A Survey on Deep Learning in Medical Image Analysis

Deep learning algorithms, in particular convolutional networks, have rapidly become a methodology of choice for analyzing medical images. This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes over 300 contributions to the field, most of which appeared in the last year. We survey the use of deep learning for image classification, object detection, segmentation, registration, and other tasks and provide concise overviews of studies per application area. Open challenges and directions for future research are discussed.Comment: Revised survey includes expanded discussion section and reworked introductory section on common deep architectures. Added missed papers from before Feb 1st 201

Intelligent Cervical Spine Fracture Detection Using Deep Learning Methods

Cervical spine fractures constitute a critical medical emergency, with the potential for lifelong paralysis or even fatality if left untreated or undetected. Over time, these fractures can deteriorate without intervention. To address the lack of research on the practical application of deep learning techniques for the detection of spine fractures, this study leverages a dataset containing both cervical spine fractures and non-fractured computed tomography images. This paper introduces a two-stage pipeline designed to identify the presence of cervical vertebrae in each image slice and pinpoint the location of fractures. In the first stage, a multi-input network, incorporating image and image metadata, is trained. This network is based on the Global Context Vision Transformer, and its performance is benchmarked against popular deep learning image classification model. In the second stage, a YOLOv8 model is trained to detect fractures within the images, and its effectiveness is compared to YOLOv5. The obtained results indicate that the proposed algorithm significantly reduces the workload of radiologists and enhances the accuracy of fracture detection

Unsupervised domain adaptation for vertebrae detection and identification in 3D CT volumes using a domain sanity loss

A variety of medical computer vision applications analyze 2D slices of computed tomography (CT) scans, whereas axial slices from the body trunk region are usually identified based on their relative position to the spine. A limitation of such systems is that either the correct slices must be extracted manually or labels of the vertebrae are required for each CT scan to develop an automated extraction system. In this paper, we propose an unsupervised domain adaptation (UDA) approach for vertebrae detection and identification based on a novel Domain Sanity Loss (DSL) function. With UDA the model’s knowledge learned on a publicly available (source) data set can be transferred to the target domain without using target labels, where the target domain is defined by the specific setup (CT modality, study protocols, applied pre- and processing) at the point of use (e.g., a specific clinic with its specific CT study protocols). With our approach, a model is trained on the source and target data set in parallel. The model optimizes a supervised loss for labeled samples from the source domain and the DSL loss function based on domain-specific “sanity checks” for samples from the unlabeled target domain. Without using labels from the target domain, we are able to identify vertebra centroids with an accuracy of 72.8%. By adding only ten target labels during training the accuracy increases to 89.2%, which is on par with the current state-of-the-art for full supervised learning, while using about 20 times less labels. Thus, our model can be used to extract 2D slices from 3D CT scans on arbitrary data sets fully automatically without requiring an extensive labeling effort, contributing to the clinical adoption of medical imaging by hospitals