Outpatient management of steroid-induced hyperglycaemia and steroid-induced diabetes in people with lymphoproliferative disorders treated with intermittent high dose steroids

High dose steroids (HDS) are used in the treatment of haematological malignancies. The reported risk of steroid-induced diabetes (SID) is high. However, screening is not consistently performed. We implemented a protocol for detection and management of SID and steroid-induced hyperglycamia (SIH) in haematology outpatients receiving HDS. Eighty-three people were diagnosed with a lymphoproliferative disorder, of whom 6 had known Type 2 diabetes. Fifty-three people without known diabetes were screened by HbA1c and random venous plasma glucose. All patients (n = 34) subsequently prescribed HDS checked capillary blood glucose (CBG) pre-breakfast and pre-evening meal. Treatment algorithms used initiation and/or dose titration of gliclazide or human NPH insulin, aiming for pre-meal CBG 5–11 mmol/l. Type 2 diabetes was identified in 4/53 people screened (7.5%). Of 34 people treated with HDS, 17 (44%) developed SIH/SID. All 7 people with Type 2 diabetes developed SIH and 3 required insulin. Of 27 people without known diabetes, 8 (30%) developed SID and 1 required insulin. Pre-treatment HbA1c was higher in people who developed SID compared to those that did not (p = 0.002). This is the first report of a SID/SIH detection and treatment protocol for use in people with lymphoproliferative disorders receiving intermittent HDS, demonstrating its feasibility and safety

IT-profilen vid Fysisk Planering

Förordet sidan 1 i rapporten: Vid en personalkonferens våren 2000 fördes samtal om hur Blekinge Tekniska Högskolas profilering mot tillämpad IT kunde förverkligas inom utbildning och forskning i Fysisk planering. En arbetsgrupp tillsattes för att belysa frågan. Sammankallande blev Anders Törnqvist, professor, Fysisk planering, övriga deltagare Anders Wellving, lektor Fysisk planering, Jan-Evert Nilsson, professor, Centrum för Territoriell Utvecklingsplanering samt Johan Cronehed, doktorand, Fysisk planering/Socialantropologi, Lunds universitet. Gruppen kom fram till att varje deltagare skulle skriva ett debattinlägg utifrån sina professionella kunskaper och värderingar. Dessa debattinlägg är samlade i denna rapport tillsammans med gruppens slutsatser och förslag. Eva Öresjö Professor, prefekt Innehåll, de olika bidragens titlar: "Fysiska Planerare i behärskandet av både estetik och teknik" av Johan Cronehed "Planeringens inträde i den virtuella världen" av Jan-Evert Nilsson "IT och planerarrollen" av Anders Törnqvist "Mot en tydligare IT-profil vid Institutionen för Fysisk Planering" av Anders Wellvin