19,972 research outputs found
Sense of agency, associative learning, and schizotypy
Despite the fact that the role of learning is recognised in empirical and theoretical work on sense of agency (SoA), the nature of this learning has, rather surprisingly, received little attention. In the present study we consider the contribution of associative mechanisms to SoA. SoA can be measured quantitatively as a temporal linkage between voluntary actions and their external effects. Using an outcome blocking procedure, it was shown that training action-outcome associations under conditions of increased surprise augmented this temporal linkage. Moreover, these effects of surprise were correlated with schizotypy scores, suggesting that individual differences in higher level experiences are related to associative learning and to its impact on SoA. These results are discussed in terms of models of SoA, and our understanding of disrupted SoA in certain disorders
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Genome-wide patterns of polymorphism in an inbred line of the African malaria mosquito Anopheles gambiae.
Anopheles gambiae is a major mosquito vector of malaria in Africa. Although increased use of insecticide-based vector control tools has decreased malaria transmission, elimination is likely to require novel genetic control strategies. It can be argued that the absence of an A. gambiae inbred line has slowed progress toward genetic vector control. In order to empower genetic studies and enable precise and reproducible experimentation, we set out to create an inbred line of this species. We found that amenability to inbreeding varied between populations of A. gambiae. After full-sib inbreeding for ten generations, we genotyped 112 individuals--56 saved prior to inbreeding and 56 collected after inbreeding--at a genome-wide panel of single nucleotide polymorphisms (SNPs). Although inbreeding dramatically reduced diversity across much of the genome, we discovered numerous, discrete genomic blocks that maintained high heterozygosity. For one large genomic region, we were able to definitively show that high diversity is due to the persistent polymorphism of a chromosomal inversion. Inbred lines in other eukaryotes often exhibit a qualitatively similar retention of polymorphism when typed at a small number of markers. Our whole-genome SNP data provide the first strong, empirical evidence supporting associative overdominance as the mechanism maintaining higher than expected diversity in inbred lines. Although creation of A. gambiae lines devoid of nearly all polymorphism may not be feasible, our results provide critical insights into how more fully isogenic lines can be created
From patterned response dependency to structured covariate dependency: categorical-pattern-matching
Data generated from a system of interest typically consists of measurements
from an ensemble of subjects across multiple response and covariate features,
and is naturally represented by one response-matrix against one
covariate-matrix. Likely each of these two matrices simultaneously embraces
heterogeneous data types: continuous, discrete and categorical. Here a matrix
is used as a practical platform to ideally keep hidden dependency among/between
subjects and features intact on its lattice. Response and covariate dependency
is individually computed and expressed through mutliscale blocks via a newly
developed computing paradigm named Data Mechanics. We propose a categorical
pattern matching approach to establish causal linkages in a form of information
flows from patterned response dependency to structured covariate dependency.
The strength of an information flow is evaluated by applying the combinatorial
information theory. This unified platform for system knowledge discovery is
illustrated through five data sets. In each illustrative case, an information
flow is demonstrated as an organization of discovered knowledge loci via
emergent visible and readable heterogeneity. This unified approach
fundamentally resolves many long standing issues, including statistical
modeling, multiple response, renormalization and feature selections, in data
analysis, but without involving man-made structures and distribution
assumptions. The results reported here enhance the idea that linking patterns
of response dependency to structures of covariate dependency is the true
philosophical foundation underlying data-driven computing and learning in
sciences.Comment: 32 pages, 10 figures, 3 box picture
Characterizing and Subsetting Big Data Workloads
Big data benchmark suites must include a diversity of data and workloads to
be useful in fairly evaluating big data systems and architectures. However,
using truly comprehensive benchmarks poses great challenges for the
architecture community. First, we need to thoroughly understand the behaviors
of a variety of workloads. Second, our usual simulation-based research methods
become prohibitively expensive for big data. As big data is an emerging field,
more and more software stacks are being proposed to facilitate the development
of big data applications, which aggravates hese challenges. In this paper, we
first use Principle Component Analysis (PCA) to identify the most important
characteristics from 45 metrics to characterize big data workloads from
BigDataBench, a comprehensive big data benchmark suite. Second, we apply a
clustering technique to the principle components obtained from the PCA to
investigate the similarity among big data workloads, and we verify the
importance of including different software stacks for big data benchmarking.
Third, we select seven representative big data workloads by removing redundant
ones and release the BigDataBench simulation version, which is publicly
available from http://prof.ict.ac.cn/BigDataBench/simulatorversion/.Comment: 11 pages, 6 figures, 2014 IEEE International Symposium on Workload
Characterizatio
Nonsemisimple Fusion Algebras and the Verlinde Formula
We find a nonsemisimple fusion algebra F_p associated with each (1,p)
Virasoro model. We present a nonsemisimple generalization of the Verlinde
formula which allows us to derive F_p from modular transformations of
characters.Comment: LaTeX (amsart, xypic, times), 35p
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