm indiameter symmetrically from upper and lower eylids and the remaining plaqueswere left to be treated with cauterization. Histopathological examination revealedsyringoma. Both of the eyelids were observed to have a cosmetically adequateappearence after the surgical intervention

Keratoconus Could Be Associated With Psoriasis: Novel Findings From a Comparative Study

Karagun, Ebru/0000-0002-5032-7429WOS: 000509673000013PubMed: 31574049Purpose: To explore the relationship between keratoconus (KC) and psoriasis. Methods: One hundred ten eyes of 55 patients with psoriasis (study group, SG) and 110 eyes of age-sex-matched 55 healthy volunteers (control group, CG) were included in the study. All cases underwent a detailed dermatological and ophthalmological examination including corneal topography. Moreover, Psoriasis Area and Severity Index (PAST) scoring of the patients was carried out in the SG. A thorough comparison of pachymetric, aberrometric, and topometric values between the groups was performed, and the results were interpreted. A chi(2) test, Mann-Whitney U test, and Pearson correlation test were used for statistical assessment. Results: Although the average Kmax (44.6 in the SG; 44.5 in the CG; P = 0.613) and Belin/Ambrnsio enhanced ectasia total deviation value (1.34 in SG; 1.20 in CG; P = 0.880) were similar between the groups, the mean index of vertical asymmetry value in the SG (0.14 mm) was significantly higher than that in the CG (0.11 mm) (P = 0.041). Moreover, 28 eyes from 16 patients with psoriasis were found to be associated with KC because 26 of those 28 eyes were KC suspects and 2 of them were definite KC. A positive correlation was found among topometric parameters, especially between duration of the disease and PASI score. A negative correlation was discovered between topometric parameters and the early beginning of psoriasis. Conclusions: Serious changes in topography maps may occur in psoriatic patients. The changes were found to be more evident in the presence of a higher PAST score and the early beginning and longer duration of the disease. The results hinted a potential relationship between psoriasis and KC

The effects of non-invasive mechanic ventilator modes on intraocular pressure in COPD patients with hypercapnic respiratory failure

WOS: 000503149800001PubMed: 31799789Background Chronic obstructive pulmonary disease (COPD) is not fully reversible disease that is characterized by progressive restricting airflow. Non-invasive mechanical ventilation (NIMV) treatment can be used in COPD patients who had type 2 respiratory failure. This study aimed to determine the effect of BPAP S/T and AVAPS modes on intraocular pressure (IOP), central corneal thickness (CCT) in 40 type 2 respiratory failure patients with COPD. Methods Forty patients with type 2 respiratory failure who were hospitalized between June and December 2018 with the diagnosis of COPD exacerbations were included to the study. Patients followed up without NIMV for 12 hours after the end of exacerbations treatments end. After IOP, visual acuity and CCT were measured in all patients at the same time (11.00 am), same NIMV treatment was applied to the patients for 4 hours (AVAPS-BPAP S/T). Then the measurements were repeated. The effects of these NIMV modes on IOP were evaluated. Results After NIMV treatment, it was observed that the mean IOP increased statistically significantly (13.3 vs 12.3 mm Hg; P = 0.001). After treatment with NIMV, there was a decrease for CCT close to statistical significance (P = 0.057) Conclusion As a result; increased IOP and thinning of CCT after NIMV treatment has been shown. The type of NIMV and the level of inspiratory pressure needed in hypercapnic respiratory failure seem to affect IOP and it should be cautiously used to increase IOP