RELATIONSHIP BETWEEN TOURISM AND REGIONAL DEVE-LOPMENT: A STUDY ON TRC1 REGION

Bir bölgede turizm destinasyonların çeşitliliği ve bu destinasyonların insanların hizmetine su-nulması ülkenin refah düzeyinin artmasında önem arz eden unsurlardandır. Yapılan bu araştırmanın amacı, turizmin bölgesel kalkın-maya olan etkisinin, Güneydoğu Anadolu Böl-gesinde yer alan TRC 1 bölgesi göz önüne alına-rak tespit edilmesi ve TRC1 bölgesinin sahip olduğu turistik arz doğrultusunda turistlerin yapmış oldukları konaklama istatistiklerini ortaya koymaktır. Çalışmanın ana kaynağını, Kültür ve Turizm Bakanlığı verileri oluşturmak-tadır. Güneydoğu Anadolu Bölgesi içerisinde bulunan Adıyaman, Gaziantep ve Kilis şehirle-rinin sahip olduğu turistik arz ve talep özellikleri değerlendirilmiştir. Araştırmanın sonucunda TRC 1 bölgesinde en fazla konaklama tesisi ve en yüksek oranda turizm talebinin Gaziantep şehrinde olduğu sonucu tespit edilmiştirIn a region, variety of tourism destinations and presentation of these dedications for public usage are essential factors to increase of natio-nal welfare. The aim of this research is to iden-tify the effect of tourism on regional develop-ment by regarding the TRC 1 region and to introduce the accommodation statistics of tou-rists according to touristic supply that TRC 1 region. Main resource of the study consists of Culture and Tourism Ministry data. The touris-tic supply and demand values of Adıyaman, Gaziantep and Kilis which are located in Sout-heast Anatolia Region were evaluated. At the end of research it is found that Gaziantep has the highest accommodation and tourism de-mand rate

Relationship Between Glycosylated Hemoglobin and Vitamin B12 Deficiency Anemia

OBJECTIVE: Previous studies showed that vitamin B12 deficiency anemia causes a false increase in glycosylated hemoglobin (HbA1c) and that HbA1c decreases with B12 treatment. However, no study has been conducted on how much an increase in hemoglobin (Hgb) level causes a decrease in HbA1c level after treatment. METHODS: The study included 37 patients who were not diagnosed with diabetes, did not use anti-diabetic drugs, were pre-diabetic according to HbA1c level, and were diagnosed with vitamin B12 deficiency anemia in the patient group and 40 healthy volunteers of similar age and gender characteristics in the control group. The patient group was given 1 mg/day of cyanocobalamin (vitamin B12) orally for 3 months. Patients’ Hgb, mean corpuscular volume, fasting plasma glucose, HbA1c, and vitamin B12 values were compared at the beginning and at the end of the 3(rd) month. RESULTS: In the patient group, it was determined that 0.94 mg/dL increase in Hgb after vitamin B12 treatment caused a 0.24 decrease in HbA1c (%). The initial HbA1c of the patient group was 6.01±0.20 and the 3(rd)-month HbA1c was 5.77±0.33; the initial and 3(rd)-month Hgb values were 11.31±0.28 and 12.26±0.33, respectively; the initial and 3(rd)-month vitamin B12 (ng/L) levels were 112.43±7.18 and 408.48±119.61, respectively; and there was a significant difference between the initial and 3(rd)-month values (p<0.001, p<0.001, p<0.001, respectively). Moreover, 35% of the patients in the patient group had no diagnosis of prediabetes according to the HbA1c level at the end of the 3(rd) month. CONCLUSION: Elimination of vitamin B12 deficiency anemia before making a diagnosis or treatment decision according to HbA1c level will prevent patients from misdiagnosis of diabetes and unnecessary treatment changes in diabetic patients

RESEARCH BURDEN OF INTERSTITIAL LUNG DISEASES IN TURKEY - RBILD

Introduction: The aim of our study is to investigate the etiological distribution of ILD in Turkey by stratifying the epidemiological characteristics of ILD cases, and the direct cost of initial diagnosis of the diag-nosed patients. Material-Method: The study was conducted as a multicenter, prospective, cross-sectional, clinical observation study. Patients over the age of 18 and who accepted to participate to the study were included and evaluated as considered to be ILD. The findings of diagnosis, examination and treatment carried out by the cent-ers in accordance with routine diagnostic procedures were recorded observationally. Results: In total,1070 patients were included in this study. 567 (53%) of the patients were male and 503 (47%) were female. The most frequently diagnosed disease was IPF (30.5%). Dyspnea (75.9%) was the highest incidence among the presenting symptoms. Physical examination found bibasilar inspiratory crackles in 56.2 % and radiological findings included reticular opacities and interlobular septal thickenings in 55.9 % of the cases. It was observed that clinical and radiological findings were used most frequently (74.9%) as a diagnostic tool. While the most common treatment approaches were the use of systemic steroids and antifibrotic drugs with a rate of 30.7% and 85.6%, respectively. The total median cost from the patient's admission to diagnosis was 540 Turkish Lira. Conclusion: We believe that our findings compared with data from other countries will be useful in showing the current situation of ILD in our country to discuss this problem and making plans for a solution