Modeling and Simulation in Engineering

This book provides an open platform to establish and share knowledge developed by scholars, scientists, and engineers from all over the world, about various applications of the modeling and simulation in the design process of products, in various engineering fields. The book consists of 12 chapters arranged in two sections (3D Modeling and Virtual Prototyping), reflecting the multidimensionality of applications related to modeling and simulation. Some of the most recent modeling and simulation techniques, as well as some of the most accurate and sophisticated software in treating complex systems, are applied. All the original contributions in this book are jointed by the basic principle of a successful modeling and simulation process: as complex as necessary, and as simple as possible. The idea is to manipulate the simplifying assumptions in a way that reduces the complexity of the model (in order to make a real-time simulation), but without altering the precision of the results

Hidden Markov Models

Hidden Markov Models (HMMs), although known for decades, have made a big career nowadays and are still in state of development. This book presents theoretical issues and a variety of HMMs applications in speech recognition and synthesis, medicine, neurosciences, computational biology, bioinformatics, seismology, environment protection and engineering. I hope that the reader will find this book useful and helpful for their own research

ChatGPT for Shaping the Future of Dentistry: The Potential of Multi-Modal Large Language Model

The ChatGPT, a lite and conversational variant of Generative Pretrained Transformer 4 (GPT-4) developed by OpenAI, is one of the milestone Large Language Models (LLMs) with billions of parameters. LLMs have stirred up much interest among researchers and practitioners in their impressive skills in natural language processing tasks, which profoundly impact various fields. This paper mainly discusses the future applications of LLMs in dentistry. We introduce two primary LLM deployment methods in dentistry, including automated dental diagnosis and cross-modal dental diagnosis, and examine their potential applications. Especially, equipped with a cross-modal encoder, a single LLM can manage multi-source data and conduct advanced natural language reasoning to perform complex clinical operations. We also present cases to demonstrate the potential of a fully automatic Multi-Modal LLM AI system for dentistry clinical application. While LLMs offer significant potential benefits, the challenges, such as data privacy, data quality, and model bias, need further study. Overall, LLMs have the potential to revolutionize dental diagnosis and treatment, which indicates a promising avenue for clinical application and research in dentistry

Abstraction, aggregation and recursion for generating accurate and simple classifiers

An important goal of inductive learning is to generate accurate and compact classifiers from data. In a typical inductive learning scenario, instances in a data set are simply represented as ordered tuples of attribute values. In our research, we explore three methodologies to improve the accuracy and compactness of the classifiers: abstraction, aggregation, and recursion;Firstly, abstraction is aimed at the design and analysis of algorithms that generate and deal with taxonomies for the construction of compact and robust classifiers. In many applications of the data-driven knowledge discovery process, taxonomies have been shown to be useful in constructing compact, robust, and comprehensible classifiers. However, in many application domains, human-designed taxonomies are unavailable. We introduce algorithms for automated construction of taxonomies inductively from both structured (such as UCI Repository) and unstructured (such as text and biological sequences) data. We introduce AVT-Learner, an algorithm for automated construction of attribute value taxonomies (AVT) from data, and Word Taxonomy Learner (WTL), an algorithm for automated construction of word taxonomy from text and sequence data. We describe experiments on the UCI data sets and compare the performance of AVT-NBL (an AVT-guided Naive Bayes Learner) with that of the standard Naive Bayes Learner (NBL). Our results show that the AVTs generated by AVT-Learner are compeitive with human-generated AVTs (in cases where such AVTs are available). AVT-NBL using AVTs generated by AVT-Learner achieves classification accuracies that are comparable to or higher than those obtained by NBL; and the resulting classifiers are significantly more compact than those generated by NBL. Similarly, our experimental results of WTL and WTNBL on protein localization sequences and Reuters newswire text categorization data sets show that the proposed algorithms can generate Naive Bayes classifiers that are more compact and often more accurate than those produced by standard Naive Bayes learner for the Multinomial Model;Secondly, we apply aggregation to construct features as a multiset of values for the intrusion detection task. For this task, we propose a bag of system calls representation for system call traces and describe misuse and anomaly detection results on the University of New Mexico (UNM) and MIT Lincoln Lab (MIT LL) system call sequences with the proposed representation. With the feature representation as input, we compare the performance of several machine learning techniques for misuse detection and show experimental results on anomaly detection. The results show that standard machine learning and clustering techniques using the simple bag of system calls representation based on the system call traces generated by the operating system\u27s kernel is effective and often performs better than approaches that use foreign contiguous sequences in detecting intrusive behaviors of compromised processes;Finally, we construct a set of classifiers by recursive application of the Naive Bayes learning algorithms. Naive Bayes (NB) classifier relies on the assumption that the instances in each class can be described by a single generative model. This assumption can be restrictive in many real world classification tasks. We describe recursive Naive Bayes learner (RNBL), which relaxes this assumption by constructing a tree of Naive Bayes classifiers for sequence classification, where each individual NB classifier in the tree is based on an event model (one model for each class at each node in the tree). In our experiments on protein sequences, Reuters newswire documents and UC-Irvine benchmark data sets, we observe that RNBL substantially outperforms NB classifier. Furthermore, our experiments on the protein sequences and the text documents show that RNBL outperforms C4.5 decision tree learner (using tests on sequence composition statistics as the splitting criterion) and yields accuracies that are comparable to those of support vector machines (SVM) using similar information

Intelligent Systems

This book is dedicated to intelligent systems of broad-spectrum application, such as personal and social biosafety or use of intelligent sensory micro-nanosystems such as "e-nose", "e-tongue" and "e-eye". In addition to that, effective acquiring information, knowledge management and improved knowledge transfer in any media, as well as modeling its information content using meta-and hyper heuristics and semantic reasoning all benefit from the systems covered in this book. Intelligent systems can also be applied in education and generating the intelligent distributed eLearning architecture, as well as in a large number of technical fields, such as industrial design, manufacturing and utilization, e.g., in precision agriculture, cartography, electric power distribution systems, intelligent building management systems, drilling operations etc. Furthermore, decision making using fuzzy logic models, computational recognition of comprehension uncertainty and the joint synthesis of goals and means of intelligent behavior biosystems, as well as diagnostic and human support in the healthcare environment have also been made easier

Evolvable Smartphone-Based Point-of-Care Systems For In-Vitro Diagnostics

Recent developments in the life-science -omics disciplines, together with advances in micro and nanoscale technologies offer unprecedented opportunities to tackle some of the major healthcare challenges of our time. Lab-on-Chip technologies coupled with smart-devices in particular, constitute key enablers for the decentralization of many in-vitro medical diagnostics applications to the point-of-care, supporting the advent of a preventive and personalized medicine. Although the technical feasibility and the potential of Lab-on-Chip/smart-device systems is repeatedly demonstrated, direct-to-consumer applications remain scarce. This thesis addresses this limitation. System evolvability is a key enabler to the adoption and long-lasting success of next generation point-of-care systems by favoring the integration of new technologies, streamlining the reengineering efforts for system upgrades and limiting the risk of premature system obsolescence. Among possible implementation strategies, platform-based design stands as a particularly suitable entry point. One necessary condition, is for change-absorbing and change-enabling mechanisms to be incorporated in the platform architecture at initial design-time. Important considerations arise as to where in Lab-on-Chip/smart-device platforms can these mechanisms be integrated, and how to implement them. Our investigation revolves around the silicon-nanowire biological field effect transistor, a promising biosensing technology for the detection of biological analytes at ultra low concentrations. We discuss extensively the sensitivity and instrumentation requirements set by the technology before we present the design and implementation of an evolvable smartphone-based platform capable of interfacing lab-on-chips embedding such sensors. We elaborate on the implementation of various architectural patterns throughout the platform and present how these facilitated the evolution of the system towards one accommodating for electrochemical sensing. Model-based development was undertaken throughout the engineering process. A formal SysML system model fed our evolvability assessment process. We introduce, in particular, a model-based methodology enabling the evaluation of modular scalability: the ability of a system to scale the current value of one of its specification by successively reengineering targeted system modules. The research work presented in this thesis provides a roadmap for the development of evolvable point-of-care systems, including those targeting direct-to-consumer applications. It extends from the early identification of anticipated change, to the assessment of the ability of a system to accommodate for these changes. Our research should thus interest industrials eager not only to disrupt, but also to last in a shifting socio-technical paradigm

Psyche, Signals and Systems

For a century or so, the multidisciplinary nature of neuroscience has left the field fractured into distinct areas of research. In particular, the subjects of consciousness and perception present unique challenges in the attempt to build a unifying understanding bridging between the micro-, meso-, and macro-scales of the brain and psychology. This chapter outlines an integrated view of the neurophysiological systems, psychophysical signals, and theoretical considerations related to consciousness. First, we review the signals that correlate to consciousness during psychophysics experiments. We then review the underlying neural mechanisms giving rise to these signals. Finally, we discuss the computational and theoretical functions of such neural mechanisms, and begin to outline means in which these are related to ongoing theoretical research

Evolutionary Computation

This book presents several recent advances on Evolutionary Computation, specially evolution-based optimization methods and hybrid algorithms for several applications, from optimization and learning to pattern recognition and bioinformatics. This book also presents new algorithms based on several analogies and metafores, where one of them is based on philosophy, specifically on the philosophy of praxis and dialectics. In this book it is also presented interesting applications on bioinformatics, specially the use of particle swarms to discover gene expression patterns in DNA microarrays. Therefore, this book features representative work on the field of evolutionary computation and applied sciences. The intended audience is graduate, undergraduate, researchers, and anyone who wishes to become familiar with the latest research work on this field