Histopathological image analysis : a review

Over the past decade, dramatic increases in computational power and improvement in image analysis algorithms have allowed the development of powerful computer-assisted analytical approaches to radiological data. With the recent advent of whole slide digital scanners, tissue histopathology slides can now be digitized and stored in digital image form. Consequently, digitized tissue histopathology has now become amenable to the application of computerized image analysis and machine learning techniques. Analogous to the role of computer-assisted diagnosis (CAD) algorithms in medical imaging to complement the opinion of a radiologist, CAD algorithms have begun to be developed for disease detection, diagnosis, and prognosis prediction to complement the opinion of the pathologist. In this paper, we review the recent state of the art CAD technology for digitized histopathology. This paper also briefly describes the development and application of novel image analysis technology for a few specific histopathology related problems being pursued in the United States and Europe

Modeling of evolving textures using granulometries

This chapter describes a statistical approach to classification of dynamic texture images, called parallel evolution functions (PEFs). Traditional classification methods predict texture class membership using comparisons with a finite set of predefined texture classes and identify the closest class. However, where texture images arise from a dynamic texture evolving over time, estimation of a time state in a continuous evolutionary process is required instead. The PEF approach does this using regression modeling techniques to predict time state. It is a flexible approach which may be based on any suitable image features. Many textures are well suited to a morphological analysis and the PEF approach uses image texture features derived from a granulometric analysis of the image. The method is illustrated using both simulated images of Boolean processes and real images of corrosion. The PEF approach has particular advantages for training sets containing limited numbers of observations, which is the case in many real world industrial inspection scenarios and for which other methods can fail or perform badly. [41] G.W. Horgan, Mathematical morphology for analysing soil structure from images, European Journal of Soil Science, vol. 49, pp. 161–173, 1998. [42] G.W. Horgan, C.A. Reid and C.A. Glasbey, Biological image processing and enhancement, Image Processing and Analysis, A Practical Approach, R. Baldock and J. Graham, eds., Oxford University Press, Oxford, UK, pp. 37–67, 2000. [43] B.B. Hubbard, The World According to Wavelets: The Story of a Mathematical Technique in the Making, A.K. Peters Ltd., Wellesley, MA, 1995. [44] H. Iversen and T. Lonnestad. An evaluation of stochastic models for analysis and synthesis of gray-scale texture, Pattern Recognition Letters, vol. 15, pp. 575–585, 1994. [45] A.K. Jain and F. Farrokhnia, Unsupervised texture segmentation using Gabor filters, Pattern Recognition, vol. 24(12), pp. 1167–1186, 1991. [46] T. Jossang and F. Feder, The fractal characterization of rough surfaces, Physica Scripta, vol. T44, pp. 9–14, 1992. [47] A.K. Katsaggelos and T. Chun-Jen, Iterative image restoration, Handbook of Image and Video Processing, A. Bovik, ed., Academic Press, London, pp. 208–209, 2000. [48] M. K¨oppen, C.H. Nowack and G. R¨osel, Pareto-morphology for color image processing, Proceedings of SCIA99, 11th Scandinavian Conference on Image Analysis 1, Kangerlussuaq, Greenland, pp. 195–202, 1999. [49] S. Krishnamachari and R. Chellappa, Multiresolution Gauss-Markov random field models for texture segmentation, IEEE Transactions on Image Processing, vol. 6(2), pp. 251–267, 1997. [50] T. Kurita and N. Otsu, Texture classification by higher order local autocorrelation features, Proceedings of ACCV93, Asian Conference on Computer Vision, Osaka, pp. 175–178, 1993. [51] S.T. Kyvelidis, L. Lykouropoulos and N. Kouloumbi, Digital system for detecting, classifying, and fast retrieving corrosion generated defects, Journal of Coatings Technology, vol. 73(915), pp. 67–73, 2001. [52] Y. Liu, T. Zhao and J. Zhang, Learning multispectral texture features for cervical cancer detection, Proceedings of 2002 IEEE International Symposium on Biomedical Imaging: Macro to Nano, pp. 169–172, 2002. [53] G. McGunnigle and M.J. Chantler, Modeling deposition of surface texture, Electronics Letters, vol. 37(12), pp. 749–750, 2001. [54] J. McKenzie, S. Marshall, A.J. Gray and E.R. Dougherty, Morphological texture analysis using the texture evolution function, International Journal of Pattern Recognition and Artificial Intelligence, vol. 17(2), pp. 167–185, 2003. [55] J. McKenzie, Classification of dynamically evolving textures using evolution functions, Ph.D. Thesis, University of Strathclyde, UK, 2004. [56] S.G. Mallat, Multiresolution approximations and wavelet orthonormal bases of L2(R), Transactions of the American Mathematical Society, vol. 315, pp. 69–87, 1989. [57] S.G. Mallat, A theory for multiresolution signal decomposition: the wavelet representation, IEEE Transactions on Pattern Analysis and Machine Intelligence, vol. 11, pp. 674–693, 1989. [58] B.S. Manjunath and W.Y. Ma, Texture features for browsing and retrieval of image data, IEEE Transactions on Pattern Analysis and Machine Intelligence, vol. 18, pp. 837–842, 1996. [59] B.S. Manjunath, G.M. Haley and W.Y. Ma, Multiband techniques for texture classification and segmentation, Handbook of Image and Video Processing, A. Bovik, ed., Academic Press, London, pp. 367–381, 2000. [60] G. Matheron, Random Sets and Integral Geometry, Wiley Series in Probability and Mathematical Statistics, John Wiley and Sons, New York, 1975

Advances in Hyperspectral Image Classification: Earth monitoring with statistical learning methods

Hyperspectral images show similar statistical properties to natural grayscale or color photographic images. However, the classification of hyperspectral images is more challenging because of the very high dimensionality of the pixels and the small number of labeled examples typically available for learning. These peculiarities lead to particular signal processing problems, mainly characterized by indetermination and complex manifolds. The framework of statistical learning has gained popularity in the last decade. New methods have been presented to account for the spatial homogeneity of images, to include user's interaction via active learning, to take advantage of the manifold structure with semisupervised learning, to extract and encode invariances, or to adapt classifiers and image representations to unseen yet similar scenes. This tutuorial reviews the main advances for hyperspectral remote sensing image classification through illustrative examples.Comment: IEEE Signal Processing Magazine, 201

Signal processing algorithms for enhanced image fusion performance and assessment

The dissertation presents several signal processing algorithms for image fusion in noisy multimodal conditions. It introduces a novel image fusion method which performs well for image sets heavily corrupted by noise. As opposed to current image fusion schemes, the method has no requirements for a priori knowledge of the noise component. The image is decomposed with Chebyshev polynomials (CP) being used as basis functions to perform fusion at feature level. The properties of CP, namely fast convergence and smooth approximation, renders it ideal for heuristic and indiscriminate denoising fusion tasks. Quantitative evaluation using objective fusion assessment methods show favourable performance of the proposed scheme compared to previous efforts on image fusion, notably in heavily corrupted images. The approach is further improved by incorporating the advantages of CP with a state-of-the-art fusion technique named independent component analysis (ICA), for joint-fusion processing based on region saliency. Whilst CP fusion is robust under severe noise conditions, it is prone to eliminating high frequency information of the images involved, thereby limiting image sharpness. Fusion using ICA, on the other hand, performs well in transferring edges and other salient features of the input images into the composite output. The combination of both methods, coupled with several mathematical morphological operations in an algorithm fusion framework, is considered a viable solution. Again, according to the quantitative metrics the results of our proposed approach are very encouraging as far as joint fusion and denoising are concerned. Another focus of this dissertation is on a novel metric for image fusion evaluation that is based on texture. The conservation of background textural details is considered important in many fusion applications as they help define the image depth and structure, which may prove crucial in many surveillance and remote sensing applications. Our work aims to evaluate the performance of image fusion algorithms based on their ability to retain textural details from the fusion process. This is done by utilising the gray-level co-occurrence matrix (GLCM) model to extract second-order statistical features for the derivation of an image textural measure, which is then used to replace the edge-based calculations in an objective-based fusion metric. Performance evaluation on established fusion methods verifies that the proposed metric is viable, especially for multimodal scenarios

Assessment of Levee Erosion using Image Processing and Contextual Cueing

Soil erosion is one of the most severe land degradation problems afflicting many parts of the world where topography of the land is relatively steep. Due to inaccessibility to steep terrain, such as slopes in levees and forested mountains, advanced data processing techniques can be used to identify and assess high risk erosion zones. Unlike existing methods that require human observations, which can be expensive and error-prone, the proposed approach uses a fully automated algorithm to indicate when an area is at risk of erosion; this is accomplished by processing Landsat and aerial images taken using drones. In this paper the image processing algorithm is presented, which can be used to identify the scene of an image by classifying it in one of six categories: levee, mountain, forest, degraded forest, cropland, grassland or orchard. This paper focuses on automatic scene detection using global features with local representations to show the gradient structure of an image. The output of this work counts as a contextual cueing and can be used in erosion assessment, which can be used to predict erosion risks in levees. We also discuss the environmental implications of deferred erosion control in levees

Alphabet-based Multisensory Data Fusion and Classification using Factor Graphs

The way of multisensory data integration is a crucial step of any data fusion method. Different physical types of sensors (optic, thermal, acoustic, or radar) with different resolutions, and different types of GIS digital data (elevation, vector map) require a proper method for data integration. Incommensurability of the data may not allow to use conventional statistical methods for fusion and processing of the data. A correct and established way of multisensory data integration is required to deal with such incommensurable data as the employment of an inappropriate methodology may lead to errors in the fusion process. To perform a proper multisensory data fusion several strategies were developed (Bayesian, linear (log linear) opinion pool, neural networks, fuzzy logic approaches). Employment of these approaches is motivated by weighted consensus theory, which lead to fusion processes that are correctly performed for the variety of data properties