Hubungan antara Asupan Protein, Zat Besi dan Vitamin C dengan Kadar Hb pada Anak Umur (7-15) tahun di Desa Sidoharjo, Samigaluh, Kulon Progo

The high risk age of malaria infection in Kulonprogo is 5-14 year old. Anemia is a common condition that caused by chronic infection of malaria. Anemia worsefor patient with malnutrition. This research aims to reveal how dietary intake of children, especially protein, vitamin C and iron intake on the incidence of anemia in aged 7-15 years in malaria endemic malaria. This study use cross sectional - retrospectif design. The research subjects were 61 children (class 4-6 elementary school) from 6 hamlets. They are healthy children, no history of chronic illness other than malaria or kongenita disease. Children fill list of food intake for 7 days. After that weight and height were measured and blood Hb was deternined by Sahli method. Food intake was analyzed using Food Proseccor I. To analyze the relationship between protein intake, vitamin C and iron and hemoglobin concentration were used Pearson test.The result showed that the average ofprotein, iron and vitamin C were 25.064 ± 10.055 g (38.9% RDA (RecommmendedDaily Allowance), 6.523 ± 2.635 mg (56.33% RDA), 69.5% o RDA consecutively. The mean of hemoglobin level was 10.3 ± 1.2 grams / dl. The statistical analysis showed that there were linear relationship between vitamin C and iron (r = 0,765), between iron intake and hemoglobin (r = 0.675). It can be concluded that the low of intake of protein, iron and vitamin C associated with incidence of anemi.Kelompok usia risiko tinggi infeksi malaria di Kulonprogo adalah 5-14 thn. Anemia merupakan kondisi umum yang terjadi akibat infeksi kronis malaria. Anemia akan makin berat bila penderita menderita kekurangan gizi dan protein. Penelitian ini bertujuan untuk mengungkap hubungan antara asupan makanan anak terutama protein, vitamin C, zat besi terhadap kejadian anemia pada usia 7-15 tahun di daerah endemik malaria. Penelitian menggunakan rancangan cross sectional - retrospectif pada sampel terpilih. Subyek penelitian sebanyak 61 anak (kelas 4-6 sekolah dasar) berasal dari 6 dusun. Anak sehat tidak memiliki riwayat penyakit menahun selain malaria atau penyakit kongenital. Anak mengisi daftar asupan makanan selama 7 hari, setelah itu diukur berat dan tinggi badan, darah diperiksa kadar Hbnya dengan metoda Sahli. Asupan makanan dianalisis dengan Food Proseccor I, untuk mengetahui persen asupan makanan perhari. Analisis hubungan asupan protein, vitamin C, zat besi terhadap kadar hemoglobin digunakan uji korelasi pearson. Hasil penelitian menunjukkan rerata asupan protein, zat besi dan vitamin C berturut-turut adalah sebesar 25,064 ± 10,055 gram (38,9% RDA (Recommended Daily Allowance), 6,523 ± 2,635 mg (56,33% RDA), dan 69,5% RDA. Rerata kadar hemoglobin sebesar 10,3 ± 1,2 gram/dl. Hasil analisis statistik menunjukkan terdapat hubungan linier antara asupan vitamin C dengan asupan zat besi (r= 0,765), dan antara asupan zat besi dengan kadar hemoglobin( r=0,675). Disimpulkan asupan protein, besi dan vitamin C rendah berhubungan dengan kejadian anemia

The Effect of Oscimum Sanctum to the Thrombocytes Number on Mice

Oscimum sanctum is herbal that was spread widely in Indonesia. Oscimum sanctum contains abundant of substances. One of the functions on Oscimum sanctum was anti-thrombocytes effect. This effect is associated with platelet function as a mechanical plug in the vascular injury during the normal homeostatic response. The disruption in thrombocytes function leads to disturb the blood clotting process. Therefore, The aims of the research were to prove the impact of Oscimum sanctum on the number of thrombocytes. This research used mice that divided into 3 groups, as a group I dose 250 mg/day (Oscimum sanctum infusion), group II dose 500 mg/day and the control group. We used clopidogrel as a positive control to determine the effectiveness of anti platelet effect. Data were analyzed by ANOVA showed that the existence of anti-thrombocyte effect in the Oscimum sanctum dose 500 mg/day was significantly different. This result proved that Oscimum sanctum has anti-thrombocytes effect by decreasing thrombocytes number

Ethanolic Extract of Citrus reticulata Peel Inhibits the Migration of WiDr Colon Cancer Cells

Colorectal cancer is third rank on the cancer cases in Indonesia. To cure the cancer needs big cost and lot of effort. On the other side, the side effect of medicine or chemotherapy on patient need to reduce. Cancer cell spread to other tissue based on its migration and invasion ability. Citrus reticulata peel contains flavonoid such as Tangeretin and Nobiletin, both of this compounds have anticancer activity. The aims of this study is to reveals the potency of ethanol extract of Citrus reticulata peel on the inhibition of migration on WiDr colon cancer cells. The toxicity of ethanol extract of Citurs reticulata peel on WiDr colon cancer line was measured using 3-(4,5-dimethyltiazol-2-il)-2,5-diphenyltrazolium bromide (MTT) assay and investigate the cell migration was using scratch wound healing assay. The ethanol extract of Citrus reticulata peel showed the value of inhibitory concentration 50 (IC50) was 184.5 μg/mL, this result categorize as moderate cytotoxic. Meanwhile the migration assay showed that the deceleration of migration occurred on 0.5 IC50, 0.33 IC50 and 0.25 IC50 during 24 h and 36 h incubation, event thought there were not significant different (p>0.05). The ethanol extract of Citrus reticulata peel has a potential migration inhibition on WiDr cell line.Keywords: Citrus reticulata, WiDr cell line, migratio

Pengaruh Asupan Susu Kedelai Terhadap Ca Darah

Nowadays, soybean milk is known as the alternative substitute for cow milk. Besides contains of calcium, soybean milk also contains of natural substance that similar to estrogens named phytoestrogen. This substance has thought can help calcium absorption from daily dietary. It is therefore soybean milk believed can prevent osteoporosis. Objectives of this research is to understand the effect of consuming soybean milk to blood calcium level in human. This research used pre test-post test only control group design and T-test statistic test. Subject of this research are 10 men that divided into 2 groups. Each group contains of five men, which the group I as experiment group and group II as control group. Result of this research showed that from the control group, there are three subjects who have blood calcium increase, while two subjects have blood calcium decrease. The average of blood calcium level before experiment is 9,53 mg/dl and after experiment is 9,58 mg/dl. So the average of blood calcium increase in negative control group is 0,05 mg/dl (0,58%). Of experiment group, all subjects have blood calcium increase. The average of blood calcium level before consume soybean milk is 9,71 mg/dl and after consume soybean milk is 11,43 mg/dl. So the average of blood calcium increase in experiment group is 1,72 mg/ dl (17,85%). The result of T-test statistic test which done to compare the effect of the two experiments shows the significant difference of end blood calcium level.Susu kedelai akhir-akhir ini mulai dikenal sebagai susu alternatif pengganti susu sapi. Pada susu kedelai selain mengandung kalsium juga terdapat senyawa alami mirip estrogen yang disebut fitoestrogen. Senyawa ini diperkirakan dapat membantu penyerapan kalsium dari makanan yang dikonsumsi sehari-hari. Karena itulah susu kedelai dipercaya mampu menghambat osteoporosis. Tujuan penelitian ini adalah untuk mengetahui pengaruh asupan susu kedelai terhadap kadar Ca darah pada manusia. Rancangan penelitian yang digunakan adalah pretest -post test only control group design, dengan menggunakan subjek sebanyak 10 orang dan dibagi ke dalam 2 kelompok. Masing-masing kelompok terdiri atas 5 orang dimana kelompok I merupakan kelompok perlakuan sedangkan kelompok II sebagai kelompok kontrol dan telah memenuhi kriteria inklusi. Setelah didapatkan hasil kemudian dilakukan uji statistik dengan uji analisa T-test. Hasil penelitian menunjukkan bahwa pada kelompok kontrol terdapat 3 subjek yang mengalami peningkatan kadar kalsium darah sedangkan 2 subjek lainnya mengalami penurunan. Rerata kadar kalsium darah sebelum penelitian 9,53 mg/dl dan setelah penelitian 9,58 mg/dl. Jadi rerata peningkatan pada kelompok kontrol negatif 0,05 mg/dl (0,58 %). Pada kelompok perlakuan kadar kalsium darah semua subjek mengalami peningkatan. Rerata kadar kalsium darah sebelum pemberian susu kedelai 9,71 mg/dl dan setelah pemberian susu kedelai 11,43 mg/dl. Jadi peningkatannya sebesar 1,72 mg/dl (17,85%). Pada subjek kelompok I yang diberi susu kedelai 200 cc selama 14 hari, peningkatan kadar kalsiumnya lebih besar dari pada kelompok II yang tidak di beri susu kedelai. Hasil uji statistik T-test menujukkan adanya perbedaan nyata (p 0,05) pada kadar kalsium serum darah setelah pemberian susu kedelai

PEMBERDAYAAN MASYARAKAT DAN KADER KESEHATAN DALAM UPAYA PENCEGAHAN STUNTING DI GAMPING

Abstrak: Generasi yang berkualitas bersumber pada ibu, melalui ASI. Menyusui memberikan nutrisi terbaik untuk pencegahan stunting kepada bayi. Ironisnya, tidak semua ibu memahami dengan baik, sehingga masih ada yang tidak menyusui secara eksklusif. Di Indonesia, hampir 90% memberikan ASI, namun 49,8% yang memberikan ASI eksklusif selama 6 bulan. Kegiatan ini bertujuan untuk memberikan pengetahuan tentang stunting dan keuntungan menyusui dan diskusi permasalahan yang ada selama menyusui untuk kader dan anggota posyandu Tirtasari. Metode yang dilakukan adalah penyuluhan dan diskusi suka duka menyusui dan interview terarah untuk menggali pengetahuan dan perilaku tentang stunting dan menyusui serta pemberian poster pencegahan stunting dan keuntungan menyusui dan praktek penggunaan alat timbang berat badan digital dan pengukur panjang bayi. Hasil menunjukkan rerata kapasitas pengetahuan tentang stunting 82,61%, namun yang melakukan dalam keseharian 30,43%. Kesimpulan pemberian poster ditempel di rumah diperlukan untuk membantu mengingatkan asi eksklusif. Program seperti ini diharapkan dapat dilakukan berkelanjutan untuk membantu mencegah stunting di Indonesia.Abstract: Qualified generation comes from the mother, through breast milk. Breastfeeding provides the best nutrition for stunting prevention to infants. Many mothers do not understand well, so many of those who do not exclusively breastfeed. In Indonesia 90% doing breast milk; 49.8% doing exclusive breastfeeding. These aims to provide knowledge about stunting and the benefits of breastfeeding and discussion of problems that exist during breastfeeding for cadres and members of the Posyandu Tirtasari. The methods were counseling and discussions on the benefit of breastfeeding, interviews to explore knowledge and behavior about stunting and breastfeeding, providing posters on stunting prevention, the benefits of breastfeeding, the practice of using digital weights and baby lengths. The results show the average knowledge capacity about stunting is 82.61%, but those doing in daily life are 30,43%. The conclusion is that giving posters pasted at home is needed to help remind exclusive breastfeeding. Hopefully these programs doing continuously to help prevent stunting in Indonesia

OPTIMALISASI POJOK BACA MELALUI PEMBEKALAN GURU TK ABA DAN ORANGTUA DALAM MENDAMPINGI ANAK MENDONGENG (BERKISAH)

Agenda bercerita menjadi sangat menarik dan perlu, bilamana dalam rangkaian dongeng/ kisah termuat pesan moral yang dapat diambil oleh anak sebagai pendidikan akhlaq. Itu semua juga ditunjang dari segi fasilitas yang memadai di rumah maupun di Sekolah. Atas dasar ini maka penting untuk melakukanrevitalisasi dengan pengadaankembali fasilitas ruang belajar sebagai ruang berkisah berdongeng. Selain itujuga pengadaan buku-buku penunjang juga diperlukan. Revitalisasi sarana belajar dalamhal ini pojokbelajar (Pojok baca) maka sangat di perlukan bagi anak dan sekolah. Karena budaya literasi harus ditanamkan sejak usia dini bahkan kalau bisa sejak didalam kandungan sudah dibiasakan orangtua untukmembaca. Rutinitas membaca dari orangtua akan ditiru oleh anak. Dengan adanya ProgrampengabdianPKM ini akan mengajak sekolah dan kolaborator untuk merevitalisai pojok belajar dan ditambah kegiatanbelajar anak dan Parental Lecturing tentang budaya literasi yang harus ditanamkan dari lingkungankeluarga melalui peningkatan skill orangtua dalam mendongeng, begitupun kemampuan guru juga perludiasah kembali. Pelaksanannya: 1. Anak dan guru belajar bersama di pojok belajar; mendongeng danberkisah. 2. Pengadaan buku-buku usia anak TK membaca dan menulis Al-Qur’an, buku kisah para nabi, buku dongen fabel, buku menggambar, buku keterampilan otak kiri, kisah-kisah para nabi, sejarah nabi Muhammad dan praktek sholat. 3. Dengan pojok belajar yang nyaman proses belajar juga akan kondusif 4. Parental Lecturing tentang keahlian orangtua dan guru dalam menjadi story teller bagi anak usia TK

Correlation of body mass index on waist circumference and blood pressure

The increasing number of elderly on these recent days demands an improved quality of health for the elderly. Independence of the elderly is important in order to be happy and not to be a burden on their families. Health monitoring continuously is an effort to prevent disruption on the health conditions of the elderly. The health status of elderly people is important to know to follow up on prevention programs for the emergence of certain diseases in the elderly. This study aims to look for potential health problems for elderly people in Gamping, Sleman, DIY, Indonesia. The method of this research was cross sectional analysis using secondary data. Sample collection is consecutive subjects. Subjects were 158 people with a mean age of men (67.8 ± 7.1) years while women were 67.5 ± 7.3 years. The data was analyzed using the bivariate correlation test with CI 99%. The results of the analysis showed that the average body mass index with an average waist circumference was positively correlated (r= 0.66; p: 0.000), but did not correlate with systole pressure (r= -0.009; p= 0.97) diastole (r= 0.093; p= 0.477), age (-0.05; p= 0.71), and gender (r= -0.146; p= 0. 27). The potential health problems among the elderly is the risk of high BMI due to the larger waist circumferenc

Pengaruh Pemberian Jus Belimbing Wuluh (Averrhoa bilimbi L) terhadap Kadar HDL dan LDL-Kolesterol pada Tikus Putih Hiperkolesterolemia

Hiperkolesterolemia terjadi jika kadar kolesterol melebihi batas normal. Belimbing wuluh mempunyai banyak kandungan senyawa yang dibutuhkan manusia diantaranya pektin. Pektin mempunyai peranan dalam menurunkan kadar kolesterol. Penelitian ini bertujuan untuk membuktikan  pengaruh  jus belimbing wuluh terhadap kadar HDL dan LDL-kolesterol pada tikus putih yang mengalami Hiperkolesterolemia. Penelitian ini merupakan penelitian eksperimental dengan rancangan penelitian pre and post test design. Penelitian ini menggunakan tikus putih (Strain Wistar) jantan berusia 2 bulan dengan berat badan rata-rata antara 180 - 260  gram. Jumlah subyek penelitian 16 ekor, dibagi menjadi 4 kelompok masing-masing terdiri dari 4 ekor tikus, yaitu kelompok I adalah kontrol, kelompok II perlakuan dengan dosis 2 ml/200grBB/ hari,Kelompok III dengan perlakuan 3 ml/200grBB/hari dan   kelompok IV dengan perlakuan 4ml/200grBB/ hari). Sebelum diberi perlakuan semua kelompok diberi kuning telur untuk proses hiperkolestrolemia selama 15 hari.Data di uji dengan paired t-test dan one-way anova. Hasil menunjukkan bahwa dosis jus Wuluh yang paling baik dan signifikan (p 0,05) untuk menurunkan LDL-kolesterol dan menaikkan HDL-kolesterol serum darah tikus putih jantan yang mengalami hiperkolesterolemi adalah 4 ml/200grBB/hari. Dapat disimpulkan bahwa jus belimbing wuluh terbukti dapat menurunkan kadar LDL kolesterol dan menaikkan kadar HDL kolesterol pada tikus hiperkolesterolemia.Hypercholesterolemia occurs when cholesterol level exceeds from the normal value. Wuluh star fruit has some beneficial substances for human such as   pectin. Pectin was able to decrease cholesterol levels. This research aims to prove the influence of wuluh starfruit juice on serum HDL and LDL-cholesterol on hipercholesterolemia rats. This research is an experimental research, with the pre- pro test research design. This study used (Wistar strain) 2-month-old male rats which were an average weight between 180 to 260 grams. The Rats, were divided into 4 groups, each was 4 male rats. The group 1  as  placebo and group II used dose 2 ml/200gr weight/day, Group III used  dose 3 ml/200gr weight/day and  group IV used 4ml/ 200gr weight/day. Before treatment, all groups were given egg yolk for 15 days to make hipercholestrolemia. The data analyzed by one-way anova. The results showed that the best dose of wuluh star  Juice and most significant (p 0.05) to lower LDL-cholesterol and raise HDL-cholesterol blood serum  were 4 ml/200gr weight/day).The conclution of the research was Wuluh star fruit juice was  proved decrease LDL Cholesterol and increase HDL cholesterol on Hipercholesterolemia rats