762 research outputs found
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Ter gelegenheid van zijn afscheid als hoogleraar in de Urologie, in het bijzonder Functiestoornissen van de Lagere Urinewegen aan de Universiteit Leiden op vrijdag 2 september 2016LUMC / Geneeskund
Cohere: Privacy Management in Large Scale Systems
The need for a privacy management layer in today's systems started to
manifest with the emergence of new systems for privacy-preserving analytics and
privacy compliance. As a result, we began to see many independent efforts
emerge that try to provide system support for privacy. Recently, the scope of
privacy solutions used in systems has expanded to encompass more complex
techniques such as Differential Privacy (DP). The use of these solutions in
large-scale systems imposes new challenges and requirements. Careful planning
and coordination are necessary to ensure that privacy guarantees are maintained
across a wide range of heterogeneous applications and data systems. This
requires new solutions for managing shared application state and allocating
scarce and non-replenishable privacy resources. In this paper, we introduce
Cohere, a new data management system that simplifies the use of DP in
large-scale systems. Cohere implements a unified interface that allows
heterogeneous applications to operate on a unified view of users' data. Cohere
further extends existing accounting systems with the ability to manage and
optimally allocate shared privacy resources, i.e., budget, under complex
preferences. We show that Cohere can effectively enable advanced privacy
solutions in existing large-scale systems with minimal modifications to
existing data management systems and with moderate overhead
Soft controls and employee well-being:An analysis of SMEs in Europe
How can small and medium-sized enterprises (SMEs) take care of their employees’ wellbeing so that they can retain a productive and satisfied workforce? The present study examines the relation between soft controls and the well-being of employees in small and medium-sized enterprises. Soft controls are defined in terms of social safety, autonomy, support and empowerment. We use the job demands resources (JD-R) model and the self determination theory (SDT) to develop hypotheses on how soft controls are related to well-being. The research was based on data collected from the European Working Conditions Survey 2015. The sample consisted of 9255 salaried employees, working in SMEs across 35 European countries. Structural equation modelling showed that soft controls affect employee well-being. In European SMEs especially social safety is an important form of soft control. Social safety appears to promote employees’ jobsatisfaction and engagement, while preventing burnout and workaholism
Soft controls and employee well-being:An analysis of SMEs in Europe
How can small and medium-sized enterprises (SMEs) take care of their employees’ wellbeing so that they can retain a productive and satisfied workforce? The present study examines the relation between soft controls and the well-being of employees in small and medium-sized enterprises. Soft controls are defined in terms of social safety, autonomy, support and empowerment. We use the job demands resources (JD-R) model and the self determination theory (SDT) to develop hypotheses on how soft controls are related to well-being. The research was based on data collected from the European Working Conditions Survey 2015. The sample consisted of 9255 salaried employees, working in SMEs across 35 European countries. Structural equation modelling showed that soft controls affect employee well-being. In European SMEs especially social safety is an important form of soft control. Social safety appears to promote employees’ jobsatisfaction and engagement, while preventing burnout and workaholism
Thalamic Lesions in Vascular Dementia: Low Sensitivity of Fluid-Attenuated Inversion Recovery (FLAIR) Imaging
Background and Purpose—The criteria of the National Institute of Neurological Disorders and Stroke (NINDS)–
Association Internationale pour la Recherche et l’Enseignement en Neurosciences (AIREN) include thalamic lesions for
the diagnosis of vascular dementia (VaD). Although studies concerning VaD and brain aging advocate the use of
fluid-attenuated inversion recovery (FLAIR) or T2-weighted images (T2-WI) to detect ischemic lesions, none compared
the sensitivity of these sequences to depict thalamic lesions.
Methods—We performed a blinded review of T2-WI and FLAIR images in 73 patients fulfilling the radiological part of the NINDS-AIREN criteria (mean age, 71 years; range, 49 to 83 years). This sample was drawn from a large multicenter trial on VaD and was expected to have a high prevalence of thalamic lesions. In a side-by-side review, including T1-weighted images as well, lesions were classified according to presumed underlying pathology.
Results—The total number of thalamic lesions was 214. Two hundred eight (97%) were detected on T2-WI, but only 117
(55%) were detected on FLAIR ( 2 5.1; P 0.05). Although the mean size of lesions detected on T2-WI and not on FLAIR (4.4 mm) was significantly lower than the mean size of lesions detected on both sequences (6.7 mm) (P 0.001), 5 of the 29 lesions 10 mm on T2-WI were not visible on FLAIR. FLAIR detected only 81 (51%) of the 158 probable ischemic lesions and 30 (60%) of the 50 probable microbleeds.
Conclusions—FLAIR should not be used as the only T2-weighted sequence to detect thalamic lesions in patients suspected
of having VaD
Van coronacrisis naar kansen: financiële maatregelen in coronatijd
Coherent privaatrech
Goodwill and value creation of acquisitions
In 2001, some important changes took place in the US accounting regime. As a result of these changes, acquiring companies are obliged to provide more extended as well as more uniform information concerning the mergers and acquisitions in their annual accounts. The intention of this research is to gain an insight into the information content of purchased goodwill with regard to the value creation of the acquisition for the business combination. This research contains two studies. The first study investigates whether the new regulation affects reporting on goodwill. The second study focuses attention on goodwill under the new regime as a measure of value creation.LEI Universiteit LeidenCoherent privaatrech
Zachte slaag- en faalfactoren bij fusies en overnames in kaart: op weg naar de Soft Due Diligence Check
Coherent privaatrech
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