A Multi-Method Evaluation Of A Guideline Based Clinical Decision Support Intervention On Provider Ordering Behavior, System Acceptance And Inter-Professional Communication

Background and aims: Unnecessary variation in the delivery of patient care is well documented in the medical literature; evidence-based clinical practice is critical for improving the quality of care. Clinical decision support systems (CDSS) are promising tools for improving the systematic integration of evidence into clinical practice. This study evaluated a CDSS in a domain of care that had not yet been explored—namely, decision support for venous catheter selection. This dissertation study aimed to (1) evaluate the effect of this CDSS on provider ordering behavior before and after implementation and explore the differential impact of this tool by provider type and service and (2) identify organizational, individual, usability, and workflow factors that impact CDSS acceptance by physicians and advanced practice nurses and to elicit information about the impact of this system on communication between providers and the nurse-led vascular access team. Methods: This was a multi-method study. Aim one was single group pre-post analysis of longitudinal data. Variables included those related to patient and provider level factors. The main analysis was conducted with linear regression models with random effects to account for clustering of data. We conducted semi-structured interviews for aim two and use conventional qualitative content analysis to identify themes. Results: We found mixed results in the impact of the CDSS on provider ordering behavior. While the CDSS did not have an impact on the number of venous catheters ordered, we saw a statistically and clinically significant decrease in the proportion of double lumen catheters ordered. Findings for the qualitative aim showed that the CDSS improved process efficiency and inter-professional communication. We found that it also facilitated education for evidence based practice for novice providers. Discussion: This dissertation study showed a clear impact of the CDSS on double lumen catheter ordering, which has implications for patient outcomes. Furthermore, we found impacts by provider type. Additional work is needed to evaluate this CDSS in other settings and to further assess differential impacts by provider type

An investigation of healthcare professionals’ experiences of training and using electronic prescribing systems: four literature reviews and two qualitative studies undertaken in the UK hospital context

Electronic prescribing (ePrescribing) is the process of ordering medicines electronically for a patient and has been associated with reduced medication errors and improved patient safety. However, these systems have also been associated with unintended adverse consequences. There is a lack of published research about users’ experiences of these systems in UK hospitals. The aim of this research was therefore to firstly describe the literature pertaining to the recent developments and persisting issues with ePrescribing and clinical decision support systems (CDS) (chapter 2). Two further systematic literature reviews (chapters 3 and 4) were then conducted to understand the unintended consequences of ePrescribing and clinical decision support (CDS) systems across both adult and paediatric patients. These revealed a taxonomy of factors, which have contributed to errors during use of these systems e.g., the screen layout, default settings and inappropriate drug-dosage support. The researcher then conducted a qualitative study (chapters 7-10) to explore users’ experiences of using and being trained to use ePrescribing systems. This study involved conducting semi-structured interviews and observations, which revealed key challenges facing users, including issues with using the ‘Medication List’ and how information was presented. Users experienced benefits and challenges when customising the system, including the screen display; however, the process was sometimes overly complex. Users also described the benefits and challenges associated with different forms of interruptive and passive CDS. Order sets, for instance, encouraged more efficient prescribing, yet users often found them difficult to find within the system. A lack of training resulted in users failing to use all features of the ePrescribing system and left some healthcare staff feeling underprepared for using the system in their role. A further literature review (chapter 5) was then performed to complement emerging themes relating to how users were trained to use ePrescribing systems, which were generated as part of a qualitative study. This review revealed the range of approaches used to train users and the need for further research in this area. The literature review and qualitative study-based findings led to a follow-on study (chapter 10), whereby the researcher conducted semi-structured interviews to examine how users were trained to use ePrescribing systems across four NHS Hospital Trusts. A range of approaches were used to train users; tailored training, using clinically specific scenarios or matching the user’s profession to that of the trainer were preferred over lectures and e-learning may offer an efficient way of training large numbers of staff. However, further research is needed to investigate this and whether alternative approaches such as the use of students as trainers could be useful. This programme of work revealed the importance of human factors and user involvement in the design and ongoing development of ePrescribing systems. Training also played a role in users’ experiences of using the system and hospitals should carefully consider the training approaches used. This thesis provides recommendations gathered from the literature and primary data collection that can help inform organisations, system developers and further research in this area