Evaluate the correlations of maternal systemic ınflammatory markers such as neutrophil to lymphocyte ratio and platelet to lymphocyte ratio with gestation age

Objective: In this study, we aim to study the correlation between the maternal systemic inflammatory markers such as neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) including complete blood count (CBC) variables with gestation age, at the labor of our patients.Materials and Methods: This retrospective study was performed with 1127 patients and their infants. We used the maternal CBC variables analyzed within the last day before active labor. We analyzed the statistical differences between the NLR, PLR, and other CBC variables in terms of gestational age.Results: There was no statistically significant difference between the gestational age with NLR and PLR values, (P = 0.414 and P = 0.341, respectively). When we compare the NLR and PLR values in normal spontaneous vaginal delivery (NSVD) group, no statistically significant difference was found (P = 0.250; P = 0.995, respectively). In correlation analyses, no statistically significant correlation was detected between NLR and PLR with a birth weight of the infant and gestational age (P = 0.132 and P = 0.344, respectively). A linear, negative, weak correlation, and statistically significant correlation was detected between white blood cell count (WBC) with the infant’s birth weight and gestational week (P < 0.01 and P = 0.024, respectively).Conclusions: Inflammation plays an important role especially at the beginning of the labor. In our study, we showed no correlation of the NLR and PLR with a gestational week or infant’s birth weight at labor. Also, in our research, the NLR and PLR values did not differ statistically among the four groups in terms of the gestational age of delivery with the highest values in the preterm birth (<37 weeks) groups (P = 0.414, P = 0.341, retrospectively). Key words: Gestation week; inflammation; neutrophil to lymphocyte ratio; platelet to lymphocyte ratio

Vitamin D levels in pregnancies and neonatal outcomes

Objective: We aimed to evaluate the differences in obstetrics and neonatal outcomes, such as mode of delivery, gestational diabetes mellitus, preeclampsia, and infant birth weight between pregnancies with normal and insufficient vitamin D levels. Methods: The study was designed as a retrospective study. One hundred and seventy-nine pregnant women who were followed up at our clinic and whose vitamin D levels were evaluated in each trimester were included. All patients were administered 1200 IU/day beginning from the 12 weeks of gestation in accordance with the national guidelines. Vitamin D levels above 20 ng/ml were defined as sufficient, and those below 20 ng/ml were defined as insufficient. Results: The median vitamin D level in the third trimester was significantly higher than that in the first and second trimesters (p<0.001). There was a moderate positive correlation between vitamin D levels in infant cord blood at the time of birth and vitamin D levels in the third trimester (p<0.001, R=0.496). Birth weights of the patients with insufficient vitamin D levels in the first trimester but with sufficient neonatal cord blood levels as a result of treatment were significantly higher compared to those in patients with insufficient cord blood vitamin D levels (3327 g vs. 3133 g, p=0.030). Conclusion: This study observed that neonatal cord blood vitamin D level is a better indicator than antenatal vitamin D levels. Regardless of first-trimester vitamin D levels, infant birth weights were significantly higher in the group with sufficient neonatal cord blood levels

Data accompanying the research on: Can postpartum blood loss be predicted via uterine artery Doppler analysis?

Herein, we attempted to predict hemoglobin (Hb) decrease by observing uterine artery Doppler indices during the early postpartum period. It was a prospective cohort study. After delivery, while the patient was in the delivery room we measured uterine size and uterine artery doppler parameters. Complete blood counts were obtained from the patients at postpartum hours 4 and 24 and the results were recorded. The patients’ postpartum and prenatal Hb and Htc values were compared via uterine artery indices

Data accompanying the research on: Does Betamethasone therapy impact fetal multivessel doppler parameters?

This was a prospective cohort study. During March 2018–March 2019, 27 singleton pregnancies between 28 and 34 gestational weeks with a diagnosis threat of preterm birth were included prospectively. To be eligible, patients had to have received betamethasone and a loading dose of nifedipine for tocolysis, followed by hydration and maintenance nifedipine therapy for 48 h. Betamethasone (Celestone Cronodose, Schering-Plough, İstanbul, Turkey) was administered as two doses of 12 mg each, administered 24 h apart. Fetuses, who had intrauterine growth restriction (IUGR), oligohydramnios, polyhydramnios, or fetal anomaly were excluded from the study. Other maternal indications for exclusion were: preeclampsia, eclampsia, HELLP syndrome, premature preterm rupture of membranes, placenta previa, or any chronic maternal disease. Patients with diabetes mellitus (gestational or pregestational) were not included in the study. We prospectively evaluated fetal main pulmonary artery (MPA), left and right pulmonary artery (PA), left myocardial performance index (MPI, TEI index), tricuspid valve (TV), umbilical artery (UmA), middle cerebral artery (MCA), and ductus venous (DV) parameters before and at 48 h and 7 days after steroid administration. The Doppler indices of interest included Peak Systolic Velocity (PSV), Resistance Index (RI), Pulsatility Index (PI), Systolic/Diastolic ratio (S/D ratio), Acceleration Time/Ejection Time Ratio (AT/ET ratio) (MPA), E/A ratio (TV), left ventricle TEI index parameters (isovolumetric contraction time (ICT), isovolumetric relaxation time (IRT), ejection time (ET), and DV A wave

Investigation of glass/epoxy laminate composites reinforced with bio-particles under mechanical loading

In this paper, the effects of particle reinforcement on the tensile, compression and flexural properties, as well as the influence of cross head speed on the quasi-static punch shear properties of glass/epoxy composites are investigated. Laminated composites, which are manufactured by hand lay-up method consist of six layers of stitched glass fibers. As the particle reinforcement materials, pinecone and acorn powders with 1, 2, 3, 4 and 5 wt% ratios are used for the manufacturing of composites. The quasi-static punch shear behaviour of composites is elucidated at a room temperature through the force - deformation curves and the energy graphs at different test speeds (i.e., 1, 10 and 20 mm min-1). According to the experimental findings of quasi-static punch shear tests, it is concluded that the maximum contact force of each composite increases along with the punch shear test speed. Compressive strength of the acorn reinforced specimens shows their highest compressive value at the particle amount of 5 wt%, while pinecone-reinforced composites exhibit their highest compressive strength at the particle ratio of 2 wt%

An investigation of the mechanical characteristics of natural particle-reinforced glass and epoxy composites after immersion in acidic and basic aging solutions

This study aimed to ascertain the alterations in aging responses of fiber-reinforced composites, as well as the effects of their natural particle reinforcement, through exposure to acidic and alkaline solutions. Specimens were produced with 0 wt. % (neat), 1 wt. %, 2 wt. % and 3 wt. % particle ratios from acorn and pinecone particles. A particle content of 2 wt. % was determined to yield the best mechanical properties in all mechanical tests conducted for pinecone reinforcement. The highest improvement in strength, observed in 3 wt. % pinecone-reinforced composites, reached 22.5% at flexural strength. HCl and NaOH diluted in water were chosen as aging solutions. Mechanical tests were repeated at different stages of aging. According to the findings, 1 wt. % particle-reinforced composites showed better resilience to the mechanical property reduction effect of aging compared to the 2 wt. % and 3 wt. % particle-reinforced composites. At a particle ratio of 2 wt. %, the acorn-reinforced specimens exhibit their highest maximum penetration force, which is 5% higher than that of the 0 wt. % composite, consistent with the results of tensile and compressive tests. Highlights: Composite material was manufactured by hand lay-up and vacuum bagging method. Specimens were aged using acid and base solutions. Tensile, compressive, and bending results were obtained depending on particle type and ratio. Tensile, compressive, and bending strengths of composites were compared according to various aging times