45 research outputs found

    CAST - A CERN experiment to search for solar axions

    Get PDF
    The CAST experiment at CERN is the only running solar axion telescope. The first results obtained so far with CAST - PHASE I is presented, which compete with the best astrophysically derived limits of the axion-to-photon coupling. The ongoing PHASE II of the experiment as well as the scheduled upgrades, which improve the axion discovery potential of CAST, are discussed.Baklan Physical Uniaon; Türk Fizik Derneği; İstanbul Üniversitesi; Yıldız Teknik Üniversitesi

    Detection of 13th chromosome deletion frequency by fluorescent in situ hybridization method in patients with multiple myeloma

    Get PDF
    INTRODUCTION: Multiple myeloma (MM) is a malignant hematological disease characterized by malignant proliferation of a single plasma cell clone leading to monoclonal protein in plasma or urine. Presence of monoallelic loss of chromosome 13 (del13) or loss of long arm (del13q) indicates poor prognostic outcome in patients treated with standard chemotherapy. Del13/del13q is detected by FISH method in approximately half of newly diagnosed MM patients. METHODS: 42 patients diagnosed with MM according to the criteria of the International myeloma working group and treated at research and education hospital, were included in this study. Clinical, laboratory, pathological data were analyzed retrospectively and genetic data obtained by FISH method. RESULTS: 26 patients were female (61.9%) and 16 were male (38.1%). The mean age was 62. Del13 results were obtained in 30 of 42 patients, while positive in 6 patients (20%) negative in 24 patients (80%). Among the 30 patients with chromosome 13 results, 4 had IgA, 19 had IgG type monoclonal protein. All of the 6 patients with del13 were IgG myeloma (2 kappa, 3 lambda). DISCUSSION AND CONCLUSION: Compared to the recent studies, del13 is lower in our study. In many studies, del13 has been found in rates ranging from 30-50%. Although the rate of 20% we found is lower than the data in the literature, it is valuable in terms of reflecting the frequency of del13 in myeloma patients. Therefore, we strongly recommend that conventional karyotyping and FISH analysis of common chromosomal abnormalities be performed in newly diagnosed MM patients

    Solar axion search with the CAST experiment

    Get PDF
    Şenel Boydağ, Fatma (Dogus Author), Çetin, Serkant Ali (Dogus Author), Hikmet, İskender (Dogus Author) -- Proceedings of the 34th International Conference in High Energy Physics : (ICHEP08) Philadelphia, Pennsylvania, July 29 - August 5, 2008.The CAST (CERN Axion Solar Telescope) experiment is searching for solar axions by their conversion into photons inside the magnet pipe of an LHC dipole. The analysis of the data recorded during the first phase of the experiment with vacuum in the magnet pipes has resulted in the most restrictive experimental limit on the coupling constant of axions to photons. In the second phase, CAST is operating with a buffer gas inside the magnet pipes in order to extent the sensitivity of the experiment to higher axion masses. We will present the first results on the 4He data taking as well as the system upgrades that have been operated in the last year in order to adapt the experiment for the 3He data taking. Expected sensitivities on the coupling constant of axions to photons will be given for the recent 3He run just started in March 2008

    The COVID-19 pandemic: a letter to G20 leaders

    Get PDF

    INVESTIGATION OF THE EFFECT OF ALLOY ELEMENTS IN STEEL SHEETS USED IN THE AUTOMOTIVE INDUSTRY

    No full text
    In this study, analyses were made using the finite element method and the formability were examined of six different materials used in the automotive industry. Deep drawing simulation was made of materials with a specific geometry and initial thickness of 1.5 mm and forming limit diagrams were obtained. The formabilities were compared over the diagrams plotted separately for each material and the deformation difficulties were evaluated. According to the analysis results, It was determined Niobium, Titanium and Vanadium elements had negative effects and Aluminum element had a positive effect on formability
    corecore