The Redskin 1928

1928 yearbook for Cle Elum High School, Cle Elum Washington.https://digitalcommons.cwu.edu/roslyn_hs_yearbooks/1015/thumbnail.jp

Iwa

1907 yearbook for Cle Elum High School, Cle Elum Washington.https://digitalcommons.cwu.edu/roslyn_hs_yearbooks/1014/thumbnail.jp

Mandelbrot's 1/f fractional renewal models of 1963-67: The non-ergodic missing link between change points and long range dependence

The problem of 1/f noise has been with us for about a century. Because it is so often framed in Fourier spectral language, the most famous solutions have tended to be the stationary long range dependent (LRD) models such as Mandelbrot's fractional Gaussian noise. In view of the increasing importance to physics of non-ergodic fractional renewal models, I present preliminary results of my research into the history of Mandelbrot's very little known work in that area from 1963-67. I speculate about how the lack of awareness of this work in the physics and statistics communities may have affected the development of complexity science, and I discuss the differences between the Hurst effect, 1/f noise and LRD, concepts which are often treated as equivalent.Comment: 11 pages. Corrected and improved version of a manuscript submitted to ITISE 2016 meeting in Granada, Spai

Observation-domain sidereal filtering for high-rate GPS precise point positioning

Accurate and timely determination of coseismic displacement (the quasi-permanent displacement of the ground caused by an earthquake) is crucial for tsunami warning and situational awareness systems. Seismometers measure acceleration or velocity very precisely. However, the process of integrating such data to yield displacement data is difficult and error-prone. In contrast, The Global Positioning System (GPS) can measure displacement directly, but is also subject to errors, one of which is multipath. Multipath errors can lead to errors in the measurement of small displacements or obscure the displacement entirely. Errors due to multipath are highly dependent on the geometry of GPS satellite orbits and surrounding reflectors relative to the receiving antenna itself. Each satellite has a ground track repeat period of approximately one sidereal day. Hence, this relative satellite-reflector geometry will repeat with the same period. Using this fact, it is possible to identify and remove the error signature induced by multipath by analysing data from adjacent days, yielding an improved time series of displacements and hence a more discernible coseismic offset. This process is commonly known as 'sidereal filtering'. This thesis describes a sidereal filter algorithm that attempts to remove the multipath error signature from the GPS measurements themselves before processing them rather than from the resulting position time-series. It is shown to generally produce a more stable position time series over periods from a few tens to a few hundred seconds, remove high-frequency multipath error more effectively, yield better stability during satellite outages and measure small centimetre-level displacements more accurately than a position-domain sidereal filter. However, results are inconclusive when applying the algorithm to the measurement of the coseismic displacements of a real earthquake, but it is demonstrated that an observation-domain sidereal filter is better at enabling one to distinguish certain types of seismic wave from a position time series

Differentiation of dementia with Lewy bodies from Alzheimer's disease using a dopaminergic presynaptic ligand

Background: Dementia with Lewy bodies (DLB) is one of the main differential diagnoses of Alzheimer's disease (AD). Key pathological features of patients with DLB are not only the presence of cerebral cortical neuronal loss, with Lewy bodies in surviving neurones, but also loss of nigrostriatal dopaminergic neurones, similar to that of Parkinson's disease (PD). In DLB there is 40-70% loss of striatal dopamine.Objective: To determine if detection of this dopaminergic degeneration can help to distinguish DLB from AD during life.Methods: The integrity of the nigrostriatal metabolism in 27 patients with DLB, 17 with AD, 19 drug naive patients with PD, and 16 controls was assessed using a dopaminergic presynaptic ligand, I-123-labelled 2beta-carbomethoxy-3beta-(4-iodophenyl)-N-(3-fluoropropyl)nortropane (FP-CIT), and single photon emission tomography (SPET). A SPET scan was carried out with a single slice, brain dedicated tomograph (SME 810) 3.5 hours after intravenous injection of 185 MBq FP-CIT. With occipital cortex used as a radioactivity uptake reference, ratios for the caudate nucleus and the anterior and posterior putamen of both hemispheres were calculated. All scans were also rated by a simple visual method.Results: Both DLB and PD patients had significantly lower uptake of radioactivity than patients with (p<0.01) and controls (p<0.001) in the caudate nucleus and the anterior and posterior Putamen.Conclusion: FP-CIT SPET provides a means of distinguishing DLB from AD during life

How do supply chain choices affect the life cycle impacts of medical products?

The natural resource based view (NRBV) of organisations suggests that there are two main models used by businesses to achieve short-term sustainability outcomes. They are the product stewardship and pollution prevention models. Here is the case of a New York-based wholesaler of medical supplies. The business aims to develop a more environmentally sustainable supply chain for one of its products - an emesis basin. The emesis basin is currently only offered in high-density polyethylene (HDPE) plastic, which has negative effects on the natural environment. This study aimed to assess how the focus of the business’ new business model might affect the overall life cycle impacts of this product. To achieve this, we compared the environmental impacts of the conventional product (Scenario 1– an HDPE basin) with equivalent products supplied via pollution prevention (Scenario 2 – a bioplastic basin) and product stewardship (Scenario 3 – green supply chain management and improvements) scenarios, as well as a combination scenario (Scenario 4). The results show that, in line with expectations, the pollution prevention option – switching to a bioplastic product – has the lowest environmental impacts. Unexpectedly though, the product stewardship option had a greater impact on the natural environment than the conventional HDPE, business-as-usual option. We suggest there may greater environmental gains to be obtained by focusing on one’s core business, than by extending influence to the entire supply chain