Perbedaan Kadar Asam Urat Pada Seseorang Dengan Hipertensi Dan Non Hipertensi Di Kecamatan Jebres Kota Surakarta

Backgrounds : Hypertension is the number of agreements based on clinical evidence, consensus, and epidemiological studies of the meta-analysis, which is an increase of blood pressure above or equal to 140/90 mmHg. Uric acid is the end product of purine metabolism. Hypertension can lead to increased levels of uric acid in the blood. Increased levels of uric acid in the blood causes a decrease in renal perfusion, thus stimulating the reabsorption of uric acid and the end result is an increase in levels of uric acid in the blood. Purpose : The purpose of the research is to know the differences in levels of uric acid in a person with hypertensive and non-hypertensive in District Jebres Surakarta city Method : This research is a cross sectional analytic, puskesmas election made after conducting a preliminary study on the data the incidence of hypertensive patients in Surakarta followed by sampling using consecutive sampling. Data obtained from the measurement directly on the sample. Results : Statistical analysis was performed with Fisher test p value = 0.00, the value of RP = 3.4, and the value of CI is 2.4 to 4.8, which means there are significant differences uric acid levels in a person with hypertensive and non-hypertensive. Conclusions : There is a significant difference in levels of uric acid in a person with hypertensive and non-hypertensive in District Jebres, Surakarta city Keywords : : Hypertension, uric acid level

Hubungan antara Frekuensi Denyut Jantung dengan Volume Oksigen Maksimal pada Anggota Pencak Silat Persaudaraan Setia Hati Terate Universitas Muhammadiyah Surakarta.

Volume Oksigen Maksimal (VO2 Maks) merupakan suatu ukuran dari kapasitas sistem kardiovaskuler yang menunjukkan tingkat kebugaran seseorang. Banyak faktor yang mempengaruhi VO2 Maks, salah satunya adalah perubahan frekuensi denyut jantung akibat aktivitas fisik. Penelitian ini bertujuan untuk mengetahui apakah ada hubungan antara frekuensi denyut jantung dengan Volume Oksigen Maksimal tersebut. Desain penelitian menggunakan metode penelitian analitik observasional non-ekperimental dengan rancangan cross sectional. Jumlah sampel penelitian sebanyak 33 anggota pencak silat dengan teknik purposive sampling dan dilakukan pengukuran VO2 Maks di laboratorium Fisiologi Universitas Muhammadiyah Surakarta. Data dianalisis dengan uji korelatif Pearson dengan program SPSS 17.0 for windows. Hasil penelitian menunjukkan bahwa nilai p = 0.000 (p < 0.05) yang menunjukkan terdapat korelasi bermakna antara dua variabel yang diuji dan nilai korelasi Pearson sebesar – 0.747 yang menunjukkan korelasi negatif dengan kekuatan korelasi yang kuat. Penelitian ini menyimpulkan bahwa terdapat korelasi yang bermakna antara frekuensi denyut jantung dengan Volume Oksigen Maksimal pada Anggota Pencak Silat Persaudaraan Setia Hati Terate Universitas Muhammadiyah Surakarta

Uji Aktivitas Antihelmintik Ekstrak Akar Pepaya (Carica Papaya L.) Terhadap Cacing Ascaris Suum (Studi Invitro)

Background: Investation of Ascaris sp. have a serious impact on patients and society. The prevalence of intestinal worms in Indonesia was still very high, especially in poor communities with bad sanitation. Indonesian people have known traditional medicine that can be used as anthelmintic, such as papaya roots (Carica papaya L.). The papaya root extract contains papain, tannin and saponins that have anthelmintic effects. Objective: To investigate the efficacy of papaya roots extract (Carica papaya L.) on the death of Ascaris suum. Method: This study was an experimental laboratory with post only controlled group design. The subjects wereAscaris suumworms. Papaya root extracts with the concentrations of 10%, 20%, and 50% were tested for their anthelmintic activity by dipping the worms into the treatment solution. Observations were made every 2 hours until all the worms die 100%.The data were analyzed withstatistical software for Windows. Result: Papaya roots extract hadan anthelmintic effect againts Ascaris suum(studi in vitro). The result of p <0,05 in post-hoc analysis of LSD (Least Significant Diference) so that there is significant difference between negative control group and treatment group. Conclusion: It was concluded that papaya roots extract has an anthelmintic effect againts Ascaris suum

Korelasi Antara Penurunan Laju Filtrasi Glomerulus Dengan Beratnya Anemia Pada Penyakit Ginjal Kronik Di RSUD DR. Sayyidiman Magetan

Latar Belakang: Penyakit ginjal kronik (PGK) merupakan masalah kesehatan diseluruh dunia yang semakin meningkat jumlahnya. Penurunan laju filtrasi glomerulus, serta kelainan struktur maupun fungsi ginjal yang irreversible dan berlangsung kronik menyebabkan berbagai manifestasi salah satunya anemia. Diketahui bahwa penurunan laju filtrasi glomerulus yang berlanjut mengakibatkan defisiensi hormoneritropoetin karena kerusakan ginjal yang kronik. Tujuan Penelitian: Untuk mengetahuikorelasi antara penurunan laju filtrasi glomerulus dengan beratnya anemia pada penyakit ginjal kronik (PGK) di RSUD Dr. SayyidimanMagetan. Subjek dan Metode Penelitian: Rancangan penelitian ini adalah observasionalanalitik yang dilakukan dengan metode cross sectional. Pengambilan sampel dengan teknik purposive sampling. Teknik analisa data yang digunakan adalah korelasi spearman’s. Hasil Penelitian: Analisis statistik diperoleh hasil dengan nilai Rrho =0,302 dan nilai P = o,o19. Kesimpulan: Terdapat korelasi antara penurunan laju filtrasi glomerulus dengan beratnya anemia pada penyakit ginjal kronik di RSUD Dr. SayyidimanMagetan

Perbedaan Kadar Hemoglobin, Hematokrit dan Trombosit Antara Pasien Preeklampsia dan Tidak Preeklampsia

Background . Preeclampsia is a major pregnancy complication which incidence is increasing throughout the world (Serudji et al, 2014). Data from the World Health Organization (WHO) (2015), globally maternal mortality in the world is 303,000. In the previous study there were several speculations and conclusions about hemoglobin, hematocrit and platelet levels in patients with preeclampsia and patients without preeclampsia (Tiaranissa et al, 2014). Tiaranissa et al (2014) and Pakniat et al (2016) state that hemoglobin is increased in preeclamptic patients. Hetina et al (2015) stated that there was no difference in hemoglobin levels in preeclamptic patients and without preeclampsia. Giyanto et al (2015) stated that hematocrit was increased in preeclampsia patients. Khoigani et al (2012) decreased hematocrit. Yusrianty et al (2014) there were no differences in platelets in preeclampsia and without preeclampsia. Monteiro (2014) stated that platelets decreased in preeclamptic patients. Aim. The general objective of this study is to determine whether there are differences in hemoglobin, hematocrit and platelet levels between preeclamptic patients and not preeclampsia. The specific purpose of this study was to determine the rate of hemoglobin , hematocrit and platelet between patients with preeclampsia and without preeclampsia. Method. The type of research used is observational analytic with a Case control approach . The sample that used is 88 samples and were divided into target samples and control samples used consecutive sampling technique . The data was obtained from the patient's medical record during the hospitalization. Results. After analyzing the data using the test Unpaired T, the results of hemoglobin levels obtained p = 0.003, p 0.05 . Conclusion. Hemoglobin, hematocrit and platelet levels have difference in preeclampsia patients and without preeclampsia. Hemoglobin levels in preeclampsia patients are higher than those without preeclampsia. Hematocrit levels in preeclampsia patients are higher than those without preeclampsia. The level of platelet in patients with preeclampsia and without preeclampsia are not different. Keywords: Preeclampsia, Without Preeclampsia, Hemoglobin, Hematocrit, Platele

Hubungan Diabetes Melitus Terkontrol Dan Tidak Terkontrol Dengan Faktor Risiko Obstructive Sleep Apnea (Osa)

Backgrounds: Diabetes mellitus (DM) is a chronic disease that occurs when the pancreas cannot produce insulin or when there is a disruption in the body's metabolism. DM can be characterized by with a polydipsia , polyphagia, polyuria and weight loss. The weight loss is due to a decrease in muscle mass. If the muscle mass reduction occurs in nasopharynx and oropharynx, the muscle will collapse. This incident can lead to Obstructive sleep apnea ( OSA). Purpose: This research was held to answer the question is there a associated a significant diabetes mellitus patients with risk factors for OSA in Prolanis in Surakarta. Method: This research was designed using analytic observational with cross- sectional approach with samples 112 respondents. Data were analyzed by chi- square test with SPSS17.0 for windows. Results: There is a associated between DM Controlled and uncontrolled with risk OSA; p value 0,037 and Ratio Prevalens (RP) 1,524 interval confidence 95% 1,024 to 5,980. Conclusion: There is relathionship between Diabetes mellitus controled and uncontroled with risk obstructive sleep apnea

Hubungan Antara Kualitas Tidur Dengan Kadar Glukosa Darah Pada Penderita Diabetes Melitus Tipe 2 Di RSUD Dr. Moewardi

Latar Belakang: Diabetes melitus tipe 2 adalah penyakit yang berkembang dan dapat dipengaruhi oleh gaya hidup. Setiap tahun 7 juta orang menderita diabetes melitus. Indonesia termasuk dalam 10 negara dengan penderita diabetes terbanyak di dunia. Penelitian sebelumnya menunjukan bahwa penderita diabetes dengan kualitas tidur buruk berhubungan dengan kontrol glukosa darah yang buruk. Kualitas tidur mempengaruhi kesehatan fisiologis dan psikologis. Gangguan tidur dapat meningkatkan resistensi insulin. Metode: Observasi analitik dengan pendekatan cross sectional. Jumlah sampel penelitian sebanyak 80 orang dengan teknik pengambilan sampel purposive sampling. Instrumen yang digunakan adalah kuesioner dan data rekam medik. Data dianalisis dengan uji chi square. Hasil: Uji chi square menunjukan nilai p = 0,043 (p <0,05). Hal ini berarti H0 ditolak dan H1 diterima. Kesimpulan: Terdapat hubungan signifikan antara kualitas tidur dengan kadar glukosa darah pada penderita diabetes melitus tipe 2

Hubungan Antara Rasio Kadar Kolesterol Total Terhadap High-Density Lipoprotein (HDL) Dengan Kejadian Penyakit Jantung Koroner Di RSUD Dr. Moewardi

Latar Belakang: Penyakit kardiovaskular merupakan penyebab kematian peringkat pertama di dunia, dan menyebabkan sepertiga dari semua kematian secara global. Hampir 50% total kematian penyakit kardiovaskular disebabkan oleh PJK. Kolesterol merupakan jenis lipid yang relatif mempunyai makna klinis penting sehubungan dengan aterogenesis pada PJK. Rasio kadar kolesterol total terhadap HDL merupakan prediktor yang baik untuk mendeteksi dini risiko PJK. Rasio dapat diperoleh dengan cara membagi kadar kolesterol total dengan HDL. Metode: Observasi analitik dengan pendekatan cross sectional. Jumlah sampel penelitian sebanyak 90 orang dengan teknik pengambilan sampel purposive sampling. Instrumen yang digunakan adalah data rekam medik. Data dianalisis dengan uji chi square. Hasil: Uji chi square menunjukan nilai p = 0,030 (p <0,05). Hal ini berarti H0 ditolak dan H1 diterima. Kesimpulan: Berdasarkan analisis data, terdapat hubungan signifikan antara rasio kadar kolesterol total terhadap high-density lipoprotein (HDL) dengan kejadian penyakit jantung korone

Hubungan Antara Anemia, Usia Ibu, dan Riwayat Kehamilan Multipara dengan Kejadian Persalinan Preterm

Anemia in pregnancy is a condition with hemoglobin levels 35 years. The purpose of this study was to determine the relationship between anemia, maternal age, history of multipara pregnancy with the incidence of preterm labor. The method used in this study used a cross-sectional study design and was conducted in December 2018 at the RSUD dr. Soeselo, Tegal Regency. The sample in the study amounted to 106 respondents obtained using non probability sampling techniques with consecutive sampling technique. The data used in the secondary data is the data obtained from the results of the medical recap on January 1, 2016 - December 31, 2017. Data were analyzed by univariate, bivariate, multivariate tests. The Chi square test results showed that there was a relationship between anemia and the incidence of preterm delivery in dr. Soeselo Tegal Regency with a p-value of 0.047. There is a relationship between the age of the mother and the incidence of preterm labor in RSUD dr. Soeselo Tegal Regency with a p-value of 0.035. There is a relationship between the history of multiparous pregnancy and the incidence of preterm delivery in the RSUD dr. Soeselo Tegal Regency with a p-value of 0.028. The conclusion of this study is that there is a significant relationship between the age of the mother and the incidence of preterm labor

Perbedaan Kolesterol Total Pada Dewasa Obesitas Dan Non Obesitas

THE DIFFERENCE OF TOTAL CHOLESTEROL IN ADULT OBESITY AND NO OBESITY Fitri, Safari Wahyu Jatmiko Faculty of Medicine, Muhammadiyah University Surakarta ABSTRACT Background: Being overweight is a major factor for a number of chronic diseases. Obesity in young adults is associated with an increased risk of coronary heart disease, hypertension, hypercholesterolemia, and metabolic disorders. The prevalence of obesity in Indonesia in 2013 was 19.7% in men and 32.9% in women. Permanent obesity and excessive food intake can cause a disruption of the metabolic system in the form of hypercholesterolemia. Obesity can cause interference with the regulation of fatty acids which will increase the levels of triglycerides and ester cholesterol. Objective: To determine differences in total cholesterol in obese and non-obese adults. Method: This study was an observational analytic study with a cross sectional approach conducted at Sibela Health Center in Jebres District, Surakarta City. The sample size used was 122 samples, consisting of obesity 61 samples and non obesity 61 samples with consecutive sampling technique. Data obtained from primary data. Results: This study was conducted at the Sibela Community Health Center, Jebres District, Surakarta City in March 2019. Respondents who came to the Puskesmas with an age range of 25-65 years. The results of the analysis using unpaired t test obtained differences in the average total cholesterol in obesity and non-obese at 56,115, with a value of p = 0.000 (p <0.05). Conclusion: There are differences in the average value of total cholesterol in obese and non obese adults of 56,115. Keywords: Obesity, Hypercholesterolemia, Total cholestero